• Asian-Australasian Journal of Animal Sciences
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• v.31 no.1
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• pp.149-156
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• 2018

Objective: Broilers show clear preference towards red color light (RL). However setting of an optimum light intensity is difficult since dim intensities that favor growth reduce welfare. This experiment was conducted to test the most effective RL intensity regimen (Dim [5 lux; DI] vs high [320 lux; HI]) in combination applied at different growth stages that favors for both performance and welfare. Methods: Complete randomize design was adopted with 6 replicates. Treatments were; T1 = early DI (8-21 d)+latter HI (22-35 d); T2 = early DI (8-28 d)+latter HI (29-35 d), T3 = early HI (8-21 d)+latter DI (22-35 d), T4 = early HI (8-28 d)+latter DI (29-35 d) and T5 = control (white light; WT) (8-35 d) at medium intensity (20 lux). Body weight (BW), weight gain (WG), water/feed intake and ratio, feed conversion ratios (FCR) were assessed. Common behaviours (15) were recorded by scan sampling method. Lameness, foot pad dermatitis, breast blisters, hock burning damage were assessed as welfare parameters. Fear reactions were tested using Tonic Immobility Test. Ocular and carcass evaluations were done. Meat and tibiae were analyzed for fat and bone ash respectively. Results: On 35 d, the highest BW ($2,155.72{\pm}176g$), WG ($1,967.78{\pm}174g$) were recorded by T2 compared to WT ($BW_{WT}=1,878.22{\pm}155$, $WG_{WT}=1,691.83{\pm}160$). But, application of RL, either DI, or HI during early/latter stage had no significant effect on FCR. Under HI, birds showed much higher active behaviours. DI encourages eating. Though LI changed from DI to HI, same trend could be seen even under HI. The highest leg strength ($218.5{\pm}120s$) was recorded by T2. The lowest leg strength ($64.58{\pm}33s$) and the highest ocular weight ($2.48{\pm}1g$) were recorded by T1. Significantly (p<0.05) the highest skin weight ($162.17{\pm}6g$) but the lowest fat% in meat ($13.03%{\pm}5%$) was recorded by T2. Conclusion: Early exposure to DI-RL up to 28 days followed by exposure to HI-RL is the most favorable lighting regimen for optimizing production, better welfare of broilers and improving health benefits of meat.

• Journal of Haehwa Medicine
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• v.18 no.2
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• pp.37-45
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• 2009

In early 1970s, Electronic Manometers were researched and developed for modernization and objectification of pulse diagnosis. Method of finger pressing, also known as cuffs pressing, is essential for sensing a pulse wave. I think comprehension and deduction of problem from the existing Hi-soo type electronic manometer, will be important for making a better one. The Hi-soo type electronic manometer is constructed of cuff pressing type sensor, differential amplifier, transmitter and recorder. Pulse movement and pulse wave, gauging blood flow, is analyzed by pulse image of "Yixuerumen(醫學入門)". At standard of pulse wave, huanmai(緩脈) is distinguish from chishu(slow and fast, 遲數), fushen(float and sink, 浮沈), interference wave, modificated wave, and phase angel. The Hi-soo type electronic manometer had no explanation of formational mechanism, significantly different with pulse wave which is early known and reported. The strength of Hi-soo type electric manometer is use of cuff pressing type sensor. Above all, the importance of electric manometer is reading the pulse movement accurately then expressing it as pulse wave. From now on the improvement of precise sensor should make a progress.

• Journal of The Korean Society of Grassland and Forage Science
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• v.38 no.1
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• pp.16-22
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• 2018

