• Title/Summary/Keyword: Half-rate

Search Result 1,805, Processing Time 0.026 seconds

The Effects of Panax ginseng and P. quinquefolium on Hemodynamics and Body Temperature in Healthy Young Men (III)

  • Lee, Jee-Hwan;Cho, Jung-Ah;Ki, Chan-Young;Son, Yeon-Kyoung;Park, Jeong-Hill;Park, Man-Ki;Han, Yong-Nam
    • Proceedings of the Korean Society of Applied Pharmacology
    • /
    • 2003.11a
    • /
    • pp.108-108
    • /
    • 2003
  • The current study was performed to observe the effects of Panax ginseng (PG) and P. quinquefolia (PQ) on hemodynamics such as blood flow rate (BF), blood flow velocity (BV), heart rate (HR), systolic blood pressure (SBP) and diastolic blood pressure (DBP, and body temperature (BT) in healthy young men. After testing equality of variance, Student's t-test using PROC TTEST was examined to. prove statistical differences between control and ginseng conditions at each time point. It was found that the BF data were fluctuated by personal deviation. In order to minimize the deviation, the results obtained for 6 hrs were reconstituted after dividing them into two periods of the first half from 1 to 3 hrs and of the latter half from 3.5 to 6 hrs. And then the reconstitution data and dose-response curves were obtained. Blood flow such as BF and BV shows significant increases both two periods in the dose of PG 2.25 and PG 9.0, whereas significant decrease in the dose of PG 4.5. However, in the PQ groups, the middle dose PQ 4.5 shows the highest significant increase among the three doses. Except for PG 2.25 in HR, other doses show significant decreases both in the first half and latter half. SBP of PQ 9.0 shows only a significant decrease in the first half; on the other hand, in the latter half, PG 4.5, PG 9.0 and PQ 9.0 significantly increase SBP. In addition, DBP of PG 2.25 and PG 4.5 show significant increase in the both periods. In the BT, PQ groups show gradual decrease from PQ 2.25 to PQ 9.0; however, PG groups show differently. PG 4.5 shows significant decrease, but PG 9.0 shows a increase without statistical meanings. In summary, PG is more effective in respect to keeping homeostasis of hemodynamics.

  • PDF

Biopharmaceutical studies on copper(II) chelates of sulfanilamide derivatives (Sulfanilamide유도체의 동(II)착화합물에 대한 생물약제학적 연구)

  • 김재백
    • YAKHAK HOEJI
    • /
    • v.15 no.2
    • /
    • pp.41-52
    • /
    • 1971
  • Cu(II) chelates of several sulfanilamide derivatives (Sulfa-Cu) were prepared and their effects on solubility, absorptivity in intestinal lumen, biding tendency with serum protein and erythrocytes, concentration in rabbit blood, and acetylation rate were studied in comparison with their free ligand forms. For solubility concerned, the partition coefficients of Sulfa-Cu are decreased as following order: Sulfadimethoxine Copper chelate (SDM-Cu), Sulfamethoxypyridazine Copper chelate (SD-Cu), Sulfamerazine Copper chelate (SM-Cu), Sulfaisoxazole Copper chelate (SIX-Cu). The partition coefficients of SDM-Cu and ST-Cu were much greater than those of ligands. this phenomenone acounts for the rapid absorption of SDM-Cu and ST-Cu in the rat small intestine (in situ). The Sulfa-Cu were absorbed at the intestinal lumen of a rat in the rate of first order and there was no difference between long acting sulfa drugs and their Cu0chelates in biological half lives. In binding experiments, sulfa-Cu binded with serum protein in lower ratio than their ligands except SIX-Cu. On other hand, acetylation rates of sulfa-Cu were higher than those of free sulfa drugs and the acetylation rate were higher than those of free sulfa drugs and powder. In a experiment on Sulfa-Cu concentration in rabbit blood, the half lives of SD-Cu, SIX-cu, ST-Cu, and SM-Cu were longer than those of their ligands. Above all, the half life of SD-Cu appeared to be approximately 3.5 times logner than that of corresponding ligand, SD. When absorption of sulfa drugs or sulfa-Cu at the small intestinal lumen of a rat and the concentration in rabbit blood after absorption were compared, it was found that there was not always conrrelated.

