• Journal of Pharmaceutical Investigation
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• 제25권4호
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• pp.307-311
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• 1995

Three herbal medicine recipes were tried on the animal model of diet induced hypercholesterolemia to screen for the lipid-lowering effect. The recipes adopted were based on the prescription for atherosclerosis-related symptoms by folk-medicine practioners. Hyperlipidemia was induced in rats by giving the high lipid/cholesterol diet for 7 days. Then, the recipes started with the normal diet. Blood was sampled at 1,2,3 and 5 week-points of the treatment, and levels of total cholesterol, triglyceride, high density lipoprotein and lower density lipoprotein were measured. Dae-shiho-tang decreased total cholesterol level significantly. Hwangryun-haedok-tang and Samhwang-sasim-tang slightly decreased total cholesterol level, although it was not statistically significant.

• 대한한의학방제학회지
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• 제16권2호
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• pp.71-90
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• 2008

東醫寶鑑(DongEuiBoGam) is considered as one of the most valuable medical books for Korean traditional medicine. Since 許浚(Heo Jun), the best physician on his day, wrote 東醫寶鑑(DongEuiBoGam), it has been not only a guidebook for basic medical studies, but also a field manual for clinicians. 東醫寶鑑(DongEuiBoGam) is a medical encyclopedia which integrated more than 81 medial classics. And its contents is well organized according to the symptoms of each disease. So today most clinics refer to 東醫寶鑑(DongEuiBoGam). But if we just read 東醫寶鑑(DongEuiBoGam) and use the prescriptions without understanding, the effect of medicine will be reduced by half. We should totally understand recipes in 東醫寶鑑(DongEuiBoGam) and be able to change the recipes according to the symptoms of each patient's disease. So finding the common traits of the recipes in 東醫寶鑑(DongEuiBoGam) is very important. In this research, the recipes of the fire part(火門) of Various Disease vol. Ⅲ(雜病篇 卷之三) are analyzed according to the traits of each herb in the recipes. And new classification of prescriptions according to the community of their traits is also suggested.

• 대한한의학방제학회지
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• 제28권3호
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• pp.289-300
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• 2020

Objectives : In this paper, We pointed out medico-historical meaning of Hyang'yak Kugŭppang (鄕藥救急方, Medical Recipes of Local Botanicals for Emergency Use), a medical book of Koryŏ Dynasty, breaking from the existing analysis view based on Hyang'yak (鄕藥), local herbs produced in Korean Peninsula. Methods : For that purpose, we analyzed the clinical characteristics of the diseases and symptoms, strategies of treatment, therapeutic tools, drug formulations, composition of herbal formulas in Hyang'yak Kugŭppang. Results : The following characteristics were confirmed in Hyang'yak Kugŭppang. First, it contained a way to cope with the diseases and symptoms that do not have to check the exterior, interior, cold, and heat. Also, it introduced basic strategies such as reducing, facilitating flow, draining downward, warming, or tonifying, etc. It mainly included herbal medicine as the therapeutic tools, and introduced formulas composed by single herb than complex recipes. It suggested external applications more than internal use, and proposed formulations in the form of decoctions or powders, etc. The herbs of formulas were used by experience without explanations of nature & taste, efficacy of each herbs. Conclusions : Hyang'yak Kugŭppang is a book of medical recipes for emergency use that has been distributed to help gentries, even if they do not have professional medical knowledge, to instantly cope with diseases and symptoms with medicines that are easy to obtain. Previous researches has analyzed the value of Hyang'yak Kugŭppang as a collection of information of hyang'yak, and used it as a historical basis of the uniqueness of Korean medicine. Since Hyang'yak Kugŭppang is not a book specialized for herbs, but rather a clinical medical book that introduces recipes for specific symptoms of diseases, if we pay attention to the clinical characteristics of Hyang'yak Kugŭppang, it will provide an opportunity to describe Koryŏ or Korean medicine in a new way.

