• Ocean and Polar Research
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• 제27권1호
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• pp.109-113
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• 2005

To facilitate estimation of the barbel size of a striped sea catfish, Plotosus lineatus Thumberg total length (TL) and head length (HL) against body weight (BW), HL against TL, and 1st maxillary barbel $(MxBL_1)$, 2nd maxillary barbel $(MxBL_2)$, 1st mandibular barbel $(MnBL_1)$ and 2nd mandibular barbel $(MnBL_2)$ against HL were regressed. The relationship of TL and HL for BW were described by the equation $TL=50.9373BW^{0.3072}\;(r^2=0.9898)$ and $HL=11.2938BW^{0.3144}(r^2=0.9572)$, respectively. The relationship of HL for TL was described by the linear equation $HL=0.1982TL+2.1996(r^2=0.9568)$. The relationship of each barbel for HL described by the equation of $HxBL_1=0.04420HL+0.3105(r^2=0.9615),\;MxBL_2=0.4592HL+0.5321(r^2=0.9519), MnBL_l=0.4057HL+1.9824 (r^2=0.9465)\;and\;MnBL_2=0.4355HL+1.8010(r^2=0.9429)$. Knowledge of the relative growth patterns about each barbel of this species is important for the propagation of seed as stock for large-scale striped sea catfish culture.

• Asian-Australasian Journal of Animal Sciences
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• 제15권1호
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• pp.79-83
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• 2002

The growth and immune responses to endotoxin lipopolysaccharide (LPS) challenge ( $20{\mu}g/kg$) of piglets with and without a iron dextran injection (Fe, 200 mg/head) two days after birth are compared. Sixty-four newborn piglets from eight litters were allocated randomly to one of four treatments. The control received no iron dextran and only saline (Sal) injection on the second and fifteenth day after birth (Sal-Sal). The remaining three groups received Fe-Sal, Sal-LPS, Fe-LPS treatments respectively. On fifteen days of age, blood samples of piglets were taken at 0 h, 1 h, 2 h and 4 d after saline or LPS injection to determine immune functions and blood characteristics. The trial terminated when the pig reached 56 days and the average daily gain of piglets was then measured. Daily gain, serum immunoglobulin G (IgG) concentration and red blood cell counts did not vary significantly among the four groups at any measuring times. Serum tumor necrosis factor-${\alpha}$ (TNF-${\alpha}$) concentration increased sharply 1 h after LPS injection. However, iron injection did not change TNF-${\alpha}$ concentration responds to LPS injection. White blood cell counts of two LPS injection groups were significantly lowered 1 h following the injection. In contrast, serum lactoferrin concentration had increased significantly 1 and 2 h postinjection. Furthermore, iron injection produced no further effects on these two criteria. Iron injection increased the hemoglobin (Hb) concentration of piglets at any measuring time, and LPS injection lowered Hb concentration. In conclusion, a 200 mg/head of iron dextran injection on the second day after birth increased Hb concentration, had no detrimental effect on the immune responses and growth of piglets. Moreover, if creep feed (175 mg Fe/kg feed) is provided from d 7 after birth, the Fe-injection does not contribute to overall performance of piglets and may not be a necessity in practice.

• 대한두경부종양학회지
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• 제14권1호
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• pp.70-75
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• 1998

Tumor growth and metastasis depends on angiogenesis. Vascular endothelial growth factor (VEGF) is a potent mitogen for vascular endothelial cells in vitro and promotes neoangiogenesis in vivo. Objective: Follicular thyroid cancers(FTC) are a vascular tumor and traditionally metastasize via blood vessels. Likely other cancers, angiogenesis may playa important role in FTC. We, therefore, investigated the expression of VEGF and microvascular density by immunohistochemistry in FTC and follicular adenoma(FA). Materials and Methods: Findings of immunohistochemical stainings for VEGF and CD31 were measured by grading scale from +1 to 4+(strongest) and by counting the stained microvessels in 14 FTCs and 14 FAs. Results: 1) Expression of VEGF. a) FTCs have stronger expression than FAs in areas of tumor adjacent to capsule($mean{\pm}SD\:\;3.2{\pm}0.9\;vs\;2.0{\pm}0.9$, p<0.01) and in central area($2.3{\pm}0.7\;vs\;1.3{\pm}0.6$, p<0.01). b) The VEGF expression of capsular area in FTCs are higher than that of central area(p<0.05). 2) Microvascular density by CD31. a) FTCs have more microvessels than FAs in areas of adjacent to capsule($78.9{\pm}27.3\;vs\;38.7{\pm}15.6$, p<0.01) and in central area($75.5{\pm}23.3\;vs\;27.8{\pm}10.7$, p<0.01). b) In FTCs, the number of microvessels of capsular area are more than that of central tumor area, but not significant statistically(p>0.05). Conclusion: The higher expression of VEGF and microvascular density in FTC suggests angiogenesis plays an important role in progression of FTC.