Oats (Avena sativa L.), which are known as one of the forage crops of Korea, have good livestock palatability and are popular to cattle farmers because of their high dry matter. However, the cultivation of double cropping in the rice field was reluctant due to the late maturing for farmers to plant rice continuously. 'Hi-early', a winter oats for forage use, was developed by the breeding team at National Institute of Crop Science, RDA in 2016. It was derived from a cross between '517A2-121'(IT133383) and 'CI7604' (IT133379). Subsequent generations followed by the cross were handled in bulk and pedigree selection programs at Suwon, Iksan and Jeonju, respectively. After preliminary and advance yield test for 2 years, 'SO2004015-B-B-23-1-3-7', designated as a line name of 'Gwiri92', were subsequently evaluated for earliness and forage yield during 3 years in four parts such as Jeju (upland), Yesan (upland), Iksan (upland), and Jeonju (paddy), from 2014 to 2016, and finally named as 'Hi-early'. Cultivar 'Hi-early' has the characteristics of medium leaves of green color, thick diameter culm, and medium grain of brown color. Over 3 years, the heading date of 'Hi-early' was about 9 days earlier than that of check cultivar 'Samhan' (April 26 and May 5, respectively). Average forage fresh yield of 'Hi-early' harvested at milk-ripe stage was similar to check cultivar ($40.2tone\;ha^{-1}$ and 40.0 tone ha-1, respectively), and dry matter yield also was similar to check cultivar (14.2 tone ha-1 and $14.0tone\;ha^{-1}$, respectively). Cultivar 'Hi-early' was lower than the check cultivar 'Samhan' in terms of the protein content (6.2% and 7.0%, respectively) and total digestible nutrients (61.0%, and 62.5%, respectively), while the TDN yield was more than the check ($7.91tone\;ha^{-1}$ and $7.64tone\;ha^{-1}$, respectively). Fall sowing cropping of 'Hi-early' is recommended only in areas where average daily minimum mean temperatures in January are higher than $-6^{\circ}C$, and it should not be cultivated in mountain areas, where frost damage is likely to occur.

• Proceedings of the Korean Geotechical Society Conference
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• 2010.09a
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• pp.664-675
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• 2010

Recently environment-friendly construction method is major trend in both domestic and world constrction fields. In this paper High Functional Performance Agent(Hi-FA) which has various improved engineering characteristics different with conventional Portland cement grouting, such as high viscosity, liquidity, void filling ability, early hardening, and separation resistance, was analyzed by field and laboratory test. Also soil improvement and existing deep foundation protection works were performed and analyzed using Hi-FA.

• The Bulletin of The Korean Astronomical Society
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• v.44 no.1
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• pp.75.3-75.3
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• 2019

Understanding how ram pressure stripping (RPS) affects the star formation activity of cluster galaxies is one of the important issues in astrophysics. To examine whether we can identify any discernible trend in the star formation activity of galaxies undergoing ram pressure stripping, we study the star formation properties of galaxies in the Virgo cluster for which high-resolution HI images are available. We first classify galaxies in the Extended Virgo Cluster Catalog into different stages of RPS based on their HI morphology, HI deficiency, and location in phase space. We then examine various star formation activity indicators of these galaxies, which include starburstiness, g - r color, and WISE [3.4]-[12] color. No noticeable enhancement in star formation was identified for galaxies undergoing early or active stripping. Our results suggest that star formation activity at best seems to be enhanced locally in such galaxies, making it challenging to detect with integrated photometry. With the combination of HI deficiencies and locations in phase space, we were instead able to capture the overall quenching of star formation activity with increasing degree of ram pressure stripping, which agree with previous studies.

• Journal of Digital Contents Society
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• v.10 no.1
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• pp.159-168
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• 2009

Recently, the mobile retention and use rates for the children are increasing. And early-childhood english education is all the rage. Thus, we propose a mobile contents for studying english stories of children. The proposed content provides children with studying english via a mobile phone in anywhere, anytime. We call the proposed contents "ShK". ShK is an abbreviation for "Say, hi Kids!". ShK induces a motive and interest about studying through a storytelling and avatars. And parents of students can manage studying contents of children through a private web site. Thus, "Say, hi Kids!" will became the epochal ubiquitous english educational contents for children.

• Journal of Microbiology
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• v.33 no.4
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• pp.339-343
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• 1995

We isolated a 10 kb Bam HI fragment originated from the chromosome of a $H_2O$$^2$-resistant mutant strain of Streptomyces coelicolor, which confer $H_2O$$^2$-resistance to S. lividance upon transformation. Among various subclones ot 10kb Bam HI fragment tested for their $H_2O$$^2$-resistant phenotype in S. lividans, a subclone containing 5.2 kb Bam HI-BglII fragment was found to be responsible for $H_2O$$^2$-resistance. The plasmid containing this 5.2 kb fragment was then transformed into S. coellicolor A3(2) at early and tested for their phenotype of $H_2O$$^2$-resistance and the change in various enzymes whose activity can be stained in the gel. We found out that the 5.2 kb insert DNA conferred $H_2O$$^2$-resisstance in S. coelicolor A3(2) at early phase of cell growth. The presence of this DNA also resulted in higher level of peroxidase compared with the wild type cell containing parental vector (pIJ702) only. Esterase activity was also higher in this clone. However, alcohol dehydrogenase activity decreased compared with the wild type. These results suggest that the presence of a gene in 5.2 kb BamHI-BglII DNA fragment causes multiple changes in S. coelicolor related to its response against hydrogen peroxide. The result also implies that not only peroxidase but also esterase may function in the defencse meahsnism agianst $H_2O$$^2$-.

