• Journal of Korean Public Health Nursing
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• v.36 no.1
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• pp.107-123
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• 2022

Purpose: This study was done to develop and test a scale to measure the homeboundness for low-income aged who live in the community. Methods: This was nursing methodology research. Homeboundness Scale development process was composed of construct identification based on concept analysis using the Hybrid model, 35 initial items. This number was reduced to 31 items through face validity tests by 7 experts. The preliminary Homeboundness Scale for low-income aged was administered to 240 aged who registered and received visiting health care service in the community health center located in S city. Data were analyzed using item analysis, factor analysis, Pearson correlation coefficients, and Cronbach's alpha. Results: Twenty-two items were selected for the final scale. Three factors evolved from the factor analysis, which explained 66.0% of the total variance. The internal consistency, Cronbach's alpha, was .945 and reliability of the subscales ranged from .890 to .934. Conclusion: Homeboundness Scale demonstrated acceptable validity and reliability. It can be used to assess the Homeboundness of the low-income aged in practice and research.

• The Journal of Korean Society for School & Community Health Education
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• v.23 no.4
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• pp.49-61
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• 2022

Objectives: It is reported that the depression of women with disabilities is higher than that of men with disabilities and people with disabilities. Therefore, the purpose of this study is to identify the depression level and influencing factors of middle-aged women with disabilities. Method: For this study, the 2020 survey on the disabled was used. The subjects were 2,546 middle-aged and disabled women over the age of 40 who responded to the survey. For data analysis, SPSS Window 26.0 program was used. Descriptive analysis, chi-square test, and multiple logistic analysis were performed to identify factors affecting depression in middle-aged women with disabilities. Results: In this study, marital status, subjective economic status, disability type, subjective health status, subjective obesity, chronic disease, exercise, stress and suicidal ideation, and self-going ability variables of middle-aged and elderly women with disabilities were found to be related to depression. Factors affecting the depression of middle-aged women with disabilities were analyzed to be marital status, smoking, stress, and suicidal ideation variables. Conclusion: Stress and suicidal ideation should be reduced to effectively reduce depression and improve depression in middle-aged and elderly women with disabilities. And the development and application of health education and programs that can promote mental health are required.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.42 no.5
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• pp.434-441
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• 2009

This study was conducted to compare the biological activities of 7 melania snails from the family Pleuroceridae (Semisulcospira coreana, Koreanomelania nodifila, Semisulcospira forticosta, Koreoleptoxis globus ovalis, Semisulcospira libertina, Semisulcospira tegulata and Semisulcospira gottschei) in Korea. Among the 7 species, S. coreana, Korean. nodifila, S. forticosta and S. gottschei showed over 80% cytotoxicities on three cancer cell lines (SNU-1, A549 and Hep 3B) compared to the non-treatment, whereas S. libertina and S. tegulata showed almost no growth inhibition activities on the same cancer cell lines. In relation to ACE inhibition activity, only S. coreana, Korean. nodifila, and S. forticosta showed over 60% ACE inhibition activities, whereas other melania snails exhibited inhibition activities of lower than 25%. DPPH radical scavenging activities were also determined, and used to categories melania snails into three groups based on Duncan's multiple range test at P<0.05. The amount of TNF-${\alpha}$ produced by in vitro mouse peritoneal macrophage was determined according to bioactivity on L-929 cells. Three melania snails, S. coreana, Korean. nodifila and S. gottschei, exhibited 95.2%, 89.7% and 93.7% cell death(%) on L-929 cells, respectively. Glucose-6-phosphate dehydrogenase inhibitory activity was also obtained in the extract of S. coreana (31.9%) and Korean. nodifila (28.1%), showing that these extracts can be used as supplemental dietary health foods. In conclusion, we believe that the extracts of melania snails should be given due consideration in functional health food development.

• Asian Pacific Journal of Cancer Prevention
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• v.17 no.4
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• pp.1701-1704
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• 2016

Background: Stomach cancer (SC) is the second leading cause of cancer death with the rate of 10.4% in the world. The correlation between the incidence and mortality rates of SC and human development index (HDI) has not been globally determined. Therefore, this study aimed to determine the association between the incidence and mortality rates of SC and HDI in various regions. Materials and Methods: In this global ecological study, we used the data about the incidence and mortality rate of SC and HDI from the global cancer project and the United Nations Development Programme database, respectively. Results: In 2012, SCs were estimated to have affected a total of 951,594 individuals (crude rate: 13.5 per 100,000 individuals) with a male/female ratio of 1.97, and caused 723,073 deaths worldwide (crude rate: 10.2 per 100,000 individuals). There was a positive correlation between the HDI and both incidence (r=0.28, P<0.05) and mortality rates of SC (r=0.13, P = 0.1) in the world in 2012. Conclusions: The high incidence and mortality rates of SC in countries with high and very high HDI is remarkable which should be the top priority of interventions for global health policymakers. In addition, health programs should be provided to reduce the burden of this disease in the regions with high incidence and mortality rates of SC.

