• Journal of Korean society of Dental Hygiene
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• v.6 no.4
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• pp.361-374
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• 2006

The purpose of this study was to obtain basic data for development of oral health educational program on the control of handicapped children at social welfare facilities. For this research, it was investigated by a survey on the actual condition of dental health of handicapped children, and simultaneously by analyzing the relationships between the realities of child's dental condition and parents and guardian's acknowledgments and managements with regard to the dental health of children. This survey was conducted 135 children and their guardians being 4 social welfare facilities in Ulsan metropolitan city. 1. The average of DT, MT, FT and DMFT index were 1.82, 0.01, 0.98 and 2.84 respectively. 2. Rolling Toothbrushing method was the highest response(58.5%) and 3 times per a day(77.0%). A proxy of toothbrushing was parents(39.2%) and teacher(60.8%). 3. Recognition routes of toothbrushing method were family(13.3%), school(43.7%) and dental chinic(42.2%). 4. The numer of times electromotion tooth brushing was the highest response in more than 4 times per a day. Toothbrushing after eating between meals was higher negative response(50.4%). The number of times visiting dental clinic was the highest response in more than 5 times during a year(51.9%).

• Proceedings of the Korean Society of Food Science and Nutrition Conference
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• 2004.11a
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• pp.17-23
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• 2004

Not all individuals respond identically, or at times in the same direction, to dietary interventions. These inconsistencies likely arise because of diet and genomic interactions (nutrigenomics effects). A host of factors may influence the response to bioactive food components including specific polymorphisms (nutrigenetic effect), DNA methylation patterns and other epigenomic factors (nutritional epigenomic effects), capacity to induce anuo. suppress specific mRNA expression and patterns (nutritional transcriptomics), the occurrence and activity of proteins (proteomic effects), and/or the dose and temporal changes in cellular small molecular weight compounds will not only provide clues about specificity in response to food components, but assist in the identification of surrogate tissues and biomarkers that can predict a response. While this 'discovery' phase is critical for defining mechanisms and targets, and thus those who will benefit most from intervention, its true usefulness depends on moving this understanding into 'development' (interventions for better prevention, detection, diagnosis, and treatment) and a 'delivery' phase where information is provided to those most in need. It is incumbent on those involved with food and nutrition to embrace the 'omics' that relate to nutrition when considering not only the nutritional value of foods and their food components, but also when addressing acceptability and safety. The future of 'Nutrigenomics and Health Promotion' depends on the ability of the scientific community to identity appropriate biomarkers and susceptibility variants, effective communications about the merits of such undertakings with the health care community and with consumers, and doing all of this within a responsible bioethical framework.

• Safety and Health at Work
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• v.12 no.4
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• pp.546-548
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• 2021

• Safety and Health at Work
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• v.13 no.1
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• pp.131-133
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• 2022

• Korean Journal of Occupational Health Nursing
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• v.26 no.4
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• pp.207-217
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• 2017

Purpose: This study aimed to evaluate the workplace response system (WRS) against infectious disasters (IDs) based on the response attitudes and capacity of occupational health nurses (OHNs) who worked during the 2015 Middle East Respiratory Syndrome (MERS) outbreak in South Korea. Methods: Fifty-one participants who had worked as OHNs at the time of the 2015 MERS outbreak were surveyed from November 20 to December 10, 2016. Data were collected using a self-report questionnaire and analyzed using descriptive statistics and McNemaer's test. Results: According to the survey results, the following were lacking in the WRS: a dedicated ID-response team, manuals, related education programs for OHNs, and health education programs for workers. Results also confirmed that workers were vulnerable to new infectious diseases because of the lack of health checkups and support for workers before and after business trips abroad. Among the respondents, 98.0% answered affirmatively that an ID was important for health management in the workplace, but 64.7% answered that it was difficult to manage an ID. The perceived capacity items to respond to IDs ranged from 3.0 points to 3.3 points. This scores were generally high. Conclusion: As the WRS is currently insufficient, it is necessary to develop an adequate WRS to IDs by addressing the identified problems.

