• Journal of Korean Society of Rural Planning
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• v.10 no.2 s.23
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• pp.1-6
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• 2004

This study tried to construct a direction in regional planning concerning the structural relationship between the ratio of aged population and the industrial characteristics. We investigated this structural relationship incorporating the aged population index and the number of classified companies. We applied diverse statistical analyses to understand the relationship. We classified the number of companies to reflect regional industrial characteristics using the principal component analysis. We applied a multiple regression model to understand the relationship between these two indices. The aged population index represents the degree of being old divided by the ratio of juvenile population and aged population. We found that such industries as manufacturing, service, and conveyance increase the ratio of juvenile population. However, industries such as tourism, waterworks, forestry, agriculture and etc. have a positive effect on the aged population index. In addition to these findings, we believe that the efficacy of this study is the possibility that can be used as the basic data when central or local autonomous entities need to adopt rural development planning.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.9
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• pp.4403-4407
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• 2012

Background: Glutathione-S-Transferase T1 (GSTT1) gene has been shown to be involved in the development of esophageal cancer. However, the results have been inconsistent. In this study, the authors performed a meta-analysis to clarify the association between GSTT1 polymorphism and esophageal cancer risk among Chinese Han population. Methods: Published literature from PubMed, the China National Knowledge Infrastructure and Wanfang Data were searched. Pooled odds ratio (OR) and 95% confidence interval (95%CI) was calculated using a fixed- or random-effects model. Results: Eleven studies with a total of 2779 individuals were included in the meta-analysis. The results showed that GSTT1 null genotype was significantly associated with esophageal cancer risk in Chinese (OR = 1.31, 95%CI 1.12 to 1.53, p = 0.001). Further sensitivity analyses confirmed the significant association. The cumulative meta-analysis showed a trend of an obvious association between GSTT1 null genotype and esophageal cancer risk as information accumulated by year. Conclusions: This meta-analysis suggests a significant association of GSTT1 null genotype with esophageal cancer risk in the Chinese Han population.

• Journal of the Korean Professional Engineers Association
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• v.15 no.1
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• pp.46-50
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• 1982

Following rapid industrial development and urbanization in Korea, there is a need for the Government to implement effective control of pollution and to undertake specific schemes in areas where pollution of the environment is severe. In response to this need, Government of Korea prepare Han River Basin Environmental Master Plan Project for water, air, solid waste to cover environmental protection of the Han River Basin. The Project area is approximately 27,000 sq. Km extending over Seoul, Kyunggi, Kwangwon, Chungbuk Province. The total population of Master Plan Project area is approximately 11.6 million, or one-third of the total population of Korea. There are about 8,000 industries, including those located in 16 industrial complexes, in the project area. The scope of work and terms of reference are the following: (1) A Summary of existing land use and forecasts for changes in land use by the year 2,000. (2) Emission inventories for air, waste water, and solid wastes. (3) Forecasts of future population growth patterns and pollution loadings. (4) Identification of specific projects needs to reduce pollution levels and satisfy the environmental quality standards. (5) A Program of enforcement to include (i) self monitoring, and (ii) governmental inspections and surveillance. (6) A program for quality improvement and quality assurance of environmental measurements. (7) Reports summarizing all data collected analyzed during the study. (8) Conceptual design and feasibility studies, including cost estimates, for needed pollution control projects. (9) A financial plan for future detailed design and construction of public facilities, for financial incentives to industry, and for user charges for industrial use of public treatment of disposal works.

