• The Journal of Health Technology Assessment
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• v.6 no.2
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• pp.95-99
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• 2018

As technologies develop, the digital health sector is gradually expanding. Internationally, the global summit for Digital Health named Global Digital Health Partnership (GDHP) was launched in 2018. Many countries are participating in GDHP and share their policy experiences on digital health and find the ways to cooperate with participating countries (13 countries, including South Korea, and Hong Kong). This article reviewed the international trends in digital health policy environment and evidence assessment focusing on GDHP activities, and derived implications for health technology assessment of digital health. Consequently, to assess the intervention effects of digital health is very complex and the assessment should be considered multidimensional aspects (social, clinical, and technical). In addition the patient experience should be assessed qualitatively. Health technology assessment (HTA) should assess the effect of digital health policies to changes in health care systems resulting from the application of advanced technologies related to the 4th Industrial Revolution. Digital health is also related to new HTA, HTA of existing technologies, and R&D on the promising health technology. Therefore, it is necessary to review the trends of the technology's management policy consistently through the HTA of digital health.

• Asia-pacific Journal of Multimedia Services Convergent with Art, Humanities, and Sociology
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• v.7 no.10
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• pp.865-878
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• 2017

To realize the healthy life of human, mental, physical, and environmental factors must be managed continuously and stably. In order to manage human health, the 21st century healthcare field is essential ongoing interactions and convergence with ICT technologies. Such demands have created a convergence of technologies (fusion technology) in combination with the heterogeneous technologies. And, with the convergence of medical technology and ICT technologies, the development of personalized therapy environments is created. Advances in ICT-converged healthcare services are progressing due to the development of diverse wearable devices. Such ICT fusion system is exponentially increasing the complexity of the ICT convergence healthcare system and is resulting in various technical, institutional, environmental, and cultural issues. This study explores the status of developments in ICT healthcare technologies from the past to date, identifies major technology and policy issues to address these challenges. Finally it will recommend healthcare policies and a future road-map.

• Journal of Sensor Science and Technology
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• v.21 no.4
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• pp.241-248
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• 2012

Recently healthcare industry such as pharmaceutical, medical device and healthcare service technology is growing significantly. Mobile healthcare has attracted big attention due to IT convergence technology. Paradigm of healthcare has been changed from the 1st generation(communicable disease prevention) and the 2nd generation(treatment of disease due to extended life expectancy) to the 3rd generation(extended life expectancy due to prevention and control). In our study, we suggest the 3rd generation mobile healthcare system using Bluetooth based wearable ECG monitoring system and smart phone technology. The mobile healthcare system consists of wearable shirts with Bluetooth communication module, ECG sensor, battery, and mobile phone. The ECG data is obtained by a miniaturized sensor and the data is transferred to a mobile phone using Bluetooth communication. Then, user can monitor his/her own ECG signal on an application using Android in mobile phone. The Bluetooth communication device is used due to highly reliable data transmission property and the Bluetooth chip is embedded in every mobile phone. The wearable shirts with chest belt of Bluetooth ECG module is designed with a focus on convenience in the daily life of a wearer. The ECG signal evaluation software in Android based mobile phone is developed for the health check and the ECG signal variation is tested according to the activities of the wearer such as walking, climbing stairs, stand up and sit down, and so on.

• The Journal of Bigdata
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• v.3 no.1
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• pp.73-82
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• 2018

At the core of future medicine is the realization of Precision Medicine centered on individuals. For this, we need to have an open ecosystem that can view, manage and distribute healthcare data anytime, anywhere. However, since healthcare data deals with sensitive personal information, a significant level of reliability and security are required at the same time. In order to solve this problem, the healthcare industry is paying attention to the blockchain technology. Unlike the existing information communication infrastructure, which stores and manages transaction information in a central server, the block chain technology is a distributed operating network in which a data is distributed and managed by all users participating in the network. In this study, we not only discuss the technical and legal aspects necessary for demonstration of healthcare data distribution using blockchain technology but also introduce KOREN SDI Network-based Healthcare Big Data Distribution Demonstration Study. In addition, we discuss policy strategies for activating blockchain technology in healthcare.

• Korean Journal of Veterinary Research
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• v.45 no.4
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• pp.495-500
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• 2005

The nucleoside analogue gemcitabine (2', 2-difluorideoxycytide) is potential against a wide variety of solid tumors and considered to be one of the most active drugs in the treatment of non-small cell lung cancer (NSCLC). In this study, we investigated the signals of gemcitabine-induced apoptosis, especially in point of caspase pathway in A549. We exposed A549 cells to gemcitabine for dose/time dependent manner and the results showed that gemcitabine induced apoptotic cell death in a time/dose-dependent manner. We also treated to gemcitabine and Z-VAD-fmk as a pan-caspase inhibitor for 24 hours. Gemcitabine alone induced 35.3% cell death, and co-treatment with gemcitabine and Z-VAD-fmk induced 15.1% apoptotic cell death. Our results demonstrated that Z-VAD-fmk as a pan-caspase did not completely block the gemcitabine-induced apoptosis. Western blotting analysis showed that gemcitabine increased caspase-3, active caspase-8, p21 and p53 protein expressions in A549. Co-treatment with Z-VAD-fmk completely blocked caspase-3 and active caspase-8 protein expressions, but did not change the level of p21 and p53 protein expressions. Our data indicate that gemcitabine induced apoptosis through caspase-dependent and -independent pathways in A549.

