• 한국시뮬레이션학회논문지
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• 제12권4호
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• pp.25-40
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• 2003

With the growing usage of the networks, the world-wide Internet has become the main means to exchange data and carry out transactions. It has also become the main means to attack hosts. To solve the security problems which occur in the network such as Internet, we import software products of network security elements like an IDS (Intrusion Detection System) and a firewall. In this paper, we have designed and constructed the general simulation environment of network security model composed of multiple IDSes and a firewall which coordinate by CNP (Contract Net Protocol) for the effective detection of the intrusion. The CNP, the methodology for efficient integration of computer systems on heterogeneous environment such as distributed systems, is essentially a collection of agents, which cooperate to resolve a problem. Command console in the CNP is a manager who controls the execution of agents or a contractee, who performs intrusion detection. In the network security model, each model of simulation environment is hierarchically designed by DEVS(Discrete Event system Specification) formalism. The purpose of this simulation is that the application of rete pattern-matching algorithm speeds up the inference cycle phases of the intrusion detection expert system and we evaluate the characteristics and performance of CNP architecture with rete pattern-matching algorithm.

• East Asian Economic Review
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• 제21권1호
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• pp.3-27
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• 2017

This paper studied the effects of anti-dumping measures on the imports to investigate whether the trade restriction effect of an anti-dumping duty is dominant. Our results indicate that a 1% increase in the anti-dumping duties decreases the import of the targeted product by about 0.43~0.51%. The actual statistics, however, show that the total import of the targeted products increased by about 30 percent while an anti-dumping duty was in force. That indicates that an anti-dumping duty is just a temporary import relief. This paper also investigated whether an anti-dumping duty is terminated in the case that the injury would not be likely to continue or recur if the duty were removed. The hazards model estimates show that increase in market share, MFN tariff rate, and dumping margin decrease the hazard of termination of an anti-dumping duty, but the increase in value added increases the hazard of termination. Generally speaking, this result indicates that the WTO member countries have regulated the overuse of an anti-dumping measure. The findings of this paper show that there is a country- and industry-wise heterogeneous characteristic in the effect as well as termination of an anti-dumping duty.

• 한국산학기술학회:학술대회논문집
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• 한국산학기술학회 2003년도 Proceeding
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• pp.197-206
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• 2003

With the growing usage of the networks, the world-wide Internet has become the main means to exchange data and carry out transactions. It has also become the main means to attack hosts. To solve the security problems which occur in the network such as Internet, we import software products of network security elements like an IDS (Intrusion Detection System) and a firewall. In this paper, we have designed and constructed the General Simulation Environment of Network Security model composed of multiple IDSes and a firewall which coordinate by CNP (Contract Net Protocol) for the effective detection of the intrusion. The CNP, the methodology for efficient integration of computer systems on heterogeneous environment such as distributed systems, is essentially a collection of agents, which cooperate to resolve a problem. Command console in the CNP is a manager who controls tie execution of agents or a contractee, who performs intrusion detection. In the Network Security model, each model of simulation environment is hierarchically designed by DEVS (Discrete EVent system Specification) formalism. The purpose of this simulation is to evaluate the characteristics and performance of CNP architecture with rete pattern matching algorithm and the application of rete pattern matching algorithm for the speeding up the inference cycle phases of the intrusion detection expert system.

• Natural Product Sciences
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• 제27권3호
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• pp.208-215
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• 2021

𝛽-Patchoulene (𝛽-PAE) is a tricyclic sesquiterpene which performed many potential bioactivities and can be found in patchouli oil but in very low concentration. This study aimed to obtained 𝛽-PAE in high concentration by conversion of patchouli alcohol (PA) in patchouli oil under acid catalyzed reaction. Patchouli oil was fractinated by vacuum distillation at 96 kPa to get the fraction with the highest PA content. H₂SO₄ and ZnCl₂ were used respectively as homogeneous and heterogeneous acid catalysts in the conversion reaction of the selected fraction. Patchouli oil, the fractions and the products were analysed by using GC-MS and FTIR instruments. Moreover, the interaction of 𝛽-PAE to COX-2 protein was studied to understand the antiinflammation activity of 𝛽-PAE. The results showed that patchouli oil contains 25.3% of PA. The selected fraction which has the highest PA content (70.3%) was distilled at 151 - 152 ℃. The application of ZnCl₂ catalyst in conversion reaction did not succeed. In contrast, H₂SO₄ as a catalyst in acetic acid solvent succeeded in converting the overall fraction of PA to 𝛽-PAE. Furthermore, the molecular docking study of 𝛽-PAE against COX-2 enzyme showed van der Waals and alkyl-alkyl stacking interactions on ten amino acid residues.

• 한국군사과학기술학회지
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• 제24권3호
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• pp.272-280
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• 2021

We research and develop a SW-based virtual testing product that can be commonly used in the design/development of non-communication EW systems before the production of physical test products. Through this study, we have developed M&S technology to improve the accuracy of EW weapon system analysis/design and to verify and predict the performance of EW equipment, and to develop proven engineering module models and model base systems. It proposes a technology to build an EW M&S framework that can flexibly link/integrate various engineering/engage-level EW heterogeneous M&S systems.

