• Title/Summary/Keyword: High Throughput Process

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Development of a Reproducibility Index for cDNA Microarray Experiments

  • Kim, Byung-Soo;Rha, Sun-Young
    • Proceedings of the Korean Statistical Society Conference
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    • 2002.05a
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    • pp.79-83
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    • 2002
  • Since its introduction in 1995 by Schena et al. cDNA microarrays have been established as a potential tool for high-throughput analysis which allows the global monitoring of expression levels for thousands of genes simultaneously. One of the characteristics of the cDNA microarray data is that there is inherent noise even after the removal of systematic effects in the experiment. Therefore, replication is crucial to the microarray experiment. The assessment of reproducibility among replicates, however, has drawn little attention. Reproducibility may be assessed with several different endpoints along the process of data reduction of the microarray data. We define the reproducibility to be the degree with which replicate arrays duplicate each other. The aim of this note is to develop a novel measure of reproducibility among replicates in the cDNA microarray experiment based on the unprocessed data. Suppose we have p genes and n replicates in a microarray experiment. We first develop a measure of reproducibility between two replicates and generalize this concept for a measure of reproducibility of one replicate against the remaining n-1 replicates. We used the rank of the outcome variable and employed the concept of a measure of tracking in the blood pressure literature. We applied the reproducibility measure to two sets of microarray experiments in which one experiment was performed in a more homogeneous environment, resulting in validation of this novel method. The operational interpretation of this measure is clearer than Pearson's correlation coefficient which might be used as a crude measure of reproducibility of two replicates.

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A Handover Method Based on the Position Information of a Mobile Terminal (이동 단말기의 위치 정보를 이용한 핸드오버 방법)

  • 이종찬;박상준
    • Journal of the Institute of Electronics Engineers of Korea TC
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    • v.41 no.11
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    • pp.57-66
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    • 2004
  • It is widely accepted that the coverage with high user densities in mobile multimedia environments can only be achieved with small cell such as micro- and pico-cell. The smaller cell size causes frequent handovers between cells and a decrease in the permissible handover processing delay. This may result in the handover failure, in addition to the loss of some packets during the handover. In these cases, re-transmission is needed in order to compensate errors, which triggers a rapid degradation of throughput. In this paper, we propose a new handover scheme in the next generation mobile communication systems, in which the handover setup process is done in advance before a handover request by predicting the handover cell based on mobile terminal's current position and moving direction. Simulation is focused on the handover failure rate and packet loss rate. The simulation results show that our proposed method provides a better performance than the conventional method.

Design and Implementation of a Low-Complexity Real-Time Barrel Distortion Corrector for Wide-Angle Cameras (광각 카메라를 위한 저 복잡도 실시간 베럴 왜곡 보정 프로세서의 설계 및 구현)

  • Jeong, Hui-Seong;Kim, Won-Tae;Lee, Gwang-Ho;Kim, Tae-Hwan
    • Journal of the Institute of Electronics and Information Engineers
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    • v.50 no.6
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    • pp.131-137
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    • 2013
  • The barrel distortion makes serious problems in a wide-angle camera employing a lens of a short focal length. This paper presents a low-complexity hardware architecture for a real-time barrel distortion corrector and its implementation. In the proposed barrel distortion corrector, the conventional algorithm is modified so that the correction is performed incrementally, which results in the reduction of the number of required hardware modules for the distortion correction. The proposed barrel distortion corrector has a pipelined architecture so as to achieve a high-throughput correction. The correction rate is 74.86 frames per sec at the operating frequency of 314MHz in a $0.11{\mu}m$ CMOS process, where the frame size is $2048{\times}2048$. The proposed barrel distortion corrector is implemented with 14.3K logic gates.

