• Journal of Medicine and Life Science
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• v.19 no.1
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• pp.1-7
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• 2022

Learning disabilities (LD), also known as learning disorders, refers to cases in which an individual experiences lower academic ability as compared to the normal range of intelligence, visual or hearing impairment, or an inability to peform learning. Children and adolescents with learning disabilities often have emotional or behavioral problems or co-existing conditions, including depression, anxiety disorders, difficulties with peer relationships, family conflicts, and low self-esteem. In most cases, attention deficit and hyperactivity disorder coexists. As learning disabilities have the characteristics of a difficult heterogeneous disease group that cannot be attributed to a single root cause, they are diagnosed based on an interdisciplinary approach through medicine and education, such as mental health medicine, education, psychology, special education, and neurology. In addition, for the accurate diagnosis and treatment of learning disabilities, the diagnosis, prescription, treatment, and educational intervention should be conducted in cooperation with doctors, teachers, and psychologists. The treatment of learning disabilities requires a multimodal approach, including medical and educational intervention. It is suggested that educational interventions such as the Individualized Education Plan (IEP) and the Response to Invention (RTI) should be implemented.

• Journal of Korea Society of Industrial Information Systems
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• v.14 no.4
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• pp.65-74
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• 2009

The risk of health impairment due to poor ventilation, fire and explosion by inflammable materials, and other unintended occurrences is always present in dangerous workplaces such as manholes, underground septic tanks, storage tanks and confined areas. Therefore, it a system which can monitor harmful working environment through sensors in workplace on a realtime basis and keep workers safe from the risk is needed. This paper has attempted to design an inference engine to monitor harmful environments in the workplace. The proposed inference engine has a rule-based system structure using JESS. This system is not confined to a particular computing platform and is easily interlocked with OSGi-based middleware.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.17 no.9
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• pp.2377-2398
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• 2023

In our daily lives, we engage in a variety of tasks that rely on our senses, such as seeing. Blindness is the absence of the sense of vision. According to the World Health Organization, 2.2 billion people worldwide suffer from various forms of vision impairment. Unfortunately, blind people face a variety of indoor and outdoor challenges on a daily basis, limiting their mobility and preventing them from engaging in other activities. Blind people are very vulnerable to a variety of hazards, including falls. Various barriers, such as stairs, can cause a fall. The Internet of Things (IoT) is used to track falls and send a warning message to the blind caretakers. One of the gaps in the previous works is that they were unable to differentiate between falls true and false. Treating false falls as true falls results in many false alarms being sent to the blind caretakers and thus, they may reject the IoT system. As a means of bridging this chasm, this paper proposes an intelligent shoe that is able to precisely distinguish between false and true falls based on three sensors, namely, the load scale sensor, the light sensor, and the Flex sensor. The proposed IoT system is tested in an indoor environment for various scenarios of falls using four models of machine learning. The results from our system showed an accuracy of 0.96%. Compared to the state-of-the-art, our system is simpler and more accurate since it avoids sending false alarms to the blind caretakers.

• Journal of Microbiology and Biotechnology
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• v.34 no.6
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• pp.1328-1339
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• 2024

Cadmium (Cd) is a prevalent environmental contaminant that poses a potential hazard to the health of both humans and animals. In this study, biosynthesized selenium-enriched Lactobacillus plantarum and selenium nanoparticles (SeNPs) were developed and evaluated for their protective effects against Cd-induced hepatic injury in mice through oral administration for 4 weeks. Cadmium exposure resulted in severe impairment of liver function, as evidenced by increased levels of serum markers of liver injury and, oxidative stress and significant damage to liver tissue, and a notable decrease in the diversity of the intestinal microbiota. Oral administration of Se-enriched L. plantarum (LS) reduced cadmium accumulation in the liver by 49.5% and, restored other cadmium-induced damage markers to normal levels. A comparison of the effects with those of L. plantarum (L) and SeNPs isolated from LS revealed that LS could more effectively alleviate hepatic oxidative stress and reduce the intrahepatic inflammatory responses of the liver, further protecting against cadmium-induced liver injury. These findings suggest that the development of LS may be effective at protecting the liver and intestinal tract from cadmium-induced damage.

• Women's Health Nursing
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• v.18 no.1
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• pp.1-16
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• 2012

Purpose: The purpose of this study was to describe the experiences of the process of the change in cognitive function for women treated with chemotherapy for breast cancer. Methods: There were ten participants in total in this study. Data were gathered utilizing in-depth interviews over 3 times from September 2010 to January 2011. Data were analyzed by employing Strauss and Corbin's (1998) grounded theory methodology. Results: Findings indicate that causal conditions of these results were 'side effects of chemotherapy' and 'menopausal state', including contextual conditions as, 'mental fatigue' and 'anxiety about recurrence'. The core category was identified as 'confronting with unexpected chaos'. Intervening conditions were 'support from other people', 'lack of information on cognitive impairment'. Interaction strategies were 'changing the habit of life', 'making efforts for living life' and 'seeking for medical information'. Consequences of the process were 'physical restriction', 'difficulty in social life', 'disturbed working ability' and 'psychological distress'. Conclusion: The results of this study show that nurses should recognize there is a notable difference between individual patient's contextual conditions and interactive strategies. Furthermore educational information and individualized intervention should be provided to improve cognitive function for women with breast cancer.

