• Title/Summary/Keyword: Health research and development

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Hot melt extruded-based nano zinc as an alternative to the pharmacological dose of ZnO in weanling piglets

  • Oh, Seung Min;Kim, Min Ju;Hosseindoust, Abdolreza;Kim, Kwang Yeol;Choi, Yo Han;Ham, Hyung Bin;Hwang, Sung Jun;Lee, Jun Hyung;Cho, Hyun Jong;Kang, Wei Soo;Chae, Byung Jo
    • Asian-Australasian Journal of Animal Sciences
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    • v.33 no.6
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    • pp.992-1001
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    • 2020
  • Objective: This study was conducted to investigate the effects of hot-melt extruded ZnO nano-particles (HME-ZnO) as an alternative for P-ZnO on growth performance, nutrient digestibility, Zn bioavailability, intestinal microbiota, and intestinal morphology of weanling pigs. Methods: A total of 450 piglets (Landrace×Yorkshire×Duroc) were randomly allotted to five treatments based on initial body weight and sex. The experimental diets were fed in a meal form as phase 1 from d 0 to 14 and phase 2 from d 15 to 28. Treatments were the control diet without ZnO supplementation, the diet containing 2,500 ppm Zn as ZnO, and three diets containing 500, 1,000, or 2,500 ppm Zn as HME-ZnO. Results: The overall result showed a higher (p<0.01) average daily gain in weanling pigs fed ZnO-supplemented diets in comparison to the control diet. There was a decrease (p<0.01) in fecal score in the ZnO-supplemented diets. Dietary supplementation of ZnO improved (p<0.05) crude protein digestibility. The weanling pigs fed the P-ZnO diet had a lower (p<0.01) Zn digestibility in the feces than HME-ZnO supplemented treatments. Weanling pigs fed diets supplemented with ZnO had greater (p<0.05) Lactobacillus spp. populations and lower Clostridium spp. (p<0.05) and Coliforms (p<0.01) populations in the ileum. Weanling pigs fed diets supplemented with increasing concentrations of HME-ZnO linearly decreased Clostridium spp. (p<0.05) and Coliforms (p<0.01) in the ileum. Lower (p<0.05) Clostridium spp. and Coliforms counts in the colon were observed in pigs fed with ZnO-supplemented diets. Weanling pigs fed diets supplemented with ZnO showed a greater (p<0.01) villus height in the duodenum. Conclusion: Dietary supplementation of HME-ZnO and P-ZnO showed a potential to improve the digestibility of protein, intestinal Coliform and Clostridium, villus height in duodenum and ileum. Moreover, HME-ZnO showed a higher Zn digestibility compared with P-ZnO.

Quality Characteristics of the Germinated Brown Rice Wine Added with Red Pepper (고추를 첨가한 발아현미 술의 품질특성)

  • Park, Chan-Soon;Oh, Eun-Hee;Jeong, Heon-Sang;Yoon, Hyang-Sik
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.38 no.8
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    • pp.1090-1096
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    • 2009
  • This study is to develop wine with germinated brown rice and red pepper (Capsicum annuum) and to make effective use of the rice and red pepper. The results of alcohol fermentation were as follows. pH 5.5 was decreased to 4.5$\sim$5.1 during fermentation. The total acidity was changed from 0.56% in initial fermentation to 0.96$\sim$1.42% in after fermentation. Reducing sugar was changed from 0.27% in initial fermentation to 1.33$\sim$1.40% at the end of the fermentation. The ethanol content was 16.6$\sim$17.0% at the end of the fermentation. The addition of 10$\sim$50% red pepper did not have influence on the fermentation. From Hunter's L, a, and b values, a (redness) and b (yellowness) value were increased according to content of red pepper addition. The major volatiles were ethyl acetate, 1-propanol, 2-methyl-1-propanol, 3-methyl-butanol and benzeneethanol. Capsaicin content in the samples of red pepper addition was the highest in 50% and the lowest in 10%. In sensory evaluation, the wine with 20% red pepper had the highest acceptance scores in all of the properties examined than those of other samples.

