• Title/Summary/Keyword: Head neck

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Neck metastasis of invasive ductal carcinoma of breast causing voice change: a case report (음성변화를 주증상으로 내원한 유방암의 경부연조직 전이환자 1례)

  • Lee, Hyung Min;Park, Ji hoon;Kim, Jin Hwan;Kim, Jung Won;Lee, Dong Jin
    • Korean Journal of Head & Neck Oncology
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    • v.33 no.2
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    • pp.67-70
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    • 2017
  • We present a metastatic carcinoma from the breast to the neck soft tissue around common carotid artery, with a rare finding of voice change. A 60 year-old female patient presented with voice change for 7 months. Neck ultrasound revealed a soft tissue mass between internal jugular vein and common carotid artery. Result of fine needle aspiration biopsy was a metastatic carcinoma. Computed tomography and magnetic resonance image revealed $2.5{\times}3.0cm$ sized irregular marginated soft tissue mass in right lower neck encasing common carotid artery and internal jugular vein. Surgical resection was performed and pathologic result with immunohistochemical analysis confirmed the diagnosis of a metastatic invasive ductal carcinoma originated from breast.

A case of a Spindle cell/pleomorphic lipoma in the lateral neck (측경부에 발생한 방추세포 / 다형성 지방종1예)

  • Kim, Young Yoon;Yoon, Sung Ho;Park, Jong Min;Lee, Dong Hoon
    • Korean Journal of Head & Neck Oncology
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    • v.34 no.1
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    • pp.41-43
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    • 2018
  • The Spindle cell lipoma is a slow-growing benign tumor seen generally in the shoulders, upper back, and back of the neck of male. The Pleomorphic (giant-cell) lipoma is a benign tumor of adipose tissue with atypical histological features. It is mainly seen in the same lesion as the Spindle cell lipoma. The Pleomorphic lipoma is cytogenetically similar to spindle cell lipoma with a consistent loss of chromosome 16q material. For this reason, these two entities are regarded as a similar spectrum in the adipose tumors. Herein, we present a 53-year old man with Spindle cell/pleomorphic lipoma in the lateral neck. Physical and radiologic examinations of the Spindle cell/pleomorphic lipoma in the lateral neck are not specific and preoperative diagnosis is usually difficult. Therefore, clinicians should consider the possibility that Spindle cell/pleomorphic lipoma may occur in the lateral neck mimicking the other more frequently observed lesions.

A case of neck lipoblastoma in a pediatric patient (경부에 발생한 지방모세포종 1예)

  • Kim, Jae Hyung;Choi, ln Hak;Kim, Young-Chan;Baek, Seung-Kuk
    • Korean Journal of Head & Neck Oncology
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    • v.35 no.1
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    • pp.25-27
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    • 2019
  • Lipoblastoma is a rare benign tumor with 80-90% occurring in children less than 3 years of age and 40% occurring in children less than 1 year of age. The most common site of incidence is limb, and then trunk. Neck is the rare site of incidence. The main symptom that the patient complains about is a rapidly growing neck mass without pain. When the size of mass increases, it can cause dyspnea, Horner's syndrome. Lipoblastoma is usually diagnosed as a lipoma in the fine needle aspiration. Since it is not differentiated from lipoma, liposarcoma, and hibernating adenoma in CT and MRI, the definitive diagnosis is histologic diagnosis through surgical resection. The treatment is complete surgical resection. And recurrence rate is 9-25% due to incomplete resection. Authors report this case with a review of literatures since we experienced a case of lipoblastoma diagnosed histopathologically after surgical treatment of neck mass.

Correlation of Clinical Factors with HMGI(Y), p53 and Ki-67 Expression in Squamous Cell Carcinomas of the Head and Neck (두경부 편평세포암에서 HMGI(Y), p53, Ki-67의 발현과 임상인자와의 상관 관계)

  • Rho Young-Soo;Park Jun-Young;Park Il-Seok;Lim Young-Chang;Moon Sung-Ho;Kim Sung-Dong;Hwang Joon-Sik;Kim Duk-Hwan
    • Korean Journal of Head & Neck Oncology
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    • v.18 no.1
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    • pp.11-17
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    • 2002
  • Objectives: Expression of HMGI(Y), a nucleoprotein that binds to A/T rich sequences in the minor groove of the DNA helix, is observed in neoplastically transformed cells but not in normal cells. We have analyzed HMGI(Y), p53 expression and Ki-67 labelling index in squamous cell carcinomas of the head and neck, and evaluated its clinicopathologic significance. Materials and Methods: 40 cases of squamous cell carcinoma of the head and neck were entered on the study of immunohistochemical stains for HMGI(Y), p53 and Ki-67. We analyzed the relationship between HMGI(Y), p53, Ki-67 expression and age, sex, primary tumor site, stage, survival rate, recurrence. Results: HMGI(Y) expression evidenced by immunohistochemical staining was observed in 35 of 40 (87.5%) squamous cell carcinoma of the head and neck. But no significant correlation was observed between HMGI(Y) expression and other clinical factors such as primary site, tumor stage, differenciation, cervical lymph node, metastasis, recurrence and immunohistochemical status of p53. The Ki-67 labelling index was significantly correlated with recurrence and HMGI(Y) expression (p<0.05). Conclusion: This results suggest the Ki-67 is a good prognostic factor and the HMGI(Y) expression plays some roles in carcinogenesis and cellular proliferation of squamous cell carcinoma of the head and neck. HMGI(Y) gene can be used as a cancer marker, the correlation between the gene expression and the prognosis of the cancer patient should be proved in the future studies.