• Journal of the Ergonomics Society of Korea
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• v.11 no.1
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• pp.67-79
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• 1992

Cardiac systolic time intervals (STLs) and Heather index (HI) were used to access changes in left ventricular function of six male subjects exposed to postural changes,$0^{\circ}C$, ${\pm}2^{\circ}C$, ${\pm}45^{\circ}C$, ${\pm}90^{\circ}C$, Significant prolongation of the pre-ejection period (PEP) and PEP/ LVET ratio, shortening of the left ventricular ejection time (LVET), STI, HI and $1/PEP^{2}$were observed during exposure to both $+45^{\circ}C $ and $+90^{\circ}C $But the values measured during $-45^{\circ}C $ and$-90^{\circ}C $ were reversed. Changes in fluid shift, filling volume, preload, after load and sympathetic activities may account for the observed findings. Early response of cardiac foctions was recorded using impedance cardiography. This method is very simple but accurate. Thus it will be useful in this aerospace and work physiology. In conclusion, STIs appear to provide reliable noninvasive method for examining changes of cardiac function during exposure to postural changes.

• The Bulletin of The Korean Astronomical Society
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• v.46 no.2
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• pp.41.1-41.1
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• 2021

Neutral (HI) gas clouds associated with galaxies are responsible for fuelling the star-formation in the universe. In literature, the extremely strong damped Lyman-alpha absorbers (or ESDLAs) have been known to be sensitive to the effects of HI-H2 transition and star-formation in galaxies. Yet, ESDLAs are rare to probe due to the smaller cross section they subtend on the sky (similar to galaxies). In my talk, I will focus primarily on my study of the nature of ESDLAs that are observed as absorption signature along the line-of-sight (LOS) of a quasar (QSO). I will further look at the HI-H2 transition and interesting results relevant to diffuse molecular gas and the multi-phase medium (gas in different ionization states) that are associated with ESDLAs. Furthermore, I will also discuss how the ESDLA environments differ from the high star-forming and molecular environments detected in blind optical and radio surveys consecutively.

• International Journal of Stem Cells
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• v.16 no.3
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• pp.281-292
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• 2023

Background and Objectives: Human induced pluripotent stem cell (hiPSC)-derived cardiomyocyte (CM) hold great promise as a cellular source of CM for cardiac function restoration in ischemic heart disease. However, the use of animal-derived xenogeneic substances during the biomanufacturing of hiPSC-CM can induce inadvertent immune responses or chronic inflammation, followed by tumorigenicity. In this study, we aimed to reveal the effects of xenogeneic substances on the functional properties and potential immunogenicity of hiPSC-CM during differentiation, demonstrating the quality and safety of hiPSC-based cell therapy. Methods and Results: We successfully generated hiPSC-CM in the presence and absence of xenogeneic substances (xeno-containing (XC) and xeno-free (XF) conditions, respectively), and compared their characteristics, including the contractile functions and glycan profiles. Compared to XC-hiPSC-CM, XF-hiPSC-CM showed early onset of myocyte contractile beating and maturation, with a high expression of cardiac lineage-specific genes (ACTC1, TNNT2, and RYR2) by using MEA and RT-qPCR. We quantified N-glycolylneuraminic acid (Neu5Gc), a xenogeneic sialic acid, in hiPSC-CM using an indirect enzyme-linked immunosorbent assay and liquid chromatography-multiple reaction monitoring-mass spectrometry. Neu5Gc was incorporated into the glycans of hiPSC-CM during xeno-containing differentiation, whereas it was barely detected in XF-hiPSC-CM. Conclusions: To the best of our knowledge, this is the first study to show that the electrophysiological function and glycan profiles of hiPSC-CM can be affected by the presence of xenogeneic substances during their differentiation and maturation. To ensure quality control and safety in hiPSC-based cell therapy, xenogeneic substances should be excluded from the biomanufacturing process.