• The Journal of the Korean dental association
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• v.54 no.6
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• pp.468-474
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• 2016

Korean government enacted the 1st Basic Plan for Low Fertility and Population Ageing in 2005 due to the long-lasting ultra-low birth rate. Based on the Act, Korean government set up a step-by-step strategic goal and establish a basic plan, every five years, to achieve the sustainable development of society corresponding to low fertility and aging society. Over the past decade, the 1st Basic Plan for Low Fertility and Population Ageing (2006-2010) and the 2nd Basic Plan for Low Fertility and Population Ageing (2011-2015) was executed. This year, based on the achievements and limitations of the 1st and 2nd Basic Plan, the 3rd Basic Plan for Low Fertility and Population Ageing begins. In this manuscript, I discuss the background of the 3rd Basic Plan and its significance in oral health area.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.19
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• pp.8503-8508
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• 2014

Background: After the WHO recommended HPV vaccination of the general population in 2009, government support of HPV vaccination programs was increased in many countries. However, this policy was not implemented in Korea due to perceived low cost-effectiveness. Thus, the aim of this study was to analyze the cost-utility of HPV vaccination programs targeted to high risk populations as compared to vaccination programs for the general population. Materials and Methods: Each study population was set to 100,000 people in a simulation study to determine the incremental cost-utility ratio (ICUR), then standard prevalence rates, cost, vaccination rates, vaccine efficacy, and the Quality-Adjusted Life-Years (QALYs) were applied to the analysis. In addition, sensitivity analysis was performed by assuming discounted vaccination cost. Results: In the socially vulnerable population, QALYs gained through HPV vaccination were higher than that of the general population (General population: 1,019, Socially vulnerable population: 5,582). The results of ICUR showed that the cost of HPV vaccination was higher for the general population than the socially vulnerable population. (General population: 52,279,255 KRW, Socially vulnerable population: 9,547,347 KRW). Compared with 24 million KRW/QALYs as the social threshold, vaccination of the general population was not cost-effective. In contrast, vaccination of the socially vulnerable population was strongly cost-effective. Conclusions: The results suggest the importance and necessity of government support of HPV vaccination programs targeted to socially vulnerable populations because a targeted approach is much more cost-effective. The implementation of government support for such vaccination programs is a critical strategy for decreasing the burden of HPV infection in Korea.

• Korean Journal of Ichthyology
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• v.24 no.4
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• pp.278-286
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• 2012

This study was examined for information of management of bluegill, Lepomis macrochirus which is disturbance species of underwater ecosystem in Korea. Research of bluegill population was investigated spring-summer and autumn periods in the Han river system from 2009 to 2012. Bluegill inhabited mostly lakes, and restrictedly lived at still area in downstream. The range of relative abundance were 0.2~18.2% in individual number and 0.2~40.0% in biomass and it was subdominant or superiority species for the most part of the lakes. Population structure were analyzed r-strategy in Lake Soyang and Paldang and K-strategy in Lake Uiam and Cheongpyeong. But Lake Chungju was estimated transition period from K-strategy to r-strategy. Condition factor and body weight-total length relations were presented favorable condition. For the nesting, bluegill was formatted the group. And the water depth and the distance from shore were mean 56.3 cm and 191.9 cm respectively in nesting ground. Diameter and depth of nests were mean 42.4 cm and 9.7 cm respectively. These results are available for research of population dynamics and reproductive ecology of bluegill.

• The Korean Journal of Applied Statistics
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• v.33 no.2
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• pp.185-201
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• 2020

Scenario population projection reflects the high probability of future realization and ease of statistical interpretation. Statistics Korea (2019) also presents the results of 30 combinations, including special scenarios, as official statistics. However, deterministic population projections provide limited information about future uncertainties with several limitations that are not probabilistic. The deterministic population projections are scenario-based estimates and show a perfect autocorrelation of three factors (birth, death, movement) of population variation over time. Therefore, international organizations UN, the Max Planck Population Research Institute (MPIDR) of Germany and the Vienna Population Research Institute (VID) of Austria have suggested stochastic based population estimates. In addition, some National Statistics Offices have also adopted this method to provide information along with the scenario results. This paper calculates the demographics of Korea based on a probabilistic or stochastic basis and then draws the pros and cons and show implications of the scenario (deterministic) population projections.

