• 제목/요약/키워드: Harmful effect

검색결과 911건 처리시간 0.025초

미나리발효액이 장내 유해세균 및 유익균의 In Vitro 생육 및 효소활성에 미치는 영향 (Effect of Extract of Fermented Dropwort on Intestinal Bacteria and Enzymes In Vitro)

  • 이경애;김무성;조홍범
    • 미생물학회지
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    • 제44권4호
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    • pp.358-361
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    • 2008
  • 미나리(Oenanthe stolonifera) 발효액이 장내 병원성 미생물과 유익균의 생육, 그리고 장내 세균효소에 미치는 영향을 in vitro 에서 조사하였다. 고상 배지 (Agar plate) 에서의 clear zone 형성에 의한 생육저해를 측정한 결과, Vibro, Salmonella 등의 유해 미생물에 대해서 강한 생육저해 효과를 보였으며 Bifidobacterium longum 에 대해서는 생육저해 효과가 크지 않았다. 액체배지에서의 최소저해농도(MIC) 측정에서도 고장배지에서와 같은 경향을 보여 상대적으로 B. longum 에 대한 생육저해가 가장 적었다. 발효 기간에 따른 영향을 보면 발효 기간이 길수록 적은 양으로도 유해한 균들의 생육을 잘 저해할 수 있는 것으로 나타났다. 장내 세균 효소인 ${\beta}$-glucuronidase와 tryptophanase의 활성에 대해 미나리 발효액은 발효하지 않은 액에 비해 저해효과가 컸으며 발효기간이 길수록 저해효과도 증가하였다. 이상의 실험 결과로서 미나리 발효액은 유해세균에 대한 생육저해능이 크고 상대적으로 유익균인 B. longum에 대한 저해는 적어, 음용 시 정장 효과가 있을 것으로 추정된다.

노인의 스트레스가 우울에 미치는 영향 -자아탄력성의 매개효과와 사회활동의 조절효과를 중심으로- (The Effect of the Elderly's Stress on Depression -Focused on Mediating Effect of Resilience and Moderating Effect of Social Activity-)

  • 전영자
    • 한국생활과학회지
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    • 제24권2호
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    • pp.219-236
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    • 2015
  • The purpose of this study is to examine the effect of the elderly's stress on depression, and also to verify the mediating effect of the elderly's resilience and the moderating effect of their social activity between stress and depression. To achieve the purpose of this study, questionnaire survey was conducted. Research subjects of this study were 487 elderly people who were 60 years old and over in Gimhae area. Both the elderly participating in senior welfare center or community center and home care elderly people were included in survey. The study results are as follows: First, there were significant influence of the elderly's stress on depression. Second, the mediating effect of the elderly's resilience between stress and depression was verified. Both the direct effect of stress on depression and indirect effect of stress through resilience on depression were verified. Third, the moderating effect of the elderly's social activity between stress and depression was verified. It was found that the harmful effect of the elderly's stress on depression could be alleviated by participation in social activity. Through the study result, the elderly's resilience which is internal resource, is needed to be strengthened to alleviate depression derived from stress. Also, the elderly's active participation in social activity is needed to be encouraged to prevent the harmful effect of the elderly's stress on depression. Therefore, it is recommended that programs enhancing resilience of the elderly should be developed and the elderly should be supported to participate in social activity more actively.

우리나라 전력부문의 환경유해보조금 개편 효과분석 : 산업용 교차보조금 개편을 중심으로 (Analysis of the Effect of Korea's Environmentally Harmful Subsidy Reform in the Electric Power Sector : Mainly on its Industrial Cross-subsidies Reform)