Development of Detailed Korean Adult Eye Model for Lens Dose Calculation

  • Han, Haegin;Zhang, Xujia;Yeom, Yeon Soo;Choi, Chansoo;Nguyen, Thang Tat;Shin, Bangho;Ha, Sangseok;Moon, Sungho;Kim, Chan Hyeong
    • Journal of Radiation Protection and Research
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    • v.45 no.1
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    • pp.45-52
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    • 2020
  • Background: Recently, the International Commission on Radiological Protection (ICRP) lowered the dose limit for the eye lens from 150 mSv to 20 mSv, highlighting the importance of accurate lens dose estimation. The ICRP reference computational phantoms used for lens dose calculation are mostly based on the data of Caucasian population, and thus might be inappropriate for Korean population. Materials and Methods: In the present study, a detailed Korean eye model was constructed by determining nine ocular dimensions using the data of Korean subjects. The developed eye model was then incorporated into the adult male and female mesh-type reference Korean phantoms (MRKPs), which were then used to calculate lens doses for photons and electrons in idealized irradiation geometries. The calculated lens doses were finally compared with those calculated with the ICRP mesh-type reference computational phantoms (MRCPs) to observe the effect of ethnic difference on lens dose. Results and Discussion: The lens doses calculated with the MRKPs and the MRCPs were not much different for photons for the entire energy range considered in the present study. For electrons, the differences were generally small, but exceptionally large differences were found at a specific energy range (0.5-1 MeV), the maximum differences being about 10 times at 0.6 MeV in the anteroposterior geometry; the differences are mainly due to the difference in the depth of the lens between the MRCPs and the MRKPs. Conclusion: The MRCPs are generally considered acceptable for lens dose calculations for Korean population, except for the electrons at the energy range of 0.5-1 MeV for which it is suggested to use the MRKPs incorporating the Korean eye model developed in the present study.

Transmission electron microscopical study of the developing colonic epithelia in fetuses and neonates in Korean native goat (Carpus hircus) (한국재래산양 태아 및 신생아의 결장상피 발달에 관한 투과전자현미경적 연구)

  • Kim, Chong-Sup;Jung, Soon-Hee;Won, Chung-Kil;Lee, Jong-Hwan;Cho, Gyu-Hyen;Kwak, Soo-Dong;Cho, Kyu-Woan;Kim, Moo-Kang;Song, Chi-Won
    • Korean Journal of Veterinary Research
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    • v.42 no.2
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    • pp.147-152
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    • 2002
  • The morphological development of colonic epithelia in fetuses between 60-. 90-, and 120-days gestation and neonates of Korean native goat were investigated by transmission electron microscopy. In the 60-day-old fetuses, the colonic epithelial cells contained nuclei, nucleoli, mitochondria, free ribosomes, and shoo granular and agranular endoplasmic reticula. The zonula occludens, zonula adherens, desmosomes, short microvilli, and masses of glycogen granules were also obsrved. The goblet cells contained a few secretory granules. In the 90-day-old fetuses, the cell organelles of the colonic epithelial cells were better developed than those in the 60 day old fetuses. Increased number of endoplasmic reticula, digitiform intercellular junctions, mitochondria, and Golgi complexes was observed. The goblet cells contained a lot of secretory granules. In the 120-day-old fetuses, the colonic epithelial cells contained long microvilli and well developed cell organelles. The nuclear cleft and large intercellular space were also appeared. Nunerous fibroblasts were seen in the basement membrane. The number of goblet cells was further observed. In the 120 day old fetuses, all colonic epithelial cells shape simple columnar cells. In newborns, the colonic epithelial cells were covered with extensive microvilli. There were many goblet cells with a lot of secretory granules protruding into the intestinal lumen, and some goblet cells secreted their secretory granules into the lumen. In the 60-and 90-day-old fetuses, the colonic epithelial cells appeared to be either simple columnar or stratified columnar depending on areas.

Biofilm Processes for Volume Decrease in Recirculating Water Treatment Systems for Aquaculture

