• Journal of East-West Nursing Research
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• v.16 no.2
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• pp.122-130
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• 2010

Purpose: This study was aimed at finding factors influencing cognitive impairment which is one of the typical symptoms among the demented elderly. Methods: The number of subjects was 417 elderly residents aged over 65 yr in a community. A cognitive function and a depression level were measured using the Korean Version of Mini-Mental State Examination (MMSE-K) and the Korean Form of Geriatric Depression Scale (KGDS). Alcohol abuse was measured using the CAGE instrument. Chi-square test and Logistic regression analysis were conducted to identify factors affecting cognitive impairment. Results: The prevalence rates of cognitive impairment of the sample was 43.5%. Sex, age, educational level, perceived health and alcohol abuse were strong factors influencing cognitive impairment. However, the effects of smoking, living alone, depression, family history in dementia and stroke were not strong. Conclusion: Risk for cognitive impairment were increased by being female and older than 70 yr, having low education, perceiving health as poor, and drinking alcohol abusively. Therefore, a reinforcement system, continuous research and the development of proper programs should be preformed in order to prevent cognitive impairment.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.2
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• pp.247-260
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• 2018

This study examined the mental health status (depression, cognitive impairment and dementia) and its association with the related factors in the elderly people who were admitted from long-term care insurance. The study subjects were 1,488 people (male 740, female 748) aged over 70 years of age who had been recognized for long-term care insurance services in the years 2011~2014 from the National Health Insurance Corporation. The data collected from the National Health Insurance Corporation set forth a lifestyle questionnaire, itemized health screening tests, and long-term care as recognition data for research purposes. As a result, depression, cognitive impairment, and dementia of subjects increased significantly with age. As a multiple logistic regression result, the risk ratios of depression, cognitive impairment, and dementia, which indicated the mental health status, were significantly higher in women than in men, in the lower body weight group than in the overweight group, in the smoking group than in the non-smoking group, and in the drinking group than in the non-drinking group. These results suggest that the mental health status (depression, cognitive impairment, and dementia) of subjects decreased with increasing age, particularly the group with poor health related behaviors, such as smoking, drinking, and regular exercise, indicating that the mental health condition is lower than in the good group.

• Research in Community and Public Health Nursing
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• v.12 no.2
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• pp.417-427
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• 2001

Purpose: The aim of this study is to identify the influence of visual and hearing impairment on the activities of daily living of community dwelling elderly. Methods: Data were collected by home visiting interviewers from 452 older people aged 65 years or older living in community. Resident Assessment Instrument MDS-HC(2.0version) was used for data collection. Data analysis for descriptive statistics, Chi-square test and multiple regression was made by SAS 6.2 Results: 34.7% of the subject had hearing impairment and 64.3% had visual impairment Among IADL. one half of them were dependent in ordinary house work and meal preparation. In the case of ADL. 13.9% of subjects were dependent in bathing and 8.9% in personal hygiene. There was significant difference in IADL performance by visual and hearing impairment On the other hand, ADL performance showed the significant difference. only in the case of hearing impairment. As the result of input of visual and hearing impairment in the process of regression. variances were increased from 3% to 11%. Conclusions: Large proportions of older people living in the community have visual and hearing impairment. It could be confirmed that hearing and vision were significant factors influencing on IADL performance of older people. Intervention and support policy for elderly needs to focus on improvement of visual and hearing impairment.

• Korean Journal of Social Welfare
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• v.46
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• pp.319-348
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• 2001

The primary purpose of this study is to examine the buffering effect of social welfare services on the relationship between the level of older persons' impairment and burden experienced by the family caregivers. It also assessed the level of caregiving burden as well as the effect of both older person's impairment and the characteristics of the caregivers on burden. The survey data collected from 150 community residing family caregivers was used for analyses. Findings are as follows. First, the caregivers are more burdened in the deterioration of mental health, scarce time for oneself, and the suffering of social life than in other areas of burden. Second, the more severe the physical and the mental impairment of the elder, the more burden the caregivers experience. The caregivers' characteristics such as the worse mental health, the lower level of attachment to the elder, the longer caregiving hours are also related to the higher level of caregiving burden. Third, the caregivers' use of adult day care and respite care services buffer the relationship between the level of impairment of older persons and the caregiving burden. However, social work counselling, visiting nurse, homemaker services do not have such buffering effects. Among informal support, instrumental support buffers the relationship between the elder's physical impairment and burden, while emotional support buffers the relationship between the elder's mental impairment and burden. According to the results, implication for social welfare services and practice methods for the family caregivers was discussed.