  • 강만옥;황욱
    • 환경정책연구
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    • 제9권1호
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    • pp.57-81
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    • 2010
  • 고유가 시대인 현실에서 우리나라는 화석연료에 대한 의존도가 높아 저탄소 녹색성장이 가능한 경제사회 구조로의 전환이 시급하다. 현재 화석연료 사용과 관련된 보조금 개편은 환경에 유해한 투입요소에 대한 보조금을 감축 또는 제거하여 경제적 효율성을 제고하고 환경 피해를 완화시켜 사회 전체적으로 편익을 가져올 수 있는 Win-Win 효과가 기대되는 정책방안이다. 특히, 우리나라 전력부문에서 시행되는 보조금 제도 중에서 산업용, 농업용 및 심야전력에 대한 교차보조금의 경우, 전체 전력부문 보조금의 80% 이상을 차지하는 가장 큰 규모인데 본 논문은 전력부문 환경유해보조금 가운데 가장 큰 비중(연간 약 1조 6,583억원)을 차지하는 교차보조금 제도 중에서 산업용 전기의 환경유해보조금 개편 시 기대될 수 있는 파급효과를 가격탄력성 추정을 통해 파악하였다. 가격탄력성 추정에는 ARDL(자기회귀시차분포) 모형을 이용하였고, 기본 데이터는 1990년부터 2007년까지의 분기별 자료를 이용하였다. 본 연구에서 환경유해보조금 제거로 산업용 전력에 대한 연간 에너지 수요변화량은 -12,475,930MWh만큼 사용량이 감소할 것으로 추정되었으며, 이산화탄소 배출량의 경우를 보면 연간 2,644,897톤이 감소하는 것으로 추정되어 보조금 폐지가 이산화탄소 저감에 상당한 기여를 하는 것으로 나타났다. 또한 EU에서 제시한 오염물질 단위당 환경오염비용을 이용하여 배출저감량을 금액으로 환산하면 산업용 전력보조금 제거로 연간 약 1조 1,914억원의 환경개선편익 발생하는 것으로 나타났다. 그리고 이산화탄소의 경우 톤당 25유로를 적용하여 계산하면 산업용 전력보조금 제거로 연간 약 1,062억원의 환경개선편익이 발생하는 것으로 나타났다.

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생체전기임피던스 측정법에 의한 경신강지환16의 비만개선 효과 평가 (Clinical efficacy of Gyeongshingangjeehwan16 according to bioimpedence analysis system)

  • 정양삼;윤기현;최승배;윤미정;신순식
    • 동의신경정신과학회지
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    • 제19권1호
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    • pp.71-81
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    • 2008
  • Objective: Obesity threatens not only the problem of beauty but also health. Furthermore, it could be harmful a chronic disease to increase mortality rate. A purpose of this study is to show a effect of obesity control as developing a herbal medicine, Gyeongshingangjeehwan16 (GGEx16), in order to control obesity that is a harmful factor for healthy. Method : In order to prove the effect of GGEx16, BMI, fat distribution, fat control and fitness score which are closely related with obesity are considered as variables. Each variable is measured, for statistical analysis, using measurement implement of InBody 3.0 which applied a theory of bioimpedence analysis. Result and Conclusion : As a result of statistical analysis for four variables, it was improved that there are the improved effect for obesity because GGEx16 is statistically meaningful better than prior to taking.

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조류기인 유기물질의 제브라피쉬에 대한 뇌파측정기반 독성평가 (Electroencephalography (EEG) based Toxicity Test of Algae Organic Matter on Zebrafish)

  • 오세현;장형준;조윤철
    • 한국물환경학회지
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    • 제39권3호
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    • pp.223-230
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    • 2023
  • Harmful algae blooms have become a serious environmental problem in major river basins in Korea. They are known to produce various algal organic matters (AOMs) including intracellular organic matters (IOMs) and extracellular organic matters (EOMs). Generally AOMs cannot be easily removed by coagulation/flocculation process in conventional drinking water plants. AOMs produced by blue-green algae also include various toxins such as Microcystins, Anatoxin-a, and Saxitoxin known to have harmful effects on living organisms in aquatic environment. In this study, toxic effects of EOMs produced by three different algae species (Microcystis sp., Anabaena sp., and Oscillatoria sp.) on zebrafish were investigated using electroencephalography (EEG) recording method, a technology for recording brain activity. Electroencephalographic changes in zebrafish revealed that a low EOM had a negative effect on zebrafish compared to both Anabaena sp. and Oscillatoria sp. at 30 ppm EOM exposures. This result might be due to Microcystins present in EOMs produced by Microcystis sp. As a result of power spectrum density anallysis, exposure to EOMs produced by Microcystis sp. caused a state of vigilance in zebrafish. This EEG based toxicity test can be used to examine effects of harmful materials at low levels on living organisms in an aquatic system.

