• Journal of the Korean Society of Marine Environment & Safety
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• v.24 no.1
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• pp.92-100
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• 2018

Vortical systems are considered a main feature to sustain turbulence in a boundary layer through interaction. Such turbulent structures result in frictional drag and erosion or vibration in engineering applications. Research for controlling turbulent flow has been actively carried out, but in order to show the effect of vortices in a turbulent boundary layer, it is necessary to clarify the mechanism by which turbulent energy is transferred. For this purpose, it is convenient to demonstrate and capture phenomena in a laminar boundary layer. Therefore, in this study, the interactions of disturbed flow around a hemisphere on a flat plate in laminar flow were analyzed. In other words, a street of hairpin vortices was generated following a wake region formed after flow separation occurred over a hemisphere. Necklace vortices surrounding the hemisphere also appeared due to a strong adverse pressure gradient that brought high momentum fluid into the wake region thereby leading to an increase in the frequency of hairpin vortices. To mitigate the effect of these necklace vortices, local suction control was applied through a hole in front of the hemisphere. Flow visualization was recorded to qualitatively determine flow modifications, and hot-film measurements quantitatively supported conclusions on how much the power of the hairpin vortices was reduced by local wall suction.

• Journal of Conservation Science
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• v.37 no.3
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• pp.270-281
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• 2021

The Yongjam of Oejae, Yi Dan-ha's wife, is an ornamental hairpin with a dragon-shaped engraving; designated as National Folklore Cultural Heritage No. 4. It is also a component of the ceremonial costume, and an artifact of great value as it clearly identifies the position of the wearer and the period of this artifact. The Yongjam has been well preserved in general; however, various pollutants and corrosive products have affected the engraved patterns, requiring conservation treatment. Furthermore, a non-destructive analysis was conducted to identify the components of the materials and the manufacturing techniques used in the ornament. The Yongjam is hollow inside to reduce its weight when placed in the hair and has a color contrast of gold, red, and black. The decorative part and the body were made separately. That is, the body was made from an alloy of copper, silver, and zinc, and its joint was elaborately connected without any overlaps. In the decorative part, different alloy ratios were identified in the dragon's face, beard, horn, body, and fin. Further, for the dragon's face with its delicate patterns, an alloy of silver and copper was used, likely to make the face appear as realistic as possible.

• Journal of the Korean Society of Radiology
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• v.84 no.6
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• pp.1361-1366
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• 2023

The persistent primitive olfactory artery (PPOA) is a rare variant of the anterior cerebral artery, first reported in 1979. It reportedly has a high correlation with the development of aneurysms, owing to the hemodynamic stress induced by the structural characteristics of the hairpin turn. Herein, we present a rare case of PPOA type 4 with a fusiform aneurysm at the hairpin turn segment in a 46-year-old female with occasional headaches. Time-of-flight MR angiography and transfemoral cerebral angiography revealed an unusual branch arising from the left A1 segment, running anteromedially along the ipsilateral olfactory tract, and turning the hairpin posterior to the olfactory bulb. This branch continued into the left accessory middle cerebral artery, and a fusiform aneurysm was observed at the hairpin segment. No further treatment was performed, and follow-up imaging was recommended. Nevertheless, it is essential to recognize and diagnose these rare variations.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.28 no.6
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• pp.672-681
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• 2004

Direct numerical simulation was carried out to study the vortical structures of the flow around a wall-mounted cube in a channel at Re=1,000 and Re=3,500 based on cubic height and bulk mean velocity. The cubic obstacle is situated in the entrance region of the channel flow where the boundary layers are developing. Upstream of the obstacle, steady and unsteady laminar horseshoe vortex systems are observed at Re=1,000 and Re=3,500, respectively; the near-wake flow is turbulent in both cases. The flow separates at each leading sharp edge of the cube, and subsequent vortex roll-up is noticed in the corresponding free-shear layer. The vortex shedding from the upper leading edge (upper vortices) and that from the two lateral leading edges (lateral vortices) are both quasi-periodic and their frequencies are computed. The upper and lateral vortices further develop into hairpin and Λ vortices, respectively. A series of instantaneous contours of the second invariant of velocity gradient tensor helps us identify spatial and temporal behaviors of the vortices in detail. The results indicate that the length and time scales of the vortical structures at Re=3,500 are much shorter than those at Re:1,000. Correlations between the upper and lateral vortices are also reported.

• Molecules and Cells
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• v.27 no.6
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• pp.657-665
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• 2009

The ovomucoid pre-mRNA has been folded into mini-hairpins adaptable for the RNA recognition motif (RRM) protein binding. The number of mini-hairpins were 372 for pre-mRNA and 83-86 for mature mRNA. The spatial arrangements are, in average, 16 nucleotides per mini-hairpin which includes 7 nt in the stem, 5.6 nt in the loop and 3.7 nt in the inter-hairpin spacer. The constitutive splicing system of ovomucoid-pre-mRNA is characterized by preferred order of intron removal of 5/6 > 7/4 > 2/1 > 3. The 5' splice sites (5'SS), branch point sequences (BPS) and 3' splice sites (3'SS) were identified and free energies involved have been estimated in 7 splice sites. Thermodynamic barriers for splice sites from the least (|lowest| -Kcal) were 5, 4, 7, 6, 2, 1, and 3; i.e., -18.7 Kcal, -20.2 Kcal, -21.0 Kcal, -24.0 Kcal, - 25.4 Kcal, -26.4 Kcal and -28.2 Kcal respectively. These are parallel to the kinetic data of splicing order reported in the literature. As a result, the preferred order of intron removals can be described by a consideration of free energy changes involved in the spliceosomal assembly pathway. This finding is consistent with the validity of hnRNP formation mechanisms in previous reports.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.4 no.3
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• pp.557-564
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• 2000

