• Journal of Sasang Constitutional Medicine
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• v.19 no.2
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• pp.40-52
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• 2007

1. Objectives and Methods The purpose of this study was to objectify the diagnosis of Sasang Constitution. 63 Male Juvenile's and 151 Female Juvenile's sentences were analyzed into 73 factors like Pitch, APQ, Shimmer, Octave and Energy, etc. Juvenile's sentences were classified into 6 categories: total Male Juvenile group, under 12 years old Male Juvenile grout, over 13 years old Male Juvenile group, total Female Juvenile group, under 12 years old Female Juvenile group and over 13 years old Female Juvenile group. 2. Results 1) In Total Male Juvenile group, there were no significant differences among constitutional groups in APQ and Octave segment. Taeumin's Center freq.(3) was significantly high compared with Soyangin group. Soeumin's Center freq.(5) was significantly high compared with Soyangin and Taeumin groups. Taeumin's Octave3 Shimmer was significantly high compared with Soeumin group. Soeumin's Octave6 Shimmer was significantly high compared with Taeumin group. Solyangin's D# Tot E was significantly high compared with Taeumin group. 2) In Under 12 years old Male Juvenile group, there were on significantly among constitutional groups in Pitch, APQ, Octave and Energy segment. Taeumin's Octave3 Shimmer and G Shimmer(1) were significantly high compared with Soeumin group. 3) In Over 13 years old Male Juvenile group, there were no signigicant differences among constitutional groups in Pitch, APQ and Shimmer segment. Soyangin's and Soeumin's Octave6 were significantly high compared with Taeumin group. Soyangin's $0k{\sim}2k$ Total Sum, $0k{\sim}2k$ Dev., $2k{\sim}4k$ Total Sum, $2k{\sim}4k$ Dev., A Dev.(1), D# Dev.(1) and G# Dev.(1) were significantly high compared with Taeumin group. Soyangin's and Soeumin's G# Tot E were significantly high compared with Taeumin group. 4) In Total Female Juvenile group, there were no significant differences among constitutional groups in Pitch and APQ segment. Soeumin's Octave4 Shimmer was significantly high compared with Soyangin group. Soyangin's Octave6 was significantly high compared with Soeumin group. Solyangin's 2k-4k Total Sum and B Tot E were significantly high compared with Soeumin group. 5) In Under 12 years old Female Juvenile group, there were no significant differences among constitutional groups in APQ and Energy segment. Soeumin's and Taeumin's Center Pitch and Pitch were significantly high compared with Soyangin group. Soyangin's Center freq.(1) and Center freq.(7) were significantly high compared with Soeumin and Taeeunin groups. Soyangin's and Taeumin's B Shimmer(1) and F# Shimmer(1) were significantly high compared with Soeumin group. Soeumin's D Shimmer(1) was significantly high compared with Soyangin group. Taeumin's and Soeumin's G# Shimmer(1) were significantly high compared with Soyangin group. Soyangin's and Taeumin's Octave2 were significantly high compared with Soeumin group. 6) In Over 13 years old Female Juvenile group, there were no significant differences among constitutional groups in Pitch, APQ and Octave segment. Soeumin's Octave4 Shimmer was significantly high compared with Soyangin group. Soyangin's B Dev.(1) and F Dev.(1) were significantly high compared with Soeumin group. 3. Conclusions In juvenile groups, some sound factors are regarded as useful. PSSC are thought to be the objertive way to diagnose the Consitution and more participants are needed to get more efficiencies using PSSC.

• Korean Journal of Poultry Science
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• v.39 no.2
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• pp.143-149
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• 2012