• 대한두경부종양학회지
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• 제27권1호
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• pp.3-11
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• 2011

Hepatocyte growth factor(HGF) and c-Met play an important role in the control of tumor growth and invasion, and they are known to be good prognostic indicators of patient outcome. Epigallocatechin-3-gallate (EGCG) has been shown to have chemopreventive and therapeutic properties by modulating multiple signal pathways regarding the control of proliferation and invasion of cells. In this study, we evaluated the role of c-Met in EGCG-induced inhibition of invasion and apoptosis in an oral cancer cell line. In KB cells where c-Met was knocked down with siRNA, we performed invasion assay and FACS with Annexin V-FITC/PT staining. In addition, we checked the change of mitochondrial membrane potential(MMP) and the generation of reactive oxygen species(ROS). EGCG-induced inhibition of invasiveness was significantly decreased after the knock-down of c-Met. EGCG-induced apoptosis, MMP change and ROS generation was also reduced in c-Met knock-ed-down KB cells. These results suggest that c-Met is involved in EGCG-induced apoptosis and inhibition of invasiveness of oral cancer cell line.

• 대한두경부종양학회지
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• 제7권1호
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• pp.24-34
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• 1991

Lymphangioma is a benign, growth of lymphatic tissue that is present at birth or develops in early childhood, which may cause serious alterations in growth and developmemt. The problems with facial lymphangioma is usually releated directly to their size and to the area of the face which is involved. The lesions themselves may range from small, localized blemishes to huge facial masses involving both soft tissue and underlying bone and causing great distortion and asymmetry. The facial bones are seldom involved, but the natutal evolution of an individual lesion often cannot be accurately predicted when the child is first seen. Any changes in the underlying facial bone could be due either to a direct growth of the lesion into the bone, or secondary to pressure of the lesion growing outside the bone itself. A case of cystic lymphangioma extending from the neck to the tongue is reported. A six-year-old female was admitted because of swelling of the tongue. At that time, the tongue reportedly reached the extraoral size of 7x5x2.5cm and a soft, diffuse swelling of left anterior neck was revealed. The removal of cystic mass including left neck dissection and partial glossectomy were undertaken. The another case of lymphangioma is located on mandibular cheek. A twenty nine-year-old male was admitted because of palpable mass of the left mandibular area and fissure of palate. The radical excision of mass with mandibulectomy of body were undertuken. Thus we reported such a rare case and reviewed the lymphangioma.

• 한국화재소방학회논문지
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• 제30권5호
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• pp.26-35
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• 2016

스프링클러 설비는 화재 발생 시 화재를 초기에 제어 및 진압하는 설비로서 어떠한 화재 분위기에서도 스프링클러 헤드의 작동온도에서 정상적인 동작을 하여야 한다. 그러나 최근 화재성장속도가 느린 화재 발생 장소에서 일부 조기반응형 스프링클러 헤드가 정상적인 동작을 하지 않을 수 있다는 문제가 제기되고 있다. 이에 본 논문에서는 공동주택 침실규모의 모형실험 및 캐비넷형 버너를 이용하여 화재성장속도가 느린 조건을 형성하고 실제 현장에서 배관 내에 가해지는 최소압력인 0.2MPa 이상의 가압수를 공급하여 실험을 진행하였다. 실험결과 국내에서 사용되고 있는 과반수 이상의 플러쉬형 조기반응형 스프링클러 헤드에서 Cold Soldering 현상이 발생되면서 불완전하게 개방되는 것이 확인되었다. 이러한 현상은 화재 조기진압 및 제어에 실패하여 화재확산 및 인명피해의 원인이 될 수 있으므로 추가적인 연구를 통해 국내 형식승인 및 제품검사기준의 보완의 필요할 것으로 판단된다.