$Cu_2ZnSnS_4$ Thin Film Absorber Synthesized by Chemical Bath Deposition for Solar Cell Applications

  • Arepalli, Vinaya Kumar;Kumar, Challa Kiran;Park, Nam-Kyu;Nang, Lam Van;Kim, Eui-Tae
    • Proceedings of the Materials Research Society of Korea Conference
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    • 2011.10a
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    • pp.35.1-35.1
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    • 2011
  • New photovoltaic (PV) materials and manufacturing approaches are needed for meeting the demand for lower-cost solar cells. The prototypal thin-film photovoltaic absorbers (CdTe and $Cu(In,Ga)Se_2$) can achieve solar conversion efficiencies of up to 20% and are now commercially available, but the presence of toxic (Cd,Se) and expensive elemental components (In, Te) is a real issue as the demand for photovoltaics rapidly increases. To overcome these limitations, there has been substantial interest in developing viable alternative materials, such as $Cu_2ZnSnS_4$ (CZTS) is an emerging solar absorber that is structurally similar to CIGS, but contains only earth abundant, non-toxic elements and has a near optimal direct band gap energy of 1.4~1.6 ev and a large absorption coefficient of ${\sim}10^4\;cm^{-1}$. The CZTS absorber layers are grown and investigated by various fabrication methods, such as thermal evaporation, e-beam evaporation with a post sulfurization, sputtering, non-vacuum sol-gel, pulsed laser, spray-pyrolysis method and electrodeposition technique. In the present work, we report an alternative method for large area deposition of CZTS thin films that is potentially high throughput and inexpensive when used to produce monolithically integrated solar panel modules. Specifically, we have developed an aqueous chemical approach based on chemical bath deposition (CBD) with a subsequent sulfurization heat treatment. Samples produced by our method were analyzed by scanning electron microscopy, X-ray diffraction, transmission electron microscopy, absorbance and photoluminescence. The results show that this inexpensive and relatively benign process produces thin films of CZTS exhibiting uniform composition, kesterite crystal structure, and good optical properties. A preliminary solar cell device was fabricated to demonstrate rectifying and photovoltaic behavior.

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Handover in LTE networks with proactive multiple preparation approach and adaptive parameters using fuzzy logic control

  • Hussein, Yaseein Soubhi;Ali, Borhanuddin M;Rasid, Mohd Fadlee A.;Sali, Aduwati
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.9 no.7
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    • pp.2389-2413
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    • 2015
  • High data rates in long-term evolution (LTE) networks can affect the mobility of networks and their performance. The speed and motion of user equipment (UE) can compromise seamless connectivity. However, a proper handover (HO) decision can maintain quality of service (QoS) and increase system throughput. While this may lead to an increase in complexity and operational costs, self-optimization can enhance network performance by improving resource utilization and user experience and by reducing operational and capital expenditure. In this study, we propose the self-optimization of HO parameters based on fuzzy logic control (FLC) and multiple preparation (MP), which we name FuzAMP. Fuzzy logic control can be used to control self-optimized HO parameters, such as the HO margin and time-to-trigger (TTT) based on multiple criteria, viz HO ping pong (HOPP), HO failure (HOF) and UE speeds. A MP approach is adopted to overcome the hard HO (HHO) drawbacks, such as the large delay and unreliable procedures caused by the break-before-make process. The results of this study show that the proposed method significantly reduces HOF, HOPP, and packet loss ratio (PLR) at various UE speeds compared to the HHO and the enhanced weighted performance HO parameter optimization (EWPHPO) algorithms.

Signal Energy-based Cyclostationary Spectrum Sensing for Wireless Sensor Networks (무선센서네트워크를 위한 신호 에너지 기반 사이클로스테이셔너리 스펙트럼 검출)

  • Nguyen, Quoc Kien;Jeon, Taehyun
    • Journal of Satellite, Information and Communications
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    • v.11 no.3
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    • pp.119-122
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    • 2016
  • Feature detection is recognized as an accurate spectrum sensing approach when the information of the desired signal is partly known at the receiver. This type of detection was proposed to overcome large noise environment. Cyclostationary detection is an example of feature detection in spectrum sensing technique in cognitive radio. However, the cyclostationary process calculation requires a lot of processing time and information about the designed signals. On the other hand, energy detection spectrum sensing is widely known as a simple and compact spectrum sensing technique. However, energy detection is highly affected by large noise and lead to high detection error probability. In this paper, the combination of energy detection and cyclostationary is proposed in order to increase the accuracy and decrease the calculation and processing time. The two-layer threshold is utilized in order to reduce the complexity of computation and processing time in cyclostationary which can lead to the improved throughput of the system. The simulation result shows that the implementation of energy-based cyclostationary detector can help to improve the performance of the system while it can considerably reduce the required time for signal detection.