This work was carried out to investigate the performance of growing period of large-type Korean native ducks. A total of four hundred twenty female and male duck chicks generated from A and B strains of ducks. Groups were four crossbreds (3 replications/crossbred, 35 birds/replication) as $2{\times}2$ factors (2 strains, A and B; 2 genders, female and male). On the body weight, male of B strains was the highest among 4 treatments after the age of 4 week (P<0.05). Body weight of B strain was higher than that of A strain at all period (P<0.05). Body weight of male was higher compared to that of female after the age of 4 week (P<0.05). On the body weight gain, male of B strain was the highest and female of A strain was the lowest among 4 treatments at 0~8, 0~12, 0~16 and 0~20 weeks (P<0.05). Body weight gain of male was higher than that of female after the age of 4 week (P<0.05). On the feed intake, male of B strain was the highest among 4 treatments from the age of 0 week and to the age of 4, 12, 16 and 20 week (P<0.05). Feed intake of male was higher than that of female at 0~12, 0~16 and 0~20 weeks (P<0.05). On the feed conversion ratio, male of B strain was the highest among other treatments 0~4 weeks and female of A strain was at 0~8 and 0~12 weeks (P<0.05). Feed intake of female was higher compared to that of female at 0~8 weeks and male was high at 0~20 weeks. These results provided the basic data on the record of growing phase of large-type Korean native ducks.

• Korean Journal of Materials Research
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• v.8 no.12
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• pp.1165-1169
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• 1998

A single crystal cast blade was manufactured by CMSX 6, one of the first generarion nickel based single crystal superalloys by the selector method in a vacuum furnace. The single crystal has been grown with cooling rate of 2.5 mm/min, after pouring the molten alloy of 163$0^{\circ}C$ to the mold heated to 150$0^{\circ}C$. The cast structure could be classified into matrix (dendrite) and eutectic regions in ${\gamma}$'shape and size. The eutectic region showed higher Ti content. As the additional results of ${\gamma}$'precipitates by EPMA and CBED analysis the ${\gamma}$'size was less than 0.5~0.7$\mu\textrm{m}$, showing the chemical composition close to Ni$_3$Al of Ll$_2$ lattice structure. But ${\gamma}$'size has increased to bigger than 1.0$\mu\textrm{m}$, being near to eutectic region, changing its shape to bar or huge block types. These showed the chemical structure near to Ni$_3$Ti of D $O_{24}$ lattice structure. Therefore, ${\gamma}$'morphology of dendrite and eutectic regions depends absolutely on its chemical composition and lattice structure.

• Journal of the Korea Organic Resources Recycling Association
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• v.9 no.3
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• pp.55-69
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• 2001

To study the possibility of agricultural utilization of seafood processing wastewater sludges, the changes of temperature and humus, the form of organic matter and nitrogen and the germination ratio of plant during the composting were investigated. The results were summarized as follows. Temperature was rapidly increased at early stage of composting, reached to $67{\sim}76^{\circ}C$ in highest temperature at 3~5 days, and then decreased gradually fallen to $40{\sim}50^{\circ}C$ at 19 days after composting, at the point was upset firstly. The third upset was conducted at 60days after composting, and then the temperature was little changed. The contents of total organic matters in the compost for composting were down 4.5~8.0%. Ether extractable materials, resins and hemicellulose contents of the organic matters for composting were decreased with 35~77%, 32~69% and 19~30%, respectively. And cellulose, lignins and unknown materials contents in the organic matters for composting were increased a little, but water soluble polysaccharides of organic matters were little changed. Total nitrogen, amino sugar and amino acid nitrogen contents in the compost for composting were decreased with 20~42%, 11~49% and 23~65%, respectively. The contents of humic acid in the compost for composting were little changed, but contents of fulvic acid in the compost for composting were decreased gradually. Germination ratio of radish, chinese cabbage and cucumber were over 90%, when the compost produced at 30 days after composting was tested on plant germination.

• Journal of the Korean Society of Food Science and Nutrition
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• v.46 no.5
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• pp.646-652
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• 2017

The aim of this study was to investigate method validation for determination of sesamol, sesamin, and sesamolin in non-fermented sesame and fermented sesame by bioconversion. For validation, the specificity, linearity, precision, accuracy, limits of detection (LOD), and quantification (LOQ) of sesamol, sesamin, and sesamolin were measured by HPLC. Linearity tests showed that the coefficients of calibration correlation ($R^2$) for sesamol, sesamin, and sesamolin were 0.9999. Recovery rates of lignan contents in non-fermented and fermented sesame were high in the ranges of 100.27~115.10% and 98.43~114.90%, respectively. The inter-day and intra-day precisions of sesamin and sesamolin analyses for non-fermented and fermented sesame were 0.27~1.94% and 0.25~0.69%, respectively. The LOD and LOQ were $0.23{\sim}0.34{\mu}g/g$ and $0.70{\sim}1.03{\mu}g/g$, respectively. These results indicate that the validated method is appropriate for the determination of sesamol, sesamin, and sesamolin.