• Journal of Korean society of Dental Hygiene
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• v.12 no.6
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• pp.1148-1157
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• 2012

Objectives : The purpose of this study is to analyze factors impacting dental treatment of fear and distrust of dentists. The subjects of this study consists of 720 middle & high school students in Daegu area. Methods : The data were collected from June 1, 2009 to September 30, 2009 by self-administrative questionnaires. The data received was analyzed using the descriptive statistic, t-test, ANOVA, and multiple linear regression analysis with level of significance as p<0.05 stimulus response factors in oral health education, often highly-experienced, and distrust of the dentists of factors the lower stimulus response factors are highly. Results : A female dental treatment of fear and distrust of dentists showed higher than male. Showed higher dental treatment of fear and the higher distrust of dentist. Showde the treatment-avoidance factors the higher patient of negligence factors and distrust of dentists factors are highly statistically significant. Showed the stimulus response factors in oral health education, often highly-experienced, and distrust of the dentists of factors the lower stimulus response factors are highly. Showed the similar results physiological arousal factors and the stimulus response factors. Conclusions : The results suggest that oral health status of improve adolescent before treatment of patients identify biological characteristics and personality can decrease dental treatment of fear and distrust of dentist.

• Journal of Korean Society for Quality Management
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• v.51 no.4
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• pp.607-618
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• 2023

Purpose: In this study, we proposed a plan to establish and implement a safety and health management system by utilizing corporate resources so that manufacturing companies can effectively respond to the Serious Accident Punishment Act. Methods: We identified critical factors and response strategies necessary for manufacturing companies to respond to the Severe Accident Punishment Act effectively and surveyed employees working at the company regarding their importance and performance. Results: In this study, we presented a method of strategically constructing the response strategies (20) shown in previous studies by matching them with the company's resources (leadership, organization, budget, education, and awareness). In particular, leadership refers to the ability of managers who can prevent serious accidents by carrying out safety and health security obligations to avoid safety and health hazards or risks to employees in the business or workplace that is controlled, operated, and managed. Conclusion: Based on the manager's firm leadership, the system's purpose and direction must be accurately set and sufficiently communicated to members. In addition, for companies to identify and improve risk factors on their own, a Process approach must be established to improve execution by referring to legal standards together with field managers and supervisors.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.15
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• pp.6627-6632
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• 2015

Background: We conducted a study exploring the clinical safety and efficacy of decitabine in patients with acute myeloid leukemia (AML) and myelodysplastic syndromes (MDS), combined with a complex karyotype. Materials and Methods: From April 2009 to September 2013, a total of 35 patients with AML/MDS combined with a complex karyotype diagnosed in the First Affiliated Hospital of Soochow University were included for retrospective analysis. All patients were treated with decitabine alone ($20mg/m^2$ daily for 5 days) or combination AAG chemotherapy (Acla 20mg qod*4d, Ara-C $10mg/m^2$ q12h*7d, G-CSF $300{\mu}g$ qd, the dose of G-CSF adjusted to the amount in blood routinely). Results: In 35 patients, 15 exhibited a complete response (CR), and 6 a partial response (PR), the overall response rate (CR+PR) being 60% (21 of 35). Median disease-free survival was 18 months and overall survival was 14 months. In the 15 MDS patients with a complex karyotype, the CR rate was 53.3% (8 of 15); in 20 AML patients with complex karyotype, the overall response rate was 65% (13 of 20). The response rate of decitabine alone (22 cases) was 56.5% (13 of 22), while in the combination chemotherapy group (13 cases), the effective rate was 61.5% (8 of 13)(P>0.05). There are 15 patients with chromosome 7 aberration, after treatment with decitabine, 7 CR, 3 PR, overall response rate was 66.7% (10 of 15). Of 18 patients with 3 to 5 kinds of chromosomal abnormalities, 66.7% demonstrated a response; of 17 with more than 5 chromosomal abnormalities, 52.9% had a response. In the total of 35 patients, with one course (23 patients) and ${\geq}$two courses (12 patients), the overall response rate was 40.9% and 92.3% (P<0.05). Grade III to IV hematological toxicity was observed in 27 cases (75%). Grade III to IV infections were clinically documented in 7 (20%). Grades I to II non-hematological toxicity were infections (18 patients), haematuria (2 patients), and bleeding (3 patients). With follow-up until September 2013, 7 patients were surviving, 18 had died and 10 were lost to follow-up. In the 6 cases who underwent allogeneic hematopoietic stem cell transplantation (HSCT) all were still relapse-free survivors. Conclusions: Decitabine alone or combination with AAG can improve outcome of AML/MDS with a complex karyotype, there being no significant difference decitabine in inducing remission rates in patients with different karyotype. Increasing the number of courses can improve efficiency. This approach with fewer treatment side effects in patients with a better tolerance should be employed in order to create an improved subsequent chance for HSCT.