  • Kim Jeong-Sook;Yoon Gil-Ha;Ghim See-Jun;Kang Lim-Seok;Lee Byung-Hun
    • Fisheries and Aquatic Sciences
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    • v.1 no.2
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    • pp.242-249
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    • 1998
  • The engineering aspect of water treatment processes in the recirculating aquaculture system was studied. To recycle the water in the aquaculture system, a wastewater treatment process was required to maintain high water quality for the growth and health of the cultured fish. In this study, three different biofilm processes were used to reduce the concentration of organic matters and ammonia from the recirculating water - two phase fluidized bed, three phase fluidized bed, and trickling filter. The objectives of this research were to evaluate the optimum treatment conditions of the biofilm processes for the recirculating aquaculture system, and thereby reduce the volume of biofilm processes, which are commonly used for the recycle water treatment processes for aquaculture. The result of this study showed that the removal efficiency of organic matters by trickling filter was found to be lower than that of the fluidized bed. In the trickling filter system, anthracite showed better organic removal efficiency than crushed stone as a media. In the two phase fluidized bed, the maximum removal efficiency of either organics or ammonia was obtained when both the packing rate of media was maintained to $40\%$ of total reactor depth excepting sediment zone and the bed expansion rate was maintained to $100\%$. When 100 tilapia (Oreochromis niloticus) of each average 200g was reared, the pollutant production rate was 0.07g $NH_4\;^+-N/kg$ fish/day and 0.06g P04-3-P/kg fish/day, and sludge production rate was 0.39 g SS/kg fish/day. In the two phase and three phase fluidized bed, the volume of water treatment tank could be calculated from an empirical equation by using the relationship between the influent COD to $NH_4\;^+-N$ ratio (C/N, -), media concentration (Cm, g/L), influent ammonia nitrogen concentration (Ni, mg/L), effluent ammonia nitrogen concentration (Ne, mg/L), bed expansion rate $(E,\;\%)$, and influent flowrate $(Q,\;m^3/hr)$. The empirical equation from this study is $$V_2\;=\;10^{3.1279}\;C/N^{3.5461}\;C_m\;^{-3.7473}\;N_i\;^{4.6477}\;E^{0.0326}\;N_e\;^{-0..8849}\;Q\;(Two\;Phase\;FB) V_3\;=\;10^{11.7507}\;C/N^{-1.2330}\;C_m\;^{-6.5715}\;N_i\;^{1.5091}\;N_e\;^{-1.8489}\;Q (Three\;Phase\;FB)$$

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A Study on Self efficacy Difference between User and Nonuser of Smartphone (자기 효능감에 의한 스마트폰 사용의도 연구)

  • Lee, JangHyung;Kim, Jong-Won;Sung, Baek-Chun;Choi, Young-Jin
    • Journal of the Korea Society of Computer and Information
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    • v.18 no.2
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    • pp.157-164
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    • 2013
  • Self efficacy is a term used in psychology, roughly corresponding to a person's belief in their own competence. It has been defined as the belief that one is capable of performing in a certain manner to attain certain goals. It is believed that our personalized ideas of self-efficacy affect our social interactions in almost every way. Understanding how to foster the development of self-efficacy is a vitally important goal for positive psychology because it can lead to living a more productive and happy life. The objective of this study is to show difference of the relationship between user and non-user in smartphone by self efficacy. For this purpose, we propose a research model which consists of 3type' self efficacy. For empirical test of this model, the sample data is collected from employee in a company and divided into two groups by user and nonuser. By multi-group analysis, we show two groups are different from each other in the relationship between user and nonuser of smartphone. Results show difference of the relationship smartphone user and non-user's self-efficacy(self-control self-efficiacy and problem difficulty preference).

A Study on the IT Outsourcing for Service Level Agreement in Public Agencies (공공기관에서의 서비스 수준 협약(SLA)에 따른 IT 아웃소싱에 관한 연구)

  • Lee, Sung Ho;Kim, Hee Wan;Kim, Dong Soo
    • Journal of Service Research and Studies
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    • v.2 no.1
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    • pp.47-59
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    • 2012
  • With the rapid development of the Internet, public agencies and private companies introduced 'IT outsourcing in order to maintain and repair the information systems. Also they have utilized the SLA in order to manage it. Although IT outsourcing as a way to promote effective SLA are being introduced, the introduction of service level agreements or those introduced universal effectiveness did not demonstrate in the public agencies. The importance of outsourcing in the information systems is growing, but the increase in size of the business information, IT technology diversification, expansion of information between systems interconnection, information system operating and maintenance costs with the increase of information systems to streamline operations, increase the need for versatility is growing gradually. In this paper we investigates IT outsourcing in public agencies as a way to promote effective service level agreement(SLA) with the introduction and consideration, and through the application of SLA mutual customers and IT service organizations make a clear point of management and IT service levels and IT services for improved mind and strengthen the effectiveness of preventive activities can be seen.

