• Proceedings of the Korean Operations and Management Science Society Conference
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• 2005.10a
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• pp.321-333
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• 2005

With the limited frequency spectrum and an increasing demand for cellular communication services, the problem of channel assignment becomes increasingly important. However, finding a conflict free channel assignment with the minimum channel span is NP hard. As demand for services has expanded in the cellular segment, sever innovations have been made in order to increase the utilization of bandwidth. The innovations are cellular concept, dynamic channel assignment and hierarchical network design. Hierarchical network design holds the public eye because of increasing demand and quality of service to mobile users. We consider the frequency assignment problem and the base station placement simultaneously. Our model takes the candidate locations emanating from this process and the cost of assigning a frequency, operating and maintaining equipment as an input. In addition, we know the avenue and demand as an assumption. We propose the network about the profit maximization. This study can apply to GSM(Global System for Mobile Communication) which has 70% portion in the world. Hierarchical network design using GA(Genetic Algorithm) is the first three-tier (Macro, Micro, Pico) model, We increase the reality through applying to EMC (Electromagnetic Compatibility Constraints). Computational experiments on 72 problem instances which have 15${\sim}$40 candidate locations demonstrate the computational viability of our procedure. The result of experiments increases the reality and covers more than 90% of the demand.

• Journal of Institute of Control, Robotics and Systems
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• v.11 no.10
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• pp.843-850
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• 2005

FBA(flux balance analysis) with Boolean rules for representing regulatory events has correctly predicted cellular behaviors, such as optimal flux distribution, maximal growth rate, metabolic by-product, and substrate concentration changes, with various environmental conditions. However, until now, since FBA has not taken into account a hierarchical regulatory network, it has limited the representation of the whole transcriptional regulation mechanism and interactions between specific regulatory proteins and genes. In this paper, in order to solve these problems, we describe the construction of hierarchical regulatory network with defined symbols and the introduction of a weight for representing interactions between symbols. Finally, the whole cellular behaviors with time were simulated through the linkage of a hierarchical regulatory network module and dynamic simulation module including FBA. The central metabolic network of E. coli was chosen as the basic model to identify our suggested modeling method.

• Journal of the military operations research society of Korea
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• v.34 no.2
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• pp.63-77
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• 2008

With the limited frequency spectrum and an increasing demand for cellular communication services, the problem of channel assignment becomes increasingly important. However, finding a conflict free channel assignment with the minimum channel span is NP hard. The innovations are cellular concept, dynamic channel assignment and hierarchical network design. We consider the frequency assignment problem and the base station placement simultaneously. Our model takes the candidate locations emanating from this process and the cost of assigning a frequency, operating and maintaining equipment as an input. Hierarchical network design using genetic algorithm is the first three-tier (Macro, Micro, Pico) model. We increase the reality through applying to Electromagnetic Compatibility Constraints. Computational experiments on 72 problem instances which have $15{\sim}40$ candidate locations demonstrate the computational viability of our procedure. The result of experiments increases the reality and covers 90% of the demand.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.31 no.1B
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• pp.1-8
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• 2006

Currently, there are many efforts underway to provide Internet service on integrated wireless and wired networks. Supporting IP mobility is one of the major issues to construct IP based wireless network. Mobile IP has been proposed to solve the IP Mobility problem. But, in processing frequent handoffs in cellular based wireless access network, Micro mobility protocols have been proposed to solve these problems. Micro mobility protocols proposed the Cellular IP, HAWII, and Hierarchical Mobile IP. Cellular IP attracts special attention for it's seamless mobility support in limited geographical areas. New BS must be known to occur begging of handoff in Cellular IP indirect handoff. Therefore during perceiving of hanoff, packet loss or packet duplication still can occur in Cellular IP indirect handoff, which results in the degradation of UDP and TCP performance. In this paper, we propose a enhanced indirect handoff scheme for Cellular IP. Proposed handoff scheme is using a crossover node to minimize the signalling procedure and using a buffering to minimize the packet loss or packet duplication.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.13 no.5
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• pp.2243-2257
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• 2019

A heterogeneous cellular network (HCN) is useful to increase the spectral and energy efficiency of wireless networks and to reduce the traffic load from the macro cell. The performance of the secondary user equipment (SUE) is affected by interference from the eNodeB (eNB) in a macro cell. To decrease the interference between the macro cell and the small cell, allocating resources properly is essential to an HCN. This study considers the scenario of a software-defined heterogeneous cellular network and performs the resource allocation process. First, we show the system model of HCN and formulate the optimization problem. The optimization problem is a complex process including power and frequency resource allocation, which imposes an extremely high complexity to the HCN. Therefore, a hierarchical resource allocation scheme is proposed, which including subchannel selection and a particle swarm optimization (PSO)-based power allocation algorithm. Simulation results show that the proposed hierarchical scheme is effective in improving the system capacity and energy efficiency.

