• Journal of Embryo Transfer
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• v.22 no.1
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• pp.33-37
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• 2007

A 2 years old female beagle dog was examined because of the vaginal discharge and vaginal swelling at 7th day after mating. Abdominal ultrasonography revealed multiple follicular cysts on both ovaries. Also, the ratio of superficial cells was above 90% based on vaginal cytology. She was still in standing heat, with the tail deflected up and flagging when a male sniffed the vulva and attempted to mount. The dog was diagnosed with multiple follicular cysts by vaginal cytology, clinical signs and ultrasonography. The dog was treated with GnRH $50{\mu}g$ injection by intramuscularly. The sizes of the cysts were decreased two weeks after GnRH treatment, and then the dog delivered an offspring at 68th day after last mating. To confirm the stage of estrous cycle, we performed hormone analyses, retrospectively $Estradiol-17{\beta}$ concentration was 78pg/ml at diagnosis. Progesterone concentration was 6.9ng/ml at the last mating, and 66.9ng/ml at diagnosis. Therefore, we confirmed that follicular cysts was observed during diestrous stage in a beagle dog.

• Asian-Australasian Journal of Animal Sciences
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• v.12 no.2
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• pp.174-179
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• 1999

The effect of a chronic inflammation (cell-mediated immune response) on energy metabolism and growth performance was assessed in weanling piglets. Twenty four barrows of 4 wk of age were assigned to one of two immunization treatments : Control group [CON: immunized with Incomplete Freund's Adjuvant (lFA)] or Immunization group [IMMU: immunized with Complete Freund's Adjuvant (CFA)]. On d0, piglets were weaned and subcutaneously immunized at the medial side of the femur with 2 ml of IFA or CFA, respectively. Energy and nitrogen balances were measured per group during 13-d balance period, and total $(HP_{tot})$, activity-related ($(HP_{act})$) and non-activity-related $(HP_{cor})$ heat production were determined every 9-min by indirect calorimetry. Ig total titers to Mycobacterium butyricum, which is present in CFA, were higher (p<0.01) in IMMU than in CON on d13 (2.5 vs 1.8) and d20 (2.9 vs 1.8) after immunization. There were no differences (p>0.10) between treatments in rectal temperature, performance, feed intake, and availability and partitioning of energy during the balance period. Average daily feed intake was numerically higher in IMMU than in CON (0.34 vs 0.32 kg/d), but there was no difference (p>0.10) in metabolizability of the dietary energy between treatments. $HP_{act}/HP_{tot}$ was 16.24 and 16.89%, and retained energy was 251 and 268 $268\;kJ{\cdot}kg^{0.75}{\cdot}d^{-1}$ for CON and IMMU, respectively. Numerically, maintenance requirement of IMMU was even lower than that of CON $(419\;vs\;427\;kJ{\cdot}kg^{0.75}{\cdot}d^{-1})$. The present study suggests that a chronic inflammation has no effect on energy metabolism and growth performance, in spite of the difference in systemic antibody responses. The reason was considered to be due to locally induced immune response, resulting from the possible encapsulation at the site of injection, and/or to a low systemic immune stress which is within a functionally acceptable physiological range for the piglets.

• Tunnel and Underground Space
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• v.24 no.4
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• pp.297-307
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• 2014

Cavern Thermal Energy Storage system stores thermal energy in caverns to recover industrial waste heat or avoid the sporadic characteristics of renewable-energy resources, and its advantages include high injection-and-extraction powers and the flexibility in selecting a storage medium. In the present study, the structural stability of rock mass pillar between these silo-type storage caverns was assessed using a coupled thermal-mechanical model in $FLAC^{3D}$. The results of numerical simulations showed that thermal stresses due to long-term storage depended on pillar width and had significant effect on the pillar stability. A sensitivity analysis of main factors indicated that the influence on the pillar stability increased in the order cavern depth < pillar width < in situ condition. It was suggested that two identical caverns should be separated by at least one diameter of the cavern and small-diameter shaft neighboring the cavern should be separated by more than half of the cavern diameter. Meanwhile, when the line of centers of two caverns was parallel to the direction of maximum horizontal principal stress, the shielding effect of the caverns could minimize an adverse effect caused by a large horizontal stress.