• 대한한의학방제학회지
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• 제15권1호
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• pp.37-47
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• 2007

許浚(Heo Jun), the best physician on his day, wrote 東醫寶鑑(DongEuiBoGam, 1613) based on his clinical experience as a court doctor and life-long study of over 500 medical books. Now most clinicians consult 東醫寶鑑(DongEuiBoGam) for its practicality. And it is also considered as one of the most valuable medical books for basic medical studies. As 許浚(Heo Jun) mentioned on the 東醫寶鑑(DongEuiBoGam) preface. we should practice flexibility on the interpretation of the medical classics instead of binding ourselves to the precedents. But worship of 東醫寶鑑(DongEuiBoGam) may hinder the studying of new pathways. The treatment and its understandings of a disease should be based on objectivity of observation. Finding the common traits of the recipes in 東醫寶鑑(DongEuiBoGam) is important for the study of 東醫寶鑑(DongEuiBoGam). Accordingly, group synthesis of symptoms and resultant classification of recipes are vital. In this research, symptoms listed in the head part(頭門) of External Shape vol. I(外形篇 卷1) of 東醫寶鑑(DongEuiBoGam) are synthesized into 3 different parts: head-wind syndrome(頭風證), dizziness(眩暈), headache(頭痛). Classification of prescriptions according to these 3 parts is also suggested.

• 한국의사학회지
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• 제33권1호
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• pp.99-112
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• 2020

In this study, we examine the changes to Korean medicine that occurred when 'proprietary medicines' (賣藥) swept through the pharmaceutical market during the Japanese occupation (1910-1945 C.E.). Proprietary medicine during the Japanese colonial period took various forms including ready-made, over-the-counter, patent, and nostrum type pharmaceuticals. This paper examines how Korean medicine, which was the dominant form of medicine during the Joseon Dynasty, was forced to adapt to the rise of proprietary medicines. We found that the prescription of Korean medicine herbal decoctions became more like proprietary medicine in the way that they were formulated. In addition, prescriptions in Korean medicine books were reformulated with prescriptions and medicines from outside the tradition. Proprietary medicines, many of which were made with secret recipes handed down in a family, also attracted attention. Such prescriptions were made famous through advertisements and further influenced future Korean medicine doctors. New prescriptions took advantage of the trust and authority existing in traditional Korean medicine by introducing ginseng and traditional medicinal herbs such as deer antler velvet (鹿茸, Cervi Parvum Cornu). This paper argues that proprietary medicine of the Japanese colonial period distorted the concept of traditional herbal medicine.

• 대한한의학원전학회지
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• 제35권3호
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• pp.21-31
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• 2022

Objectives : The Gyotae-hwan formula has traditionally been applied to conditions of fearful throbbing[怔忡] and insomnia due to disharmony of the Heart and Kidney, of which experimental and clinical research has been carried out while those on its pathological mechanism and constituent compatibility have been inadequate. Methods : Pathological mechanism and constituent compatibility of the Gyotae-hwan formula as listed in the 『Comprehensive Medicine According to Master Han』(韓氏醫通) and the『Simple Recipes for Four Disciplines』(四科簡效方) were analyzed. Findings from recent researches searched using the keywords '交泰丸' and '교태환' in the OASIS and CNKI databases were referenced as well. Results : The Gyo-tae hwan was first mentioned in the text 『Comprehensive Medicine According to Master Han』by Mao Han in terms of constituent medicinals and application while measurements and name of formula were not listed while the concept of harmony between the Heart and Kidney was mentioned. In the『Simple Recipes for Four Discipline s』 written by Shixiong Wang, measurements of constituent medicinals, usages and name of formula were finally mentioned, along with its efficacy to treat fearful throbbing and insomnia due to disharmony between the Heart and the Kidney. Conclusions : In conclusion, the Gyo-tae hwan uses Coptidis Rhizoma as chief herb and Cinnamomi Cortex as assistant herb to change the state of disharmony between the Heart and Kidney to a harmonious state, treating insomnia and fearful throbbing.

