• Safety and Health at Work
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• v.10 no.4
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• pp.428-436
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• 2019

Background: Metalworking fluids (MWFs) are mixtures with inhalation exposures as mists, dusts, and vapors, and dermal exposure in the dispersed and bulk liquid phase. A quantitative risk assessment was performed for exposure to MWF and respiratory disease. Methods: Risks associated with MWF were derived from published studies and NIOSH Health Hazard Evaluations, and lifetime risks were calculated. The outcomes analyzed included adult onset asthma, hypersensitivity pneumonitis, pulmonary function impairment, and reported symptoms. Incidence rates were compiled or estimated, and annual proportional loss of respiratory capacity was derived from cross-sectional assessments. Results: A strong healthy worker survivor effect was present. New-onset asthma and hypersensitivity pneumonitis, at 0.1 mg/㎥ MWF under continuous outbreak conditions, had a lifetime risk of 45%; if the associated microbiological conditions occur with only 5% prevalence, then the lifetime risk would be about 3%. At 0.1 mg/㎥, the estimate of excess lifetime risk of attributable pulmonary impairment was 0.25%, which may have been underestimated by a factor of 5 or more by a strong healthy worker survivor effect. The symptom prevalence associated with respiratory impairment at 0.1 mg/㎥ MWF was estimated to be 5% (published studies) and 21% (Health Hazard Evaluations). Conclusion: Significant risks of impairment and chronic disease occurred at 0.1 mg/㎥ for MWFs in use mostly before 2000. Evolving MWFs contain new ingredients with uncharacterized long-term hazards.

• Journal of the Korean Society of Hazard Mitigation
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• v.1 no.1 s.1
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• pp.81-90
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• 2001

This paper presents the results of the parametric study on the longitudinal behavior of 2-span continuous railway bridge. To perform the main objective of this paper, the effects of pier shaft stiffness, pier height, the size of pier foundation, and the bearing stiffness on the longitudinal behavior of the bridges are studied. Within the limits of this study, the research result has revealed that the variation of the fixed pier is more effective than that of the moved pier. In addition, the control of the hearing stiffness is much less expensive than that of any other parameters.

• Journal of the Korean Society of Hazard Mitigation
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• v.9 no.2
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• pp.53-57
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• 2009

The dividing flow in an open channel has a number of distinctive characteristics. One of these is that the separation zone interacts with a secondary motion along the inner wall of a branch channel, generating sediment accumulation. To investigate this phenomenon, a two-dimensional numerical model based on the shallow-water equations, RMA2, which calculates water surface elevations and horizontal-velocity components, was used to analyze the dividing flow. The obtained numerical results fully coincide with the laboratory measurements reported by Hsu et al.(2002). For the analysis of the numerical results, a separation zone-discharge rate relationship was proposed. To reduce the size of a separation zone, the topographies of diagonal and curved edges were proposed, smoothly connecting the upstream corner to branch channel.

• Journal of the Korean Data and Information Science Society
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• v.21 no.2
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• pp.201-209
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• 2010

Due to the dramatic increase of mortality from ischemic heart disease (IHD) during the last decade, it is highly warranted to present the effective prevention strategy. Therefore this study identified the major risk factors of IHD over 10 years of follow-up among 2,268,018 participants of National Health Insurance Exam in 1996 with Cox proportional hazard model. In men, BMI, blood pressure, smoking were significantly associated with IHD, whereas hypertension, perceived health status and ${\gamma}$-GTP were related with IHD in women.

• Journal of the Korean GEO-environmental Society
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• v.20 no.6
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• pp.15-22
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• 2019

In this study, the hazard areas are identified by using the Newmark displacement model, which is a predictive model for identifying the areas at risk of landslide triggered by earthquakes, based on the results of field survey and laboratory test, and literature data. The Newmark displacement model mainly utilizes earthquake and slope related data, and the safety of slope stability derived from LSMAP, which is a landslide prediction program. Backyang Mt. in Busan where the landslide has already occurred, was chosen as the study area of this research. As a result of this study, the area of landslide prone zone identified by using the Newmark displacement model without earthquake factor is about 1.15 times larger than that identified by using LSMAP.

