• 제목/요약/키워드: Half Life

검색결과 1,829건 처리시간 0.028초

계피 또는 데리스 추출물을 주원료로 하는 유기농업자재의 약효 성분 안정성 (The Shelf-life of Agricultural Organic Materials Containing Cinnamon or Derris Extract: Thermal Stability of Cinnamyl Derivatives and Rotenoids)

  • 최근형;진초롱;박병준;임성진;노진호;문병철;공승헌;김진효
    • 농약과학회지
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    • 제20권3호
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    • pp.197-202
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    • 2016
  • 계피 추출물의 지표성분으로 알려진 cinnamaldehyde와 cinnamyl alcohol, 데리스 추출물의 지표성분인 deguelin과 rotenone을 대상으로 유기농업자재 제품 중 안정성을 평가하였다. 시험은 $4^{\circ}C$, $23^{\circ}C$, $35^{\circ}C$, $45^{\circ}C$, $54^{\circ}C$에서 각각 진행하였으며, 계피 추출물을 주성분으로 하는 유기농업자재 중 고상제품(Biopesticide A, B)의 유효성분 반감기가 15.1-46.2 days로 액상제품(Biopesticide C, D)에 비해 보관 중 안정성이 높게 나타났다. 또한, 동일 제품 내에서는 cinnamaldehyde의 안정성이 cinnamyl alcohol보다 높은 것으로 나타났다. 데리스 추출물을 사용한 제품(Biopesticide E, F, G)의 rotenoid계 유효성분 반감기는 1.5-173 days로 제품별 보관온도에 따른 지표성분 안정성이 큰 차이를 나타내었으며, 동일 제품에서 deguelin과 rotenone의 안정성은 큰 차이를 나타내지 않았다.

생산단계 잔류허용기준설정을 위한 Flubendiamide 및 Pyriofenone의 딸기(Fragaria ananassa Duch.) 중 경시적 잔류특성 연구 (Establishment of Pre-Harvest Residue Limits (PHRL) of Flubendiamide and Pyriofenone on Strawberry (Fragaria ananassa Duch.))

  • 김희곤;김지윤;허경진;권찬혁;허장현
    • 농약과학회지
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    • 제21권1호
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    • pp.62-67
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    • 2017
  • 본 연구는 딸기 중 flubendiamide 및 pyriofenone의 경시적 잔류변화를 조사하여 반감기를 산출함으로써 생산단계 잔류허용기준을 설정하고자 수행하였다. Flubendiamide 및 pyriofenone 농약을 안전사용기준에 준하여 포장 1, 2에 각각 살포한 후 0, 1, 2, 3, 5, 7, 10일차에 딸기 시료를 채취하여 각각의 농약을 HPLC/UVD를 이용하여 분석하였다. 두 농약의 정량한계는 모두 $0.01mg\;kg^{-1}$이었고 $0.2mg\;kg^{-1}$$2mg\;kg^{-1}$ 수준에서 회수율은 각각 flubendiamide의 경우 $90.9{\pm}2.2%$$81.9{\pm}0.8%$이었으며, pyriofenone은 $87.7{\pm}2.1%$$85.3{\pm}1.1%$이었다. 딸기 중 flubendiamide의 생물학적 반감기는 포장 1, 2에서 각각 8.1일과 7.2일이었으며, pyriofenone의 경우 7.0일과 6.9일이었다. Flubendiamide 및 pyriofenone에 대하여 딸기 수확 10일 전 잔류량이 각각 $1.87mg\;kg^{-1}$$3.67mg\;kg^{-1}$으로 나타난다면 최종 잔류량은 MRL 수준 이하의 안전한 농산물을 생산할 수 있을 것으로 사료된다.

