• Journal of the Korean Society of Hazard Mitigation
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• v.11 no.1
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• pp.7-13
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• 2011

Accurate response analysis of long span bridges subjected to seismic excitation is important for earthquake hazard mitigation. In this paper, the performance of a typical four span continuous reinforced concrete bridge model subjected to asynchronous multiple seismic excitations at the supports is investigated in both the time and frequency domains and the results are compared with that from a relevant uniform support excitations. In the time domain analysis, a linear modal superposition approach is used to compute the peak response values. In the frequency domain analysis, linear random vibration theory is used to determine the root mean square response values where the cross correlation effects between the modal and the support excitations on the seismic response of the bridge model are included. From the two sets of results, a practical range of peak factors which are defined to be the ratio of peak and the root mean square responses are suggested for displacements and forces in members. With reliable practical values of peak factors, the frequency domain analysis is preferred for the performance based design of bridges because of the computational advantage and the generality of the results as the time domain analysis only yields results for the specific excitation input.

• Korean Journal of Ophthalmology
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• v.32 no.6
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• pp.470-477
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• 2018

Purpose: To investigate the relationship between the progression of visual field (VF) loss and changes in lamina cribrosa depth (LCD) as determined by spectral-domain optical coherence tomography (SD-OCT) enhanced depth imaging in patients with primary open angle glaucoma (POAG). Methods: Data from 60 POAG patients (mean follow-up, $3.5{\pm}0.7$ years) were included in this retrospective study. The LCD was measured in the optic disc image using SD-OCT enhanced depth imaging scanning at each visit. Change in the LCD was considered to either 'increase' or 'decrease' when the differences between baseline and the latest two consecutive follow-up visits were greater than the corresponding reproducibility coefficient value ($23.08{\mu}m$, as determined in a preliminary reproducibility study). All participants were divided into three groups: increased LCD (ILCD), decreased LCD (DLCD), and no LCD change (NLCD). The Early Manifest Glaucoma Trial criteria were used to define VF deterioration. Kaplan-Meier survival analysis and Cox's proportional hazard models were performed to explore the relationship between VF progression and LCD change. Results: Of the 60 eyes examined, 35.0% (21 eyes), 28.3% (17 eyes), and 36.7% (22 eyes) were classified as the ILCD, DLCD, and NLCD groups, respectively. Kaplan-Meier survival analysis showed a greater cumulative probability of VF progression in the ILCD group than in the NLCD (p < 0.001) or DLCD groups (p = 0.018). Increased LCD was identified as the only risk factor for VF progression in the Cox proportional hazard models (hazard ratio, 1.008; 95% confidence interval, 1.000 to 1.015; p = 0.047). Conclusions: Increased LCD was associated with a greater possibility of VF progression. The quantitative measurement of LCD changes, determined by SD-OCT, is a potential biomarker for the prediction of VF deterioration in patients with POAG.

• Journal of Hydrogen and New Energy
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• v.34 no.4
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• pp.381-387
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• 2023

The risk assessment (safety assessment) must be performed to verify the risks during operation and installation of the hydrogen system and to ensure safe design and operation. Among them, hazard and operability study (HAZOP), a qualitative risk assessment, is most often used to discover risk factors and secure safety. However, in HAZOP performance, there is a difference in the level of evaluation results depending on the level and experience of the evaluator, and there is a high possibility that subjective results will be derived. This study aims to develop a risk factor library that can list and provide information on potential risk factors in order to solve these problems when performing HAZOP, reduce risk factors that are omitted or overlooked.

