Korean Journal of Head & Neck Oncology (대한두경부종양학회지)

The Korean Society for Head and Neck Oncology (대한두경부종양학회)
권호 표지
DOI QR코드

DOI QR Code

A case of a Spindle cell/pleomorphic lipoma in the lateral neck

측경부에 발생한 방추세포 / 다형성 지방종1예

  • Kim, Young Yoon (Department of Otorhinolaryngology-Head and Neck Surgery, Chonnam National University Medical School & Chonnam National University Hwasun Hospital) ;
  • Yoon, Sung Ho (Department of Otorhinolaryngology-Head and Neck Surgery, Chonnam National University Medical School & Chonnam National University Hwasun Hospital) ;
  • Park, Jong Min (Department of Otorhinolaryngology-Head and Neck Surgery, Chonnam National University Medical School & Chonnam National University Hwasun Hospital) ;
  • Lee, Dong Hoon (Department of Otorhinolaryngology-Head and Neck Surgery, Chonnam National University Medical School & Chonnam National University Hwasun Hospital)
  • 김영윤 (전남대학교 의과대학 화순전남대학교병원 이비인후-두경부외과학교실) ;
  • 윤성호 (전남대학교 의과대학 화순전남대학교병원 이비인후-두경부외과학교실) ;
  • 박종민 (전남대학교 의과대학 화순전남대학교병원 이비인후-두경부외과학교실) ;
  • 이동훈 (전남대학교 의과대학 화순전남대학교병원 이비인후-두경부외과학교실)
  • Received : 2017.11.28
  • Accepted : 2018.03.12
  • Published : 2018.05.30
Download PDF
⟨ Previous Next ⟩

Abstract

The Spindle cell lipoma is a slow-growing benign tumor seen generally in the shoulders, upper back, and back of the neck of male. The Pleomorphic (giant-cell) lipoma is a benign tumor of adipose tissue with atypical histological features. It is mainly seen in the same lesion as the Spindle cell lipoma. The Pleomorphic lipoma is cytogenetically similar to spindle cell lipoma with a consistent loss of chromosome 16q material. For this reason, these two entities are regarded as a similar spectrum in the adipose tumors. Herein, we present a 53-year old man with Spindle cell/pleomorphic lipoma in the lateral neck. Physical and radiologic examinations of the Spindle cell/pleomorphic lipoma in the lateral neck are not specific and preoperative diagnosis is usually difficult. Therefore, clinicians should consider the possibility that Spindle cell/pleomorphic lipoma may occur in the lateral neck mimicking the other more frequently observed lesions.

Keywords

References

  1. Enzinger FM, Harvey DA. Spindle cell lipoma. Cancer. 1975;36:1852-1859. https://doi.org/10.1002/1097-0142(197511)36:5<1852::AID-CNCR2820360542>3.0.CO;2-U
  2. Duve S, Muller-Hocker J, Worret WI. Spindle-cell lipoma of the skin. Am J Dermatopathol. 1995;17:529-533. https://doi.org/10.1097/00000372-199510000-00017
  3. Billings SD, Henley JD, Summerlin D-J, Valkiki S, Tomich CE. Spindle cell lipoma of the oral cavity. Am J Dermatopathol. 2006;28:28-31. https://doi.org/10.1097/01.dad.0000189615.13641.4b
  4. Shmookler BM, Enzinger FM. Pleomorphic lipoma - A benign tumor simulating liposarcoma. A clinicopathologic analysis of 48 cases. Cancer. 1981;47:126-133. https://doi.org/10.1002/1097-0142(19810101)47:1<126::AID-CNCR2820470121>3.0.CO;2-K
  5. Rubin BP, Fletcher CD. The cytogenetics of lipomatous tumours. Histopathology. 1997;30:507-511. https://doi.org/10.1046/j.1365-2559.1997.5680797.x
  6. Reis-Filho JS, Milanezi F, Soares MF, Fillus-Neto J, Schmitt FC. Intradermal spindle cell/pleomorphic lipoma of the vulva: Case report and review of the literature. J Cutan Pathol. 2002;29:59-62. https://doi.org/10.1034/j.1600-0560.2002.290112.x
  7. Jeon JH, Kim JH, Yu DS, Song HJ, Oh CH. A Case of Spindle Cell Lipoma of the Scalp. Korean J Dermatol. 2014;52:430-432.
  8. Dal Cin P, Sciot R, Polito P, Stas M, de Wever I, Comelis A, et al. Lesions of 13q may occur independently of deletion of 16q in spindle cell/pleomorphic lipomas. Histopathology. 1997;31:222-225. https://doi.org/10.1046/j.1365-2559.1997.2450851.x
  9. Reis-Filho JS, Milanezi F, Soares MF, Fillus-Neto J, Schmitt FC. Intradermal spindle cell/pleomorphic lipoma of the vulva: case report and review of the literature. J Cutan Pathol. 2002;29:59-62. https://doi.org/10.1034/j.1600-0560.2002.290112.x
  10. Fletcher CD, Martin-Bates E. Spindle cell lipoma: a clinicopathological study with some original observations. Histopathology. 1987;11:803-817. https://doi.org/10.1111/j.1365-2559.1987.tb01884.x
  11. Diaz-Cascajo C, Borghi S, Weyers W. Pleomorphic lipoma with pseudopapillary structures: a pleomorphic counterpart of pseudoangiomatous spindle cell lipoma. Histopathology. 2000;36:75-476.
  12. Suster S, Fisher C. Immunoreactivity for the human hematopoietic progenitor cell antigen (CD34) in lipomatous tumors. Am J Surg Pathol. 1997;21:195-201. https://doi.org/10.1097/00000478-199702000-00009
  13. Rubin BP, Dal Cin P. The genetics of lipomatous tumors. Semin Diagn Pathol. 2001;18:286-293.
  14. French CA, Mentzel T, Kutzner H, Fletcher CD. Intradermal spindle cell/pleomorphic lipoma. Am J Dermatopathol. 2000;22:496-502. https://doi.org/10.1097/00000372-200012000-00003
  15. Domanski HA, Carlen B, Jonsson K, Mertens F, Akerman M. Distinct cytologic features of spindle cell lipoma. A cytologic-histologic study with clinical, radiologic, electron microscopic, and cytogenetic correlations. Cancer. 2001;93:381-389. https://doi.org/10.1002/cncr.10142