• Korean Journal of Occupational Health Nursing
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• v.17 no.1
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• pp.55-63
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• 2008

Purpose: The purpose of this paper is to analyze the effect of job stress on work impairment. Method: 354 workers' data from Seoul and the Gyeonggi area were collected between February 1 and March 30 2006 by structured questionnaire. The questionnaire was meant to determine demographic data, job stress, and work impairment questionnaire. Data analyzed by SPSS 12.0 and AMOS 5.0 program. Results: Job stress was ranked job demand, insufficient job control, organizational system, lack of reward, job insecurity, interpersonal conflict, and occupational climate. The work impairment of completing work was increased when the stress of insufficient job control, lack of reward, job insecurity, and occupational climate were increasing. The work impairment of avoiding distraction was increased when the stress of job demand, insufficient job control, organizational system, lack of reward, job insecurity, and occupational climate were increasing. The stress of job demand, lack of reward, job insecurity, and occupational climate had an effect on avoiding distraction. The stress of lack of reward and occupational climate had an effect on completing work. Conclusion: If employers manage job stress of job demand, lack of reward, job insecurity, and occupational climate, their business will benefit.

• Nutrition Research and Practice
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• v.16 no.2
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• pp.147-160
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• 2022

BACKGROUND/OBJECTIVES: Patients with chronic kidney disease (CKD) have a high concentration of uremic toxins in their blood and often experience muscle atrophy. Indoxyl sulfate (IS) is a uremic toxin produced by tryptophan metabolism. Although an elevated IS level may induce muscle dysfunction, the effect of IS on physiological concentration has not been elucidated. Additionally, the effects of ursolic acid (UA) on muscle hypertrophy have been reported in healthy models; however, it is unclear whether UA ameliorates muscle dysfunction associated with chronic diseases, such as CKD. Thus, this study aimed to investigate whether UA can improve the IS-induced impairment of mitochondrial biogenesis. MATERIALS/METHODS: C2C12 cells were incubated with or without IS (0.1 mM) and UA (1 or 2 μM) to elucidate the physiological effect of UA on CKD-related mitochondrial dysfunction and its related mechanisms using real-time reverse transcription-polymerase chain reaction, western blotting and enzyme-linked immunosorbent assay. RESULTS: IS suppressed the expression of differentiation marker genes without decreasing cell viability. IS decreased the mitochondrial DNA copy number and ATP levels by downregulating the genes pertaining to mitochondrial biogenesis (Ppargc1a, Nrf1, Tfam, Sirt1, and Mef2c), fusion (Mfn1 and Mfn2), oxidative phosphorylation (Cycs and Atp5b), and fatty acid oxidation (Pdk4, Acadm, Cpt1b, and Cd36). Furthermore, IS increased the intracellular mRNA and secretory protein levels of interleukin (IL)-6. Finally, UA ameliorated the IS-induced impairment in C2C12 cells. CONCLUSIONS: Our results indicated that UA improves the IS-induced impairment of mitochondrial biogenesis by affecting differentiation, ATP levels, and IL-6 secretion in C2C12 cells. Therefore, UA could be a novel therapeutic agent for CKD-induced muscle dysfunction.

• Journal of Korean society of Dental Hygiene
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• v.24 no.3
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• pp.243-251
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• 2024

Objectives: This study used secondary data from the 2021 Community Health Survey to identify the impact of dysphagia on mental health-related characteristics among older adults, selecting 73,970 individuals aged 65 years and older. Methods: Frequency analysis, χ²-test, and multiple logistic regression were conducted to identify risk factors affecting mental health-related characteristics among older adults. Results: Dysphagia was most common among individuals with the following demographic characteristics: female, aged 85 years and older, three-generation household and household income in the 1st quintile. Chewing discomfort according to mental health-related characteristics was higher in older adults with cognitive impairment and depression. Sex, age, education level, household income, and chewing discomfort were significant for cognitive impairment, whereas sex, age, household type, education level, household income, and chewing discomfort were significant for depression. Conclusions: The above results confirmed that chewing discomfort contributes to mental health issues such as cognitive impairment and depression. It is therefore necessary to recognize chewing discomfort as an important health problem affecting the mental health of older adults, and to develop a multifaceted dental hygiene approach to target community-dwelling older adults who suffer from chewing discomfort.

