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http://dx.doi.org/10.22246/jikm.2017.38.4.443

An Overview of the Applicability of Oryung-san as an Antihypertensive Agent  

Jeong, Min-jeong (Dept. of Pediatrics, College of Korean Medicine, Woo-Suk University)
Kang, Ki-wan (Dept. of Internal Medicine, College of Korean Medicine, Woo-Suk University)
Kang, Ja-yeon (Dept. of Internal Medicine, College of Korean Medicine, Woo-Suk University)
Yoon, Jee-hyun (Dept. of Herbology, College of Korean Medicine, Woo-Suk University)
Choi, Yoo-min (Dept. of Acupuncture, College of Korean Medicine, Woo-Suk University)
Kim, Hong-jun (Dept. of Prescription, College of Korean Medicine, Woo-Suk University)
Sun, Seung-ho (Dept. of Internal Medicine, College of Korean Medicine, Sang-Ji University)
Jang, In-soo (Dept. of Internal Medicine, College of Korean Medicine, Woo-Suk University)
Publication Information
The Journal of Internal Korean Medicine / v.38, no.4, 2017 , pp. 443-454 More about this Journal
Abstract
Objectives: This study assessed the application of Oryung-san (Wuling-san or Gorei-san), a common diuretic in traditional medicine, as an antihypertensive agent. Methods: Experimental studies of the pharmacological properties of Oryung-san, including diuretic action and lowering effects on blood pressure, and toxicology and clinical trials were reviewed. Results: In pharmacology, various, relatively safe diuretics are used to lower blood pressure and are the oldest and most studied antihypertensive agents. Despite many new drug approvals, antihypertensive diuretics are frequently used in Korea and Japan where high levels of sodium uptake are common. Oryung-san has been demonstrated to have diuretic, antihypertensive, and nephroprotective effects. Conclusions: Oryung-san might be effective for lowering blood pressure based on the results of this literature review. Further evaluations and large-scale clinical trials of Oryung-san to treat primary hypertension are warranted.
Keywords
herbal medication; hypertension; blood pressure; Korean medicine; Oryung-san; Wuling-san; Gorei-san;
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Times Cited By KSCI : 4  (Citation Analysis)
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