A microstrip band-pass filter using cross-coupled resonators is designed and studied experimentally. The cross-coupled microstrip hairpin resonator filters exhibit ripples in both passband and stopband. These ripples can improve both frequency selectivity and insertion loss. The cross-coupled filters are not only simple and compact in configuration, but also have great flexibility to form filters into a variety of size. In this paper, a microstrip band-pass filter using cross-coupled resonators is designed at the center frequency of 1.8GHz with bandwidth of 5.0% using Ensemble software. The experimental results show that the bandwidth is about 4.53% at 1.8GHz.

• Journal of computational fluids engineering
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• v.16 no.1
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• pp.83-89
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• 2011

Laminar flow over a cube near a plane wall is numerically investigated in order to understand the effects of the cube-wall gap on the flow characteristics as well as the drag and lift coefficients. The main focus is placed on the three-dimensional vortical structures and its relation to the lift force applied on the cube. Numerical simulations are performed for the Reynolds numbers between 100 and 300, covering several different flow regimes. Without a wall nearby, the flow at Re=100 is planar symmetric with no vortical structure in the wake. However, when the wall is located close to the cube, a pair of streamwise vortices is induced behind the cube. At Re=250, the wall strengthens the existing streamwise vortices and elongates them in the streamwise direction. As a result, the lift coefficients at Re=100 and 250 increase as the cube-wall gap decreases. On the other hand, without a wall, vortex shedding takes place at Re=300 in the form of a hairpin vortex whose strength changes in time. The head of hairpin vortex or loop vortex, which is closely related to the lift force, seems to disappear due to the nearby wall. Therefore, unlike at Re=100 and 250, the lift coefficient tends to decrease more or less as the cube approaches the wall.

• Journal of computational fluids engineering
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• v.17 no.2
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• pp.93-99
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• 2012

The present study focuses on the case of developing flow with in a channel containing a long array of sinusoidal waves (2a/${\lambda}$=0.1, ${\lambda}$=h, ${\lambda}$ is the wavelength, 2a is the wave height, h is the mean channel depth) at the bottom wall. The Reynolds number defined with channel height, h and the mean velocity, U, is Re=6,700. The channel is sufficiently long such that transition is completed and the flow is fully developed over the downstream half of the channel. For the case of an incoming steady flow with no resolved turbulence, the instantaneous flow fields in the transition region are characterized by the formation of arrays of highly-organized large-scale hairpin vortices whose dimensions scale with that of the roughness elements. The paper explains the mechanism for the formation of these arrays of hairpin vortices and shows these eddies play the primary role in the formation of the large-scale streaks of high and low velocity over the wavy wall region. The presence of resolved turbulence in the incoming flow, reduces the streamwise distance needed for the streaks to develop over the wavy region, but does not affect qualitatively the transition process. In the fully-developed region, isolated and trains of large-scale hairpins play an important role in the dynamics of the streaks over the wavy wall.

• International Journal of Aeronautical and Space Sciences
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• v.18 no.1
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• pp.48-55
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• 2017

Aeroacoustic computation of a fully-developed turbulent pipe flow at $Re_{\tau}=175$ and M = 0.1 is conducted by LES/LPCE hybrid method. The generation and propagation of acoustic waves are computed by solving the linearized perturbed compressible equations (LPCE), with acoustic source DP(x,t)/Dt attained by the incompressible large eddy simulation (LES). The computed acoustic power spectral density is closely compared with the wall shear-stress dipole source of a turbulent channel flow at $Re_{\tau}=175$. A constant decaying rate of the acoustic power spectrum, $f^{-8/5}$ is found to be related to the turbulent bursts of the correlated longitudinal structures such as hairpin vortex and their merged structures (or hairpin packets). The power spectra of the streamwise velocity fluctuations across the turbulent boundary layer indicate that the most intensive noise at ${\omega}^+$ < 0.1 is produced in the buffer layer with fluctuations of the longitudinal structures ($k_zR$ < 1.5).

• BMB Reports
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• v.41 no.4
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• pp.294-299
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• 2008

Elevated expression of SMYD3 is a frequent genetic abnormality in several malignancies. Few studies knocking down SMYD3 expression in cervical carcinoma cells have been performed to date. In this paper, we established an inducible short hairpin RNA expression system to examine its role in maintaining the malignant phenotype of HeLa cells. After being induced by doxycycline, SMYD3 mRNA and protein expression were both reduced, and significant reductions in cell proliferation, colony formation and migration/invasion activity were observed in the SMYD3-silenced HeLa cells. The percentage of cells in sub-G1 was elevated and DNA ladder formation could be detected, indicating potent induction of apoptosis by SMYD3 knockdown. These findings imply that SMYD3 plays crucial roles in HeLa cell proliferation and migration/invasion, and that it may be a useful therapeutic target in human cervical carcinomas.