• Culinary science and hospitality research
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• v.21 no.6
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• pp.158-166
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• 2015

The purpose of this study is to verify whether education on the placebo effect has significant impacts on the knowledge of the placebo effect, as well as the intention of healing food intake. For this purpose, 37 experimental group students and 29 control group students participated in the experiment. The results were as follows. First, education on the placebo effect did not appear to have significant impact on the functional value although it did have significant impact on emotional value and nutritional value. Second, knowledge of the placebo effect gained from the education had significant influence on intention of healing food intake. Third, only nutritional value showed a statistically positive (+) impact on intention of healing food intake.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.28 no.1
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• pp.53-67
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• 2015

Objective: The aim of this study was to investigate the wound healing effect of herbal ointment, Gamijaungo, on the burn-induced model. Reports about Gamijaungo on the wound healing effect by local application in mice model or human study have published in the several domestic or internationally, but most are anecdotal and lack solid scientific evidence. Method: We observed the morphologic and histologic changes in the burn-induced mice model. we counted white blood cell and platelet changes. we confirmed VEGF, PI3K and pAkt protein expression by Western blot analysis. Result: In this study, we observed that Gamijaungo showed strong wound healing effects in the morphologic and histologic changes in the burn-induced mice model. Also we found that the significant changes of white blood cell and platelet changes by the treatment of Gamijaungo. In molecular mechanism, we got the strong positive effect by Gamijaungo treatment on angiogenesis, a key process in the formation of the granulation tissue during wound healing. Conclusion: These findings suggest the potential use of Gamijaungo as a therapeutic in thermal burn-induced skin injuries.

• Journal of Physiology & Pathology in Korean Medicine
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• v.24 no.4
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• pp.566-570
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• 2010

This review was conducted to investigate clinical trial trend, clinical effect, and study methods of forest healing. Literature search was performed using the search engines of eight electronic databases from inception to march 2010 without language limitation. The search terms were "forest healing", "forest experience", "forest therapy", "forest treatment", "clinical trial", and "clinical study". Inclusion criteria were randomized controlled trials (RCTs) among all kinds of study searched about forest healing. Selection literature and data extraction was performed by authors(SH Sun and SG Lee) independently. Total three studies were selected finally. The methodological quality in all study was low because of poor reporting. Study indications were metal health, depression, self-esteem, and stress. The scale of studies was very small, which was the level of pilot study. There were no description for obtaining informed consent and being reviewed by Institutional Review Board (IRB), and could be any problems for statistical method in any studies. It is difficult to accept the fact that each studies had the significant effect for study indications in the results of studies. It is concluded that the evidence that health healing have a significant effect is insufficient. Further systematic and methodological study and well-designed clinical trial will be needed.

• Proceedings of the SCSK Conference
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• 2003.09a
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• pp.540-567
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• 2003

Metabolic disease such as diabetes, which is caused by stress or imbalanced diet, has been increasing. A diabetic tend to suffer from a delay or difficulty of wound healing. The extract of SHIKON (SK), that is the root of Lithospermun erythrorhison, has been reported to have an effect on healing for normal wound, but has never studies for intractable wound so far. Therefore we examined the effect of SK extract on wound healing with healing impaired mouse model. Full-thickness round wounds were created on the backs of db/db mice and applied SK, and we observed neovascularization and collagen synthesis, distribution of apoptotic cells, and vascular endothelial growth factor (VEGF)- positive cells in granulation tissue. After two weeks, a number of capillary vessel and collagen synthesis were increased in SK-treated wounds. Infiltration of VEGF-positive neutrophils was also seen in the wound, besides apoptotic fibroblasts and endothelial cells were appeared in the granulation tissue. After three weeks, the wound closed completely with SK-treated but not in control. These results suggest that SK enhanced neovascularization by VEGF and this kind of apoptosis process makes the scar smooth. In this study, it is obvious that SK also accelerates healing of intractable wound.

• Korean Institute of Interior Design Journal
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• v.20 no.5
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• pp.245-253
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• 2011

As interests towards health rapidly increase recently, interests and demand for hospital interior space are increasing as well. Therefore, most of today's hospitals that have been functionally designed are transforming into healing environments that consider psychological aspects, in order to assist patients forget about fear, desperation and have peace of mind. With such creation method of healing environment, natural elements can be applied to spaces in order to allow patients feel vitality, hope and adapt positive thinking, and these can eventually lead to affluent fusion of humans, nature and space. Through case analyses of how natural elements are applied to hospital's interior space, this study understands its characteristics. According to the findings, nature is largely classified into light, water, plant, stone/soil, and its application methods can be classified into center, transition, continuity, division, opening and closure. As evident from case analyses, application of natural elements to hospital's interior space promotes exchanges among patients through community formation, and achieves the effect of spatial concentration and public place. Also, ambiguity of exterior and interior boundary creates a sense of expansion and continuous effect, and can also provide a healing environment that can fully absorb natural environment open to patients. This study aims to be of service when designing hospital's interior space, with its natural element application method for healing environment research, and wishes for continuous studies on healing environments with more diverse methods.

• Journal of Agricultural Extension & Community Development
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• v.30 no.1
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• pp.31-41
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• 2023

This study aims to examine the structural relationships among rurality perception, tourism attitude, and behavioral intention in rural healing tourism. Particularly, this study focused on the mediation effect of attitude. Data were collected from 658 rural healing tourists by online survey. SPSS 28.0 and AMOS 28.0 were used for frequency, exploratory factor, confirmatory factor, and structural equation modeling analyses. The results of structural equation modeling indicate perception of rurality had a positive effect on attitude and behavioral intention. In addition, attitude mediated the relationships between perception of rurality and behavioral intention. The results of this study suggest the importance of understanding the interests and pursuits of rural healing tourists and providing them with the values they want. Since rurality has a direct influence on attracting healing tourists, it is necessary to establish a positive image of rural healing tourism.