양앵두 왜성대목 'Gisela 5'의 기내번식을 위한 정단배양조건의 최적화 (Optimization of apical tip culture condition for In Vitro propagation of 'Gisela 5' dwarf cherry rootstock)

  • 쉬쥔핑;강인규;김창길;한증술;최철
    • Journal of Plant Biotechnology
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    • 제42권1호
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    • pp.49-54
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    • 2015
  • 본 연구의 결과를 바탕으로 중요한 양앵두 왜성대목의 하나인 'Gisela 5'의 미세번식을 위한 일련의 체계적 과정을 제안한다. 봄철 새롭게 생장한 신초로부터 절취한 정단조직을 IBA 0.5 mg/L와 BA 0.5 또는 1.0 mg/L가 첨가된 1/2MS배지에 치상하였을 때 hyperhydricity가 없고 왕성한 생장을 하는 정상 신초의 획득율이 90%에 달하였다. 다음단계로, 기내에서 유지된 모식물체로부터 채취한 신초를 IBA 0.5 mg/L와 BA 0.5 mg/L가 첨가된 전MS배지에 이식하면 약 9배에 이르는 수준으로 신초가 증식되었다. 증식된 신초는 IBA 2.0 mg/L가 첨가된 1/2MS배지로 이식하면 지상부의 정상생장과 함께 왕성하게 발근하였다. 발근한 유식물체는 비교적 손쉽게 최종적으로 기외 순화시킬 수 있었는데, 기외 이식 상토로는 버미큘라이트, 펄라이트 및 피트모스의 혼합비율을 1:1:1로 하는 것이 가장 적합하였다. 본 연구의 결과가 양앵두 재배와 양앵두 대목의 생산에 유용하게 활용되기를 기대한다.

부산지역(釜山地域) 치과기공사(齒科技工士)의 보수교육(補修敎育) 개선(改選)에 관(關)한 조사연구(調査硏究) (A Study of Investigation about Improvement of Life Long Education for the Dental Technicians in Pusan)

  • 정인성
    • 대한치과기공학회지
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    • 제12권1호
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    • pp.73-93
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    • 1990
  • The study objected to the 120 persons out of 360 persons who have registered under the association of the dental technicians in Pusan to grasp contents about improvement of life long education of the present day of November, 1987, and its results, which we have acquired by this study were as follows : 1. A sense of satisfaction toward the system of life long education appeared as unsatisfaction and its unsatisfaction decreased from the rate of member's attendance or exam. marks, the contents of education, and place of education. 2. The problem of the exam. mark which derived by the presence by the substitute appeared which 46.7 percent(56 persons), lack of opportunity for the recompletion at branch association appeared which 19.2%(23 persons), given 4. exam. marks at the over all scientific contest was appeared 14.2 percent(17 persons), relation which legal treatment when ones didn't completed exam. mark was appeared 10.8 percent(13 persons) and lastly, appeared 8.3 percent (10 persons) with time of delivery of the exam mark card. 3. The frequency of the opening for the life long education which related with the rate of members attendance was fixed as nowadays two times per annually, but they perferred the opening per academic blanch once out of the firest half year and the latter half of the year and, they liked the openings at the first week or second week and preferred the holding on saturdays and sundays. 4. The subject of the life long education have appeared the opinion that the thesis was lop-sided toward the allocation of time schedule of lecture appeared the opinion of which they perferred the rate of an hour of cultural subject and two hours of major studies, and invitation for an instructor they preferred one dentist, one member, one dean for the cultural subject, and there are lots of opinions which they wished display of materials. 5. A sence of satisfaction about the place they perferred was decreased such as ; an auditorium concerned of the colleges was 46.7 Percent(56 Persons), hotels 26.7 Percent(32 Persons), an auditorium of the general hospital 20 percent(24 persons) 6. And lastly, there are lots of opinions who have required the necessities to constitute for the academic branch.

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스칸디나비아 노인용 코하우징 주민의 이주동기와 생활만족도의 성별 차이 (Differences between Male and Female in Moving Motivation and Life Satisfaction of Senior Cohousing Residents in Scandinavia)

