• 한국생물정보학회:학술대회논문집
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• 한국생물정보시스템생물학회 2003년도 제2차 연례학술대회 발표논문집
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• pp.107-113
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• 2003

이 논문에서는 ER 시그날 시퀀스 서열의 존재 여부와 단백질에의 알파헬릭스 형태의 막횡단 부위를 예측하는 통합시스템을 개발하였다. 기존의 시스템과 달리 이 두 가지 예측을 하나의 통합된 시스템에서 수행하여 예측의 정확성을 높였다. 또한 인터넷에서 이용이 가능하도록 웹 서버(http://dblab.sejong.ac.kr/pass/index.html)를 구현하였다.

• 한국공작기계학회:학술대회논문집
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• 한국공작기계학회 2001년도 추계학술대회(한국공작기계학회)
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• pp.399-406
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• 2001

This study describes the geometric characteristic and the 5-axis machining method of end mill body with insert tip. The geometry of end mill body is consisted of the flute part and the insert tip part. Thus, this study defines the flute part as ruled surface with constant helix angle and the insert tip part as rectangular plane on general direction. The geometric algorithm and the 5-axis NC part program were calculated by our programmed software and a sampled end mill body was machined on 5-axis machining center equipped with two index tables. The machined end mill body with insert tip was very agreeable to the designed end mill body with insert tip. Thus, the method proposed in this study may be very useful for the machining of end mill body with insert tip.

• 한국공작기계학회논문집
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• 제11권6호
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• pp.1-9
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• 2002

This study describes the geometric characteristics and the 5-axis machining method in order to make end mill cutter coming with insert tips. End mill geometry is consisted of flute part and insert tip part. Flute part modeled by using ruled surfaces with constant helix angle, and insert tip part modeled by rectangular planes containing tapped hole of specified direction in its center. In this study, the modeled insert tip part considered both of a radial rake angle and a axial rake angle, because they were important cutting conditions. In order to machining the virtual end mill defined from geometric characteristics, we programmed a special software to machining the end mill considered in this study. This software can generate NC-codes about following processes, end milling or ball end milling of flute part end milling of rectangular plane, centering of hole, drilling of hole, and tapping of hole. Ant sampled end mills were modeled and machined on 5-axis CNC machining center with two index tables. Since machined end mills were very agreeable to designed end mills, we saw that the method proposed in this study can be very useful for manufacturing of end mill body with insert tip.

• Food Science and Biotechnology
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• 제15권3호
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• pp.418-423
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• 2006

Egg white powders (EWPs) were produced after pH adjustment (PH 6-9) of fresh egg white, followed by spray-drying, and foaming and gelling properties of EWPs were examined. EWP produced after pH adjustment to 6.5 (EWP-6.5) resulted in significantly higher foaming ability and gel hardness than control and other pH-adjusted EWP. Significant increases in surface -SH content and surface hydrophobicity of EWP-6.5 coincided with improved foaming ability and gel hardness. Significantly higher consistency index for reconstituted EWP-6.5 indicates unfolding of egg white protein was substantially increased in EWP-6.5. Decreased a-helix content in EWP-6.5 was confirmed by circular dichroism spectral analysis. These results indicate pH adjustment prior to spray-drying leads to structural changes in egg white proteins, significantly affecting major functionalities of EWP.

• Journal of Contemporary Eastern Asia
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• 제20권2호
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• pp.63-84
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• 2021

The present study was conducted to understand the turmoil effects of COVID-19 pandemic on the Malaysian stock market during the different periods of the Movement Control Order (MCO). The present study was based on the secondary data extracted from the DataStream and Bloomberg from 2nd January 2020 to 29th May 2020 to evaluate the effects of COVID-19 pandemic on the Malaysian stock market. The findings suggested that during the different periods of the Movement Control Order (MCO) from the 1st January to 29th May 2020, the COVID-19 pandemic adversely affected the performance of KLCI index and all sectoral indices. The weakest performance indices were energy, property, and finance while the least affected indices were healthcare, technology, telecommunications, and media. This paper provides a review of the impacts of COVID-19 pandemic on the Malaysian stock market throughout the different periods of MCO.

• Asian-Australasian Journal of Animal Sciences
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• 제32권10호
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• pp.1611-1620
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• 2019

Objective: The aim was to investigate the influence of ultrasound and adenosine 5'-monophosphate (AMP) marination (UAMP) on tenderness and structure of myofibrillar proteins of beef. Methods: Five groups, the untreated meat (Control), deionized water marination (DW), ultrasound followed by DW (UDW), AMP marination (AMP), and ultrasound followed by AMP (UAMP) were studied. Myofibrillar fragmentation, cooking loss, shear force, thermograms, histological observation of meats and myofibrillar proteins properties were investigated in these different treatments. Results: The results showed that UAMP significantly increased myofibrillar fragmentation index from 152 (Control), 231 (AMP), and 307 (UDW) to 355 (p<0.05), respectively. The lowest cooking loss, shear force and peak denaturation temperature were observed in UAMP. In histological observation, UDW and UAMP had more fragmented muscular bundles than the others. Furthermore, a drastic increase in ${\alpha}$-helix and decrease in ${\beta}$-sheet of myofibrillar proteins was observed in UAMP, implying the disaggregation of protein samples. The synchronous fluorescence spectra of myofibrillar proteins in UAMP suggested the combination of ultrasound and AMP could accelerate the unfolding molecular structure and destroying hydrophobic interactions. The results of circular dichroism and synchronous fluorescence spectra for myofibrillar proteins coincided with the microstructures of beef. Conclusion: The results indicate that ultrasound combined with AMP improved meat tenderness not only by disruption in muscle integrity, increasing water retention, but also altering their spatial structure of myofibrillar proteins.