Optimization of Expression Conditions for Soluble Protein by Using a Robotic System of Multi-culture Vessels

  • Ahn, Woo-Sung;Ahn, Ji-Young;Jung, Chan-Hun;Hwang, Kwang-Yeon;Kim, Eunice Eun-Kyeong;Kim, Joon;Im, Ha-Na;Kim, Jin-Oh;Yu, Myeong-Hee;Lee, Cheol-Ju
    • Journal of Microbiology and Biotechnology
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    • v.17 no.11
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    • pp.1868-1874
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    • 2007
  • We have developed a robotic system for an automated parallel cell cultivation process that enables screening of induction parameters for the soluble expression of recombinant protein. The system is designed for parallelized and simultaneous cultivation of up to 24 different types of cells or a single type of cell at 24 different conditions. Twenty-four culture vessels of about 200 ml are arranged in four columns${\times}$six rows. The system is equipped with four independent thermostated waterbaths, each of which accommodates six culture vessels. A two-channel liquid handler is attached in order to distribute medium from the reservoir to the culture vessels, to transfer seed or other reagents, and to take an aliquot from the growing cells. Cells in each vessel are agitated and aerated by sparging filtered air. We tested the system by growing Escherichia coli BL21(DE3) cells harboring a plasmid for a model protein, and used it in optimizing protein expression conditions by varying the induction temperature and the inducer concentration. The results revealed the usefulness of our custom-made cell cultivation robot in screening optimal conditions for the expression of soluble proteins.

Big Data Processing Scheme of Distribution Environment (분산환경에서 빅 데이터 처리 기법)

  • Jeong, Yoon-Su;Han, Kun-Hee
    • Journal of Digital Convergence
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    • v.12 no.6
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    • pp.311-316
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    • 2014
  • Social network server due to the popularity of smart phones, and data stored in a big usable access data services are increasing. Big Data Big Data processing technology is one of the most important technologies in the service, but a solution to this minor security state. In this paper, the data services provided by the big -sized data is distributed using a double hash user to easily access to data of multiple distributed hash chain based data processing technique is proposed. The proposed method is a kind of big data data, a function, characteristics of the hash chain tied to a high-throughput data are supported. Further, the token and the data node to an eavesdropper that occurs when the security vulnerability to the data attribute information to the connection information by utilizing hash chain of big data access control in a distributed processing.

New Pipeline Architecture for Low Power FIR Filter (저전력 FIR 필터를 위한 새로운 파이프라인 아키텍쳐)

  • Paik, Woo-Hyun;Ki, Hoon-Jae;Yoo, Jang-Sik;Lee, Sang-Won;Kim, Soo-Won
    • Journal of the Korean Institute of Telematics and Electronics D
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    • v.36D no.1
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    • pp.63-73
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    • 1999
  • This paper presents new pipeline architecure for low power and high speed digital FIR filters. The proposed architecture based on retiming technique achieves enhancement on speed by sharing the input delay stage with multiplication of input data and on power combined with supply voltage scaling down technique. An 8-tap digital FIR filter for PRML disk-drive read channels adopting the proposed pipeline architecture has been designed and fabricated with 0.8${\mu}m$ CMOS double metal process technology. Measured results show that the designed FIR filter operates to 192 MHz in average and dissipates 1.22 mW/MHz at 3.3.V power supply. As a result, the proposed architecture improves speed by about 16% and reduces power dissipation by about 23% when operating at the same throughput.

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An Improved EPS Handover Scheme for Seamless D2D Communications (끊김없는 D2D 통신을 위한 EPS 핸드오버 개선 방안)

  • Kim, Jong-Chan;Min, Sang-Won
    • The Journal of The Korea Institute of Intelligent Transport Systems
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    • v.17 no.4
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    • pp.168-180
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    • 2018
  • Due to the spread of mobile devices and the introduction of high-quality services, mobile traffic is expected to increase sharply and overload of cellular networks is expected. D2D communication is a way to reduce the load and evolve to 5th generation. Since D2D communication directly communicates between the terminals, it can reduce the overload of the cellular network and improve energy efficiency, data rate and network performance. This paper proposes a D2D handover scheme for D2D communication in cellular networks. The cellular network is a 3GPP EPS, and the proposed D2D handover method improves the existing EPS handover process considering compatibility between existing EPS and D2D communication. We also demonstrate the superiority of the proposed handover scheme using the network simulator ns-3. Simulation results show that the proposed handover scheme is superior to existing handover methods in terms of CUE variation, packet transmission delay time, and throughput.