• 대한수의학회지
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• 제11권1호
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• pp.97-102
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• 1971

60 cases of swine and bovine ovaries were investigated for detecting the homosiderin pigment by means of Perl's prussian blue reaction. The results abtained were as follows; 1. Among the 30 cases of normal adult swine ovaries, 20 cases (66.6%) were presented as positive. 2. The hemosiderin pigment was detected in corpus albicans, connective tissue of corpus luteum, theca externa of follicles and interstitial tissue of ovary in swine. 3. The morphological characteristics of the hemosiderin pigment of swine ovaries were fine and coarse granules or amorphous and homogenous pigment. 4. In 30 cases of bovine ovaries, the hemosiderin pigment was not detected.

• 동의생리병리학회지
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• 제18권3호
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• pp.924-929
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• 2004

Pigmented villonodular synovitis is a rare proliferating process of the synovium, tendon sheaths and bursae usually affecting the bone and joints. The disease can be localized or diffuse. Patients with this condition typically present with symptoms of mild discomfort and associated swelling of the involved joint. However, the spectrum of presentations is broad. Diagnosis of Pigmented villonodular synovitis can be clinically difficult, and plain radiographs are usually nonspecific. Magnetic resonance imaging is a highly diagnostic modality in characterizing pigmented villonodular synovitis when it contains hemosiderin deposits exhibiting low signal intensity on all pulse sequences. Magnetic resonance imaging is recommended for accurate preoperative staging of the disease and for follow up after treatment. I report a case of pigmented nodular synovitis in the knee joint, with review of literatures.

• 대한세포병리학회지
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• 제15권1호
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• pp.60-64
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• 2004

The macrofollicular variant of papillary thyroid carcinoma (MVPC) is characterized by macrofollicles occupying more than half of the tumor and demonstrating nuclear features of classic papillary carcinoma. It is difficult to recognize on fine needle aspiration (FNA) cytology due to the paucity of aspirated neoplastic cell clusters, especially when the tumor is associated with extensive areas of hemorrhage. Case: A 34-year-old female presented with a well-demarcated nodule in the thyroid gland, diagnosed as a benign nodule on ultrasonography and computed tomography. FNA cytology smear revealed a few small aggregates of follicular cells with morphological features suspicious for papillary carcinoma, set in a background of hemorrhage, inflammatory cells, and hemosiderin-laden macrophages. Intraoperative frozen section revealed macrofollicular nests filled with hemorrhage and composed of follicular cells demonstrating nuclear clearing and grooves. Conclusion: MVPC is a rare but distinctive variant of papillary carcinoma, which is easily mistaken for adenomatous goiter or benign macrofollicular neoplasm on radiologic findings. The cytopathologist should alert oneself on encountering benign radiologic findings and any smear composed of scant numbers of follicular cells with nuclear features suspicious for papillary carcinoma despite the bland-looking background of hemorrhage and hemosiderin-laden macrophages, and recommend intraoperative frozen sections for a definite diagnosis.

• 한국어병학회지
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• 제18권1호
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• pp.99-103
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• 2005

스쿠티카섬모충에 감염된 자주복의 장, 비장, 신장, 정소, 뇌, 연골 그리고 육질부에 충체의 분포를 조사하였다. 실험어는 사조 CS(주)에서 사육중인 자주복 중 스쿠티카섬모충에 감염된 자주복을 이용하였다. 스쿠티카섬모충은 장, 비장, 신장, 정소, 뇌, 연골, 육질부의 기관을 덮는 결합조직에 분포하고 있다. 뇌에 감염되었을 때 막성조직과 시엽피질 사이가 벌어지는 증상이 있었다. 비장에서 hemosiderin이 과다 침적되는 증상을 제외한 다른 내부 조직과 기관에서는 병리적 증상을 볼 수가 없었다.

• 대한수의학회지
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• 제22권1호
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• pp.67-74
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• 1982

만성(慢性) 소화기장애(消化器障碍)로 수술(手術)을 받고 폐사한 3세의 개를 부검(剖檢)하여 복강(腹腔)에서 커다란 균종(菌腫)을 발견하였다. 이 개의 품종(品種)은 Labrador Retriever 종(種)이고 프랑스에서 난소적출(卵巢摘出) 수술(手術)을 하여 한국(韓國)에 데려왔다. 균종(菌腫)은 직경(直徑) 8~15cm, 두께 2~6cm에 달하는 종류(腫瘤)로서 비미부(脾尾部)의 복면(腹面), 공장(空腸), 회장(廻腸), 맹일결장(盲一結腸)의 일부 장벽(腸壁) 및 좌측 횡격막(橫隔膜)과 단단한 유착(癒着)을 일으키고 있었다. 균종(菌腫)의 단면(斷面)에서는 회갈색(灰褐色)에 육아조직(肉芽組織)에 율립대(栗粒大)의 황백색(黃白色) 농양과립(膿瘍顆粒)이 밀발(密發)해 있는 것을 알 수 있었다. 병소부위(病巢部位)의 조직학적(組織學的) 검사(檢査)에서 장벽(腸壁)의 내수주근층(內輸走筋層)의 극심한 대상성비대(代償性肥大), 균강(菌腔)과 관련된 복강장기(腹腔臟器)에서의 광범한 hemosiderin 침착(沈着) 및 비주동맥(脾柱動脈)의 혈전증(血栓症)과 그 중막(中膜)의 atheroma 성(性) 비후(肥厚)등을 관찰하였다. 이와 같은 만성병변(慢性病變)으로 인하여 이 개는 정상개의 반 밖에 자라지 않고 있었다. 균종(菌腫)내의 균괴(菌塊)를 현미경 관찰하여 균사(菌絲)와 후막포자(厚膜胞子)의 특징으로써 Ailescheria boydii 의 감염(感染)이 추정되었다.

