• Korean Journal of Clinical Laboratory Science
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• v.44 no.3
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• pp.103-111
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• 2012

Low-Density Lipoprotein cholesterol (LDLC) is the most important marker for the treatment of hyperlipidemia in NCEP-ATP III(National Cholesterol Education Program-Adult Treatment Panel III) guideline. Therefore, LDL cholesterol is pathologically meaningful, accurate measurement should be a top priority. Currently, LDLC is directly measured in most cases, but, the estimate is still used in mass health examination or screening test. This study is about the comparison of LDL-Cholesterol direct measurement with the estimate using various formula (Friedewald: [LDL-F=TC-HDL-TG/5], Nakajima: [LDL-N=TC-HDL-TG/4], Hattori: [LDL-H =0.94TC-0.94HDL-0.19TG], Puavilai: [LDL-P=TC-HDL-TG/6], Carvalho: [LDL-C=3(TC-HDL)/4]) for calculating more accurate value. We analyzed total cholesterol (TC), try-glyceride (TG), high-density lipoprotein cholesterol (HDLC), and LDLC levels of 210 subjects between June and November in 2011. Until now, the Friedewald formula is the most commonly used estimate for the LDLC. When Friedewald formula was applied, the correlation coefficient (r) was 0.940, showing high correlation. But, the result of the direct method was significantly different, compared with those of the Friedewald formula in triglyceride levels ${\geq}400mg/dL$(p<0.05). There was the highest correlation when we used LDL-P formula(r=0.947) in triglyceride levels <400 mg/dl. Also there was the lowest mean difference regardless of triglyceride level. Therefore, the study showed that TG/6 is more precise means of calculation than TG/5. On the other hand, the calculation of LDL-Cholesterol was underestimated, compared with direct measurement. It is necessary to have more data and modified Friedewald formula should be used for the accurate calculation.

• Asian Pacific Journal of Cancer Prevention
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• v.14 no.5
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• pp.2753-2758
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• 2013

Various studies examining the relationship between Ezrin overexpression and response to chemotherapy and clinical outcome in patients with osteosarcoma have yielded inconclusive results. We accordingly conducted a meta-analysis of 7 studies (n = 318 patients) that evaluated the correlation between Ezrin and histologic response to chemotherapy and clinical prognosis (death). Data were synthesized in receiver operating characteristic curves and with fixed-effects and random-effects likelihood ratios and risk ratios. Quantitative synthesis showed that Ezrin is not a prognostic factor for the response to chemotherapy. The positive likelihood ratio was 0.538 (95% confidence interval [95% CI], 0.296- 0.979; random-effects calculation), and the negative likelihood ratio was 2.151 (95% CI, 0.905- 5.114; random-effects calculations). There was some between-study heterogeneity, but no study showed strong discriminating ability. Conversely, Ezrin positive status tended to be associated with a lower 2-year survival (risk ratio, 2.45; 95% CI, 1.26-4.76; random-effects calculation) with some between-study heterogeneity that disappeared when only studies that employed immunohistochemistry were considered (risk ratio, 2.97; 95% CI, 2.01- 4.40; fixed-effects calculation). To conclude, Ezrin is not associated with the histologic response to chemotherapy in patients with osteosarcoma, whereas Ezrin positivity was associated with a lower 2-year survival rate regarding risk of death at 2 years. Expression change of Ezrin is an independent prognostic factor in patients with osteosarcoma.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.40 no.4
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• pp.137-146
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• 2017

For the competitive business environment under purchase dependence, this paper proposes a new approximate calculation of order fill rate which is a probability of satisfying a customer order immediately using the existing inventory. Purchase dependence is different to demand dependence. Purchase dependence treats the purchase behavior of customers, while demand dependence considers demand correlation between items, between regions, or over time. Purchase dependence can be observed in such areas as marketing, manufacturing systems, and distribution systems. Traditional computational methods have a difficulty of the curse of dimensionality for the large cases, when deriving the stationary joint distribution which is utilized to calculate the order fill rate. In order to escape the curse of dimensionality and protect the solution from diverging for the large cases, we develop a greedy iterative search algorithm based on the Gauss-Seidel method. We show that the greedy iterative search algorithm is a dependable algorithm to derive the stationary joint distribution of on-hand inventories in the retailer system by conducting a comparison analysis of a greedy iterative search algorithm with the simulation. In addition, we present some managerial insights such as : (1) The upper bound of order fill rate can be calculated by the one-item pure system, while the lower bound can be provided by the pure system that consists of all items; (2) As the degree of purchase dependence declines while other conditions remain same, it is observed that the difference between the lower and upper bounds reduces, the order fill rate increases, and the order fill rate gets closer to the upper bound.

• Journal of Ocean Engineering and Technology
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• v.19 no.5 s.66
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• pp.1-15
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• 2005

The motion behaviors including hydrodynamic interaction and mechanical coupling effects on multiple-body floating platforms are simulated by using a time domain hull/mooring/riser coupled dynamics analysis program. The objective of this study is to evaluate off-diagonal hydrodynamic interaction effects and mechanical coupling effects on tandem moored FPSO and shuttle taker motions. In the multiple-body floating platforms interaction, hydrodynamic coupling effects with waves and mechanical coupling effects through the connectors should be considered. Thus, in this study, the multiple-body platform motions are calculated by Combined Matrix Method (CMM) as well as Separated Matrix Method (SMM). The advantage of the combined matrix method is that it can include all the 6Nx6N full hydrodynamic and mechanical interaction effects among N bodies. Whereas, due to the larger matrix size, the calculation time of Combined Matrix Method (CMM) is longer than the Separated Matrix Method (SMM). On the other hand, Separated Matrix Method (SMM) cannot include the off-diagonal 6x6 hydrodynamic interaction coefficients although it can fully include mechanical interactions among N bodies. To evaluate hydrodynamic interaction and mechanical coupling effects, tandem moored FPSO and shuttle tanker is simulated by Combined Matrix Method (CMM) and Separated Matrix Method (SMM). The calculation results give a good agreement between Combined Matrix Method (CMM) and Separated Matrix Method (SMM). The results show that the Separated Matrix Method (SMM) is more efficient for tandem moored FPSO and shuttle tanker. In the numerical calculation, the hydrodynamic coefficients are calculated from a 3D diffraction/radiation panel program WAMIT, and wind and current forces are generated by using the respective coefficients given in the OCIMF data sheet.