• Korean Journal of Acupuncture
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• 제27권3호
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• pp.79-95
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• 2010

Objective : In this study, we try to identify the herbal formulated by Heo Im from Kyeongheombang(經驗方), and investigate its medical property. Method : Those articles referenced from Heo Im's herbal formulas in "Sauikyeongheombang(四醫經驗方)" were extracted and results were quantitatively analyzed. From extracted empirical formulas, those categorized as externally applicable formulas were grouped by several standards and their medical significance was analyzed. Results and Conclusions : 85 and 66 articles were designated to be referred from Heo(許) in "Sauikyeongheombang" and "Uibanghapbu(醫方合部)" in each category, and 263 and 155 were identified to be Heo Im formulas, respectively. Externally applicable formulas in Heo Im's empirical recipes have following characteristics. First, various methods were used by Heo Im. Second, Heo Im's empirical formulas suggest useful clinical information maximizing therapeutic effect, which is of much value, originated from his practical experiences as a clinician. Third, Heo Im's therapy favorably succeeds the tradition of Hyangyak-medicine and Empirical -medicine. From this information, Heo Im is thought to have had rich insight and experience, not only in acupuncture but also in the prescription of herbal formulas at those days.

• 대한약침학회지
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• 제2권1호
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• pp.27-38
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• 1999

It was the Study for more deep understanding about the Frozen shoulder by literature investigation. The following result were obtained. : 1. The reason of Frozen shoulder is inflamatory reaction, degeneration, continual fixing, injury, etc. 2. The symptom of Frozen shoulder is shoulder pain, night pain, limit of joint movement. 3. Frozen shoulder is classified primary and secondary types and in the oriental medicine, is classified six types by the three Yin&Yang channels of the hand 4. Jackin's exercise or codman's exercise is used for kinesiatrics. 5. $Ky\check{o}njong$(SI9), nosu(SI10), $ch'\check{o}njong$(SI11) are in commonly used acupuncture point. 6. It is used to the Tongbihanseungbang, Small-intestine jeong kyuck in SA-AM Acupuncture. 7. It is used to the TrPs of subscapularis in MPS. 8. It is used to Frozen shoulder the Sin-kwan, Sahwajung, etc. in Dong-si Acupuncture. 9. It is used the I, HO or HN to Frozen shoulder treatment in Herbal Acupuncture. 10. Using the Electro-acupuncture, we select the point according to the channels. 11. Cupping or Moxibustion is commonly used with Acupuncture. 12. Commonly used recipes are Seokyungtang, Oyacksungisan, Banhakumchultang, etc.

• 대한한의학방제학회지
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• 제12권1호
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• pp.1-27
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• 2004

The following are the conclusions obtained by the philological study of the prescriptions introduced in Dongeuybogam such as Pyungwuisan, Pyungwuisan-added prescriptions, Pyungwuisan blended prescriptions: 1. Pyungwuisan and drugs based on Pyungwuisan were prescribed for stomach diseases, food poisoning, indigestion, impaired spleen, symptoms developed by dampness, diseases caused by changing water, diarrhea, edema, malignant malaria, an intestinal convulsion, blood in excrement, malaria, abortion, sparrow eye. 2. Dual prescriptions using Pyungwuisan and other independent prescriptions were applied to internal diseases concerning digestion, diarrhea and dysentery, abscess, intestinal swelling jaundice, symptoms developed by dampness, malaria, vomit, etc. 3. Etiological factors and diseases for which Pyungwuisan and medicines based on Pyungwuisan, dual prescriptions using Pyungwuisan were prescribed, were surveyed to include indigestion, weak spleen and stomach, drying dampness of spleen and stomach, dysfunctioning gall bladder, infection, damaged internals, external sensitiveness and internal damage, hypochondria, chilliness due to lack of chi. 4. A prescription for each disease needed specially added medicines to Pyungwuisan as the following: 1) For indigestion and dyspepsia, Pyungwuisan were prescribed with optional addition of Hoisaengsan, Sagunjatang, Ryukgunjatang, Ijintang, Sosihotang, etc., according to the symptoms, and were most frequently used with aromatic and digestive medicines such as mawwa medivata fermentata, malt, natgrass galingale rhizome, vilous amomum fruit, aucklandia root, round cardamom seed etc. 2) For diseases originated from damage by coldness, Pyungwuisan was taken with suitable amount of Jichulhwan, Hyangsosan, Hyangyusan, according to the symptoms. 3) For diarrhea and dysentery, Pyungwuisan were prescribed with the recipes of Oryeongsan, Sambaektang, Ijintang. 4) For jaundice, prescriptions always included natgrass galingale rhizome in the recipe of Pyungwuisan. 5) For malaria, mostly added prescriptions to Pyungwuisan were Sagunjatang, Ryukgunjatang, Ijintang, with usual addition of antifebrile dichroa root, tsaoko, green tangerine orange peel. 6) Pyungwuisan was prescribed with Hoisaengsan for vomit, with Oryeongsan for edema, and with kinds of Ueolgukhwan for hypochondria.

