• Title/Summary/Keyword: Hazard maps

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Prediction of Prognosis in Glioblastoma Using Radiomics Features of Dynamic Contrast-Enhanced MRI

  • Elena Pak;Kyu Sung Choi;Seung Hong Choi;Chul-Kee Park;Tae Min Kim;Sung-Hye Park;Joo Ho Lee;Soon-Tae Lee;Inpyeong Hwang;Roh-Eul Yoo;Koung Mi Kang;Tae Jin Yun;Ji-Hoon Kim;Chul-Ho Sohn
    • Korean Journal of Radiology
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    • v.22 no.9
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    • pp.1514-1524
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    • 2021
  • Objective: To develop a radiomics risk score based on dynamic contrast-enhanced (DCE) MRI for prognosis prediction in patients with glioblastoma. Materials and Methods: One hundred and fifty patients (92 male [61.3%]; mean age ± standard deviation, 60.5 ± 13.5 years) with glioblastoma who underwent preoperative MRI were enrolled in the study. Six hundred and forty-two radiomic features were extracted from volume transfer constant (Ktrans), fractional volume of vascular plasma space (Vp), and fractional volume of extravascular extracellular space (Ve) maps of DCE MRI, wherein the regions of interest were based on both T1-weighted contrast-enhancing areas and non-enhancing T2 hyperintense areas. Using feature selection algorithms, salient radiomic features were selected from the 642 features. Next, a radiomics risk score was developed using a weighted combination of the selected features in the discovery set (n = 105); the risk score was validated in the validation set (n = 45) by investigating the difference in prognosis between the "radiomics risk score" groups. Finally, multivariable Cox regression analysis for progression-free survival was performed using the radiomics risk score and clinical variables as covariates. Results: 16 radiomic features obtained from non-enhancing T2 hyperintense areas were selected among the 642 features identified. The radiomics risk score was used to stratify high- and low-risk groups in both the discovery and validation sets (both p < 0.001 by the log-rank test). The radiomics risk score and presence of isocitrate dehydrogenase (IDH) mutation showed independent associations with progression-free survival in opposite directions (hazard ratio, 3.56; p = 0.004 and hazard ratio, 0.34; p = 0.022, respectively). Conclusion: We developed and validated the "radiomics risk score" from the features of DCE MRI based on non-enhancing T2 hyperintense areas for risk stratification of patients with glioblastoma. It was associated with progression-free survival independently of IDH mutation status.

A Comparative Assessment of the Efficacy of Frequency Ratio, Statistical Index, Weight of Evidence, Certainty Factor, and Index of Entropy in Landslide Susceptibility Mapping

  • Park, Soyoung;Kim, Jinsoo
    • Korean Journal of Remote Sensing
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    • v.36 no.1
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    • pp.67-81
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    • 2020
  • The rapid climatic changes being caused by global warming are resulting in abnormal weather conditions worldwide, which in some regions have increased the frequency of landslides. This study was aimed to analyze and compare the landslide susceptibility using the Frequency Ratio (FR), Statistical Index, Weight of Evidence, Certainty Factor, and Index of Entropy (IoE) at Woomyeon Mountain in South Korea. Through the construction of a landslide inventory map, 164 landslide locations in total were found, of which 50 (30%) were reserved to validate the model after 114 (70%) had been chosen at random for model training. The sixteen landslide conditioning factors related to topography, hydrology, pedology, and forestry factors were considered. The results were evaluated and compared using relative operating characteristic curve and the statistical indexes. From the analysis, it was shown that the FR and IoE models were better than the other models. The FR model, with a prediction rate of 0.805, performed slightly better than the IoE model with a prediction rate of 0.798. These models had the same sensitivity values of 0.940. The IoE model gave a specific value of 0.329 and an accuracy value of 0.710, which outperforms the FR model which gave 0.276 and 0.680, respectively, to predict the spatial landslide in the study area. The generated landslide susceptibility maps can be useful for disaster and land use planning.

Determination of seismic hazard and soil response of a critical region in Turkey considering far-field and near-field earthquake effect

  • Sonmezer, Yetis Bulent;Celiker, Murat
    • Geomechanics and Engineering
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    • v.20 no.2
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    • pp.131-146
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    • 2020
  • Evaluation of earthquake impacts in settlements with a high risk of earthquake occurrence is important for the determination of site-specific dynamic soil parameters and earthquake-resistant structural planning. In this study, dynamic soil properties of Karliova (Bingol) city center, located near to the intersection point of the North Anatolian Fault Zone and the East Anatolian Fault Zone and therefore having a high earthquake risk, were investigated by one-dimensional equivalent linear site response analysis. From ground response analyses, peak ground acceleration, predominant site period, 0.2-sec and 1-sec spectral accelerations and soil amplification maps of the study area were obtained for both near-field and far-field earthquake effects. The average acceleration spectrum obtained from analysis, for a near-field earthquake scenario, was found to exceed the design spectra of the Turkish Earthquake Code and Eurocode 8. Yet, the average acceleration spectrum was found to remain below the respective design spectra of the two codes for the far-field earthquake scenario. According to both near- and far-field earthquake scenarios in the study area, the low-rise buildings with low modal vibration durations are expected to be exposed to high spectral acceleration values and high-rise buildings with high modal vibration durations will be exposed to lower spectral accelerations. While high amplification ratios are observed in the north of the study area for the near-distance earthquake scenario, high amplification ratios are observed in the south of the study area for the long-distance earthquake scenario.

