• The Journal of the Acoustical Society of Korea
• /
• v.42 no.5
• /
• pp.412-421
• /
• 2023

Ultrasound brain stimulation is spot-lighted by its capability of inducing brain cell activation in a localized deep brain region and ultimately treating impaired brain function while the efficiency and directivity of neural modulation are highly dependent on types of stimulus waveforms. Therefore, to optimize the types of stimulation parameters, we propose a cell-cultivable ultrasonic transducer having a series stack of a spin-coated polymer piezoelectric element (Poly-vinylidene fluoride-trifluorethylene, PVDF-TrFE) and a parylene insulating layer enhancing output acoustic pressure on a glass-coverslip which is commonly used in culturing cells. Due to the uniformity and high accuracy of stimulus waveform, tens of neuronal cell responses located on the transducer surface can be recorded simultaneously with fluorescence microscopy. By averaging the cell response traces from tens of cells, small changes to the low intensity ultrasound stimulations can be identified. In addition, the reduction of stimulus distortions made by standing wave generated from reflections between the transducers and other strong reflectors can be achieved by placing acoustic absorbers. Through the proposed ultrasound transducer, we could successfully observe the calcium responses induced by low-intensity ultrasound stimulation of 6 MHz, 0.2 MPa in astrocytes cultured on the transducer surface.

• Journal of the Korea Society for Simulation
• /
• v.19 no.4
• /
• pp.77-87
• /
• 2010

Currently, our society has been changed from the industrial society to the information society. As the war progresses to Information Warfare, Network-Centric Warfare, Long-Range Precision Engagement and Robot Warfare, the military should advance to High-tech Scientific force. For this creation of the war potential, it is regarded as the warfighting experiment is a critical method. Surely it is rational that LVC(Live Virtual Constructive simulation) is desirable to make the warfighting experiment. But because it is limited by the cost, the time, the place and the resource, the constructive simulation(M&S : Modeling&Simulation) is a good tool to solve those problems. There are some studies about the evaluation process for developing the model, but it is unsatisfying in the process of the constructive simulations' operation. This study focuses on the way of constructive simulation operation, which is supplied with the evaluation process(VV&A : Verification Validation & Accreditation). We introduce the example of the rear area operation simulation for "appropriateness evaluation to the organization of logistic corps" by the AWAM(Army Weapon Analysis Model). This study presents the effective methods of the constructive simulations, which is based on the reliable evaluation process, so it will contribute to the warfighting experiments.

• Clean Technology
• /
• v.15 no.2
• /
• pp.81-90
• /
• 2009

In this study various cleaning evaluation methods were tested and comparatively evaluated to help cleaning industry. In order to select alternative cleaning agents objectively and systematically, various cleaning evaluation methods such as gravimetric, optically simulated electron emission (OSEE), contact angle, and analytical instrument methods were employed for cleaning contaminants such as flux, solder and grease. The analytical instruments used in this work were Fourier transform infrared spectroscopy (FTIR), ultraviolet visible spectroscopy (UV-VIS) and high performance liquid chromatography (HPLC). The gravimetric method was able to measure cleaning efficiencies easily and simply, but it was not easy to analyze them precisely because of its limitation in the gravimetric measurement. However, the OSEE technique was able to measure quickly and precisely the clean ability of cleaning agents in comparison with the gravimetric method. The contact angle method was found to be necessary for taking special precaution in its application to the cleaning evaluation due to possible formation of tiny organic film on the substrate surface which might be generated from contaminants and cleaning agents. In case of precision analysis that cannot be done by gravimetric method, fine analytical instruments such as UV-VIS, FTIR and HPLC could be used in analyzing trace amount of flux, solder and grease quantitatively, which were extracted from the surface by special solvents.

• The Journal of the Convergence on Culture Technology
• /
• v.9 no.1
• /
• pp.691-695
• /
• 2023

Currently, the utilization of measurement results of the automated measurement system is very low and is at the level of providing only fragmentary measurement results. In this study, we are going to study a structure behavior analysis 3D display system with high precision and reliability for automated measurement data obtained by constructing big data by transmitting massive data values measured in real time to the cloud and using a Python-based algorithm. As a result of the study, as a system that can evaluate the behavior of a structure to a manager in real time, it provides analysis data in real time without significant restrictions regardless of the type of measurement data and sensor, and derived it as a 3D display. In addition, it was analyzed that the manager could grasp the behavior graph of the structure in real time and more easily judge the derivation of the weak part of the structure through data analysis. In the future, by analyzing the behavior of structures in three dimensions using past and present data, it is expected that more effective measurement results can be obtained in terms of repair, reinforcement, and maintenance of realistic structures.

• Journal of the Korean Geosynthetics Society
• /
• v.22 no.2
• /
• pp.1-12
• /
• 2023

Research on the causes of landslides and prediction of vulnerable areas is being conducted globally. This study aims to predict the effective soil depth, a critical element in analyzing and forecasting landslide disasters, using topographic information. Topographic data from various institutions were collected and assigned as attribute information to a 100 m × 100 m grid, which was then reduced through data grading. The study predicted effective soil depth for two cases: three depths (shallow, normal, deep) and five depths (very shallow, shallow, normal, deep, very deep). Three classification models, including K-Nearest Neighbor, Random Forest, and Deep Artificial Neural Network, were used, and their performance was evaluated by calculating accuracy, precision, recall, and F1-score. Results showed that the performance was in the high 50% to early 70% range, with the accuracy of the three classification criteria being about 5% higher than the five criteria. Although the grading criteria and classification model's performance presented in this study are still insufficient, the application of the classification model is possible in predicting the effective soil depth. This study suggests the possibility of predicting more reliable values than the current effective soil depth, which assumes a large area uniformly.