• Journal of Korean Academy of Nursing
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• v.22 no.2
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• pp.238-247
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• 1992

Immigration of Koreans to the United States has increased since the 1960's. Adjusting to life in the United States produces a great deal of stress for immigrants. Despite better economic opportunites, many see the U.S. culture as threatening to their family and cultural values. Differences in culture, language, expectations and social behavior can lead to misunderstandings between health care providers and clients. These misunderstanding can leaf to frustration on the part of each. The ultimate result of this is that often Korean-immigrants do not get their health care needs met and stress response symptoms can lead to disease if there is no appropriate care. To determine the health care needs and concerns of Korean-Americans, a health needs assessment is needed. Appropriate and adequate information about the health care needs of these individuals is important as it relates to American policy changes allowing greater numbers of immigrants to enter the U.S. The purpose of this prospective study was to describe Korean-American stress response. This study focused on the primary presenting problems for which subjects reported having sought care. These included a variety of stress-related symptoms, including peripheral manifestations, cardiopulmonary symptoms, central-neurological symptoms, gastrointestinal symptoms, muscle tension, habitual patterns, depression, anxiety, emotional irritability and cognitive disorganization. Of the 300 subjects who entered the study, 80% (N＝223) completed the questionnaire in full. Demographically, the percentage of females and males was 50% each and they ranged in age from 20 to 69 years. Ninety percent of the subjects were highly educated, 25% owners of business, 25% white collar professionals, 15% employed in sales or as skilled /unskilled labor, 30% had no occupation : and 5% were housewives or students. The SOS inventory is designed to quantify self-perception of behavioral, cognitive, and physiological components of the stress response. It consisted of 94 items divided into 10 subscales. The result of this study are as follows : The total mean 505 of all subjects (N＝223 was .8129 ; the mean 505 for male(N＝114) was .7665 and for females, (N＝108) .8594. The level of symptoms for central-neurologic and muscle tension was higher for than for males. The highest stress response of all subjects was emotional irritability symptoms(1.0644) : the lowest stress response of all subjects was peripheral manifestation symptoms.

• Journal of Environmental Health Sciences
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• v.47 no.2
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• pp.166-174
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• 2021

Objectives: This study aimed to provide temporal Acute Exposure Guideline Levels (AEGL) for a hazardous substance as a pilot study. Methods: As one of the substances designated by the Korea Ministry of Environment as requiring preparations for potential accidents, formaldehyde was selected to estimate the AEGLs. The calculation was based on Haber's formula (Cn×t=k) using valid toxicity data (for humans/animals). A total of 96 points of AEGL levels were provided using an interval of five minutes over eight hours. Results: The AEGL-1 and 2 values were constant for the entire exposure duration at 0.9 ppm and 14 ppm, respectively. The values were obtained from clinical/animal tests, and the adaptation effect after a given exposure duration was also considered. AEGL-3 was based on animal toxicity data, and it was estimated from 127 ppm for the initial five minutes to 35 ppm for eight hours. Conclusions: More specific AEGL levels for formaldehyde could be obtained in this study using toxicity data with Haber's formula. Based on this methodology, it would be also possible to estimate AEGL levels that can be used at the scene of a chemical accident for other substances requiring preparation for potential accidents.