• Tuberculosis and Respiratory Diseases
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• v.44 no.6
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• pp.1343-1352
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• 1997

Background : Heat-treated cells are known to be protected from lysis by TNF, which is considered to play a central role in the pathogenesis of sepsis-induced acute lung injury. The objective of the study was to investigate the effect of heat shock response by heat-pretreatment on the acute lung injury of the rats induced by intratracheally administered TNF-$\alpha$, Methods : We intratracheally instilled either saline or TNF (R&D, 500ng) with and without heat pretreatment in Sprague-Dawley rats weighing 250~350 g. The heated rats were raised their rectal temperature to $41^{\circ}C$ and was maintained thereafter for 13 minutes at 18 h before intratracheal administration of saline or TNF. After 5 h of intratracheal treatment, lung leak, lung myeloperoxidase activity (MPO) and heat shock proteins were measured in rats. Lung leak index was defined as counts per minute of $I^{25}$ in the right lung divided by counts per minutes of $I^{25}$ in 1.0 ml of blood. All data are expressed as means ${\pm}$SE. Results : There is no difference in acute lung leak index ($0.099{\pm}0.024$ vs $0.123{\pm}0.005$) among the rats given saline intratracheally with and without heat pretreatment, but MPO activity showed a decreased tendency in heat-pretreated rats ($4.58{\pm}0.79\;U/g$) compared with heat-unpretreated rats ($7.32{\pm}0.97\;U/g$) (P=0.064). Rats administered TNF intratracheally with heat-pretreatment had decreased lung leak index ($0.137{\pm}0.012$) and lung MPO activity ($5.51{\pm}1.04\;U/g$) compared with those of heat-unpretreated and TNF-administered rats ($0.186{\pm}0.016$, $14.34{\pm}1.22\;U/g$) (P<0.05 in each). There were no significant difference of lung leak index and MPO activity between TNF-treated rats with heat-pretreatment and saline-treated rats with and without heat-pretreatment. Conclusion : The heat shock response attenuated neutrophil recruitment and acute lung leak induced by intratracheal instillation of TNF-in rats.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.5 no.3
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• pp.217-225
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• 1993

Nonflammable mixtures of flammable and nonflammable refrigerants are possible as substitute refrigerants for use in domestic heat pumps and refrigerators. Refrigerant leakage from such a system is of paramount concern since it is possible that the resulting mixture composition remaining in system will reside in the flammable range. This paper presents a simulation of a leakage process of refrigerant mixtures. Idealized cases of isothermal leakage process are considered in this study representing a slow leak. Simulation is performed for selected composition of binary and ternary refrigerant mixture; R-32/134a and R-32/125/134a. Mixture compositions with respect to percentage leak of original charge are presented. In isothermal leakage process, both vapor and liquid compositions of more volatile refrigerant decrease during vapor and liquid leak, but the total composition of this component decreases during vapor leak and increases during liquid leak. Vapor and liquid compositions are determined depending on the vapor-liquid equilibrium relation of the refrigerant mixture. The refrigerant mixture left in the system can go to a nonflammable direction relying on which component in the mixture is flammable.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.19 no.10
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• pp.687-694
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• 2007

Cycle simulation is peformed for two types of the desiccant cooling system incorporating a regenerative evaporative cooler. The cooling capacity and COP are evaluated at various effectiveness values of the regenerative evaporative cooler, the desiccant rotor and the sensible heat exchanger. As either of the effectiveness of the regenerative evaporative cooler or the humidity effectiveness of the desiccant rotor increases, both the cooling capacity and COP increase, but the enthalpy leak ratio gives the opposite effect on the system performance. It is found that COP of cycle A mainly depends on the humidity effectiveness of the desiccant rotor, while for cycle B enthalpy leak ratio of desiccant rotor has the major impact on COP. The effect of the sensible heat exchanger on the cooling capacity is small about 1/10 compared with those of other components.

• Transactions of the Korean hydrogen and new energy society
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• v.10 no.3
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• pp.151-157
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• 1999

The development of hydrogen vehicles has been actively progressed in the developed countries such as U. S., Japan and Germany. The most important technology of using hydrogen fuel is to develope a compatible storage tank with respect to the fossil fuel tank. Among many storage methods, the liquid hydrogen is the most desirable state because of the lowest volume and weight. The metal hydride tank is too heavy and the compressed hydrogen tank is too bulky. Because of these reasons, it is the principal purpose to analyze the theoretical heat transfer for designing and manufacturing an actual $LH_2$ tank. The insulation methods of the room between inner and outer vessel are non-vacuum, vacuum, vacuum with MLI(Multi-Layer Insulation). According to the results of the numerically calculated heat leak through the walls of the $LH_2$ tank, the vacuum insulated tank has 20 times and the MLI tank has 5616 times less heat leak than the non-vacuum tank.