• Journal of Agricultural Extension & Community Development
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• v.30 no.3
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• pp.131-141
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• 2023

This study aims to examine the structural relationships among leisure activity, psychological capital, and quality of life in rural healing tourists. Data were collected from 407 workers who had experience in rural healing tourism through an online survey. SPSS 28.0 and AMOS 28.0 were used for frequency, confirmatory factor, and structural equation modelling analysis. The results of structural equation modelling indicate participation in leisure activities had a positive effect on psychological capital. Psychological capital had a positive effect on quality of life. The results of this study suggest that leisure activities play an important role in improving workers' psychological capital. Through rural healing tourism, various outdoor activities, cultural activities, and social interaction with people using rural resources can help improve the psychological capital of workers.

• Journal of the Korean Academy of Clinical Electrophysiology
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• v.6 no.1
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• pp.43-55
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• 2008

The purpose of this study was to investigate the effect of microcurrent stimulation intensity($50{\mu}A,\;100{\mu}A,\;300{\mu}A$ - 5 pps pulse frequency was same) on wound healing in rat. Sixty male Korean rats were randomly divided into 4 groups of 15 for 4 different treatment protocols(none-control group, $50{\mu}A,\;100{\mu}A,\;300{\mu}A$ experimental groups). Experimental 20 mm linear wound were made and all animals in the experimental groups were received microcurrent stimulation once a day for 20 minutes until sacrifice days(1st day, 3rd day, 6th day). A vernier caliper was used to measure a wound healing length and an optical microscope was used to determine any histological changes. The repeated measures two-way ANOVA was used for statistical differences in wound healing length. Experimental results were as follows: 1. In the examination with the naked eye, all groups showed similar changes until 1st day. But from 3rd day, a little intercellular fluid soaked through wound region in control group. In experimental groups, little intercellular fluid soaked through wound region, and swelling and redness did not appear. 2. Wound length of experimental $50{\mu}A$ group was significantly decreased than control group(p<0.001). And in the aspect of application period, wound length was significantly decreased in 3th, 6th day than 1st day and 6th day than 3th day (p<0.001). In conclusion, it has been found that the microcurrent stimulation had a positive effect on wound healing. And $50{\mu}A$ stimulation intensity was more effective than other intensities($100{\mu}A,\;300{\mu}A$) in wound healing. Also, low-intensity microcurrent stimulation was more effective on the purpose of wound healing.

• Journal of Korean Medicine Rehabilitation
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• v.30 no.2
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• pp.19-35
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• 2020

Objectives The aim of this study is to evaluate the fracture healing effect of Jinmu-tang (JM) on femur fractured rats. Methods Rats were randomly divided into 5 groups (normal, control, positive control, JM extract with low concentration and JM extract with high concentration). All group except normal group went through both femur fracture. Normal and control group received no treatment at all. Positive control group were medicated with tramadol (20 mg/kg) once a day for 14 days. Experimental group was orally medicated with JM extract (10 mg/kg for low concentration, 50 mg/kg for high concentration) once a day for 14 days. In order to investigate fracture healing process, plasma and serum were obtained. Also, micro-computed tomography was conducted to see the frature site visually. Immunohistochemistry for transforming growth factor-β1, Ki67, alkaline phosphatase, runt-related transcription factor 2, receptor activator of nuclear factor kappa-β, tartrate resistant acid phosphatase was conducted to observe bone healing progress after 14 days since fracture occured. Aspartate aminotransferase, alanine aminotransferase, blood urea nitrogen and creatinine levels were measured in plasma, for hepatotoxicity and nephrotoxicity of JM extract. Osteocalcin was measured to observe activity of osteoblast. Results Through Micro-CT, more fracture healing was observed on both experimental group than control and positive control group. Through Hematoxylin & Eosin and safranin O staining showed bone cell proliferation and bone formation in the experimental group. RANK was significantly increased in the experimental groups. JM with high concentration showed statistically significant of TGF-β and Osteocalcin. NO, TRAP and ALP were not significantly changed. Liver toxicity was not significantly observed. Creatinine significantly increased in both experimental groups after 28 days. Conclusions As described above, JM extract showed anti-inflammatory effect, promoted fracture healing by stimulating the bone regeneration factor, and showed little hepatotoxicity and nephrotoxicity. In conclusion, JM extract can promote fracture healing and it can be used clinically to patients with fracture.

• Journal of the Korea Concrete Institute
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• v.20 no.1
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• pp.109-116
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• 2008

This study was performed to get information of self-healing mechanism in cement system and the influence of waterproofing admixtures for concrete on self-healing property. For testing, cement paste specimens cured for 7, 14 and 28 days were prepared and crushed into plate-shape pieces. Screened specimens with thickness not more than 1mm were covered with wet rags and cured in a plastic container for 7 and 28 days. After stopping hydration process of the specimens by treatment with acetone, the surfaces of specimens have been contacted with wet rags were analyzed by XRD, DSC, SEM and EDX. The analysis results showed that cement paste has self-healing property and this property is mainly affected by water. Self-healing in cement system is more effective and faster at an early stage of hydration as there is enough content of unreacted cement to make an additional hydration in this period. The results of this study also showed that waterproofing admixtures for concrete have a considerable effect on self-healing of cement pastes; i.e., they improved self-healing effect of cement and, especially, the specimen using admixture C has shown a lot of needle-like or fibrous hydration products which are estimated as ettringite. It is supposed that these ettringite products are effective to enhance self-healing in cement system.