• Journal of Korean Neurosurgical Society
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• 제56권3호
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• pp.237-242
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• 2014

Objective : The purpose of this study was to investigate the clinical features and outcomes of pediatric cavernous malformation (CM) in the central nervous system. Methods : Twenty-nine pediatric patients with supratentorial CM underwent microsurgical excision. In selected cases, transparent tubular retractor system (TTRS) was used to reduce retraction injury and intraoperative neuromonitoring (IONM) was held to preserve functioning cortex. Patients' demographics and symptoms were reviewed and surgical outcomes were discussed. Results : The main initial clinical manifestations included the following : seizures (n=13, 45%), headache (n=7, 24%), focal neurological deficits (n=3, 10%), and an incidental finding (n=6, 21%). Overt hemorrhage was detected in 7 patients (24%). There were 19 children (66%) with a single CM and 10 (34%) children with multiple CMs. In 7 cases with deep-seated CM, we used a TTRS to minimize retraction. In 9 cases which location of CM was at eloquent area, IONM was taken during surgery. There was no major morbidity or mortality after surgery. In the 29 operated children, the overall long-term results were satisfactory : 25 (86%) patients had no signs or symptoms associated with CMs, 3 had controllable seizures, and 1 had mild weakness. Conclusion : With the assistance of neuronavigation systems, intraoperative neuromonitoring, and TTRS, CMs could be targeted more accurately and excised more safely. Based on the satisfactory seizure outcome achieved, complete microsurgical excision in children is recommended for CMs presenting with seizures but removal of hemosiderin-stained areas seems to be unnecessary.

• Investigative Magnetic Resonance Imaging
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• 제24권1호
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• pp.51-54
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• 2020

Superficial siderosis is attributed to hemosiderin deposition in the subpial layers of the nervous system. The clinical features of infratentorial superficial siderosis (ISS) are hearing loss, cerebellar ataxia, and corticospinal tract signs and the most common cause of idiopathic ISS is a dural defect. As magnetic resonance imaging (MRI) has advanced, the diagnosis of infratentorial superficial siderosis can be confirmed by unique radiological findings in MRI. Here, we report on a female patient diagnosed with idiopathic ISS by means of clinical symptoms and radiological findings.

• 대한족부족관절학회지
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• 제9권2호
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• pp.220-223
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• 2005

Pigmented villonodular synovitis (PVNS) in ankle is relatively uncommon. This disorder results in increased proliferation of synovium causing villous or nodular changes containing histiocytes, fibroblasts, multinucleated giant cell, and hemosiderin. PVNS is classified into two different type : localized and diffuse. Diffuse type of PVNS in ankle is more common than localized type. Also, recurrence of diffuse type is more frequent. We report a case of diffuse type of PVNS which was recurred soon after the excision.

• 한국임상수의학회지
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• 제16권1호
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• pp.214-217
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• 1999

An 8-month-old male orangutan (Pongo pygmaeus) housed in Everland Zoo-logical Gardens died after having 10 day history of depression, anorexia and acute respiratory distress. On necropsy, the lung failed to collapse and showed diffuse red consolidation. Microscopically, the alveoli were filled with large amounts of red blood cells, fibrin and varing number of hemosiderin-laden macrophages. The alveolar septa were thickened due to infiltrated mononuclear cells and congestion and are occasionally necrotic. Escherichia coli was isolated from the lung, spleen and kidney. The result of antibiotic sensitivity test of the isolated organism was also described.

• 대한수의학회지
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• 제38권3호
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• pp.600-605
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• 1998

춘천지역에서 포획한 한국 야생랫드(시궁쥐)에서 Capillaria hepatica에 자연감염된 예를 보고한다. Capillaria hepatica의 충란이 포획된 68마리의 랫드중 17마리에서 발견되었다. Capillaria에 감염된 랫드의 간장은 충란과 함께 림프구, 단핵구, 호산구의 침윤이 관찰되었고 심한 괴사소견을 보였다. 또한 섬유화, 출혈 hemosiderin의 침착이 뚜렷하게 관찰되었다. 최근 국내에서 자연에서 채집된 랫드의 Capillaria hepatica의 감염을 보고한 자료가 없는 것으로 미루어 Capillaria hepatica의 숙주감염을 파악하는 자료로 활용될 수 있을 것이다.