경춘선 1급 신설터널에서 열차승객의 이명감 없이 주행 가능한 열차속도에 대한 연구 (Aerodynamic analysis for train operation without the effect of the passenger ear-discomfort in tunnel of new Seoul-Chunchon line)

  • 김동현
    • 한국철도학회:학술대회논문집
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    • 한국철도학회 2000년도 춘계학술대회 논문집
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    • pp.495-502
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    • 2000
  • For the tunnel design of the first class on new Seoul-Chunchon railway, we investigated for train speeds to run through tunnels without ear-discomfort of passenger in cabin by application of numerical analysis. Also we analyzed the effect of the wind speed induced by train in tunnel that is very harmful to the workers on railroad and the effect of the air-pressure fluctuations which get the fatigue to the tunnel lining and the car body.

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남녀 대학생들의 방사선 인식 정도에 관한 비교 연구 (A Comparative Study on the Radiation Awareness of University Students Gender in Chungbuk Area)

  • 장재선;황성희
    • 한국식품영양학회지
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    • 제28권3호
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    • pp.486-492
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    • 2015
  • This study was conducted to provide fundamental data on the awareness of radiation, specifically the differences between general awareness, psychological state and harmful effects. Data was collected from 334 University students in the Chungbuk region through a self-administered questionnaire. According to the results of the reliability and factor analysis, the awareness of radiation was 2.80, with a Cronbach alpha coefficient of 0.815 and KMO of 0.798. Factor analysis extracted three components of the awareness of radiation, which we named general awareness (factor 1), psychological state (factor 2), and harmful effect (factor 3). There were significant differences in the general awareness of natural radiation and radiation-containing foods (p<0.05), whereas no significant differences were found in the general awareness of radiation food supply (p>0.05). Also, the psychological state showed a significant difference in exposure inspection, future exposure, and radiation-containing food (p<0.05), whereas no significant differences were found in the refusal of radiation inspection (p>0.05). The harmful effects showed a significant difference in the rejection of radiation (p<0.05), but no significant differences in the cancer and genetic effects, diseases and physical harmfulness (p>0.05). A significant positive result (p<0.05) was found for the psychological state according to the harmful effects of radiation. Based on this study, detailed and continuous education must be accomplished by increasing the awareness of radiation and the acceptance level, conveying a proper understanding of radiation and assisting subjects with receiving the information they desire through various educational mediums.

활성탄소섬유의 비표면적에 따른 유해가스 흡착 및 전기화학적 감응 특성 (Effect of Specific Surface Area of Activated Carbon Fiber on Harmful Gas Adsorption and Electrochemical Responses)

  • 강진균;정용식;배병철;류지현
    • 접착 및 계면
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    • 제21권2호
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    • pp.51-57
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    • 2020
  • 최근 산업활동을 통해 배출되는 유해 오염물질 제거에 대한 관심이 증가하고 있다. 본 연구에서는 수증기 활성화 법을 이용하여 활성탄소섬유를 제조하고, 이의 유해가스 흡착 및 전기화학적 감응 특성을 분석하였다. 활성탄소섬유의 균일한 기공 구조, 활성 반응 면적 및 반응 위치를 조절하기 위하여, 활성화 온도(750-850 ℃) 및 활성화 시간(30-240 min)을 조절하였고, 다양한 활성화 조건을 통해 제조된 활성탄소섬유의 SO2와 NO 가스 흡착 및 가스 센서를 통한 감응 특성을 분석하였다. 특히, 850 ℃에서 45 min동안 수증기 활성화 반응을 통해 제조된 활성탄소섬유가 가장 높은 비표면적(1,041.9 ㎡/g)과 기공 특성(0.42 ㎤/g)을 보였으며, 우수한 SO2 (1.061 mg/g) 및 NO (1.210 mg/g) 가스 흡착 특성을 보였다.