• Journal of the Korean Geotechnical Society
• /
• v.25 no.2
• /
• pp.45-54
• /
• 2009

The electrical characteristics of soils have been used for investigating soil properties. The purpose of this study is the development and application of the electrical resistivity cone probe (ERCP) for the evelation of the porosity in the field with high precision. The shape of the probe tip is a cone shape to minimize the disturbance during penetration. In addition, the four terminal pair configuration is adopted to minimize the electrical interference. The electrical resistances are continuously measured during penetration of the ERCP using penetration rigs with 0.33 mm/sec penetration rate at Incheon and Busan sites. With the measured resistance profile and electrical resisivity of electrolyte of undisturbed samples, soil porosity profiles are obtained by using Archie's law. The empirical coefficients for the Archie's law are obtained based on the electrolyte extracted from the undisturbed samples. The estimated porosity profiles show similar trends to those of in-situ penetration tests such as SPT, CPT, and DMT. This study suggests that the ERCP may be an effective tool for the porosity estimation in the field with minimum disturbance.

• Journal of the Economic Geographical Society of Korea
• /
• v.26 no.1
• /
• pp.1-22
• /
• 2023

This study proposes an integrated use of region and industry as a way to classify firms' innovation activities by type. Existing studies have used the method of determining innovative activities according to the components of the technological regimes and aggregating them by industry classification, but this method cannot fully reflect the heterogeneity within industries in an increasingly sophisticated innovation environment. Therefore, this study divides firms by region and industry and conducts a cluster analysis on the proportion of innovative activities by the components of the technological regimes to derive a total of four innovation types. Using the 2016 Korean Innovation Survey to classify innovation types in the manufacturing industry, we found that innovation activities are concentrated in Seoul, Busan, Incheon, and Chungnam/ Sejong/ Daejeon area, with different deviations by region and industry. The results of the aggregation of industrial innovation activities, weighted by corporate activity by region, show that the level of innovation activity in some manufacturing industries, such as petrochemicals, manufacturing of medical, precision and optical instruments, watches and clocks, is high, but the level of innovation in other sectors within the manufacturing industry is generally low.

• Economic and Environmental Geology
• /
• v.56 no.3
• /
• pp.293-300
• /
• 2023

The Shape Preferred Orientation (SPO) method has been used to analyze the orientation of fault motion, which is utilized as basic data for fault kinematics studies. The rigid grains, which as quartz, feldspar, and rock fragments, in the fault gouge are arranged in the P-shear direction through rigid body rotation by a given shear stress. Using this characteristic, the fault motion can be estimated from the SPO inversely. Recently, a method for securing precision and reliability by measuring 3D-SPO using X-ray CT images and examining the shape of a large number of particles in a short time has been developed. As a result, the SPO method analyzes the orientation of thousands to tens of thousands of particles at high speed, suggests the direction of fault motion, and provides easy accessibility and reliable data. In addition, the shape information and orientation distribution data of particles, which are by-products obtained in the SPO analysis process, are expected to be used as basic data for conducting various studies such as the local deformation of fault rocks and the fault generation mechanism.

• KSCE Journal of Civil and Environmental Engineering Research
• /
• v.29 no.1D
• /
• pp.135-143
• /
• 2009

Integrating the Global Positioning System (GPS) and Inertial Navigation System (INS) sensor technologies using the precise GPS Carrier phase measurements is a methodology that has been widely applied in those application fields requiring accurate and reliable positioning and attitude determination; ranging from 'kinematic geodesy', to mobile mapping and imaging, to precise navigation. However, such integrated system may not fulfil the demanding performance requirements when the baseline length between reference and mobil user GPS receiver is grater than a few tens of kilometers. This is because their positioning/attitude determination is still very dependent on the errors of the GPS observations, so-called "baseline dependent errors". This limitation can be remedied by the integration of GPS and INS sensors, using multiple reference stations. Hence, in order to derive the GPS distance dependent errors, this research proposes measurement processing algorithms for multiple reference stations, such as a reference station ambiguity resolution procedure using linear combination techniques, a error estimation based on Kalman filter and a error interpolation. In addition, all the algorithms are evaluated by processing real observations and results are summarized in this paper.

• Analytical Science and Technology
• /
• v.20 no.4
• /
• pp.347-354
• /
• 2007

A simple and rapid high-performance liquid chromatography assay for the determination of residual novobiocin levels in bovine, porcine, chicken, flatfish and japanese eel muscle has been developed and validated. The separation condition for HPLC/UV was optimized with phenyl hexyl ($4.6{\times}150mm$, $5{\mu}m$) column with 10 mM monobasic sodium phosphate buffer (pH 2.5)/acetonitrile (50/50, v/v) as the mobile phase at a flow rate of 1.0 mL/min and detection wavelength was set at 254 nm. Residues were extracted from tissue by blending with methanol and lipid materials were removed with n-hexane. Then, the methanol extract was evaporated to dryness under a nitrogen stream, reconstituted in the mobile phase. Aliquot of the organic extract was decanted and filtered through $0.45{\mu}m$ syringe filter. The $20{\mu}L$ of the resulting solution was injected into the HPLC system. The calibration ranges were $0.5{\sim}5{\mu}g/g$ and calibration curves were linear with coefficients of correlation better than 0.95. The limits of quantification were $0.5{\mu}g/g$ for all muscles. The recoveries of bovine, porcine, chicken, flatfish and japaneseel muscles were 99.8%, 102.4%, 91.0%, 104.0% and 93.0%, respectively. The procedures were validated according to the CODEX guideline, determining specificity, linearity, accuracy, precision, quantitation limit and recovery.