• Korean Journal of Plant Resources
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• v.30 no.4
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• pp.352-363
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• 2017

To investigate skin-whitening effect of Adenophora triphylla var. japonica sprout extract, antioxidant activity, inhibitory effect on tyrosinase and melanin synthesis in B16/F10 melanoma cell were examined. Total phenolic content (246.25 mg GAE/g) and total flavonoid content (303.94 mg RE/g) of ethyl acetate fraction from Adenophora triphylla sprout (EFAT) showed the highest contents than other fractions (n-hexane, chloroform and distilled water). Antioxidant activities of EFAT has been evaluated using ABTS, DPPH radical scavenging activities, FRAP and inhibitory effect of lipid peroxidation. EFAT showed excellent radical scavenging activity and inhibitory effect on MDA production. Inhibitory effect of tyrosinase as a major enzyme of melanin synthesis was also measured. In these results, EFAT showed higher inhibitory effect against L-DOPA (51.27%) than L-tyrosine. $IC_{50}$ value on ${\alpha}-glucosidase$ was $41.93{\mu}g/ml$. In B16/F10 melanoma cells, EFAT inhibited melanin synthesis at $200{\mu}g/ml$ concentration (about 42% decrease). Finally, main physiological compounds of EFAT were identified as a rutin and a chlorogenic acid using high performance liquid chromatography.

• Korean Journal of Ichthyology
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• v.18 no.3
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• pp.223-233
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• 2006

The annual and spatial changes in the species composition of catch off Yeosu were analyzed using the daily sales slip catch data by a set net in the inshore waters off Dolsan Islands in Yeosu from April to October 2001, off Yeon Islands of Yeosu from April to October 2002 and in the offshore waters off Dolsan Islands of Yeosu from April to December 2003, respectively. Scomberomorus niphonius, Seriola spp., Trichiurus lepturus, Engraulis japonicus, Sarda orientalis, Todarodes pacificus, Pampus echinogaster, Sardinella zunasi, Scomber japonicus, Lophius litulon and Loligo beka were dominant species in abundance, indicating that pelagic fish were mainly caught by a set net off Yeosu. S. zunasi, P. echinogaster, Platycephalus indicus and L. beka inhabited mainly in the inshore waters, and S. niphonius, Seriola spp., T. lepturus, P. echinogaster, T. pacificus, Takifugu porphyreus and Pagrus major resided mainly in the offshore waters as the pelagic resident species. E. japonicus was a representative dominant species moving between the inshore and the offshore waters seasonally. S. zunasi and E. japonicus occurred in the inshore waters, and E. japonicus, L. litulon and Seriola spp. begain to be caught in the deep offshore waters in spring. Total catch was high during the summer season by migration of the open sea species such as T. lepturus, S. niphonius, S. japonicus, Seriola spp., S. orientalis, P. echinogaster and T. pacificus. In fall, S. niphonius, E. japonicus, Sphyraena pinguis, Siganus fuscescens and Leiognathus nuchalis were dominant in the inshore waters, and S. niphonius, P. echinogaster, Hyporhamphus sajori, S. japonicus and T. lepturus continued to occur from summer in the offshore waters but total catch decreased, indicating the typical seasonal variation pattern of the temperate region. Most of catchable fishes by a set net were the pelagic species showing a significant temporal variation. Collection and analysis of daily catch data by large set nets can be used to determine seasonal variation in species composition of pelagic fish in a study area.