• Journal of Veterinary Clinics
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• v.40 no.6
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• pp.438-444
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• 2023

The aim of this study was to analyze the learning curve of a low-volume veterinary surgeon for laparoscopic salpingectomy of Asiatic black bear. A total of 66 Asiatic black bears (Ursus thibetanus) were presented for sterilization using laparoscopic salpingectomy. These 66 bears were divided into three groups of 22 bears according to the order of surgery (A, B, and C groups, 22 bears per group). One veterinarian performed laparoscopic salpingectomy. There was no significant difference in age, body weight, or crown-rump length between groups. The hazard of completion for salpingectomy by 5 minutes was higher (p < 0.0001) in B and C groups than A group, whereas the hazard was not significant different between B and C groups. The factor that affected the hazard of completing salpingectomy by 5 minutes was heart rate, not age or weight. Operation time was 12.61 ± 8.04 minutes for group A, 5.35 ± 4.38 minutes for group B, and 2.80 ± 1.16 minutes for group C. The operation time for salpingectomy shortened over time. However, significant difference in operation time was present only between groups A and C (p = 0.001). The operation time for laparoscopic salpingectomy decreased rapidly for the first 7 bears (p < 0.05). It then decreased gradually until the 66th case. Operation time of laparoscopic salpingectomy was significantly decreased and stabilized after 33 cases (p < 0.05). As a result, the number of bears required for a low-volume veterinary surgeon to be proficient in laparoscopic salpingectomy is 33 or more.

• Annals of Occupational and Environmental Medicine
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• v.34
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• pp.24.1-24.13
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• 2022

Background: In modern society, depression is serious issue that causes socioeconomic and family burden. To decrease the incidence of depression, risk factors should be identified and managed. Among many risk factors for depression, this study examined socioeconomic risk factors for depression. Methods: We utilized first (2006), second (2008), and third (2010)-wave data from the Korean Longitudinal Study of Aging (KLoSA). Depressive symptom was measured with the 10-item Center for Epidemiological Studies Depression Scale, Short Form (CES-D-10) in the survey in 2008 and 2010. Three risk factors including job security, employment type and monthly income were measured in the survey in 2006. The association between risk factors and depressive symptom was analyzed by Cox proportional-hazard model. Results: We analyzed data from 1,105 workers and hazard ratios (HRs) for 3 risk factors were significant entirely. In addition, regular worker with high income group is the most vulnerable group of poor job insecurity on depression among male workers (HR: 1.73; 95% confidence interval [CI]: 1.07-2.81). Finally, HRs for 7 groups who had at least 1 risk factor had higher HRs compared to groups who had no risk factors after stratifying 3 risk factors. In the analysis, significantly vulnerable groups were total 5 groups and the group who had highest HR was temporary/daily workers with poor job security (HR: 2.51; 95% CI: 1.36-4.64). The results concerning women, regardless of job type, were non-significant. Conclusions: This study presented one or more risk factors among poor job security, low income, temporary/daily employment type increase hazard for depressive symptom in 2 or 4 years after the exposure. These results inform policy to screen for and protect against the risk of depression in vulnerable groups.

• The Journal of Engineering Geology
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• v.4 no.1
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• pp.43-55
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• 1994

Two thematic maps on environmental geology were produced in the Cheong-Ju area, with aids of GIS technique. They are landslide hazards & risk maps and cut-fill maps. The models of environmental geology map and digital database were established for creation of these maps by means of cartographic simulation in GIS. These special maps are very important for understanding the environmental characteristics of the study area, and can be applied in the establishment of the regional land use planning. For instance, the landslide hazard and risk map can play very important role in the road design, and cut- fill map in the construction work in the area. The scoring system for landslide analysis was developed through the evaluation of each environmental geologic factor in relation to the others and reflects the relative imporatance of each factor. The excavation index(easy, intermediate and difficult) was evaluated through cut-fill analysis, and they can be very useftil for assessing the degree of excavation difficulty.