• Journal of Physiology & Pathology in Korean Medicine
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• v.17 no.2
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• pp.346-351
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• 2003

The current studies investigated the therapeutic effects of Ephedra sinica Stapf (ES) herb-acupuncture on the inflammatory responses of rat arthritic joint, which was induced by the intradermal injection of heat-killed Mycobacterium tuberculosis emulsified in squalene to the base of the tail. The measurements of body weight and articular index were exploited as the assessment methods addressing arthritic symptoms, and the expression profiles of cytokines such as TNF-α, IL-1β and IL-6 in the rat joint were analyzed using RT-PCR. The articular indexes of arthritic rats were significantly restored after the treatment with ES herb-acupuncture. Although the clinical symptoms of arthritic rats were apparently alleviated by the ES treatments, their body weights were not recovered. It maybe due to the weight-loss and energy enhancement effects of ES extracts. The expression of TNF-α, IL-1β and IL-6 genes, which were highly stimulated in the knee joints of arthritic rats, were restored to the levels of normal rats after the ES treatment. The therapeutic effect of ES herb-acupuncture was not observed in ES-treated, non-acupoint arthritic group as a sham control. The ES herb-acupuncture into an acupoint ST36 was found to be effective in alleviating the arthritic symptoms in adjuvant-induced arthritis rats as regards the body weight, joint appearance and the expression profiles of inflammatory cytokines.

• Nuclear Engineering and Technology
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• v.27 no.4
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• pp.470-482
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• 1995

The Ulchin 3&4, which are 2825 MWt PWRs, adopted Safety Depressurization System (SDS) to mitigate the beyond design basis event of Total Less of Feedwater(TLOFW). In this study the results and methodology of the analyses for the determination of SDS bleed capacity are discussed. The SDS design bleed capacity has been determined from the CEFLASH-4AS/REM simulation according to the following design criteria : 1) Each SDS flow path, in conjunction with one of two High Pressure Safety Injection (HPSI) pumps, is designed to have a sufficient capacity to prevent core uncovery if one SDS path is opened simultaneously with the opening of the Pressurizer Safety Valves (PSVs). 2) Both SDS bleed paths are designed to have sufficient total capacity with both HPSI pumps operating to prevent core uncovery if the Feed and Bleed (F&B) initiation is delayed up to thirty minutes from the time of the PSVs lift. To verify the results of CEFLASH-4AS/REM simulation a comparative analysis kas also been per-formed by more sophisticated computer code, RELAP5/MOD3. The TLOFW event without operator recovery and TLOFW event with F&B are analyzed. The predictions by the CEFLASH-4AS/REM of the transient too phase system behavior are in good qualitative and quantitative agreement with those by the RELAP5/MOD3 simulation. Both of the results of analyses by CEFLASH-4AS/REM and RELAP5/MOD3 have demonstrated that decay heat removal and core inventory make-up can be successfully accomplished by F&B operation during now event for the Ulchin 3&4.

• Proceedings of the Ginseng society Conference
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• 2002.10a
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• pp.55-65
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• 2002

Ginseng has been used as a key constituent in traditional medicine prescriptions for centuries. Other than its well-known anti-stress and adaptogenic properties, ginseng has also been shown to be very effective in treating age-related deterioration in metabolic and memory functions. Although it is generally believed that the saponin (GS) fraction of the ginseng root accounts for the bioactivity of ginseng, a direct demonstration on which ginsenoside does what is still generally lacking. In the past decade, our laboratory has endeavored to identify the active GS components involved in energy metabolism, memory, and anti-neurotoxicity. To examine the ergogenic effects of GS in enhancing aerobic capacity, rats were subjected to either severe cold ($40^{\circ}C$ under helium-oxygen, two hours) or exercise workload $(70\%\;VO_{2}max,$ to exhaustion). Acute systemic injection (i.p.) of ginseng GS (5-20 mg/kg) significantly elevated both the total and maximum heat production in rats and improved their cold tolerance. However, pretreating the animal with the optimal dose (10 mg/kg) of GS devoid of $Rg_1\;and\;Rb_1$ failed to elicit any beneficial effects in improving cold tolerance. This indicates that either $Rb_1\;and/or\;Rg_1$ may be essential in exemplifying the thermogenic effect of GS. Further studies showed that only pretreating the animals with $Rb_1(2.5-5\;mg/kg),\;but\;not\;Rg_l,$ resulted in an increase in thermogenesis and cold tolerance. In contrast to the acute effect of GS on cold tolerance, enhancement of exercise performance in rats was only observed after chronic treatment (4 days). Further, we were able to demonstrate that both $Rb_1\;and\;Rg_1$ are effective in enhancing aerobic endurance by exercise. To illustrate the beneficial effects of GS in learning and memory, a passive avoidance paradigm (shock prod) was used. Our results indicated that the scopolamineinduced amnesia can be significantly reversed by chronically treating (4 days) the rats with either $Rb_1\;or\;Rg_1$ (1.25 - 2.5 mg/kg). To further examine its underlying mechanisms, the effects of various GS on ${\beta}-amyloid-modulated$ acetylcholine (ACh) release from the hippocampal slices were examined. It was found that inclusion of $Rb_1$ (0.1 ${\mu}M$), but not $Rg_1$, can attenuate ${\beta}-amyloid-suppressed$ ACh release from the hippocampal slices. Our results demonstrated that $Rb_1\;and\;Rg_1$ are the key components involved in various beneficial effects of GS but they may elicit their effects through different mechanisms.