• Journal of the Korean Society of Marine Environment & Safety
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• v.19 no.5
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• pp.439-458
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• 2013

Temporal and spatial variations of water quality were investigated in the Cheonsu Bay of Yellow Sea, Korea from 2010 to 2011. Water samples were collected at 16 stations and physicochemical parameters were analyzed including water temperature, salinity, suspended solids (SS), chemical oxygen demand (COD), dissolved oxygen (DO), Chlorophyll a and nutrients. Spatial distribution patterns of all survey items were not clear among stations but the bimonthly variations were distinct except the bottom water of the suspended solids. The trend analysis by principal component analysis (PCA) during 2 years revealed the significant variations in water quality in the study area. Spatial water qualities were discriminated into 3 clusters by PCA; station cluster in the surface water 1, 2~11, and 12~16, the bottom water 1, 2~7, and 8~16. Annual bimonthly water qualities were clearly discriminated into 3 clusters by PCA. But tend of cluster in the surface and bottom water was difference, period most of the research was low in nutrient. Ecology-based water quality criteria was a good level of grade II. Bimonthly results are shown as III grade(normal) at June and August, II grade(good) at October and December and I grade for February and April. Water quality was showed by the input of fresh water same as those of Kyoungin coastal area, Asan coastal area, Gunsan coastal and Mokpo coastal area in the Cheonsu.

• Journal of Life Science
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• v.27 no.9
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• pp.1020-1030
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• 2017

Epidemiology studies have reported a reduced incidence of colon cancer among populations that consume a large quantity of ${\omega}3-polyunsaturated$ fatty acids (${\omega}3-PUFAs$) of marine origin. Herein, we demonstrated a mechanism of anticancer action of ${\omega}3-PUFAs$, showing that they suppressed invasion and tumorigenicity in colon cancer cells. Docosahexaenoic acids (DHA) inhibited the cell growth of HT29 cells. This action likely involved apoptosis, given that the DHA treatment increased the cleaved form of PARP and sub G1 cells. Moreover, the invasiveness of HT29 cells was inhibited following DHA treatment, whereas arachidonic acid (AA) had no effect. The levels of Matrix-metalloproteinase-9 (MMP-9) and MMP-2 mRNA decreased after DHA pretreatment. DHA treatment inhibited MMP-9 and MMP-2 promoter activities and reduced VEGF promoter activity. DHA pretreatment also inhibited the activities of prostaglandin-2 (PGE2)-induced MMPs and the VEGF promoter. Cyclooxygenase-2 (COX-2) overexpression increased the activity of MMPs and that of the Vascular endotherial growth factor (VEGF) promoter in HT29 cells, and DHA inhibited NF-kB and COX-2 promoter reporter activities. As shown by in vivo experiments, when mouse colon cancer cells (MCA38) were implanted into Fat-1 and wild-type mice, both the tumoral size and volume were dramatically inhibited in Fat-1 transgenic mice. Furthermore, TUNEL-positive cells increased in tumors from Fat-1 mice compared with wild mice. In immunohistochemistry, the intensity of CD31 in Fat-1 tumors was weaker. These findings suggest that ${\omega}3-PUFAs$ may inhibit tumorigenicity and angiogenesis as well as cancer cell invasion by suppression of COX-2, MMPs and VEGF via the reduction of NF-kB in colon cancer.

• Korean Journal of Medicinal Crop Science
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• v.13 no.6
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• pp.217-225
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• 2005

This study was carried out to investigate the genotoxicity in comet and in vitro micronucleus assay and mutagenicity in Ames test of the extracts from leaves and stem of Morus alba L. The samples showed a very weak cytotoxicity on the NIH/3T3 cells by SRB assay. The cell viability of the extracts and fractions from leaves and stems of Morus alba L. was 80% over at $500\;{\mu}g/ml$, and that of the chloroform fractions from leaves and stems showed lower than others. The genotoxicity at $250\;{\mu}g/ml$ of 100% EtOH and water extracts on the NIH/3T3 cells in comet assay was about 40% compared to positive control, and most fractions from 100% EtOH extract of the leaves showed stronger genotoxicity than that offractions from the stem. The genotoxicity with S-9 mix in vitro micronucleus assay of the 100% EtOH and water extracts form Morus alba L. did not indicate any significant difference as compared with control group. The cytokinesis-binucleated cells were showed in the hexan, chloroform, ethylacetate and butanol fractions from the extract of the leaves without S-9, and sample with S-9 showed CB cells in the chloroform fraction from the leaves. In the Ames test, the water and 100% ethanol extracts of Morus alba L. did not have a strong mutagenicity in TA98 and TA100, but the fractions of organic solvents of the ethanol extract had $10{\sim}26%$ of mutagenicity on the TA100 strain.