• The Journal of Korea Assosiation for Disability and Oral Health
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• v.10 no.1
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• pp.43-46
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• 2014

Cerebral Palsy is a genetic term referring to abnormalities of motor control caused by damage to a child's brain early in the course of development. Due to the impairment of balanced perioral muscle development, the prevalence of malocclusions in patients with cerebral palsy such as maxillary protrusion is high. But most clinicians may feel uncomfortable to treatment of these problems. Here a case report about mitigation of maxillary anterior teeth protruded in patient with cerebral palsy. 8y 4m old boy who have cerebral palsy visited our dental hospital. He showed severely protrusive maxillary anterior teeth with mouth breathing and could not close his mouth. He and his mother wanted to improve dental and facial esthetic problem. Specially designed or modified intraoral fixed appliance and rubber elastic chain was used in the therapy. Treatment carried out for 8 months and we could observe maxillary incisor angle was improved and mouth breathing habit was stopped. In conclusion, modified fixed appliance therapy for the patients with cerebral palsy might be useful. Continuous rehabilitation training of lips should be followed after treatment to correct imbalance of muscle tone.

• The Journal of Korea Assosiation for Disability and Oral Health
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• v.10 no.2
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• pp.93-96
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• 2014

Brain disorder disability is assessed when organic brain lesion such as cerebral palsy, traumatic brain injury, or stroke causes physical impairment which limits daily activites substantially according to its level and range of paralysis or the presence of involuntary movement. According to the disabled person welfare law in Korea, grade I brain disorder is assessed when one is in continuous irreversible state of coma without the ability to prolong one's life without other's help. Self-injurious behavior is defined as the non-suicidal intentional or unintentional injury to one's own body which can occur repetitively temporarily or chronically. People with decreased consciousness often exhibit increased self-injurious behavior which is most commonly associated with tongue or lip biting. This report documents a successful self -injurious lip biting treatment of a brain lesion patient within a short time by applying a removable acrylic resin appliance including posterior bite block.

• Journal of Pharmacopuncture
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• v.22 no.4
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• pp.231-238
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• 2019

Objectives: Alzheimer's disease (AD), an overwhelming neurodegenerative disease, has deleterious effects on the brain that consequently causes memory loss and language impairment. This study was intended to investigate the neuroprotective activity of the two essential oils (EOs) from Iranian Pistacia khinjuk (PK) leaves and Allium sativum (AS) cloves against β-Amyloid 25-35 (Aβ25-35) induced elevation of cholinesterase enzymes in AD. Methods: The EOs of PK (PKEO) and AS (ASEO) were prepared and analyzed in terms of extraction yield, phenolic content, and cholinergic markers in vitro. Moreover, both were administered orally to adult male Wistar rats at concentrations of 1, 2, and 3%. The inhibitory potential of PKEO and ASEO was compared with Donepezil (0.75 mg/kg) against the high activities of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes. Results: PKEO reached an inhibition rate of 83.6% and 81.4% against AChE and BChE, respectively. ASEO had lower anti-cholinesterase activity (65.4% and 31.5% for the inhibition AChE and BChE). PKEO was found to have more phenolic content than ASEO. A significantly positive correlation was observed between the total phenolics and anti-cholinesterase potential. In rats, both EOs decreased the enzyme activity in a concentration-dependent manner. As compared with Donepezil, the significant difference in the AChE and BChE inhibition occurred as rats were treated with PKEO 3% (p < 0.05). Conclusion: It could be concluded that PKEO and ASEO are potent inhibitors of AChE and BChE in rats that hold promise to be used for the treatment of AD.

• Korean Journal of Biological Psychiatry
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• v.6 no.1
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• pp.12-20
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• 1999

In order to understand the pathogenesis and progression of some synaptic loss related neuropsychiatric diseases, We attempted to develop a computer model in this study. We made a simple autoassociative memory network remembering numbers, transformed it into a disease model by pruning synapses, and measured its memory performance as a function of synaptic deletion. Decline in performance was measured as amount of synaptic loss increases and its mode of decline is sudden or gradual according to the mode of synaptic pruning. The developed computer model demonstrated how synaptic loss could cause memory impairment through a series of computer simulations, and suggested a new way of research in neuropsychiatry.

• Proceedings of the KAIS Fall Conference
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• 2009.12a
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• pp.501-504
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• 2009

Sympathetic skin response (SSR) is defined as a minute change of skin potential after electrical stimulation. This test measures the change in voltage that originates from the surface of the skin and is attributed to sudomotor activity. The aim of this study was to define the criteria for validation of the responses. 40 normal subjects (20-73 years of age) with non-sympathetic dysfunction were tested and SSR was generated form all subjects. SSR latency was 1331.22${\pm}$177.51ms in the right palm, 1331.74${\pm}$156.42ms in the left palm, 1851.79${\pm}$220.99ms in the right sole, and 1874.10${\pm}$215.01ms in the left sole. And SSR amplitude was 595.83${\pm}$221.16${\mu}$V in the right palm, 605.33${\pm}$226.45${\mu}$V in the left palm, 291.76${\pm}$133.36${\mu}$V in the right sole, and 288.77${\pm}$129.70${\mu}$ V in the left sole. SSR latency and amplitude had no significantly difference between the right and the left side. SSR latency was consistently shorter (p<0.001) and SSR amplitude higher (p<0.001) in feet than in hands. SSR waveforms were P-type (32 subjects, 75%) and N-type (8 subjects, 25%), respectively. The SSR latency and amplitude in palms/soles were closely correlated with age (p<0.05) and height (p<0.05). The SSR test is one of methods assessing impairment of sympathetic fibers in peripheral neuropathy as well as a disorder of sympathetic system in other diseases and so our results from normal healthy subjects can be used as clinical criteria for SSR test.