• Biomolecules & Therapeutics
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• v.21 no.4
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• pp.313-322
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• 2013

Previous studies have demonstrated that repeated administration of the exogenous stress hormone corticosterone (CORT) induces dysregulation in the hypothalamic-pituitary-adrenal (HPA) axis and results in depression and anxiety. The current study sought to verify the impact of catechin (CTN) administration on chronic CORT-induced behavioral alterations using the forced swimming test (FST) and the elevated plus maze (EPM) test. Additionally, the effects of CTN on central noradrenergic systems were examined by observing changes in neuronal tyrosine hydroxylase (TH) immunoreactivity in rat brains. Male rats received 10, 20, or 40 mg/kg CTN (i.p.) 1 h prior to a daily injection of CORT for 21 consecutive days. The activation of the HPA axis in response to the repeated CORT injections was confirmed by measuring serum levels of CORT and the expression of corticotrophin-releasing factor (CRF) in the hypothalamus. Daily CTN administration significantly decreased immobility in the FST, increased open-arm exploration in the EPM test, and significantly blocked increases of TH expression in the locus coeruleus (LC). It also significantly enhanced the total number of line crossing in the open-field test (OFT), while individual differences in locomotor activities between experimental groups were not observed in the OFT. Taken together, these findings indicate that the administration of CTN prior to high-dose exogenous CORT significantly improves helpless behaviors, possibly by modulating the central noradrenergic system in rats. Therefore, CTN may be a useful agent for the treatment or alleviation of the complex symptoms associated with depression and anxiety disorders.

• Health Policy and Management
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• v.30 no.1
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• pp.37-49
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• 2020

Background: Unmet healthcare needs have many advantages for measuring inequalities in healthcare use. However, the existing indicator is difficult to capture the reality of unmet healthcare needs sufficiently and is not quite appropriate in comparing regional inequality. The purpose of this study is to critically analyze the utilization of the unmet healthcare need indicator for regional healthcare inequalities research. Methods: We used the level of healthcare accessibility and healthcare need to categorize the regions that are known to cause differences in healthcare utilization between regions and verified how existing unmet healthcare need indicator is distributed at the regional level. Results: Four types of regions were classified according to the high and low levels of healthcare needs and accessibility. The hypothesis about the regional type expected to have the highest unmet healthcare need was not proved. The hypothesis about the lowest expected regional type was proved, but the difference in the average rate of unmet healthcare needs among regional types was not significant. The standard deviation of the rate of unmet healthcare needs among regions within the same type was also higher than the overall regional variation, which also disproved the whole frame of hypothesis. Conclusion: Failure to prove the hypothesis means the gap between the supposed meaning of the indicator and the reality. In order to understand the current state of healthcare utilization of people in various regions of Korea and to resolve inequality, fundamental research on the in-depth structure and mechanisms of healthcare utilization is needed.

• Transactions of the Korean Society of Automotive Engineers
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• v.19 no.5
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• pp.134-142
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• 2011

Although combustion is essential in most energy generation processes, it is one of the major causes of air pollution. Exhaust pipes with circular fin were designed to study the effect of cooling the recirculated exhaust gases (EGR) of Diesel engines on the chemical composition of the exhaust gases and the reduction in the percentages of pollutant emissions. The gases examined in this study were oxides of nitrogen (NOx), carbon dioxide ($CO_2$) and carbon monoxide (CO). In addition, $O_2$ concentration in the exhaust was measured. The designs adopted in this study were about exhaust pipes with solid and hollow fins around them direct surface force measurement in water using a nano size colloidal probe technique. The direct force measurement between colloidal surfaces has been an essential topic in both theories and applications of surface chemistry. As particle size is decreased from micron size down to true Carbon nano Colloid size (<10 nm), surface forces are increasingly important. Nano particles at close proximity or high solids loading are expected to show a different behavior than what can be estimated from continuum and mean field theories. The current tools for directly measuring interaction forces such as a surface force apparatus or atomic force microscopy (AFM) are limited to particles much larger than nano size. This paper use Water and CNC fluid at normal cooling system of EGR. Experimental result showed all good agreement at Re=$2.54{\times}10^4$ by free convection and Re=$3.36{\times}10^4$ by forced air furnace.

• Journal of the Korean Society for Railway
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• v.15 no.5
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• pp.447-453
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• 2012

It is studied that the structure of the contact plane geometry of the contact wire would be changed when the contact wire tension is increased in the existing overhead contact lines for the purpose of improving the operation speed temporarily. In this paper, the dropper length formula which could be well applied to the pre-sagged catenary is reviewed first. Second, the changing amount of the pre-sag if the contact wire tension change from 20kN to 23kN or from 20kN to 25kN for the Gyeongbu HSL(high speed line) 49.5m catenary is evaluated by using of the self-written program in accordance with the dropper length formula. Moreover, the increasing tension and measuring the pre-sag change experiment in the Gyeongbu 2 HSL was conducted. The calculated data are compared with the measured data. As a result, it is found that the geometry change is very little and will not make the current collection performance deteriorated.

• 한국태양에너지학회:학술대회논문집
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• 2011.11a
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• pp.34-39
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• 2011

Screen printing method is a common way to fabricate the crystalline silicon solar cell with low-cost and high-efficiency. The screen printing metallization use silver paste and aluminum paste for front and rear contact, respectively. Especially the rear contact between aluminum and silicon is important to form the back surface filed (Al-BSF) after firing process. BSF plays an important role to reduces the surface recombination due to $p^+$ doping of back surface. However, Al electrode on back surface leads to bow occurring by differences in coefficient of thermal expansion of the aluminum and silicon. In this paper, we studied the properties of mono crystalline silicon solar cell for rear electrode with aluminum and aluminum-boron in order to characterize bow and BSF of each paste. The 156*156 $m^2$ p-type silicon wafers with $200{\mu}m$ thickness and 0.5-3 ${\Omega}\;cm$ resistivity were used after texturing, diffusion, and antireflection coating. The characteristics of solar cells was obtained by measuring vernier callipers, scanning electron microscope and light current-voltage. Solar cells with aluminum paste on the back surface were achieved with $V_{OC}$ = 0.618V, JSC = 35.49$mA/cm^2$, FF(Fill factor) = 78%, Efficiency = 17.13%.