  • 최정신;조재순
    • 가정과삶의질연구
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    • 제24권1호
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    • pp.117-128
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    • 2006
  • The purpose of this research was to find out the differences in the moving motivation and life satisfaction of senior cohousing communities between male and female residents in Scandinavia, especially in Sweden and Denmark. Senior cohousing is an attractive housing alternative for the aged 55 and over who looks for sharing one's life with neighbors. The 655 survey questionnaires out of 960 had replied from 14 Seniorbofrellesskaber in Denmark and 11 seniorhus within SABO sector and 8 housing cooperatives initiated by the Seniorgarden Housing Company in Sweden during April to May, 2002. The data were analyzed by SPSS win program, using frequencies, percentiles, cross-tabulations, and Pearson's correlations. The results showed that the senior cohousing residents were generally healthy and age of 70's years old and nearly half lived with a spouse. The male residents lived with a spouse about 2 times more than did the female. The residents had very strong motivation to move into the community and very high life satisfaction. Most aspects of moving motivation were not differed by the sex of the residents. However, male residents were more likely than female to be motivated to move in by becoming a pensioner, while female residents were more likely than male to be motivated by being a widow, looking for safety, or avoiding loneliness. These different motivation to move in by sex become more clear when general characteristics such as age, health status, living with or without a spouse, or country were controlled. Female residents were more likely than male to live' dream life' in the senior cohousing community. The stronger the moving motivation, the higher the life satisfaction in the community.

추출 방법과 조건에 따른 소나무 지엽 추출효율 변화 (Changes in Extraction Efficiency of Pine Needles depending on Extraction Method and the Condition)

  • 김동성;김형민;성용주;강석구;강호양;이준우;김세빈;박관수
    • 펄프종이기술
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    • 제48권1호
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    • pp.93-99
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    • 2016
  • The extraction efficiency depending on the extracting methods and the conditions of extraction was investigated. The common steam extraction was compared to the distillation extraction method. The effects of the samples size and the extraction time on the extract yield were also investigated by using UV-Vis spectrophotometer. One of the functional components of pine needle extract as the natural phenol base components were detected by the UV-VIS at around 235 nm wavelength range. The absorbance intensity at around 235 nm wavelength of the pine needle extract was used as the indicator of the extraction efficiency in this experiment. The distillation extraction showed the higher extract yield than the steam extraction. The grinding treatment of pine needles also resulted in the better extract performance, but the severe grinding showed a little decrease in the extract yield especially in case of the distillation extraction method. More than half of the extract was collected at the first stage of the extraction, that was the first 15 minutes in the total 60 minutes extraction.

한국 생명보험산업의 정보화투자와 비용절감 (The Impact of Information Technology Investment on Cost Reduction in Korean Insurance Industry)

  • 이영수;정군오
    • 기술혁신학회지
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    • 제9권1호
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    • pp.175-198
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    • 2006
  • 한국 생명보험산업에 있어서 정보화투자 효과분석은 향후 정보화투자의 방향설정과 관련하여 매우 중요하다. 이를 위해서 본 연구는 생명보험산업의 다생산물결합 비용함수를 테일러 전개한 제2차 초월대수비용함수를 사용하여 SURE방법으로 정보화자본스톡의 비용탄력성을 추정하였다. 분석자료는 총 33개 생보사를 대상으로 1991-2003년간의 패널자료를 사용하였다. 분석결과는 정보화투자 효과가 개별생보사 마다 차이는 있으나 분석대상 생보사들의 절반정도는 정보화투자로 비용이 절감되는 것으로 나타났다. 한편, 대형생보사는 정보자본스톡이 증가하면, 대형생보사의 비용은 감소하는 것으로 제시되었으나, 중소형생보사와 외국계생보사는 정보자본스톡이 증가할수록 비용이 증가하는 것으로 제시되었다. 또한, 정보예산이 증가할수록 정보자본과 전산직원을 동시에 증가시키고 있으나, 정보자본의 가격이 전산직원의 가격보다 더 크게 하락함에 따라 정보자본을 전산직원 보다 더 크게 증가시키는 것으로 나타났다.