• 대한수학회보
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• 제50권4호
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• pp.1109-1126
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• 2013

Let $\mathbb{M}^3_q(c)$ denote the 3-dimensional space form of index $q=0,1$, and constant curvature $c{\neq}0$. A curve ${\alpha}$ immersed in $\mathbb{M}^3_q(c)$ is said to be a Bertrand curve if there exists another curve ${\beta}$ and a one-to-one correspondence between ${\alpha}$ and ${\beta}$ such that both curves have common principal normal geodesics at corresponding points. We obtain characterizations for both the cases of non-null curves and null curves. For non-null curves our theorem formally agrees with the classical one: non-null Bertrand curves in $\mathbb{M}^3_q(c)$ correspond with curves for which there exist two constants ${\lambda}{\neq}0$ and ${\mu}$ such that ${\lambda}{\kappa}+{\mu}{\tau}=1$, where ${\kappa}$ and ${\tau}$ stand for the curvature and torsion of the curve. As a consequence, non-null helices in $\mathbb{M}^3_q(c)$ are the only twisted curves in $\mathbb{M}^3_q(c)$ having infinite non-null Bertrand conjugate curves. In the case of null curves in the 3-dimensional Lorentzian space forms, we show that a null curve is a Bertrand curve if and only if it has non-zero constant second Frenet curvature. In the particular case where null curves are parametrized by the pseudo-arc length parameter, null helices are the only null Bertrand curves.

• KSBB Journal
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• 제28권6호
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• pp.356-365
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• 2013

The novel Aloe gels were prepared with dewatering and impregnation by soaking (DIS) processing of Aloe vera leaf slice at four different temperatures (25, 35, 45 and $55^{\circ}C$), using dehydration solution of 40% (w/v) polyethylene glycol (PEG4000). The PEG-impregnation to Aloe vera leaf slice during DIS was observed depending on immersion temperature, and the PEG-impregnated Aloe vera gel (PEG-i-AVG) obtained was characterized using $^1H$ NMR, FT-IR, GPC, XRD and TGA. The PEG-i-AVG had the higher levels of Aloe bioactives (glucomannan and O-acetyl contents) and better quality indices by $^1H$ NMR and FT-IR spectroscopy than those of native Aloe gel. Also, the obtained Aloe gel maintained the bimodal patterns in higher molecular weight region by GPC indicating no degradation of polysaccharide from native Aloe gel. The result observed by SEM confirmed a surface modification by forming the porous structure, and TGA result exhibited better thermal stability than that of native Aloe gel. XRD result revealed that the crystalline structure in Aloe gel was led by incorporation of PEG. Significant decrease of %insolubility and high enhancement of water solubility index were observed, respectively, and highly ordered conformation such as a helix structure was also indicated by Congo red reaction. We concluded that the modification effect for enhancing function of native Aloe gel was successfully obtained by DIS process using PEG as a dehydrating agent. These results suggested that this DIS process had a high potential for developing a new minimally processed product from Aloe vera leaf.

• 대한두경부종양학회지
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• 제18권1호
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• pp.11-17
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• 2002

Objectives: Expression of HMGI(Y), a nucleoprotein that binds to A/T rich sequences in the minor groove of the DNA helix, is observed in neoplastically transformed cells but not in normal cells. We have analyzed HMGI(Y), p53 expression and Ki-67 labelling index in squamous cell carcinomas of the head and neck, and evaluated its clinicopathologic significance. Materials and Methods: 40 cases of squamous cell carcinoma of the head and neck were entered on the study of immunohistochemical stains for HMGI(Y), p53 and Ki-67. We analyzed the relationship between HMGI(Y), p53, Ki-67 expression and age, sex, primary tumor site, stage, survival rate, recurrence. Results: HMGI(Y) expression evidenced by immunohistochemical staining was observed in 35 of 40 (87.5%) squamous cell carcinoma of the head and neck. But no significant correlation was observed between HMGI(Y) expression and other clinical factors such as primary site, tumor stage, differenciation, cervical lymph node, metastasis, recurrence and immunohistochemical status of p53. The Ki-67 labelling index was significantly correlated with recurrence and HMGI(Y) expression (p<0.05). Conclusion: This results suggest the Ki-67 is a good prognostic factor and the HMGI(Y) expression plays some roles in carcinogenesis and cellular proliferation of squamous cell carcinoma of the head and neck. HMGI(Y) gene can be used as a cancer marker, the correlation between the gene expression and the prognosis of the cancer patient should be proved in the future studies.