• 청정기술
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• 제5권1호
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• pp.78-85
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• 1999

우리나라 고유의 식품산업으로서 최근 급격한 성장을 보이고 있는 김치제조 산업에서 원재료인 배추를 절인 후 염을 세척하는 과정에서 다량의 폐세척수가 발생한다. 본 연구에서는 세척수 사용량의 최적화를 통해 근원적으로 폐세척수 발생량을 저감하기 위한 접근 방법이 고찰되었다. 세척공정을 최적화하기 위한 방법으로 실제공장의 향류식 연속 세척공정 대신 연속 회분식 세척공정을 통한 모사실험이 수행되었으며 실제공정을 효과적으로 모사할 수 있었다. 동일한 원산지 배추에 대해 염절임 후 임의 추출된 표본간의 세척효율의 차이는 미미하였으나 배추의 원산지별 특성에 따라서는 세척효율면에서 상당한 차이를 보였다. 세척수 양을 3.3 L/head(포기)에서 2.7 L/head(포기)까지 감소시켰을 경우에 배추에 남아있는 COD, 탁도, 전기전도도, $Na^+$, $Cl^-$의 농도는 거의 유사하거나 완만하게 증가하는 경향성을 보였으나 세척수량을 2.4 L/head이하로 감소시킴에 따라 세척효율의 악화가 뚜렷이 나타났다. 관능시험에서 세척수의 사용량을 2.7 L/head까지 줄여도 김치의 품질에는 아무 영향이 없었으나 세척수 양을 2.4 L/head이하로 감소시켰을 경우에는 김치의 염분 농도가 너무 높아 젖산 발효율이 저하되었고 짠맛과 함께 이미가 느껴졌다. 결국 제품의 품질에 전혀 영향을 미치지 않는 범위내에서 세척수 사용량을 약 18%까지 절감할 수 있는 것으로 사료되었다.

• Asian-Australasian Journal of Animal Sciences
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• 제14권5호
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• pp.608-614
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• 2001

The effects of castration on growth and body composition of Javan rusa (Cervus timorensis russa) stags were examined at three slaughter ages in three experiments. Castration had no effects on growth rates, or liveweights at periodic weighings, at any stage in Experiments 1 and 2, when the stags were slaughtered at 19 and 13 months of age, respectively. In Experiment 3, monthly liveweights of castrated and entire stags were not significantly different until the stags were 21 months old. From this age, when they had recovered from their first rut season and were in their second spring/early summer, the entires grew more rapidly than the castrates. There were seasonal changes in growth in both treatments, indicating that pasture conditions influenced performance. Liveweights of entires and castrates were similar in stags slaughtered at 13 and 19 months, but castrates were smaller than entires at 25 months. Castration reduced the size of the head and skin, but there was little important effect of castration on body components at any slaughter age. Castration can be recommended as a management tool for rusa stags, especially if the animals are to be slaughtered before they exceed 19 months of age.

• 대한간호학회지
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• 제41권5호
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• pp.613-622
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• 2011

Purposes: Study purpose were to describe growth patterns of premature infants in weight, length and head circumference from birth to 40th week of corrected ages (CA) and to explore factors affecting patterns. Methods: A longitudinal descriptive study was conducted with 267 premature infants. They were categorized into 2 groups; GA group with measurements at birth and the CA group with measurements at CA, which was categorized into 3 groups (group 1-3) by WHO guideline for gestational age (GA) at birth. Results: GA group presented greater measures in all than CA group at same week of life. Among CA groups, group 3 showed the highest measurements, up to 37 weeks of life, though this disappeared at 38-40 weeks. Reversely, group 1 revealed the highest growth rates in all measures, followed by group 2 and group 3. Significant interaction was observed in all measures between week of life and any type of groups. Conclusions: Higher measures in GA group, as well group 3 among CA groups, supported the superiority of intra-uterine environment overriding quality of regimen from NICU. Regardless of growth acceleration, smaller infants remain smaller, indicating that intra-uterine thrifty phenotype may continue at least up to the 40th week of CA.

• Journal of mucopolysaccharidosis and rare diseases
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• 제4권2호
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• pp.42-44
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• 2018

Prader-Willi syndrome (PWS) is a multisystemic complex disorder characterized by hyperphagia and impaired satiety which lead to severe and early obesity. In infancy, hypotonia and poor suck are main problems, and a child goes through Failure-to-thrive. During childhood, clinical manifestations change to food seeking as well as excessive weight gain, short stature, developmental delay, cognitive disability and behavioral problems. Also, growth hormone insufficiency is frequent. Most patients receive the recombinant growth hormone (rGH) therapy that provides improvement in growth, body composition, and physical attributes. The clinical care guideline for rGH therapy in PWS had been noticed in 2013. The rGH therapy helps in body fat, lean body mass, height SDS and head circumference. Also, the rGH therapy helps motor function, psychomotor development and cognition and behavioral issues.In Samsung medical center, there are clinical care guidelines for rGH therapy in PWS and an useful application for the patients. 'Living with PWS', the name of an moblie application for PWS patients, was introduced in the lecture. The application revised to version 2. It was made more convenient to users than in version 1. It helps caregivers to schedule the rGH therapy and to monitor height and weight.