• Journal of the Korean Society of Manufacturing Technology Engineers
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• v.26 no.2
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• pp.223-229
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• 2017

Recently, robotic bin-picking tasks have drawn considerable attention, because flexibility is required in robotic assembly tasks. Generally, stereo camera systems have been used widely for robotic bin-picking, but these have two limitations: First, computational burden for solving correspondence problem on stereo images increases calculation time. Second, errors in image processing and camera calibration reduce accuracy. Moreover, the errors in robot kinematic parameters directly affect robot gripping. In this paper, we propose a method of correcting the bin-picking error by using trinocular vision system which consists of two stereo cameras andone hand-eye camera. First, the two stereo cameras, with wide viewing angle, measure object's pose roughly. Then, the 3rd hand-eye camera approaches the object, and corrects the previous measurement of the stereo camera system. Experimental results show usefulness of the proposed method.

• Journal of the Korean Geotechnical Society
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• v.27 no.8
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• pp.63-71
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• 2011

In case of applying BIM method to the civil engineering of irregularly shaped structure, BIM method is recognized to have relatively high construction productivity. In this paper, we developed quantity calculation algorithms applying BIM method to NATM tunnel construction method and implemented BIM based 3D-BIM Modeling Quantity Calculation. The results showed that BIM-based method has high reliabilty in structure work in which errors occurred only in the range between 0.00% and -1.45%. On the other hand, BIM method applied to earth work showed great error range of -19.78% to 35.30%. So the benefit and applicability of BIM method in civil engineering were confirmed. In addition, routine method for the quantity of earth work has negligible error as in the case of structure work. But, rock type's quantity calculation showed significant errors so that the reliability of 2D-based volume calculation is problematic. It may thus be concluded that 3D-BIM is more reliable than the routine method in estimating the quantity of earth work. Considering the reliability and merits in the stage of its design, construction and maintenance levels, the application of BIM to civil engineering works is recommended.

• Journal of Korea Game Society
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• v.13 no.5
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• pp.43-54
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• 2013

With the consistent development of the 3D application technique, visuals are available at more realistic quality and are utilized in many applications like game. In particular, interacting with 3D objects in virtual environments, 3D graphics have led to a substantial development in the augmented reality. This study proposes a 3D user interface to control objects in 3D space through virtual two-view method using only one camera. To do so, homography matrix including transformation information between arbitrary two positions of camera is calculated and 3D coordinates are reconstructed by employing the 2D hand coordinates derived from the single camera, homography matrix and projection matrix of camera. This method will result in more accurate and quick 3D information. This approach may be advantageous with respect to the reduced amount of calculation needed for using one camera rather than two and may be effective at the same time for real-time processes while it is economically efficient.

• Structural Engineering and Mechanics
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• v.60 no.3
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• pp.365-386
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• 2016

This paper describes a systematic numerical investigation into the nonlinear elastic behavior of conical shells, with various types of initial imperfections, subject to a uniformly distributed axial compression. Three different patterns of imperfections, including first axisymmetric linear bifurcation mode, first non-axisymmetric linear bifurcation mode, and weld depression are studied using geometrically nonlinear finite element analysis. Effects of each imperfection shape and tapering angle on imperfection sensitivity curves are investigated and the lower bound curve is determined. Finally, an empirical lower bound relation is proposed for hand calculation in the buckling design of conical shells.

• Journal of Advanced Marine Engineering and Technology
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• v.30 no.1
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• pp.73-80
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• 2006

In order to compute the radiated sound from a vibrating structure, the Rayleigh's integral equation has to be derived from the Helmholtz equation using Green's function. Generally, the surface velocity in the Rayleigh's integral equation uses the root mean square(rms) velocity. The calculation value is too large, because it's not considered cancelation. On the other hand. using the complex velocity, the sound pressure is calculated too small, because it considers that sound is perfectly canceled out. Therefore, this thesis proposes a correction factor(CF) which considers vibration modes and the method by which to calculate the radiating sound pressure. The theoretical results are compared with the experimental values, and the proposed method can be verified with confluence.

• Journal of the Korean Operations Research and Management Science Society
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• v.20 no.1
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• pp.1-10
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• 1995

The purpose of this paper is to develop a method of the sensitivity analysis that can be applied to a non-tree solution of the minimum cost flow problem. First, we introduce two types of sensitivity analysis. A sensitivity analysis of Type 1a is the well known method applicable to a tree solution. However this method can not be applied to a non-tree solution. So we propose a sensitivity analysis of Type 2 that keeps solutions of upper bounds at upper bounds, those of lower bounds at lower bounds, and those of intermediate values at intermediate values. For the cost coefficient we present a method that the sensitivity analysis of Type 2 is solved by finding the shortest path. Besides we also show that the results of Type 2 and Type 1 are the same in a spanning tree solution. For the right-hand side constant or the capacity, the sensitivity analysis of Type 2 is solved by a simple calculation using arcs with intermediate values.