Purine이 생쥐 미성숙난자의 핵성숙에 미치는 영향 II. 미성숙 난자의 제 1극체 방출과 생존성에 미치는 Purine의 효과 (Effects of Purine on Meiotic Maturation of Mouse Immature Oocytes II. Effects of Purine on Extrusion Rates of 1st pb and Viability of Immature Oocytes)

  • 지희준;황영희;이훈택;정길생
    • 한국가축번식학회지
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    • 제17권2호
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    • pp.85-92
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    • 1993
  • In the previous study, we observed that Purine has a time dependent effect in maintaining the oocytes in meiotic arrest, and human fetal cord serum(HFCS) and human mature follicular fluid(HMFF) reverse the GVBD suppressed by purines. And it was reported that purine has a harmful effect on the development of oocytes or embryos, when they were cultured for a long time, in vitro. Therefore this study was performed to investigate the effects of purine on extrusion rates of 1st pb and viability of oocytes cultured for a long time, in vitro. Immature oocytes(GV stage) were collected from ovaries of 25~28 day old ICR mice at 48 hrs after PMSG injection. Cumulus-enclosed and denuded oocytes collected were assigned randomly to one of several culture conditions. Some of the oocytes were cultured in 4mM hypoxanthine for 24hr, and the extrusion rates of 1st pb and viability of the oocytes were assessed at every 12 hrs. In the viability, the oocytes showed granulation, pigmentation of cytoplasm or lysis of 1st pb extruded were regarded as degenerating oocytes. Also some of the oocytes were cultured in hypoxanthine for 12 hrs then the resulting oocytes were transferred to hypoxanthine-free medium and cultured for 12 hrs to determine whether the inhibitory effect of hypoxanthine on the 1st pb extrusion was reversible. The rest of the oocytes were cultured in medium containing hypoxanthine and adenosine for 18 hrs to compare the 1st pb extrusion be attendant upon hte concentration of HFCS or HMFF supplemented. Hypoxanthine suppressed the extrusion of 1st pb and viability of the oocytes significantly, when they were cultured for more than 12 hrs and the harmful effect of hypoxanthine was showed in denuded oocytes, prominently. The suppressive effect of hypoxanthine was reversed by just removal of the hypoxanthine from the cultrue medium. Also there was no difference in reverse the pb extrusion rate suppressed between HFCS and HMFF. The extrusion rate of 1st pb in medium containing adenosine and hypoxanthine was increased in line with the concentration of HFCS or HMFF supplemented. Hypoxanthine suppressed the extrusion of 1st pb and viability of the oocytes significantly, when they were cultured for more than 12 hrs and the harmful effect of hypoxanthine was showed in denuded oocytes, prominetly. The suppressive effect of hypoxanthine was reversed by just removal of the hypoxanthine fromthe culture medium. Also there was no difference in reverse the pb extrusion rate suppressed between HFCS and HMFF. The extrusion rate of 1st pb in medium containing adenosine and hypoxanthine was increased in line with the concentration of HFCS or HMFF supplemented.

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구례지역 하상퇴적물의 지질집단별 자연배경치에 대한 연구 (The Study of Natural Background of Geologic Units for Stream Sediments in the Gurye Area)

  • 박영석;장우석;김종균
    • 자원환경지질
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    • 제36권4호
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    • pp.275-284
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    • 2003
  • 구례지역의 1차 수계를 대상으로 하상퇴적물을 채취하여 지질집단별 주성분 및 미량성분원소의 자연배경치를 설정하고자 하였다. 하상퇴적물은 구례지형도에서 오염의 우려가 없고 단일지질로 구성된 집수분지를 대표할 수 있는 시료를 1999년 4월과 5월에 걸쳐 채취하였고 화학분석을 실시하였다 유해원소들의 부화정도를 알아보기 위해 tolerable level윽 이용하여 살펴본 결과 일부 지역에서 Ni과 Cr의 함량이 tolerable love의 허용한계치를 초과하는 것으로 나타나는데, 이는 이들 지역의 기반암인 변성암류의 영향으로 인한 것으로 판단된다. 유해금속원소의 종합적인 부화양상을 규명하기 위하여 tolerable level을 이용하여 부화지수를 산출한 격과, 화강편마암지역은 0.39, 반상변정질화강편 마암지역은 0.32, 흑운모편마암지역은 0.42, 혼성편마암지역은 0.41, 응회암지역은 0.30, 안산암지역은 0.46, 역암지역은 0.42, 화강암지역은 0.26으로 매우 낮은 부화지수를 보여주고 있는 것으로 보아 연구지역의 자연배경치는 유해금속원소의 오염에 노출되지 않은 것으로 판단된다.