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Investigation of the Super-resolution Algorithm for the Prediction of Periodontal Disease in Dental X-ray Radiography (치주질환 예측을 위한 치과 X-선 영상에서의 초해상화 알고리즘 적용 가능성 연구)

  • Kim, Han-Na
    • Journal of the Korean Society of Radiology
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    • v.15 no.2
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    • pp.153-158
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    • 2021
  • X-ray image analysis is a very important field to improve the early diagnosis rate and prediction accuracy of periodontal disease. Research on the development and application of artificial intelligence-based algorithms to improve the quality of such dental X-ray images is being widely conducted worldwide. Thus, the aim of this study was to design a super-resolution algorithm for predicting periodontal disease and to evaluate its applicability in dental X-ray images. The super-resolution algorithm was constructed based on the convolution layer and ReLU, and an image obtained by up-sampling a low-resolution image by 2 times was used as an input data. Also, 1,500 dental X-ray data used for deep learning training were used. Quantitative evaluation of images used root mean square error and structural similarity, which are factors that can measure similarity through comparison of two images. In addition, the recently developed no-reference based natural image quality evaluator and blind/referenceless image spatial quality evaluator were additionally analyzed. According to the results, we confirmed that the average similarity and no-reference-based evaluation values were improved by 1.86 and 2.14 times, respectively, compared to the existing bicubic-based upsampling method when the proposed method was used. In conclusion, the super-resolution algorithm for predicting periodontal disease proved useful in dental X-ray images, and it is expected to be highly applicable in various fields in the future.

The Effect of Children's Beverages on Degradation of Dental Resin-Based Pit and Fissure Sealant (어린이 음료가 레진계 치면열구전색제의 화학적 분해에 미치는 영향)

  • Min, Hee-Hong;Kim, Hyun-Jin;Lee, Hye-Jin
    • Journal of dental hygiene science
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    • v.18 no.6
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    • pp.367-373
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    • 2018
  • The consumption of beverages among children is rising. The purpose of this study was to examine the effect of kid's drink on dental resin-based pit and fissure sealant. Pororo, I-kicker, Sunkist kids were included in the experimental groups, and Samdasu was included in the control group. A conventional dental sealant material ($Clinpro^{TM}Sealant^{(R)}$) was selected for this study. Resin specimens (8 mm in diameter and 1 mm in thickness) were prepared according to manufacturers' instructions and the initial roughness (Ra) was then measured. The pH of all the four groups was measured using a pH meter. The specimens were individually immersed in 5 ml of the experimental solutions and stored at $37^{\circ}C$ for 72 hours. Following this, the surface roughness of the resin specimens was measured by Surftest. The concentration of residual monomer released was determined by high performance liquid chromatography (HPLC). The surface morphology of the resin specimen was evaluated before and after storage by scanning electron microscopy (SEM). Data were statistically analyzed using Kruskal-Wallis and Duncan's test. The results showed that all the children's beverages examined in this study contained citric acid. The pH of I-kicker was the lowest ($3.03{\pm}0.01$), followed by that of Sunkist kids ($3.26{\pm}0.02$) and Pororo ($3.47{\pm}0.02$). We observed an increase in the surface roughness of resin specimens after 72 h of immersion in all the beverages tested (p<0.05). There was matrix degradation after immersion, visualized on SEM image, in all the beverage groups. Bisphenol-A-glycidyl methacrylate was not detected after 72 hours, but triethylene glycol dimethacrylate levels were increased in all the beverages tested during the 72 hours by HPLC. These results suggest that intake of beverages containing acid can cause degradation of the resin-based pit and fissure sealants in children.

The Effects of College Student Humanity Leadership Program on Personality, Self-Esteem, Leadership and Life Satisfaction (대학생 인성리더십 프로그램이 인성과 자아존중감 및 리더십과 삶의 만족도에 미치는 효과)

  • Choi, Mi-Sug
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.20 no.8
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    • pp.441-448
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    • 2019
  • The purpose of this study is to verify whether the university-based humanity leadership program is effective in improving personality, self-esteem, leadership and life satisfaction. The subjects of this study were 45 students in the experimental group and 45 students in the control group, and the control group did not participate in the leadership program. The research was conducted from September 5, 2017 to November 28, 2017. The program was conducted twice a month for a total of six sessions. To verify the effectiveness of the program, preliminary tests were conducted before the first session and then post-tests were conducted after the program. The test consisted of a questionnaire survey on personality, self-esteem, leadership, and life satisfaction. Data analysis was performed by using SPSS 24.0 for the frequency analysis and the response sample t test for determining the differences in the post-test scores of the experimental group. First, there was a significant difference in personality, self-esteem and life satisfaction. Second, positive effects were found in three domains that included honesty, self-esteem, relationships with others, leadership, popularity, and self-assertiveness. This result suggests that it is necessary to improve the satisfaction of life through the formation of relationships with other people, and with an emphasis on honesty, in the program's development and contents.