Industrial Safety Risk Analysis Using Spatial Analytics and Data Mining (공간분석·데이터마이닝 융합방법론을 통한 산업안전 취약지 등급화 방안)

  • Ko, Kyeongseok;Yang, Jaekyung
    • Journal of Korean Society of Industrial and Systems Engineering
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    • v.40 no.4
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    • pp.147-153
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    • 2017
  • The mortality rate in industrial accidents in South Korea was 11 per 100,000 workers in 2015. It's five times higher than the OECD average. Economic losses due to industrial accidents continue to grow, reaching 19 trillion won much more than natural disaster losses equivalent to 1.1 trillion won. It requires fundamental changes according to industrial safety management. In this study, We classified the risk of accidents in industrial complex of Ulju-gun using spatial analytics and data mining. We collected 119 data on accident data, factory characteristics data, company information such as sales amount, capital stock, building information, weather information, official land price, etc. Through the pre-processing and data convergence process, the analysis dataset was constructed. Then we conducted geographically weighted regression with spatial factors affecting fire incidents and calculated the risk of fire accidents with analytical model for combining Boosting and CART (Classification and Regression Tree). We drew the main factors that affect the fire accident. The drawn main factors are deterioration of buildings, capital stock, employee number, officially assessed land price and height of building. Finally the predicted accident rates were divided into four class (risk category-alert, hazard, caution, and attention) with Jenks Natural Breaks Classification. It is divided by seeking to minimize each class's average deviation from the class mean, while maximizing each class's deviation from the means of the other groups. As the analysis results were also visualized on maps, the danger zone can be intuitively checked. It is judged to be available in different policy decisions for different types, such as those used by different types of risk ratings.

Development of Probabilistic Flood Risk Map Considering Uncertainty of Levee Break (하천제방 붕괴의 불확실성을 고려한 확률론적 홍수위험지도 개발)

  • Nam, Myeong-Jun;Lee, Jae-Young;Lee, Chang-Hee
    • Journal of Convergence for Information Technology
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    • v.9 no.11
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    • pp.125-133
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    • 2019
  • In this paper, probabilistic flood risk maps were produced for levee break caused by possible flood scenarios. The results of the previous studies were employed for flood stages corresponding to hydrological extreme event quantified uncertainties and then predicted the location of a levee breach. The breach width was estimated by combining empirical equation considered constant width and numerical modeling considered uncertainties on compound geotechnical component. Accordingly, probabilistic breach outflow was computed and probabilistic inundation map was produced by 100 runs of 2D inundation simulation based on reliability analysis. The final probabilistic flood risk map was produced by combining probabilistic inundation map based on flood hazard mapping methodology. The outcomes of the study would be effective in establishing specified emergency actin plan (EAP) and expect to suggest more economical and stable design index.

A Property of Seismic Response with Log-normal Distribution at SDOF Structure (단자유도계 구조물의 로그정규분포 지진응답 특성)

  • Chung, Youn-In;Kim, Koon-Chan;Chey, Min-Ho
    • Journal of the Korea Convergence Society
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    • v.10 no.11
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    • pp.303-308
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    • 2019
  • This study suggests a method for deriving earthquake response based on log-normal distribution in order to obtain realistic and reliable probability and statistical seismic response of structures. The development of three earthquake suites were presented, with a brief description of 2%, 10%, and 50% in 50 years probability of exceedance according the USGS Los Angeles probabilistic seismic hazard maps. In order to analyze the basic dynamic behavior, a Single-Degree-of-Freedom (SDOF) structure was selected and the seismic response spectrum representing the response of each natural period was plotted. Overall, the mean response values presented through the log-normal distribution is lower than the standard normal distribution. Thus, it is considered that the former method can be provided as the effective cost on performance-based seismic design more than the latter one.

Review of earthquake-induced landslide modeling and scenario-based application

  • Lee, Giha;An, Hyunuk;Yeon, Minho;Seo, Jun Pyo;Lee, Chang Woo
    • Korean Journal of Agricultural Science
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    • v.47 no.4
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    • pp.963-978
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    • 2020
  • Earthquakes can induce a large number of landslides and cause very serious property damage and human casualties. There are two issues in study on earthquake-induced landslides: (1) slope stability analysis under seismic loading and (2) debris flow run-out analysis. This study aims to review technical studies related to the development and application of earthquake-induced landslide models (seismic slope stability analysis). Moreover, a pilot application of a physics-based slope stability model to Mt. Umyeon, in Seoul, with several earthquake scenarios was conducted to test regional scale seismic landslide mapping. The earthquake-induced landslide simulation model can be categorized into 1) Pseudo-static model, 2) Newmark's dynamic displacement model and 3) stress-strain model. The Pseudo-static model is preferred for producing seismic landslide hazard maps because it is impossible to verify the dynamic model-based simulation results due to lack of earthquake-induced landslide inventory in Korea. Earthquake scenario-based simulation results show that given dry conditions, unstable slopes begin to occur in parts of upper areas due to the 50-year earthquake magnitude; most of the study area becomes unstable when the earthquake frequency is 200 years. On the other hand, when the soil is in a wet state due to heavy rainfall, many areas are unstable even if no earthquake occurs, and when rainfall and 50-year earthquakes occur simultaneously, most areas appear unstable, as in simulation results based on 100-year earthquakes in dry condition.

