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http://dx.doi.org/10.5668/JEHS.2021.47.2.166

Estimation of Temporal Acute Exposure Guideline Levels for Emergency Response - A Brief Case using Formaldehyde -  

Kim, Eunchae (Department of Occupational Health, Daegu Catholic University)
Cho, Yong-Sung (Accident Prevention Assessment Division 2, National Institute of Chemical Safety, Ministry of Environment)
Lee, Chung-Soo (Accident Response Coordination Division, National Institute of Chemical Safety, Ministry of Environment)
Yang, Wonho (Department of Occupational Health, Daegu Catholic University)
Hwang, Seung-Ryul (Accident Response Coordination Division, National Institute of Chemical Safety, Ministry of Environment)
Park, Jihoon (Accident Response Coordination Division, National Institute of Chemical Safety, Ministry of Environment)
Publication Information
Journal of Environmental Health Sciences / v.47, no.2, 2021 , pp. 166-174 More about this Journal
Abstract
Objectives: This study aimed to provide temporal Acute Exposure Guideline Levels (AEGL) for a hazardous substance as a pilot study. Methods: As one of the substances designated by the Korea Ministry of Environment as requiring preparations for potential accidents, formaldehyde was selected to estimate the AEGLs. The calculation was based on Haber's formula (Cn×t=k) using valid toxicity data (for humans/animals). A total of 96 points of AEGL levels were provided using an interval of five minutes over eight hours. Results: The AEGL-1 and 2 values were constant for the entire exposure duration at 0.9 ppm and 14 ppm, respectively. The values were obtained from clinical/animal tests, and the adaptation effect after a given exposure duration was also considered. AEGL-3 was based on animal toxicity data, and it was estimated from 127 ppm for the initial five minutes to 35 ppm for eight hours. Conclusions: More specific AEGL levels for formaldehyde could be obtained in this study using toxicity data with Haber's formula. Based on this methodology, it would be also possible to estimate AEGL levels that can be used at the scene of a chemical accident for other substances requiring preparation for potential accidents.
Keywords
Chemical accident; Acute Exposure Guideline Level; emergency response; health effects;
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