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학령기 자녀가 있는 결혼이민자 여성의 생활만족도 예측 변인 (Predictors of life satisfaction in marriage migrant wives with school-aged children)

  • 성미애;최여진
    • 가족자원경영과 정책
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    • 제21권1호
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    • pp.1-18
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    • 2017
  • This study examined the predictors of life satisfaction of marriage migrant wives with school-aged children in South Korea. For this purpose, we draw data from the 2015 National Survey on Multi-cultural Families (NSMF). The target group was marriage migrant wives who were in a first marriage and had school-aged children (N=3,004). We used OLS regression to examine the predictors of the target group's life satisfaction with the SPSS 18.0 program. The results are as follows. First, marriage migrant wives with school-aged children had maintained their marriage for at least 14 years. They were satisfied with their relationships with both their spouses and their children. Also, they were satisfied with their spouse's child care roles. They did not support the multi-cultural policy of assimilation. Their Korean proficiency was slightly higher than the middle level. More than half had jobs and had not attended a parent meeting. Second, although they were satisfied with their everyday lives, their levels of life satisfaction were less than that of migrant wives with children below 5 years of age. Third, all variables explained 38.8% of the life satisfaction experienced by marriage migrant wives with school-aged children. Satisfaction with their spouses, subjective health, satisfaction of spouse's child care role, monthly family income, satisfaction with their children, experience attending a parents meeting, and Korean proficiency were positively associated with the life satisfaction of this target group. The findings of this study are significant because they can provide certain implications for family life education and policy within a multi-cultural society.

2층 고무/코드 적층판의 피로 수명 예측 (Prediction of Fatigue Life in 2 Ply Rubber/Cord Laminate)

  • 임동진;이윤기;윤희석;김민호
    • Composites Research
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    • 제16권3호
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    • pp.9-17
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    • 2003
  • 타이어 벨트층내의 코드간 균열연결 및 층간균열진전을 모사하기 위해 자유단을 갖는 2층 고무/코드 적층시험편에 대한 4~11mm 변위제어 실험을 수행하였다. 자유단의 코드간 균열연결시의 폭방향 균열진전량은 45$^{\circ}$ 경사진 코드들간 길이의 절반에 도달할 때의 측정값으로 하였으며, 이는 탐침법에 의해 측정되었다 또한, 자유단에서 코드들간 균열연결을 모사하기위해 2차원의 이상화된 모델링 기법을 고안하였다. 이론수명은 테어링에너지(균열파단면의 단위면적당 방출에너지)를 이용하여 코드간 균열연결수명(임계값)과 이후 최종파손까지의 수명으로 구분하였으며, 이들을 각기 실험값과 비교하였다. 임계값까지의 수명예측은 실험과 비교하여 약 20%, 최종파손까지 약 65%의 오차가 발생하였다. 따라서, 전체 이론수명은 실험과 비교하여 약 45%의 오차를 발생하였다.

Establishment of an analytical method for butaphosphan (BTP), a stress-attenuating agent, and its application in the preliminary pharmacokinetic evaluation of residues in olive flounder Paralichthys olivaceus

  • Lee, Ji-Hoon;Bae, Jun Sung;Lee, Chae Won;Yang, Chan Yeong;Choi, Ji-Sung;Choi, Sang-Hoon;Kang, Yue-Jai;Park, Kwan Ha
    • Fisheries and Aquatic Sciences
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    • 제23권4호
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    • pp.10.1-10.10
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    • 2020
  • Background: Butaphosphan (BTP) has recently been introduced into the Korean aquaculture sector as a stressattenuating agent. In this study, a sensitive chemical analytical method was established for the detection of BTP in the olive flounder (Paralichthys olivaceus) tissues. Methods: Utilizing a method employing liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS), detection sensitivity, specificity, and precision were satisfactorily established. Temporal changes in the BTP plasma and muscle concentrations were assessed after a single intramuscular injection of BTP (50 and 150 mg/kg) to the olive flounder maintained at 13 ℃ or 22 ℃. Results: High BTP plasma levels were achieved immediately after the injection, and the drug was rapidly eliminated. Additionally, plasma BTP levels were markedly dependent on the elimination rate, which, in turn, seemed dependent on the water temperature, with the drug elimination half-life and mean residence time significantly shorter at 22 ℃ than 13 ℃. Overall, muscle BTP levels were markedly lower than the plasma levels. Notably, muscle levels were not influenced by water temperatures. Muscle BTP concentrations were used to estimate the necessary withdrawal period for drugs used in food fish, with BTP levels maintained far below the possible hazardous limit. Conclusions: In conclusion, the established LC-MS/MS method can be used for BTP residue detection with high sensitivity and reproducibility.