The Effect of Cognitive Impairment on the Association Between Social Network Properties and Mortality Among Older Korean Adults

  • Eunji Kim;Kiho Sung;Chang Oh Kim;Yoosik Youm;Hyeon Chang Kim
    • Journal of Preventive Medicine and Public Health
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    • v.56 no.1
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    • pp.31-40
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    • 2023
  • Objectives: This study investigated the effect of cognitive impairment on the association between social network properties and mortality among older Korean adults. Methods: This study used data from the Korean Social Life, Health, and Aging Project. It obtained 814 older adults' complete network maps across an entire village in 2011-2012. Participants' deaths until December 31, 2020 were confirmed by cause-of-death statistics. A Cox proportional hazards model was used to assess the risks of poor social network properties (low degree centrality, perceived loneliness, social non-participation, group-level segregation, and lack of support) on mortality according to cognitive impairment. Results: In total, 675 participants (5510.4 person-years) were analyzed, excluding those with missing data and those whose deaths could not be verified. Along with cognitive impairment, all social network properties except loneliness were independently associated with mortality. When stratified by cognitive function, some variables indicating poor social relations had higher risks among older adults with cognitive impairment, with adjusted hazard ratios (HRs) of 2.12 (95% confidence interval [CI], 1.34 to 3.35) for social nonparticipation, 1.58 (95% CI, 0.94 to 2.65) for group-level segregation, and 3.44 (95% CI, 1.55 to 7.60) for lack of support. On the contrary, these effects were not observed among those with normal cognition, with adjusted HRs of 0.73 (95% CI, 0.31 to 1.71), 0.96 (95% CI, 0.42 to 2.21), and 0.95 (95% CI, 0.23 to 3.96), respectively. Conclusions: The effect of social network properties was more critical among the elderly with cognitive impairment. Older adults with poor cognitive function are particularly encouraged to participate in social activities to reduce the risk of mortality.

A study on development of CRM chrysotile in soil (토양 중 백석면 표준물질 개발에 관한 연구)

  • Choi, Yun-Ho;Kwon, Ye-Bin;Lee, Jin-Wook;Kim, Nam-Jun;Jeong, Min-Jong;Hwang, Beom-Goo;Lee, Jae-Hyung;Sun, Yle-Shik;Kim, Bak-Gil
    • Analytical Science and Technology
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    • v.26 no.1
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    • pp.91-98
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    • 2013
  • Interested in NOA (Naturally Occurring Asbestos), Korea as well as the USA has been making geologic maps of asbestos distributed mines and surrounding areas, restoring mines, evaluating hazard, and so on. The result can be used to improve the reliability of analysts and analysis institutions by judging the amount of asbestos and set up PLM(Polarizing Light Microscope) information by analyzing in soil. The certification value of 2 kinds of CRM(Certified Reference Material) was performed by counting total 400 points with EPA 600-R-93-116 method using by PLM. The following is the result of homogeneity and stability of 2 kinds of manufactured CRM analyzed by ANOVA (Analysis of variance) and Regression Analysis. Based on the analyzation, the results are satisfied with homogeneity and long-term stability. The analyzed certification value of CRM includes the range of minimum and maximum value of point counting result for chrysotile; low concentration-1% (range, 0.25~3.00), high concentration-4% (range, 2.25~5.50).

Landslide Susceptibility Mapping Using Ensemble FR and LR models at the Inje Area, Korea (FR과 LR 앙상블 모형을 이용한 산사태 취약성 지도 제작 및 검증)

  • Kim, Jin Soo;Park, So Young
    • Journal of Korean Society for Geospatial Information Science
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    • v.25 no.1
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    • pp.19-27
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    • 2017
  • This research was aimed to analyze landslide susceptibility and compare the prediction accuracy using ensemble frequency ratio (FR) and logistic regression at the Inje area, Korea. The landslide locations were identified with the before and after aerial photographs of landslide occurrence that were randomly selected for training (70%) and validation (30%). The total twelve landslide-related factors were elevation, slope, aspect, distance to drainage, topographic wetness index, stream power index, soil texture, soil sickness, timber age, timber diameter, timber density, and timber type. The spatial relationship between landslide occurrence and landslide-related factors was analyzed using FR and ensemble model. The produced LSI maps were validated and compared using relative operating characteristics (ROC) curve. The prediction accuracy of produced ensemble LSI map was about 2% higher than FR LSI map. The LSI map produced in this research could be used to establish land use planning and mitigate the damages caused by disaster.