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Effect of Extract of Fermented Dropwort on Intestinal Bacteria and Enzymes In Vitro  

Lee, Kyung-Ae (Institute of Natural Sciences, Yong In University)
Kim, Moo-Sung (R&D Center, Macrocare Tech. Ltd.)
Cho, Hong-Bum (Department of Biological Engineering, Seokyeong University)
Publication Information
Korean Journal of Microbiology / v.44, no.4, 2008 , pp. 358-361 More about this Journal
Abstract
Effect of extract of fermented dropwort (Oenanthe stolonifera) on growth of intestinal harmful/useful bacteria and enzyme activity were investigated in vitro. The extract showed strong inhibition on harmful microbes including Vibrio and Salmonella, but mild inhibition on Bifidobacterium longum in both agar plate and liquid cultivation. Minimum inhibitory concentration (MIC) value of B. longum was the highest among tested microbes. Inhibition effect of fermented extract on harmful microbes increased according to fermentation period. Extract of fermented dropwort showed inhibitory effects on activity of microbial ${\beta}$-glucuronidase and tryptophanase. The inhibitory effects were also proportional to fermentation period. As consequence, it is assumed that the uptake of fermented dropwort might be useful for human intestinal health.
Keywords
${\beta}$-glucuronidase; fermentation; intestinal bacteria; Oenanthe stolonifera; tryptophanase;
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Times Cited By KSCI : 2  (Citation Analysis)
Times Cited By SCOPUS : 1
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1 이선화, 신현경. 1995. 쑥의 분획추출물이 주요 장내세균의 in vivo 생육에 미치는 영향. 한국영양학회지 28, 1065-1072
2 Kinoshita, N. and H.V. Gelboin. 1978. beta-Glucuronidase catalyzed hydrolysis of benzo(a)pyrene-3-glucuronide and binding to DNA. Science 199, 307-309   DOI   ScienceOn
3 Lee, H.C., A.M. Jenner, C.S. Low, and Y.K. Lee. 2006. Effect of tea phenolics and their aromatic fecal bacterial metabolites on intestinal microbiota. Res. Microbiol. 157, 876-884   DOI   ScienceOn
4 Thornton, J.R. 1981. High colonic pH promotes colorectal cancer. Lancet 16, 1081-1083
5 이종호, 박종철, 유영법. 1993. 미나리의 Steroid 및 Flavonoid. 생약학회지 24, 244-246
6 Seo, W.H. and H.H. Baek. 2005. Identification of characteristic aroma-active compounds from water dropwort (Oenanthe javanica DC.). J. Agric. Food Chem. 53, 6766-6770   DOI   ScienceOn
7 Fishman, W.H. 1974. Glucuronidase, p. 930-932. In H.U. Bergmeyer, 2nd ed., vol. 2. Methods of Enzymatic Analysis. Academic Press, N.Y., USA
8 Park, K.Y., K.I. Lee, and S.H. Rhee. 1992. Inhibitory effect of green-yellow vegetables on mutagenicity in Salmonella assay system and on growth of AZ-521 human gastric cancer cells. J. Korean Soc. Food Nutr. 21, 149-153   과학기술학회마을
9 최성숙, 하남주. 1999. 식이에 따른 장내세균의 효소활성 및 장내세균총의 비교. 한국미생물학지35, 128-132
10 Lee, K.I., K.Y. Park, and S.H. Rhee. 1992. Antimutagenic effect of green-yellow vegetables toward aflatoxin B1 and 4-nitroqinoline- 1-oxide. J. Korean Soc. Food Nutr. 21, 143-148
11 Reddy, B.S., J.H. Weisburger, and E.L. Wynder. 1974. Fecal bacterial beta-glucuronidase: control by diet. Science 183, 416-417   DOI   ScienceOn
12 Cummings, J.H. and G.T. Macfarlane. 1991. The control and consequences of bacterial fermentation in the human colon. J. Appl. Bacteriol. 70, 443-459   DOI   PUBMED
13 Kim, Y.C., E.Y. Jung, H.J. Kim, and S.M. Kang. 1999. Improvement of kimchi fermentation by using acid-tolerent mutant of Leuconostoc mesenteroides and aromatic yeast Saccharomyces fermentati as starters. J. Microbiol. Biotechnol. 9, 22-31
14 Mitsuoka, T. 1992. Intestinal flora and aging. Nutr. Rev. 50, 438-446   DOI   PUBMED   ScienceOn
15 Park, J.C., Y.B. Yu, J.H. Lee, and N.J. Kim. 1994. Studies on the chemical components and biological activator of edible plants in Korea (VI)-antiinflamantory and anlages effects of Cedrela sinensis, Oenanithe javanica and Artemisia princeps var. orientalis. J. Korean Soc. Food. Nutr. 23, 116-119   과학기술학회마을
16 Okubo, T., N. Ishihara, A. Oura, M. Serit, M. Kim, T. Yamamoto, and T. Mitsuoka. 1992. In vivo effects of tea polyphenol intake on human intestinal microflora and metabolism. Biosci. Biotech. Biochem. 56, 588-591   DOI
17 Chung, K.T., G.E. Fulk, and M.W. Slein. 1975. Tryptophanase of fecal flora as a possible factor in the etiology of colon cancer. J. Natl. Cancer Inst. 54, 1073-1078   DOI   PUBMED