  • PDF

Assessing the long-term durability and degradation of rocks under freezing-thawing cycles

  • Seyed Zanyar Seyed Mousavi;Mohammad Rezaei
    • Geomechanics and Engineering
    • /
    • v.34 no.1
    • /
    • pp.51-67
    • /
    • 2023
  • In this research, the degradation rate of physical properties of the Angouran pit bedrock (calc-schist) is first investigated under the specific numbers of freeze-thaw (F-T) cycles. Then, the durability of calc-schist specimens against the F-T cycle number (N) is examined considering the mechanical parameters, and using the decay function and half-time techniques. For this purpose, point load strength (IS(50)), second durability index (Id2), Brazilian tensile strength (BTS), and compressive (VP) and shear (VS) wave velocities of calc-schist specimens are measured after 0, 7, 15, 40, and 75 N. For comparing the degradation rate of mechanical properties of available rock types on the Angouran mine walls, these tests are also carried out on the limestone and amphibolite schist specimens beside the calc-schist. According to test results, the exponential regression models are developed between the mechanical parameters of rock specimen's and N variable. Also, the long-term durability of each rock type versus N is studied using the decay function and half-time techniques. Results indicated that the degradation rate differs for the above rock types in which amphibolite schist and calc-schist specimens have the highest and least resistance against the N, respectively. The obtained results from this study can play a key role in the optimal design of the mine's final walls.

A 5.4Gb/s Clock and Data Recovery Circuit for Graphic DRAM Interface (그래픽 DRAM 인터페이스용 5.4Gb/s 클럭 및 데이터 복원회로)

  • Kim, Young-Ran;Kim, Kyung-Ae;Lee, Seung-Jun;Park, Sung-Min
    • Journal of the Institute of Electronics Engineers of Korea SD
    • /
    • v.44 no.2
    • /
    • pp.19-24
    • /
    • 2007
  • With recent advancement of high-speed, multi-gigabit data transmission capabilities, serial links have been more widely adopted in industry than parallel links. Since the parallel link design forces its transmitter to transmit both the data and the clock to the receiver at the same time, it leads to hardware's intricacy during high-speed data transmission, large power consumption, and high cost. Meanwhile, the serial links allows the transmitter to transmit data only with no synchronized clock information. For the purpose, clock and data recovery circuit becomes a very crucial key block. In this paper, a 5.4Gbps half-rate bang-bang CDR is designed for the applications of high-speed graphic DRAM interface. The CDR consists of a half-rate bang-bang phase detector, a current-mirror charge-pump, a 2nd-order loop filter, and a 4-stage differential ring-type VCO. The PD automatically retimes and demultiplexes the data, generating two 2.7Gb/s sequences. The proposed circuit is realized in 66㎚ CMOS process. With input pseudo-random bit sequences (PRBS) of $2^{13}-1$, the post-layout simulations show 10psRMS clock jitter and $40ps_{p-p}$ retimed data jitter characteristics, and also the power dissipation of 80mW from a single 1.8V supply.

Prediction of Continuous Reactors Performance Based on Batch Reactor Deactivation Kinetics Data of Immobilized Lipase

  • Murty, V.Ramachandra;Bhat, Jayadev;Muniswaran, P.K.A.
    • Biotechnology and Bioprocess Engineering:BBE
    • /
    • v.7 no.4
    • /
    • pp.225-230
    • /
    • 2002
  • Experiments on deactivation kinetics of immobilized lipase enzyme from Candida cyl-indracea were performed in stirred bath reactor using rice bran oil as the substrate and temperature as the deactivation parameter. The data were fitted In first order deactivation model. The effect of temperature on deactivation rate was represented by Arrhenius equation. Theoretical equations were developed based on pseudo-steady state approximation and Michaelis -Menten rate expression to predict the time course of conversion due to enzyme deactivation and apparent half-life of the immobilized enzyme activity in PFR and CSTH under constant feed rate polity for no diffusion limitation and diffusion limitation of first order. Stability of enzyme in these continuous reactors was predicted and factors affecting the stability were analyzed.

An Experimental Study on the Reinforcement Corrosion in Concrete Using Granulated Blast Furnace Slag (고로슬래그 미분말을 사용한 콘크리트 내의 철근부식에 관한 실험적 연구)

  • 이동혁;김은겸;김영웅;김영철
    • Proceedings of the Korea Concrete Institute Conference
    • /
    • 2002.05a
    • /
    • pp.761-766
    • /
    • 2002
  • This paper was peformed to verify the effect that granulated blast furnace slag gets in reinforcement corrosion resistance about chloride ion that invade from outside. An experiment accelerated for the reinforcement corrosion through repeat of brine digestion and dry. Reinforcement corrosion investigated half cell potential method of measurement by ASTM C876 and corrosion area ratio. If granulated blast furnace slag metathesis ratio is high generally that looked the corrosion of reinforcement decreasing as a result that evaluate reinforcement corrosion by ASTM C876 canon in this research. It showed high resistance about reinforcement corrosion that use normal portland cement and increase the metathesis rate of granulated blast furnace slag, as a result that evaluate metathesis rate effect of granulated blast furnace slag according to cement kind. when the test piece split destroying, area rate of reinforcement corrosion showed about result of half cell potential measurement.