• Therapeutic Science for Rehabilitation
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• v.12 no.3
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• pp.61-77
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• 2023

Objective : This study analyzed the correlation between cognitive function and oral health-related quality of life (OHQoL). Methods : Demographic and clinical characteristics were extracted and utilized for subjects aged 45 years or older who participated in the 8th Korean Longitudinal Study on Aging in 2020. The dependent variable was the Geriatric Oral Health Assessment Index, and the independent variable was the level of cognitive function classified by the Mini-Mental State Examination scores. The analysis method used inverse probability of treatment weighting (IPTW). Then, the association between cognitive function and OHQoL was analyzed by multiple regression analysis. Results : Among the participants, 4,367 (71.40%) had normal cognition, 1,155 (18.89%) had moderate cognitive impairment, and 594 (9.71%) had severe cognitive impairment. As a result of analysis by applying IPTW, there was a negative correlation between the cognitive function group and OHQoL (normal vs. moderate: β = -2.534, p < .0001; normal vs. severe: β = -2.452, p < .0001). Conclusion : After propensity score matching, mild cognitive impairment showed a more negative association than severe cognitive impairment. Therefore, patients with cognitive impairment require oral health management education to improve OHQoL regardless of the level of cognitive impairment.

• Korean Journal of Adult Nursing
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• v.24 no.2
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• pp.171-182
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• 2012

Purpose: This study aimed to identify depression and its predictors among Korean community-dwelling elderly with mild cognitive impairment. Methods: Secondary data analyses of the data collected by the "Study on tailored integration program for reinforcing cognitive and physical function of the frail elderly. The study used data from one-to-one interviews using structured questionnaires. The subjects were 346 community-dwelling elderly who visited a healthcare center in Seoul, Korea. A descriptive correlational study design was utilized to explore depression and its predictors including physical factors and psychosocial factors among the elderly with mild cognitive impairment. Data were analyzed using t-test, Pearson's correlation, and hierarchical regression. Results: Mean score of depression was within normal limit $11.61{\pm}6.69$. Somatic symptoms, negative life events (severity), social support were shown as significant predictors of depression. The most influential predictor for depression was somatic symptoms (${\beta}$=.340, $p$ <.001). Conclusion: To prevent and relieve depression in the elderly with mild cognitive impairment, nursing intervention strategies which consider well-balanced physical and psychosocial aspects are needed. In particular, a specific nursing intervention strategy is required to improve physical health of the elderly with mild cognitive impairment.

• Korean Journal of Occupational Health Nursing
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• v.23 no.4
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• pp.197-207
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• 2014

Purpose: The purpose of this study was to investigate the status and characteristics of visiting nurses' management for elders with cognitive impairment living in a community focused on health centers in a metropolitan city and five medium-sized cities. Methods: Data were collected from 47 visiting nurses working in a metropolitan city and 47 visiting nurses working in five medium-sized cities from November to December 2012. Results: There were no statistically significant differences in knowledge, attitudes, and nursing behaviors of cognitive impairment between two groups (F=2.13, p=.148; F=3.64, p=.060; F=0.28, p=.595). Among the elders referred to a physician in a metropolitan city by visiting nurses, 42.4% were diagnosed as mild cognitive impairment and 15.2% were diagnosed as severe dementia. The major intervention programs which visiting nurses currently applied for elders were medication and exercise intervention programs, and the intervention programs which they would want to apply in the future were playing, music and recall intervention programs. Conclusion: The cognitive impairment screening test can be done effectively by visiting nurses. This study also suggests to develop various kinds of intervention programs to improve cognitive function for elders living in a community.