• 패션비즈니스
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• 제26권4호
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• pp.136-153
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• 2022

The fashion industry is considered hazardous and a threatened to the environment. Due the negative perception, the industry should focus on sustainability as a social role. Therefore, several redesign fashion collaborations mainly focusing on renewing abandoned resources are already in place. The research method was based on previous studies, and 3 characteristics were derived: Redesign collaboration between fashion companies, Redesign collaboration between fashion & heterogeneous industries, and Redesign collaboration between the fashion industry & non-profit organizations. Those 3 characteristics were reviewed using 4 criteria. First, to establish and maximize the sustainable brand image and to be the best examples in environmental management, the organization endeavors to collaborate with various industries, institutions, and designers. Second is the expansion of the customer network through the spread of value consumption. Third is the creation of new values through a resource circulation structure. This means that the resource circulation structure system helps the partners to minimize on wastage. Fourth is the spread of de-boundary lines and the possibility of brand growth. Through collaboration with other industries, the boundaries of materials used in the fashion industry started to blur, thus expanding the continuous brand growth potential. The study derived the characteristics of redesign collaboration by systematically analyzing the cases. Further, the study looks forward to analyzing the characteristics of the products processed by redesign fashion collaborations in future research.

• Geomechanics and Engineering
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• 제33권4호
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• pp.401-414
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• 2023

Organic clays are ideal habitat for flora and fauna. From a geotechnical perspective, organic clays are soft, weak, variable, heterogeneous and flocculated. Portland cement is a universally common stabiliser. However, some organic acids in soil inhibit full hydration and expose cementation products to rapid dissolution. This paper investigates scopes for use of C₃S cement to enable durable cementation. Prospects of using PP fibre alongside with C₃S cement, scopes for partial replacement of C₃S cement with a plant-based nanosilica and evolution of binders are then investigated. Binding mixtures here mimic the natural functions of rhizoliths, amorphous phases, and calcites. Testing sample population include natural and fibre-reinforced clays, compact mixes of clay - C₃S cement, clay - nanobiosilica, and clay, C₃S cement and nanobiosilica. Benefits and constraints of C₃S cement and fibres for retaining the naturally flocculated structure of organic clays are discussed. Nanobiosilica provides an opportunity to cut the C₃S content, and to transition of highly compressive organic clays into an engineered, open-structured medium with >0.5 MPa compressive strength across the strains spanning from peak to 1.5-times peak.

• BMB Reports
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• 제57권6호
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• pp.263-272
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• 2024

Amyloid-β (Aβ) is one of the amyloidogenic intrinsically disordered proteins (IDPs) that self-assemble to protein aggregates, incurring cell malfunction and cytotoxicity. While Aβ has been known to regulate multiple physiological functions, such as enhancing synaptic functions, aiding in the recovery of the blood-brain barrier/brain injury, and exhibiting tumor suppression/antimicrobial activities, the hydrophobicity of the primary structure promotes pathological aggregations that are closely associated with the onset of Alzheimer's disease (AD). Aβ proteins consist of multiple isoforms with 37-43 amino acid residues that are produced by the cleavage of amyloid-β precursor protein (APP). The hydrolytic products of APP are secreted to the extracellular regions of neuronal cells. Aβ 1-42 (Aβ42) and Aβ 1-40 (Aβ40) are dominant isoforms whose significance in AD pathogenesis has been highlighted in numerous studies to understand the molecular mechanism and develop AD diagnosis and therapeutic strategies. In this review, we focus on the differences between Aβ42 and Aβ40 in the molecular mechanism of amyloid aggregations mediated by the two additional residues (Ile41 and Ala42) of Aβ42. The current comprehension of Aβ42 and Aβ40 in AD progression is outlined, together with the structural features of Aβ42/Aβ40 amyloid fibrils, and the aggregation mechanisms of Aβ42/Aβ40. Furthermore, the impact of the heterogeneous distribution of Aβ isoforms during amyloid aggregations is discussed in the system mimicking the coexistence of Aβ42 and Aβ40 in human cerebrospinal fluid (CSF) and plasma.

