• Journal of the Ergonomics Society of Korea
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• v.29 no.6
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• pp.915-924
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• 2010

Muscular strength in the elderly is important factors deciding on functional state in daily lives, and functional state shows a health condition. Resistance training to prevent loss of muscle mass and muscle fiber atrophy due to aging can increase muscle mass and strength. Recently, resistance training to improve muscular strength and endurance has been actively researched. Resistance training increases activities of daily living and ability of the elderly, which makes healthy senescent. ADL/IADL is suitable for measuring health condition of the elderly. In this study, target muscles of resistance training were chosen through a correlation analysis between ADLs and elementary motion, and we presented a procedure to select target muscles and exercise equipments. This procedure consist of a survey method that were described detailed motion of ADL/IADL. So we should be to extract resistance training machine to improve functions of regarding fundamental motion. Result of study may improve daily life activities of the elderly through objectives and scientific approaches. Furthermore, it will be helpful to studies about various fields of the elderly.

• BMB Reports
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• v.50 no.5
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• pp.269-274
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• 2017

The biological activities of macrophage migration inhibitory factor (MIF) might be mediated through a classical receptor-mediated or non-classical endocytic pathway. JAB1 (C-Jun activation domain-binding protein-1) promotes the degradation of the tumor suppressor, p53, and the cyclin-dependent kinase inhibitor, p27. When MIF and JAB1 are bound to each other in various intracellular sites, MIF inhibits the positive regulatory effects of JAB1 on the activity of AP-1. The intestinal parasite, Anisakis simplex, has an immunomodulatory effect. The molecular mechanism of action of As-MIF and human JAB1 are poorly understood. In this study, As-MIF and hJAB1 were expressed and purified with high solubility. The structure of As-MIF and hJAB1 interaction was modeled by homology modeling based on the structure of Ace-MIF. This study provides evidence indicating that the MIF domain of As-MIF interacts directly with the MPN domain of hJAB1, and four structure-based mutants of As-MIF and hJAB1 disrupt the As-MIF-hJAB1 interaction.

• Korean Journal of Health Education and Promotion
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• v.27 no.2
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• pp.69-78
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• 2010

Objectives: The purpose of this study was to investigate the basic grounds for the policies of health promotion on the elderly by analyzing lifestyle. Methods: This study recruited 500 seniors aged over 65 years participating in exercise programs for the elderly provided by four branch offices of NHIC in Daegu. Results: 'Ideal type' was a group thinking that exercise programs for the elderly made their life healthy and energetic and living a happy life and 'social type' was a group answering that they helped to manage their health condition and to relieve stress and activated relationship with family members and friends to gain self-confidence. ‘Passive type’ and 'lethargic type’ said that the programs did not influence their life overall. Conclusion: Entrance into an aging society has changed values of the elderly. Their lifestyle becomes various and the effect of exercise programs for the elderly was also different according their lifestyle. Therefore, exercise programs considering lifestyles of the elderly will maximize their effect.

• Journal of Preventive Medicine and Public Health
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• v.46 no.sup1
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• pp.22-27
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• 2013

The purpose of this study was to examine the beneficial effects of a new cognitive intervention program designed for the care and prevention of dementia, namely Learning Therapy. The training program used systematized basic problems in arithmetic and Japanese language as training tasks. In study 1, 16 individuals in the experimental group and 16 in the control group were recruited from a nursing home. In both groups, all individuals were clinically diagnosed with senile dementia of the Alzheimer type. In study 2, we performed a single-blind, randomized controlled trial in our cognitive intervention program of 124 community-dwelling seniors. In both studies, the daily training program using reading and arithmetic tasks was carried out approximately 5 days a week, for 15 to 20 minutes a day in the intervention groups. Neuropsychological measures were determined simultaneously in the groups both prior to and after six months of the intervention. The results of our investigations indicate that our cognitive intervention using reading and arithmetic problems demonstrated a transfer effect and they provide convincing evidence that cognitive training maintains and improves the cognitive functions of dementia patients and healthy seniors.

• Radioisotope journal
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• v.21 no.4
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• pp.38-45
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• 2006

A new herbal composition. HemoHIM, was developed using irradiated animal models and was successfully applied as an immune-improving agent. In a view that the protection and recovery of immune, hematopoietic and self-renewal tissues are essential for radioprotective agents, HemoHIM was developed based on a novel combination of three edible herbs (Angelica Radix, Cnidii Rhizoma. Paeonin Radix) that meet all those requirements. HemoHIM significantly protected the immune and hematopoietic system and enhanced their recovery in y-irradiated mice. For the application of HemoHIM as a health functional food and a supplementary agent for the cancer patients, the efficacy of HemoHIM to improve the immune functions was further evaluated in immune-depressed animals and humans. Animal studies demonstrated that HemoHIM significantly improved the immune functions in cyclophosphamide-treated mice, aged mice, and dexamethasone-treated mice. In human studies, HemoHIM enhanced the immune activity and cytokine secretion in sub-healthy volunteers, and alleviated the severe leukocyre depression in cancer patients during radiation and chemotherapy. Based on these results, HemoHIM was approved by Korea FDA as a material of health functional food for immune function improvement and will be commercially available soon. This case of HemoHIM research and development suggested that irradiated animals can be good models for biological degenerations such as immune depression, self-renewal tissue damage, and aging for the development of biological modulators.