  • PDF

A Study on the Error Associated with Ventilation Rate Calculation Using Different Sampling Intervals (측정시간에 따른 거주주택의 환기량 계산 오류에 관한 연구)

  • 양원호;배현주;이기영;정문호
    • Journal of Environmental Health Sciences
    • /
    • v.26 no.3
    • /
    • pp.50-54
    • /
    • 2000
  • Ventilation rates can be measured directly by a tracer decay method, although little is known of the effects of different sampling intervals on decay rte calculations. This study determined variations in decay rates calculated by three techniques using residential ozone decay data. The calculation techniques were a regression technique, decay techniques using half-life and average-life, and finite difference techniques using two different time intervals. Variation associated with regression technique calculations for residential ozone decay rates based on data from both sample intervals were within 10% (2.81$\pm$1.88 hr-1). However, both half-life and finite difference technique calculations using a shorter-time interval were significantly different from those obtained with the regression technique(p<0.05). Therefore, the use of short sampling intervals in tracer decay may cause significant error in decay rate calculations.

  • PDF

A Study on Fatigue Damage Modeling Using Back-Propagation Neural Networks (역전파신경회로망을 이용한 피로손상모델링에 관한 연구)

  • 조석수;장득열;주원식
    • Transactions of the Korean Society of Automotive Engineers
    • /
    • v.7 no.6
    • /
    • pp.258-269
    • /
    • 1999
  • It is important to evaluate fatigue damage of in-service material in respect to assure safety and remaining fatigue life in structure and mechanical components under cyclic load . Fatigue damage is represented by mathematical modelling with crack growth rate da/dN and cycle ration N/Nf and is detected by X-ray diffraction and ultrasonic wave method etc. But this is estimated generally by single parameter but influenced by many test conditions The characteristics of it indicates fatigue damage has complex fracture mechanism. Therefore, in this study we propose that back-propagation neural networks on the basis of ration of X-ray half-value breath B/Bo, fractal dimension Df and fracture mechanical parameters can construct artificial intelligent networks estimating crack growth rate da/dN and cycle ratio N/Nf without regard to stress amplitude Δ $\sigma$.

  • PDF

A Study on Groundwater Quality and Biodegradability at the Petroleum Contaminated Sites of Kangwon and Gyeonggi Provinces, Korea (강원도 및 경기도 소재 유류오염지역의 수질특성, 발현 생분해능과 오염물질 저감속도)

  • Choi, Hyun-Mi;Lee, Jin-Yong;Park, Yu-Chul
    • Journal of Soil and Groundwater Environment
    • /
    • v.15 no.2
    • /
    • pp.24-33
    • /
    • 2010
  • This study focused on the groundwater quality, biodegradability and attenuation rate at the petroleum contaminated sites of Kangwon and Gyeonggi Provinces, Korea. For groundwater quality, Kangwon site showed chemical compositions of $Ca-SO_4+Cl$, $Ca-HCO_3$ and $Na+K-HCO_3$ types, while Gyeonggi site showed chemical compositions of $Ca-SO_4$, $Ca-HCO_3$ and $Na-HCO_3$ types. $Na+K-HCO_3$ and $Na-HCO_3$ types were detected only in February. Among many biodegradation processes, the majority was attributed to biodegradation from denitrification in both area. In Kangwon site, biodegradation from denitrification occupied 63.5%, and in Gyeonggi site it was 39.45%. Biodegradation from the most efficient aerobic respiration occupied 7.12% in Kangwon site, while Gyeonggi site in it did 27.29%. Point attenuation rate of BTEX in Gyeonggi site (GW-22) was 0.0182 $day^{-1}$, half life of BTEX was 84 days, and thus 124 days (0.34 year) would be required to clean up this site. Mean of point attenuation rate of TPH in Kangwon site was 0.0088 $day^{-1}$, mean of half life was 257 days, and thus 462 days would be required to clean up the site. Mean of point attenuation rate of TPH in Gyeonggi site was 0.0387 $day^{-1}$, mean of half life was 55 days, and thus remediation time was calculated as 99 days.

Colorimetric Analysis and Matching the Notation of the Munsell System for Reproduced Colors with Variable Dot Area Rates (망점면적비율에 대한 색인쇄물의 측색학적 해석과 Munsell 표색계와 관계)

  • 이상남
    • Journal of the Korean Graphic Arts Communication Society
    • /
    • v.1 no.1
    • /
    • pp.7-41
    • /
    • 1983
  • Reproduced colors which are half-tone printed at the rate of 10,20,30, ...100% half-tone dot area by each process ink- cyan, magenta, yellow and at the rates of 0,30,60, 100% half-tone dot areas by the mean color mixing of black, cyan, magenta and yellow, are colorimetric analyzed by make use of the 1931 CIE XYZ system of color specification and matching the Munsell color system. Espacially, magenta and secondary colors which are contained magenta, do not have good uniformity and proportionalization in the dominant wavelength and the excitation purity. Half-tone colors without reflection of blue light, are reproduced ideal color with the excitation purity 100% in wavelengths from 555nm to 600nm.

  • PDF