• Journal of Mechanical Science and Technology
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• v.19 no.5
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• pp.1206-1215
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• 2005

The thermal stratification phenomena, frequently occurring in the component of nuclear power plant system such as pressurizer surge line, steam generator inlet nozzle, safety injection system (SIS), and chemical and volume control system (CVCS), can cause through-wall cracks, thermal fatigue, unexpected piping displacement and dislocation, and pipe support damage. The phenomenon is one of the unaccounted load in the design stage. However, the load have been found to be serious as nuclear power plant operation experience accumulates. In particular, the thermal stratification by the turbulent penetration or valve leak in the SIS and SCS pipe line can lead these safety systems to failure by the thermal fatigue. Therefore in this study an 1/10 scaledowned experimental rig had been designed and installed. And a series of experimental works had been executed to measure the temperature distribution (thermal stratification) in these systems by the turbulent penetration, valve leak, and heat transfer through valve. The results provide very valuable informations such as turbulent penetration depth, the possibility of thermal stratification by the heat transfer through valve, etc. Also the results are expected to be useful to understand the thermal stratification in these systems, establish the thermal strati­fication criteria and validate the calculation results by CFD Codes such as Fluent, Phenix, CFX.

• Journal of the Korean Society of Safety
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• v.14 no.4
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• pp.78-84
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• 1999

A compact air-preheating type heat exchanger was developed and tested for the ultra-high temperature heat recovery applications. For the direct use of exhaust gases up to $1200^{\circ}C$, the heat exchanger adopted a ceramic core with high strength and low thermal expansion coefficient less than $1{\times}10^{-6}^{\circ}C^{-1}$. The ceramic core was fabricated by special extrusion and bonding techniques. To minimize thermal stresses in the core, spring-loaded sealing mechanism was designed and successfully installed. 1-pass air flow scheme was adopted for the compactness and cost-savings. The pressure test for the ceramic core showed no failure under 35 kPa and less than 3% leak under 7 kPa. Flue gas simulation system was developed to investigate the performance of the heat exchanger. The test results showed normal operations of the heat exchanger up to $1200^{\circ}C$ of exhaust gases and relatively high heat recovery efficiencies of 31～39% depending upon exhaust gas temperatures..

• Progress in Superconductivity and Cryogenics
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• v.7 no.3
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• pp.43-46
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• 2005

A Protomodel Space Infrared Cryogenic System (PSICS) cooled by a stirling cryocooler was designed. The PSICS has an IR sensor inside a cold box which is cooled by a stilting cryocooler with refrigeration capacity of 500mw at 80K in a vacuum vessel. It is important to minimize heat load for reducing background thermal noise. In order to design the cryogenic system of low heat load and to reduce heat load, we did several numerical analyses and tested using boil-off calorimetry with liquid nitrogen to measure the heat leak of the system. In this paper, we present the results obtained by thermal analysis and heat load measurement for designing the PSICS.

• Proceedings of the Korea Institute of Applied Superconductivity and Cryogenics Conference
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• 2003.10a
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• pp.328-331
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• 2003

In this study, the experimental study based on calorimetry for terminal cryostat has been performed and evaluated. The experiments performed here were divided into two types, those are test without and with current lead. The former is intended for the evaluation of feasibility and precision of our calorimetry, the later for the application to terminal cryostat of our study. As a result, it was found that the calorimetry performed in this study could predict well the heat transfer rate into the terminal cryostat.

• Fire Protection Technology
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• s.11
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• pp.13-22
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• 1991

To understand electrical fire, the cause of it is classified into overcurrent, short circuit, leak, joint, overheat, accumulation of heat, spark, deterioration of insulation, static electricity, and lightning etc. and explained. And then by the precautions to it, proposed to the improvement of electric products, the completeness of safecty management and the use of alarm systems.

• Journal of the Korean Society for Nondestructive Testing
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• v.30 no.2
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• pp.110-115
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• 2010

This study was conducted to estimate the feasibility using thermal image measurement that is applicable to internal leak diagnosis for the power plant valve. Abnormal heating of valve surface associated with high temperature steam f10w toward valve outlet side in the condition of low temperature is a primary indicator of leakage problems in high temperature and pressure valves. Thermal imaging enables to see the invisible thermal radiation that may portend impending damage before their condition becomes critical. When steam flow in valve outlet side in the condition of low temperature is converted into heat transmitted through the valve body due to the internal leakage in valve. The existence of abnormally increasable leakage rate in the valve will result in abnormally high levels of heat to be generated that can be quickly identified with a thermal image avoiding energy loss or damage of valve component. From the experimental results, it was suggested that the thermal image measurement could be an effective way to precisely diagnose and evaluate internal leak situation of valve.