• Research in Community and Public Health Nursing
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• v.30 no.2
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• pp.234-242
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• 2019

Purpose: This study tries to comprehend older adults' perspectives of community supports and health services in a South Korean city and identify important sociodemographic and health characteristics that affect their perspectives. Methods: 166 older adults were involved in this cross-sectional study. Questions on background characteristics and community supports and health services criteria (categorized as service accessibility, offer of services, voluntary support, or emergency care planning) based upon the WHO's Age-Friendly Cities Guide were used. The data were analyzed using paired and independent t-tests, one-way ANOVA, and hierarchical multiple regression analyses. Results: emergency care planning was rated as the most important by the participants (mean age=76.24 years, 22.9% male), while its current level of performance was lowly appraised (p<.001). The rated importance for each category differed based on individual characteristics. Depression (p=.016), older age (p=.012), and restricted network type (p=.039) were significantly related to ascribing a higher degree of importance to community services. Conclusion: Community initiatives are warranted to optimize emergency care for older adults. This planning must be based on the unique characteristics of older adults in coordination with supportive resources. In addition, comprehensive assessments are warranted before implementing action plans to ensure that the multi-dimensional problems of older adults are incorporated.

• Journal of Wellbeing Management and Applied Psychology
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• v.4 no.1
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• pp.27-34
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• 2021

Purpose: The number of people with disabilities and the elderly over 65 years of age is gradually increasing due to physical disabilities and social aging. Their typical physical disorders or chronic diseases include low back pain, sciatic pain, arthritis, and musculoskeletal systems such as discs. The average prevalence of disease is 78%. These are various physical obstacles and hindrances in daily life. Research design, data and methodology: From August 6, 2019 to September 24, 2019, the Senior Welfare Center in Gyeyang-gu, Incheon, operated a healthy body exercise and health education program for living health management. Results: The vascular health index using U-Bio pulse wave was relatively good at the first average of +7.4, but the second average of -6.3. This can be seen as a result of the combination of diet and lifestyle education along with the effect of corrective exercise. As a result of body shape measurement analysis, the number of persons requiring management with 3 or more body imbalances was found to be from 75% before to 62.5% afterwards. Conclusions: Exercise effect appears when exercise lasts for at least 10 weeks. Some performances were good, but there were limitations due to the operation of a short training period.

• Journal of Korean society of Dental Hygiene
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• v.21 no.1
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• pp.65-76
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• 2021

Objectives: In an aging society, the demand for dental medical institutions among the elderly is increasing. There will be an increased demand for high-quality oral health services. Therefore, the purpose of this study was to investigate factors influencing attitudes toward the elderly of Generation Z dental hygiene students. Methods: The participants in this study were 198 dental hygiene students. The survey was conducted from June 1 to 30, 2020, using a structured questionnaire. The questionnaire consisted of knowledge (24 items), attitude (20 items), and experience (11 items) of the elderly. The collection data were compared and analyzed using analysis of variance and multiple regression. Results: Factors influencing attitudes toward the elderly of dental hygiene students appeared positive in those with a lot of experience and higher knowledge of social area, in case of one grade. However, the attitude toward the elderly appears negative in those with a low knowledge of physical area. Conclusions: In order to improve Generation Z dental hygiene students' attitudes towards the elderly, it is necessary to develop a course related to the elderly and a program related to high-quality elderly contact experience opportunities. Socially, it is necessary to promote healthy elderly life through internet broadcasting and YouTube.

• PNF and Movement
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• v.9 no.4
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• pp.1-11
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• 2011

Purpose : This study is to identify the effect of a thera-band exercise program on the physical function of elderly women. Methods : The subjects included 54 elderly women who participated in the program at J Senior Welfare Center in Jeollabuk-do. They were divided into two groups, 30 elderly women of control group and 24 of experimental group. A thera-band exercise program was conducted to both groups for total eight weeks-three times a week with a 50-minute period. After/before the experiment, the following seven categories were estimated for each subject: cardiopulmonary endurance, lower extremity power, upper extremity power, muscle endurance, flexibility, equilibrium, and agility. Results : There was a significant increase on the physical function of all the subjects in the experimental group and the control one after the experiment. Furthermore, the experimental group showed more meaningful improvement than the control one. Conclusion : On the basis of these findings, the thera-band exercise program contributes the enhancement of physical function of elderly women. Thus, more various physical exercise program should be developed for healthy aging.

• Journal of Microbiology and Biotechnology
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• v.33 no.1
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• pp.135-141
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• 2023

Protection of skin cells from chronic infrared-A (IRA) irradiation is crucial for anti-photoaging of the skin. In this study, we investigated the protective activity of Rg3(S) and Rg3(S)-incorporated anionic soybean lecithin liposomes (Rg3/Lipo) with a size of approximately 150 nm against IRA-induced photodamage in human fibroblasts. The formulated Rg3/Lipo showed increased solubility in aqueous solution up to a concentration of 200 ㎍/ml, compared to free Rg3(S). In addition, Rg3/Lipo exhibited superior colloidal stability in aqueous solutions and biocompatibility for normal human dermal fibroblasts (NHDFs). After repeated IRA irradiation on NHDFs, elevated levels of cellular and mitochondrial reactive oxygen species (ROS) were greatly reduced by Rg3(S) and Rg3/Lipo. In addition, cells treated with Rg3/Lipo exhibited noticeably reduced apoptotic signals following IRA irradiation compared to untreated cells. Thus, considering aqueous solubility and cellular responses, Rg3/Lipo could serve as a promising infrared protector for healthy aging of skin cells.