• Journal of IKEEE
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• v.20 no.3
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• pp.260-264
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• 2016

The MAX77846, which is compatible with MAX77826, is a sub-power management IC (PMIC) for the latest Wearable Watch and 3G/4G smart phones. The MAX77846 contains N-MOSFET (N channel Metal-Oxide Semiconductor Field-Effect Transistor), a high-efficiency regulator, and comparator, etc to power up peripherals. The MAX77846 also provides power on/off control logic for complete flexibility and an $I^2C$ (Inter Integrated Circuit) serial interface to program individual regulator output voltages. In this paper, the simplified power macro-model based on MAX77846 is designed to verify the performance of the battery voltage in terms of current and time, and simulated by using of the LTspice. In addition, it is verified how much time can the charged battery capacity for Samsung Galaxy Gear 2 be used to operate a specified function after measuring the currents flowing to carry out the main functions in real time, which will be applicable to design parameters for the advanced power module

• Journal of The Korean Astronomical Society
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• v.33 no.2
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• pp.89-95
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• 2000

As an efficient method to detect blending of general gravitational microlensing events, it is proposed to measure the shift of source star image centroid caused by microlensing. The conventional method to detect blending by this method is measuring the difference between the positions of the source star image point spread function measured on the images taken before and during the event (the PSF centroid shift, ${\delta}{\theta}$c,PSF). In this paper, we investigate the difference between the centroid positions measured on the reference and the subtracted images obtained by using the difference image analysis method (DIA centroid shift, ${\delta}{\theta}$c.DIA), and evaluate its relative usefulness in detecting blending over the conventional method based on ${\delta}{\theta}$c,PSF measurements. From this investigation, we find that the DIA centroid shift of an event is always larger than the PSF centroid shift. We also find that while ${\delta}{\theta}$c,PSF becomes smaller as the event amplification decreases, ${\delta}{\theta}$c.DIA remains constant regardless of the amplification. In addition, while ${\delta}{\theta}$c,DIA linearly increases with the increasing value of the blended light fraction, ${\delta}{\theta}$c,PSF peaks at a certain value of the blended light fraction and then eventually decreases as the fraction further increases. Therefore, measurements of ${\delta}{\theta}$c,DIA instead of ${\delta}{\theta}$c,PSF will be an even more efficient method to detect the blending effect of especially of highly blended events, for which the uncertainties in the determined time scales are high, as well as of low amplification events, for which the current method is highly inefficient.

• Journal of the Korean Vacuum Society
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• v.18 no.1
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• pp.30-36
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• 2009

The effects of $HfO_2$ film thickness on electrical, optical, and structural properties were investigated. We fabricated ITO/$HfO_2$/ITO metal-insulator- metal (MIM) capacitor using transparent conducting oxide. When $HfO_2$ film thickness increase from 50 nm to 300 nm, dielectric constant of $HfO_2$ was decreased from 20.87 to 9.72. The transparent capacitor shows an overall high performance, such as a dielectric constant about 21 by measuring the ITO/$HfO_2$/ITO capacitor structures and a low leakage current of $2.75{\times}10^{-12}\;A/cm^2$ at +5 V. Transmittance above 80% was observed in visible region.

• Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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• v.21 no.2
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• pp.20-27
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• 2007

[ $SF_6$ ] gas for compacted power facilities has a important role as an insulation gas. It is very blown well that $SF_6$ gas has the superior characteristics as an insulation gas. For reliable operation of SF6-gas-based high and medium voltage equipment it is very important to keep the insulation ability within a safe range. And the experimental and measuring system were implemented. The test chamber designed to endure up to 3 atmospheric pressure. The analysis results of the experimental data shows that positive partial discharge can be detected by discharge current and UHF signal. Additionally it is shown the possibility that $CO_2$ gas sensor of semiconductor type can be detect the variation of $SF_6$ gas condition. The UHF sensor shows good feature to detect the variation of $SF_6$ gas condition for partial discharge and breakdown discharge.

• The Transactions of The Korean Institute of Electrical Engineers
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• v.66 no.2
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• pp.357-362
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• 2017

Among the lithium metal oxides for asymmetric hybrid supercapacitor, $Li_4Ti_5O_{12}(LTO)$ is an emerging electrode material as zero-stain material in volume change during the with the charging and discharging processes. The pulverized LTO powder was observed to show the enhanced capacity from 120 mAh/g to 156 mAh/g at C-rate (10, 100 C). Hybrid supercapacitor module(48V, 416F) was fabricated using an asymmetric hybrid capacitor with a capacitance of 7500F. As a result of the measurement of C-rate characteristics, the module shows that the discharge time is drastically reduced at more than 50C, and the ESR and voltage drop characteristics are increased. The energy density and power density were reduced under high C-rate conditions. When designing asymmetric hybrid supercapacitor module, the C-rate and ESR should be considered As a result of measuring the 5 kw UPS, it was discharged at the current of 116A~170A during the discharge in the voltage range of 48V~30V, and the compensation time at discharge was measured to be about 33.2s. Experimental results show that it can be applied to applications related to stabilization of power quality by applying hybrid supercapacitor module.