• Journal of the Korean Society of Hazard Mitigation
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• v.10 no.5
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• pp.109-116
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• 2010

Infiltration and the rising level of groundwater caused by rainfall are a major cause of the landslide and sliding. In order to secure the safety factor of slope, the slope stabilization and reinforcement works are used to enhance consistency. Nailing, Slope Drainage method and the surface vegetation measures can be simultaneously applied in the Mass Nail method, which is also environmental friendly reinforcement method. To demonstrate the reinforcement effect of a strengthened slope by Mass Nail, the changes in water contents by rainfall were considered while performing Scale Model Test. As a result, safety factor of reinforced slope was about 1.4~2.3 times increased on the unstrength slope. In the case of increasing water content 10% to 22%, The maximum stress was reduced to 12%~24% at the average rate of 18% on the unstrength slope and the reinforced slope by the Mass Nail Method was reduced to 4%~23% at the average rate of 14%.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.6
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• pp.2903-2908
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• 2012

Background: Matrix metalloproteinase-9 (MMP-9) is associated with disruption of basement membranes of blood vessels and promotion of metastasis through the lymphatics. However, its prognostic value for survival in patients with gastric cancer remains controversial. Method: We therefore conducted a meta-analysis of the published literature in order to clarify the impact of MMP-9. Clinical studies were selected for further analysis if they provided an independent assessment of MMP-9 in gastric cancer and reported analysis of survival data according to MMP-9 expression. Results: A total of 11 studies, covering 1700 patients, were included for meta-analysis. A summary hazard ratio (HR) of all studies and sub-group hazard ratios were calculated. The combined HR suggested that a positive MMP-9 expression had an impact on overall survival: 1.25 (95% confidence interval 1.11-1.40) in all eligible studies; 1.13 (1.06-1.20) in 8 studies detecting MMP-9 by immunohistochemistry; 1.36 (1.12-1.65) in 7 studies from Asia. Only one study for DFS showed a significant impact on disease free survival (HR 1.73, 95%CI 1.27-2.34). Conclusions: Our findings suggested that MMP-9 protein expression might be a factor for a poor prognosis in patients with gastric cancer. However, the association was rather weak, so that more prospective studies should further explore the prognostic impact of MMP-9 mRNA and correlations between MMP-9 and clinicopathological characteristics.

• Journal of the Korean Society of Hazard Mitigation
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• v.2 no.1 s.4
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• pp.119-126
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• 2002

This paper presents the appropriateness for using high strength reinforcement according to the use of high strength concrete. Nine flexural tests were conducted on full-scale beam specimens according to the concrete strength, reinforcement strength and reinforcement ratio as main variable. The structural behavior was analyzed due to the flexural strength, stress-strain curve, deflections at yielding and fracture point, crack appearance and ductility factor. The member with high-strength reinforcements showed large deflection at yielding point and this was analyzed as a main cause to decrease the ductility factor. Structural behavior after yielding point, however, showed similarity to behavior of members with normal strength reinforcements of same stiffness. It was found that in the case of using reinforcements of $5500kgf/cm^2$ strength, the combination with concrete of $800kgf/cm^2$ strength demonstrated the great appropriateness which can increase the flexural capacity without any reduction of maximum reinforcement ratio.

• Journal of the Korean Society of Hazard Mitigation
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• v.8 no.3
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• pp.149-155
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• 2008

To evaluate the formulae for the stability of riprap, the formulae of Isbash, California division of highway, Netherlands, ASCE, Pilarczk, and Maynord are comparatively analysed with the experimental results. The critical velocity which initiates the motion of riprap is increased with the weight and the size in diameter and the riprap size with water depth, Froude number, shear velocity with mean velocity, Shields parameter have great correlation with them. The results by 6 formulae are overestimated in riprap size in diameter and the result by Maynord formula proposed by U.S. Army Corps of Engineers estimates rather correct. The results by Isbash, Netherlands, and Pilarczk are overestimated in riprap weight but the result by California division of highway formula coincides with experimental result. In the experimental results of model riprap artificially made by gypsum with light weight density, the critical velocity is increased with shape factors. The critical velocity appears greater in regular arrangement of model riprap than in random arrangement of it. Therefore the shape factor and the degree of interlocking are an important parameters in riprap stability.