• Health Policy and Management
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• v.30 no.3
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• pp.270-276
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• 2020

Entering the fourth industrial revolution era, health technology is rapidly developing and the people's needs for medical services are gradually increasing. Establishing a life cycle management of health technology has emerged as a new policy agenda to cope with these changes. However, the management of health technology have been conducted without continuity and with several problems pointed out. Therefore, we suggest the reform agendas by stages to establish system for a life cycle management of health technology in the fourth industrial revolution era as follows. In the stage of development, it is important not only to provide research funding, but also consulting by professional about whole cycle of health technologies. In the phase of market entry, there are needs for enhance the system that would expand the early adoption for innovative technology and increase its effectiveness. After the spread of health technology to clinical settings, a reassessment and post management system should be established that have an institutional framework with strong price adjustment and exit mechanism. Furthermore, we hope that discussions will be brisk in macro perspective on the balancing of development in healthcare industry, health of people and national health insurance finance.

• Fashion & Textile Research Journal
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• v.14 no.1
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• pp.144-151
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• 2012

The patent application state of Europe, U.S.A, and Korea was analyzed to grasp the technology development trends and to suggest a direction for research development of health related shoes. Europe has high concentration of patent activity in corrective treatment, while Korea has high concentration in fitness and U.S.A in diet related fields. Numerous shape and structure designs were done to have the effect of corrective treatment. Adding weight to shoes has been used to create diet-effect, but it suggests a lack of technical methods to increase weight effectively. For fitness effect, variation of shape and structure of the outsole are often used.

• Proceedings of the Korean Society for Food Science of Animal Resources Conference
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• 2002.05a
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• pp.29-38
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• 2002

Today's food technologist is receiving increasingly pointed directions in the “selection of”and often “minimum amounts of”ingredients to use in the development of new food products. This increasing emphasis by marketing on “label”claims is real and gaining momentum in most market places. Thus, the development of functional foods that are providing customers with new and distinct nutritional choices. The driving force for the increased direction of the food technologist is that many governments are now allowing health related label claims on food products. These health claims are a result of very clearly and focused research that shows known nutritional benefits. The regulatory environment is well focused on the results of this peer reviewed research. In the USA, FDA has allowed several opportunities for health claims including fiber, soy protein and choline. This presentation will focus on only two of many functional ingredient options-the soy proteins and lecithin(choline).

• Archives of Pharmacal Research
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• v.22 no.4
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• pp.361-366
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• 1999

One of the potential causes of age-related neuronal damage can be reactive oxygen species (ROS), as the brain is particularly sensitive to oxidative damage. In the present study, we investigated the effects of aging and dietary restriction (DR) on ROS generation, lipid peroxidation, and antioxidant enzymes in cerebrum, hippocampus, and cerebellum of 6-, 12-, 18-, and 24-month-old rats. ROS generation significantly increased with age in cerebrum of ad libitum (AL) rats. However, no significant age-difference was observed in hippocampus and cerebellum. DR significantly decreased ROS generation in cerebrum and cerebellum at 24-months. On the other hand, the increased lipid peroxidation of AL rats during aging was significantly reduced by DR in all regions. Our results further showed that catalase activity decreased with age in cerebellum of AL rats, which was reversed by DR, although SOD activity had little change by aging and DR in all regions. In a similar way, glutathione (GSH) peroxidase activity increased with age in cerebrum of AL rats, while DR suppressed it at 24-months. These data further support the evidence that the vulnerability to oxidative stress in the brain is region-specific.

• Journal of mucopolysaccharidosis and rare diseases
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• v.2 no.1
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• pp.19-22
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• 2016

Purpose: Mucolipidosis type II (ML II), also known as I-cell disease is an autosomal recessive inherited disorder of lysosomal enzyme transport caused by a deficiency of the uridine diphosphate (UDP)-N-acetylglucosamine:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase (GlcNAc-phosphotransferase). Clinical manifestations are skeletal abnormalities, mental retardation, cardiac disease, and respiratory complications. A severely and rapidity progressive clinical course leads to death before 10 years of age. Methods/Results: In this study we diagnosed three cases of prenatal ML II in two different at-risk families. We compared two procedures -biochemical analysis and molecular analysis - for the prenatal diagnosis of ML II. Both methods require an invasive procedure to obtain specimens for the diagnosis. Biochemical analysis requires obtaining cell cultures from amniotic fluid for more than two weeks, and would result in a late diagnosis at 19 to 22 weeks of gestation. Molecular genetic testing by direct sequence analysis is usually possible when mutations are confirmed in the proband. Molecular analysis has an advantage in that it can be performed during the first-trimester. Conclusion: Molecular diagnosis is a preferable method when a prompt decision is necessary.

• The Korean Journal of Health Service Management
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• v.13 no.4
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• pp.33-44
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• 2019

Objectives: This study aimed to analyze the papers on nursing in the KJHSM (Korean Journal of Health Service Management) (2007-2018), to identify the research trends and to help the future development of nursing research. Methods: The data collection was carried out from September 1, 2019 to September 30, 2019. The 78 copies of the original text were provided by the KSHSM website, DBpia, and NDSL (National Digital Science Library) electronic database. Results: Forty-seven studies had a non-experimental design, with most having a descriptive research design (89.3%). The most common participants were nurses (55.7%) and nursing college students (26.1%). A questionnaire was the most commonly used research tools (96.2%) and data collection methods (95.0%). The major keywords were the terms included in the environmental domain among the meta-paradigms of nursing (43.6%). Conclusions: In order to expand the quantity and quality of nursing science in the KSHSM, efforts are needed to improve the quality of research participants, research tools, and sampling methods.