• Bioinformatics and Biosystems
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• v.2 no.2
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• pp.71-74
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• 2007

Cell phenotypes are determined by groups of functionally related genes. Microarray profiling of gene expression provides us response of cellular state to its perturbation. Several methods for uncovering a cellular network show reliable network reconstruction. In this study, we present reconstruction of genetic regulatory network of inflammation bowel disease in human peripheral blood mononuclear cell. The microarray based on Affymetrix Gene Chip Human Genome U133 Array Set HG-U133A is processed and applied network reconstruction algorithm, ARACNe. As a result, we will show that inferred network composed of 450 nodes and 2017 edges is roughly scale-free network and hierarchical organization. The major hub, CCNL2 (cyclin A2), in inferred network is shown to be associated with inflammatory function as well as apoptotic function.

• Journal of Microbiology and Biotechnology
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• v.15 no.3
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• pp.551-559
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• 2005

The recent rapid increase in genomic data related to many microorganisms and the development of computational tools to accurately analyze large amounts of data have enabled us to design several kinds of simulation approaches for the complex behaviors of cells. Among these approaches, dFBA (dynamic flux balance analysis), which utilizes FBA, differential equations, and regulatory events, has correctly predicted cellular behaviors under given environmental conditions. However, until now, dFBA has centered on substrate concentration, cell growth, and gene on/off, but a detailed hierarchical structure of a regulatory network has not been taken into account. The use of Boolean rules for regulatory events in dFBA has limited the representation of interactions between specific regulatory proteins and genes and the whole transcriptional regulation mechanism with environmental change. In this paper, we adopted the operon as the basic structure, constructed a hierarchical structure for a regulatory network with defined fundamental symbols, and introduced a weight between symbols in order to solve the above problems. Finally, the total control mechanism of regulatory elements (operons, genes, effectors, etc.) with time was simulated through the linkage of dFBA with regulatory network modeling. The lac operon, trp operon, and tna operon in the central metabolic network of E. coli were chosen as the basic models for control patterns. The suggested modeling method in this study can be adopted as a basic framework to describe other transcriptional regulations, and provide biologists and engineers with useful information on transcriptional regulation mechanisms under extracellular environmental change.

• Proceedings of the Korea Information Processing Society Conference
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• 2004.05a
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• pp.1401-1404
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• 2004

점증하고 있는 무선망에서의 다양한 멀티미디어 서비스를 안정적으로 지원하기 위해서는 효율적인 대역폭 관리가 필수적이다. 본 논문에서는 차세대 네트워크의 기반이 되는 계층 셀 구조에서, 대역폭의 효율적인 관리를 지원하기 위한 통합 프레임워크를 제안하였다. 현재 트래픽의 과밀도와 사용자의 이동성을 기반으로 적절한 셀 선택, 대역폭 예약 및 재설정, 버퍼링 등의 알고리즘을 설계하였으며, 이들을 유기적으로 통합, 시스템 전반의 QoS를 향상시켰다.

• Proceedings of the Korean Society for Bioinformatics Conference
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• 2004.11a
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• pp.39-49
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• 2004

When there is a lack of detailed kinetic information, dFBA(dynamic flux balance analysis) has correctly predicted cellular behavior under given environmental conditions with FBA and different ial equations. However, until now, dFBA has centered on substrate concentration, cell growth, and gene on/off, but a detailed hierarchical structure of a regulatory network has not been taken into account. For this reason, the dFBA has limited the represen tation of interactions between specific regulatory proteins and genes and the whole transcriptional regulation mechanism with environmental change. Moreover, to calculate optimal metabolic flux distribution which maximizes the growth flux and predict the b ehavior of cell system, linear programming package(LINDO) and spreadsheet package(EXCEL) have been used simultaneously. thses two software package have limited in the visual representation of simulation results and it can be difficult for a user to look at the effects of changing inputs to the models. Here, we descirbes the construction of hierarchical regulatory network with defined symbolsand the development of an integrated system that can predict the total control mechanism of regulatory elements (opero ns, genes, effectors, etc.), substrate concentration, growth rate, and optimal flux distribution with time. All programming procedures were accoplished in a visual programming environment (LabVIEW).

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.9 no.1
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• pp.1-19
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• 2015

With the recent popularity of smart terminals, the demand for high-data-rate transmission is growing rapidly, which brings a new challenge for the traditional cellular networks. Both device-to-device (D2D) communication and small cells are effective to improve the transmission efficiency of local communication. In this paper, we apply D2D communication into a small cell network system (SNets) and study about the optimization problem of resource allocation for D2D communication. The optimization problem includes system scheduling and resource allocation, which is exponentially complex and the optimal solution is infeasible to achieve. Therefore, in this paper, the optimization problem is decomposed into several smaller problems and a hierarchical scheme is proposed to obtain the solution. The proposed hierarchical scheme consists of three steps: D2D communication groups formation, the estimation of sub-channels needed by each D2D communication group and specific resource allocation. From numerical simulation results, we find that the proposed resource allocation scheme is effective in improving the spectral efficiency and reducing the outage probability of D2D communication.