• 대한환경공학회지
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• 제32권11호
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• pp.1054-1062
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• 2010

휴믹물질의 산화중합반응은 천연 효소나 금속산화물 촉매에 의해 유도될 수 있다. 본 연구에서는 천연 효소인 horseradish peroxidase (HRP)에 의한 휴믹산의 특성 변화와 이러한 변화된 특성이 정밀여과 공정에 미치는 영향을 평가하였다. 정제된 Aldrich 휴믹산(PAHA)이 HRP 및 과산화수소 존재 하에 산화중합되어 보다 크고 복잡한 분자를 형성하였으며, 크기배제크로마토그래피(SEC, size exclusion chromatography, SEC)에서도 평균분자량의 증가가 관찰되었다. 또한, HRP 및 $H_2O_2$ 주입량이 증가함에 따라 PAHA의 분자량은 더욱 증가하였다. 휴믹물질의 화학적 안정성은 산화중합반응에 기인한 휴믹 분자 상호간의 공유결합이 촉진됨에 따라 향상되었으며, 형광 분광 및 적외선 분광 분석 결과, 산화중합반응에 의한 PAHA 분자 작용기의 변화도 확인되었다. 수처리 공정에 미치는 영향을 평가하기 위해, 정밀여과를 적용한 결과, 산화중합반응 산물은 높은 분자량으로 인해 그 제거효율이 크게 향상되었다. 이는 산화중합된 자연유기물이 정밀여과에 의해 제거될 수 있음을 증명하는 것이다.

• 마케팅과학연구
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• 제19권4호
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• pp.24-31
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• 2009

公司生产不同功能, 设计, 颜色的产品. 产品扩散的出现有三个不同的原因. 当存在规模经济, 当这种产品和别的产品一起生产时, 单位成本比单独生产要低. 二, 消费者是异构的, 即它们具有不同的品味, 喜好, 或价格弹性. 一家公司可赚取细分为具有类似特点的不同群体的消费者更多的利润. 例如, 产品扩散通过更准确地满足不同消费者的需要来帮助公司增加利润. 产品扩散的第三个原因是基于战略. 生产一定数量的产品, 不仅可以阻止通过提供给一些少数市场的产品进入, 也使得公司可以有效地应付低价格进入. 通过生产各种产品, 公司可以减少利基, 使潜在进入者有较少进入的诱因. 此外, 企业可以生产新产品来应对进入, 我们称之为战斗品牌. 也就是说, 当一个进入者试图以低廉的价格吸引消费者, 已存在者介绍新的低质量的产品, 同时保持现有产品的价格. 产品扩散的缺点是同型装配. 一些买了高价位的产品的消费者会转向低价位的产品. 此外, 当新产品与对手现有的产品的异化程度不高时, 由于激烈的竞争, 产品扩散会降低利润. 许多研究已经在经济分析和市场营销等领域的产品线竞争的影响. 它们展示了一个垄断者可以通过调整质量来解决市场中的消费者对质量的偏好不同的同型装配的问题. 他们发现, 喜欢高品质的产品的消费者将获得他或她最喜欢的质量, 但没有这方面的偏好的消费者将获得比他或她所喜爱的质量低的产品. 本研究分析了产品的竞争在一个双头垄断市场, 两种不同类型的消费者对质量偏好的影响. 我假设这两家公司将在这个意义上的不对称, 一个运营商可以同时生产高, 低质量的产品, 而一个进入者只能产生低质量的产品. 产品扩散的影响是可以通过比较市场结果来解释, 当已存在的运营商生产两种产品和只生产一种产品时. 在这个案例中, 当已存在的运营商只生产高品质的产品, 由于激烈的竞争, 在喜欢低质量产品的消费群中低质量的产品价格趋于下降. 但由于缺乏竞争, 在喜欢高质量产品的消费群中价格会上涨. 据了解, 当企业在进行价格竞争时, 理想状况是当公司的对 手提高价格时, 此公司也提高价格, 这被称为战略补充. 由于价格是战略性的补充, 我们有两种相反的效果. 事实证明, 一个高品质的产品价格上升, 因为竞争力减弱的积极作用超过了战略互补的负面影响. 这意味着, 已存在的运营商推出了低质量的产品时还需要增加高品质产品的价格. 然而, 在进入者的低质量产品的价格变化是模糊的. 二, 此案例中, 已存在的运营商只生产低品质的产品, 在偏好低质量的消费群中价格往往增加. 但在偏好高质量的消费群中价格往往下降. 低质量产品的价格下降是因为负面影响大于正面影响. 而且, 当已存在的运营商生产两种产品时, 其低质量产品的价格往往较高, 尽管两家的低品质的产品质量一样. 此原因由于对高品质产品价格的负面影响, 运营商没有较大的动机去降低低品质产品的价格. 事实上, 竞争的产品线对利润的影响不仅取决于价格变化, 还取决于销售和同型装配. 如果在边际成本同产品质量的差异相比是适中的话, 产品扩散的积极影响大于负面影响, 从而增加利润. 此外, 如果成本差异是非常大(小), 运营商最好只生产一种低 (高)质量的产品. 而且, 本研究还分析了当公司通过关注战斗品牌来决定产品特征时, 竞争产品线的影响. 最近, 大韩航空和韩亚航空公司建立了廉价航空线路, 分别是Jin线路和釜山线. 来应对Hansung航空和济州航空. 另外, 很多网上书店也进入市场, 例如处于领先地位的实体书店Kyobo已经有了自己的网上书店. 通过战斗品牌, 在它的低品质产品跟新成员比起来有差别时, 一个具有高品质产品的运营商通过生产更多的低质量产品可以增加利润.