• Journal of the Korean Institute of Gas
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• v.25 no.5
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• pp.11-18
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• 2021

Since hydrogen has the lower minimum ignition energy than that of gasoline, hydrogen could be also appropriate for the IC engine systems. However, due to the low ignition energy, there might be a 'back-fire' and 'pre-ignition' problems with hydrogen SI(Spark-ignition) combustion. In this research, cooling effects of intake gas mixture on the improvement of the maximum power output were evaluated in a 2.4 L SI engine. There were two ways to cool intake gas mixtures. The first one was cooling intake fresh air by adjusting inter-cooler system after turbocharger. The other one was cooling hydrogen fuel before supplying by using heat ex-changer. Cooling hydrogen was performed under natural aspired condition. The result showed that cooling fresh air from 40 ℃ to 20~30 ℃ improved the maximum brake power up to 6.5~8.6 % and cooling hydrogen fuel as -6 ℃ enhanced the maximum brake power likewise.

• Resources Recycling
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• v.28 no.4
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• pp.30-36
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• 2019

In this study, Li powder was recovered from the by-product of LNO ($Li_2NiO_2$) process, which is the positive electrode active material of waste lithium ion battery, through the $CO_2$ thermal reaction process. In the process of recovering Li powder, the $CO_2$ injection amount is 300 cc/min. The $Li_2NiO_2$ award was phase-separated into the $Li_2CO_3$ phase and the NiO phase by holding at $600^{\circ}C$ for 1 min. After this, the collected sample:distilled water = 1:50 weight ratio, and after leaching, the solution was subjected to vacuum filtration to recover $Li_2CO_3$ from the solution, and the NiO powder was recovered. In order to increase the purity of Ni, it was maintained in $H_2$ atmosphere for 3 hours to reduce NiO to Ni. Through the above-mentioned steps, the purity of Li was 2290 ppm and the recovery was 92.74% from the solution, and Ni was finally produced 90.1% purity, 92.6% recovery.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.6
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• pp.460-468
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• 2021

This study investigated the enhanced combustion efficiency of an "air-cooled combustion system" with single F.D. fan, and performed a numerical analysis for the operation and design conditions to increase the combustion efficiency. The combustion efficiency in an actual combustor was compared before and after the structure modification. Numerical analysis for application of a single fan revealed the difficulty of forming a turbulence for circular combustion conditions. This is because the supply ratio of combustion air supplied into 2 flow paths becomes irregular in the combustion furnace due to a change in friction force and pressure in each flow path. Subsequently, two methods of supplying air into the combustion furnace were analyzed numerically to obtain the optimal combustion conditions of an air-cooled combustion system. The first method involved injecting the preheated combustion air after a 180~360 degree rotation from the outer wall, whereas in the second method, the combustion air was injected into the combustion furnace in a tangential direction after primary heat exchange outside the combustion furnace, by applying a rotatable vane structure in the combustion furnace. Results reveal that application of a single F.D. fan to the air injection into a rotatable combustion furnace is desirable for optimization of the combustion conditions for applying a duct structure having a dual cooling wall for the cooling of the outer wall of the combustion furnace, and for maintaining perfect mixing in the combustion furnace. We therefore confirmed enhanced combustion efficiency by comparing the actual combustion efficiency before and after structure modification.

• Journal of Korean Society of Water Science and Technology
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• v.26 no.6
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• pp.99-107
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• 2018

This research has developed a high temperature steam cleaning technology using a ceramic membrane with durability against temperature and pressure conditions. In steam cleaning, steam of $120^{\circ}C$ is injected into the ceramic membrane to induce pyrolysis by the endothermic reaction to remove fouling from the membrane. The water quality of raw water was adjusted to turbidity 10, 25 NTU and DOC 2.5 mg/L, and the membrane was uniformly fouled by constant pressure operation at 100, 200, and 300 kPa. Physical backwashing was performed with water and air at a pressure of 500 kPa and steam at $120^{\circ}C$ was injected for 0 to 5 minutes. As the turbidity concentration and the operating pressure increased, the flux decreased by 0.7 to 14.4%. It is confirmed that 10.7 to 53.8% recovery is possible than physical cleaning at the injection of steam for 3 minutes, so it is considered that the steam cleaning of the ceramic membrane is effective. Compared with CEB after NaOCl (300 mg/L) filtration at 25 NTU and 300 kPa of turbidity, the steam cleaning result for 3 minutes was similar to 46.7% of CEB for 3 hours. It has been confirmed that steam cleaning is suitable for a ceramic membrane having excellent heat resistance against high temperature. It was considered to have better cleaning efficiency as compared with general physical backwashing.