• Translational and Clinical Pharmacology
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• v.26 no.3
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• pp.143-143
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• 2018

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.21
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• pp.9177-9183
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• 2014

Polymorphisms of inflammation-related genes have been found to be associated with non-Hodgkin lymphoma (NHL) or some of its subtypes, but only a few relevant data have been reported in China. In this study, the Snapshot method was used to assess genetic variation; a total of 14 single nucleotide polymorphisms (SNPs) for 6 inflammatory factors in 157 NHL cases (64 Uygur ethnic subjects, 93 Han Chinese) and 435 controls (231 Uygur and 204 Han Chinese) were studied from the Xinjiang province of China. Haplotype distribution was estimated using PHASE 2.3 software. Statistical differences in the genotype and haplotype frequencies between case and control groups were also considered and estimated. For the Han population, the geneotype distributions for TNF-${\alpha}rs1800629$, TNF-${\alpha}rs1800630$, IL-6 rs1800795, IL-6 rs1800797, NF-KB1 rs1585215 and TLR-4 rs4986790 showed significant differences between the case and control groups (p<0.05). The TNF-${\alpha}$ gene frequencies of ACG and CCA haplotypes in the cases were higher than in the controls (OR=2.45, 95% CI: 1.55-3.89, p=0.0002, OR=2.53, 95% CI: 1.10-5.80, p=0.029, respectively), and the same findings were detected for TNF-${\beta}$ gene CA haplotype (OR=1.87, 95% CI: 1.21-2.90, p=0.0054). However, for the Uygur population, no such significant differences were detected within the gene-type distribution of the 14 SNPs. The TNF-${\alpha}$ gene frequency of the CCA haplotype between the two groups (OR=1.98, 95% CI: 1.11-3.51, p=0.021) revealed a statistically significant difference. Our results showed that polymorphic variations of inflammation-related genes could be important to the NHL etiology of the Han population, and that these may only have limited influence on the Uygur population.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.13
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• pp.5207-5214
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• 2014

Background: To study the relationship of susceptibility to lung cancer with the gene polymorphisms of CYP1A1, GSTM1, GSTM3, GSTT1, GSTP1 and smoking status in Han and Mongolian populations of Inner Mongolia, an autonomous region of China. Materials and Methods: PCR-RFLP, allele-specific and multiplex PCR were employed to identify the genotypes of CYP1A1, GSTM1, GSTM3, GSTT1 and GSTP1 in a case-control study of 322 lung cancer patients diagnosed by bronchoscopy and 456 controls free of malignancy. Results: There is a significant difference in genotypic frequency of GSTT1 of healthy Mongolian and Han subjects. A statistically prominent association was found between CYP1A1 Msp1 (vt/vt) (OR=4.055, 95%CI:2.107-7.578, p=0.000), GSTM1 (-) (OR=2.290, 95%CI:1.467-3.573, p=0.000) and lung cancer in Mongolians. Similarly, in the Han population, CYP1A1 Msp1 (vt/vt) (OR=3.194, 95%CI:1.893-5.390, p=0.000) and GSTM1 (-) (OR=1.884, 95%CI:1.284-2.762, p=0.001) carriers also had an elevated risk of lung cancer. The smokers were more susceptible to lung cancer 2.144 fold and 1.631 fold than non-smokers in Mongolian and Han populations, respectively. The smokers who carried with CYP1A1 Msp1 (wt/vt+vt/vt), exon7 (Val/Val+Ile /Val), GSTM1 (-), GSTM3 (AB+BB), and GSTT1 (-) respectively were found all to have a high risk of lung cancer. Conclusions: CYP1A1 Msp1 (vt/vt) and GSTM1 (-) are risk factors of lung cancer in Han and Mongolian population in the Inner Mongolia region. The smokers with CYP1A1 Msp1 (wt/vt+vt/vt), CYP1A1 exon7 (Val/Val+Ile /Val), GSTM1 (-), GSTM3 (AB+BB), and GSTT1 (-) genotypes, respectively, are at elevated risk of lung cancer.