• Fashion & Textile Research Journal
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• v.22 no.5
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• pp.607-616
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• 2020

Health care wearables are devices that are attached to or combined with the human body to improve the health care capabilities of the human body that can be safely and adjustable according to preference. This study provided direction for future research on healthcare wearables in the field of clothing science, considering trends observed in this field from 2010 to 2019. Over the last 10 years, 812 studies have been conducted on healthcare wearables in Korea. Research has increased significantly since 2015, with a large number of articles published in this field. The research for this study was broken down into the following categories: technology development, marketing analysis, and technology analysis. The results according to the research method demonstrated that development and production methods were used most frequently, followed by trend analysis, experiment and evaluation, and survey. An analysis of keywords in the articles studied revealed that device, healthcare, big data (biometric data and database), and healthcare convergence technologies were trending. Similarly, detailed research on healthcare wearable devices and related technologies was actively being conducted. However, focusing on fiber, textiles, design, and clothing articles, in relation to the field of clothing in healthcare wearables, only 81 articles were found on this topic (10.0%), which was low compared to other studies. Therefore, it was determined that more research on healthcare wearables is necessary in the field of clothing.

• The Journal of Korea Institute of Information, Electronics, and Communication Technology
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• v.7 no.1
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• pp.45-49
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• 2014

In this paper, we propose a secure and efficient RFID-based patient authentication protocol to not only authenticate patients' authenticity but also protect patients' personal medical informations for u-Healthcare environments. Since the proposed RFID-based patient authentication protocol provides strong security and efficiency, it can be used practically for patient authentication and personal medical information protection on the high technology medical environments such as u-Hospital and u-Healthcare.

• Journal of Service Research and Studies
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• v.2 no.2
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• pp.45-51
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• 2012

U-healthcare is real-time monitoring of personal biometric information using by portable devices, home network and information and communication technology based healthcare systems, and fused together automatically to overcome the constraints of time and space are connected with hospitals and doctors. As u-healthcare gives health service in anytime and anywhere, it becomes to be a new type of medical services in patients management and disease prevention. In this paper, recent changes in prevention-oriented care is analyzed in becoming early response for Healthcare Information System by requirements analysis for technology development trend. According to the healthcare system, PACS, OCS, EMR and emergency medical system, U-healthcare is presenting the design of a patient-centered integrated client system. As the relationship between the meaning of the terms is used in the ontology, information models in the system is providing a common vocabulary with various levels of formality. In this paper, we propose an ontology-based system for patient-centered services, including the concept of clustering to clustering the data to define the relationship between these ontologies for more systematic data.

• Journal of information and communication convergence engineering
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• v.10 no.4
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• pp.337-342
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• 2012

The medical industries are integrated with information technology with mobile devices and wireless communication. The advent of mobile healthcare systems can benefit patients and hospitals, by not only providing better quality of patient care, but also by reducing administrative and medical costs for both patients and hospitals. Security issues present an interesting research topic in wireless and pervasive healthcare networks. As information technology is developed, many organizations such as government agencies, public institutions, and corporations have employed an information system to enhance the efficiency of their work processes. For the past few years, healthcare organizations throughout the world have been adopting health information systems (HIS) based on the wireless network infrastructure. As a part of the wireless network, a mobile agent has been employed at a large scale in hospitals due to its outstanding mobility. Several vulnerabilities and security requirements related to mobile devices should be considered in implementing mobile services in the hospital environment. Secure authentication and protocols with a mobile agent for applying ubiquitous sensor networks in a healthcare system environment is proposed and analyzed in this paper.

• International Journal of Oral Biology
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• v.43 no.1
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• pp.1-3
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• 2018

Blockchain is at the center of attention recently and it is expected to have a huge impact on healthcare industry including dentistry as well. Blockchain is a fundamental technology behind Bitcoin and itis all about decentralization, security, reliability, and transparency. These characteristics of the technology empower it to disrupt the current healthcare industry in innumerable practices such as supply chain management in pharmaceuticals to prevent the counterfeited medicine, clinical trials to guarantee transparency, healthcare information exchanges or personal health record systems to ensure data integrity and interoperability, etc. It will surely revolutionize the way the current healthcare system works; from provider-oriented to patient-centered. Hence, it is time to seriously consider how we could be a part of this blockchain revolution in dentistry.