• Journal of Korean Neurosurgical Society
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• v.64 no.5
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• pp.763-775
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• 2021

Objective : Hemorrhagic transformation (HT) can be occurred after acute cerebral infarction. HT can worse symptoms in severe cases and adversely affect long-term prognosis. As bone and vascular smooth muscle are composed of type 1 collagen, we aimed to identify a potential relationship between bone mineral density (BMD) and HT after acute cardioembolic stroke. Methods : As an indicator of BMD, we used mean frontal skull Hounsfield unit (HU) values on brain computed tomography (CT). Multivariative hazard ratios were calculated using Cox regression analysis to identify whether the osteoporotic condition was an independent predictor of HT after acute cardioembolic stroke. Results : This 11-year analysis enrolled 506 patients who diagnosed as acute cardioembolic infarction. The first tertile of skull HU value was an independent predictor of HT development compared to the third tertile (hazard ratio, 2.12; 95% confidence interval, 1.13-3.98; p=0.020). We observed no interactions between age and skull HU with respect to HT statistically. Conclusion : The results of this study revealed an association between osteoporotic conditions and HT development after acute cardioembolic stroke. A convenient method to measure the cancellous bone HU value of the frontal skull using brain CT images may be useful for predicting HT in patients with acute cerebral infarction.

• Journal of the Korean Geotechnical Society
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• v.23 no.3
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• pp.111-121
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• 2007

The paper presents a reliability-based method that can capture the impact of uncertainty of seismic loadings. The proposed method incorporates probabilistic concepts into the classical limit equilibrium and the Newmark-type deformation techniques. The risk of damage is then computed by Monte Carlo simulation. Random process and RMS hazard method are introduced to produce seismic motions and also to use them in the seismic slope analyses. The geotechnical variability and sampling errors are also considered. The results of reliability analyses indicate that in a highly seismically active region, characterization of earthquake hazard is the more critical factor, and characterization of soil properties has a relatively small effect on the computed risk of slope failure and excessive slope deformations. The results can be applicable to both circular and non-circular slip surface failure modes.

• The Journal of the Korean life insurance medical association
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• v.27 no.2
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• pp.85-95
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• 2008

When an insurance company receives an application for life or health insurance, the company must evaluate the degree of risk the individual for insurance coverage presents before the company agrees to issue the policy. A medical factor is a physical or psychological characteristic that may increases a hazard. A financial factor is financial information that is taken into account by underwriter to determine if a person is applying for more than he/she reasonably needs or can afford. A personal factor is a lifestyle choice. There are several medical risk selection systems in Korean life insurance market. They are attending physician's statement, direct examination by insurance doctors, and paramedic examination. However there is some dissatisfaction of current system. It is possible that cooperation of part-time insurance doctors system may be one of useful system of medical risk selection. Improvement of medical risk selection system will be an important matter of profitability of insurance company and it will contribute to sound life insurance system.

• Earthquakes and Structures
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• v.8 no.5
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• pp.1091-1111
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• 2015

Base isolation is an effective method for protecting structures against earthquake hazard. It elongates the period of vibration and introduces supplemental damping to the structural system. The stiffness, damping and displacement are coupled forcing the code seismic design procedure to be unnecessarily complicated. In addition, the force reduction factor -a key parameter in the design procedurehas not been well addressed by seismic design codes at the high levels of damping due to the pronounced difference between pseudo and actual accelerations. In this study, a comparison has been conducted to evaluate eight different methods, in the literature, for calculating the force reduction factor due to damping. Accordingly, a simplified seismic analysis procedure has been proposed based on the well documented N2 method. Comprehensive analysis has been performed for base-isolated structure models for direct application and verification of the proposed procedure. The results have been compared with those of the European code EC8, the nonlinear time history analysis and investigations in the literature, where good agreement has been reported. In addition, a discussion has been elaborated for the resulted response of the base-isolated structure models with respect to the dynamic characteristics of the base isolation system.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.7
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• pp.4195-4198
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• 2013

Background and Objective: Though researched for years, the prognostic role of hypoxia-inducible factor 1 alpha (HIF-$1{\alpha}$) in gastric cancer is still controversial. We thus undertook a systematic review to assess the relationship. Method: A systematically literature search of Pubmed, Embase, Web of Science, China Biological Medicine Disc and Cochrane Library was undertaken in February 2013, and the reference lists of articles were retrieved. Results: 12 trials (1,555 participants) were included to assess the association between HIF-$1{\alpha}$ expression and survival. Summary hazard ratios (HRs) were calculated. HIF-$1{\alpha}$ expression was significantly correlated with poor overall survival of gastric cancer patients (HR=1.34, 95%CI: 1.13-1.58; P=0.0009), but not with poor disease free survival of gastric cancer patients (HR=1.67, 95%CI: 0.99-2.82; P=0.06). Conclusion: HIF-$1{\alpha}$ was associated with poor OS, but not DFS, especially for Asian patients. But studies evaluating relationships of HIF-$1{\alpha}$ with OS and DFS in non-Asian gastric cancer patients appear needed.