• 동아시아식생활학회지
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• 제23권5호
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• pp.645-653
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• 2013

생(生), 증(蒸), 주증(酒蒸) 건조 맥문동(LTD, LTSD, LTASD)과 생(生), 증(蒸), 주증(酒蒸) 건조 볶음 맥문동 시료(LTDR, LTSDR, LTASDR)의 가용성 고형물, 전당, 환원당과 항산화 효과, 관능평가를 실시한 결과는 다음과 같았다. 가용성 고형분 함량은 건조 후 볶음 처리한 시료(LTDR, LTSDR, LTASDR)가 모든 건조 맥문동 시료(LTD, LTSD, LTASD)보다 많았다. 전당과 환원당은 볶음 유무에 따라서 모든 열처리한 시료가 생건조 시료(LTD)와 비교하여 유의적으로 함량이 많았으며, 환원당은 특히 주증건조 볶음 시료(LTASDR)가 가장 많은 것으로 나타났다. 일정온도에서 환원당의 함량이 증가하는 이유는 열분해로 인한 저분자량의 올리고당이나 덱스트린 등의 환원당 생성량이 소모되는 양보다 현저히 많기 때문이다. 갈변도는 볶음 처리를 함에 따라 모든 볶음 맥문동 시료가 유의적으로 높은 값을 나타내었다. 특히 주증 건조볶음(LTASDR)의 갈변도가 높았는데, 주증(酒蒸)할 때에 이용된 청주에 함유되어 있는 당이 맥문동에 흡수되었고, 이에 따라 갈변도가 높아졌을 뿐 아니라, 항산화와 관련된 갈색 반응이 더 활발하게 일어나고, Maillard 반응의 중간생성물이 증가되어 여러 가지 항산화 효과가 나타났다. 항산화 활성 실험에서도 모든 건조 맥문동에 비하여 볶음 맥문동 시료의 항산화 활성이 높게 측정되었으며, 특히 주증 건조 볶음 시료(LTASDR)가 DPPH 라디칼 소거능, ABTs 라디칼 소거능, 아질산염 소거능, XOase 저해활성에 있어서 월등히 높은 수치를 나타내었다. 주증건조 볶음 시료(LTASDR)가 생건조 맥문동(LTD)의 열수 추출물에 비하여 항산화 효과가 대체적으로 유의적으로 높게 측정된 결과는 술로 찌고, 볶는 과정 중에 갈변물질이 더 많이 생성되었고, 수용성 성분 추출이 용이하도록 조직이 변화된 결과로 사료된다. 색(color), 향미(flavor), 단맛(sweetness), 구수한 맛(tasty flavor), 전반적인 기호도(overall acceptance)는 전체적으로 볶음 처리를 함에 따라 유의적인 차이로 기호도가 향상되었으며, 볶음 처리한 시료 간에는 유의적인 차이가 없었다. 본 연구를 통해 찌거나 주증 처리하여 볶은 맥문동 시료의 열수 추출물이 생건조 맥문동(LTD)이나 생건조 볶음 맥문동(LTDR)에 비해 항산화성이 높게 측정되었음을 확인하였고, 전체적인 관능평가에 있어서 높은 점수를 받음으로써 기능성이나 맛에 있어서 긍정적인 결과를 얻었다. 그러므로 맥문동을 음료나 약선 등에 활용할 때에 맥문동의 전처리는 건조만하여 추출하기 보다는 찌거나 술을 도포하여 찐 다음 건조하여 볶는 방법이 적합한 것으로 생각된다.