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Elastica of Cantilever Column with Constant Volume Subjected to Combined Loads (조합하중을 받는 일정체적 캔틸레버 기둥의 정확탄성곡선)

  • Lee, Byoung-Koo;Li, Guangfan;Yoon, Hee-Min
    • Journal of the Computational Structural Engineering Institute of Korea
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    • v.20 no.5
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    • pp.581-592
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    • 2007
  • This paper deals with the elastica of deflected cantilever column with the constant volume. The columns are subjected to combined loads consisted of an axial compressive load and a couple moment at the free end. Differential equations governing the elastica of such column are derived, in which both the effects of taper type and shear deformation are included. Three kinds of taper types are considered: linear, parabolic and sinusoidal tapers. Differential equations are solved numerically to obtain the elastica of objective columns. The effects of various system parameters on the elastica are investigated extensively. Experimental studies were carried out in order to verify the theoretical results of non-linear behavior of the elasticas.

AN EXTREMAL PROBLEM ON POTENTIALLY $K_{r,r}$-ke-GRAPHIC SEQUENCES

  • Chen, Gang;Yin, Jian-Hua
    • Journal of applied mathematics & informatics
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    • v.27 no.1_2
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    • pp.49-58
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    • 2009
  • For $1{\leq}k{\leq}r$, let ${\sigma}$($K_{r,r}$ - ke, n) be the smallest even integer such that every n-term graphic sequence ${\pi}$ = ($d_1$, $d_2$, ..., $d_n$) with term sum ${\sigma}({\pi})$ = $d_1$ + $d_2$ + ${\cdots}$ + $d_n\;{\geq}\;{\sigma}$($K_{r,r}$ - ke, n) has a realization G containing $K_{r,r}$ - ke as a subgraph, where $K_{r,r}$ - ke is the graph obtained from the $r\;{\times}\;r$ complete bipartite graph $K_{r,r}$ by deleting k edges which form a matching. In this paper, we determine ${\sigma}$($K_{r,r}$ - ke, n) for even $r\;({\geq}4)$ and $n{\geq}7r^2+{\frac{1}{2}}r-22$ and for odd r (${\geq}5$) and $n{\geq}7r^2+9r-26$.

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Theoretical and experimental study on deflection of steel-concrete composite truss beams

  • Wang, Junli;Li, Tian;Luo, Lisheng
    • Steel and Composite Structures
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    • v.29 no.1
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    • pp.91-106
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    • 2018
  • This paper investigates the deflection of the steel-concrete composite truss beam (SCCTB) at the serviceability limit state. A precise solution for the distributed uplift force of the SCCTB, considering five different loading types, is first derived based on the differential and equilibrium equations. Furthermore, its approximate solution is proposed for practical applications. Subsequently, the shear slip effect corresponding to the shear stiffness of the stub connectors, uplift effect corresponding to the axial stiffness of the stub connectors and shear effect corresponding to the brace deformation of the steel truss are considered in the derivation of deflection. Formulae for estimating the SCCTB deflection are proposed. Moreover, based on the proposed formulae, a practical design method is developed to provide an effective and convenient tool for designers to estimate the SCCTB deflection. Flexure tests are carried out on three SCCTBs. It is observed that the SCCTB stiffness and ultimate load increase with an increase in the shear interaction factor. Finally, the reliability of the practical design method is accurately verified based on the available experimental results.

Correlation of CT Perfusion Images with VEGF Expression in Solitary Brain Metastases

  • Zhang, Jian-Hua;Wang, Ming-Sheng;Pan, Hai-Hong;Li, Shu-Feng;Wang, Zhong-Qiu;Chen, Wang-Sheng
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.4
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    • pp.1575-1578
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    • 2012
  • Objectives: To obtain permeability surface (PS) values using multi-slice helical CT perfusion imaging and to evaluate the spatial distribution correlation between PS values and vascular endothelial growth factor (VEGF) expression in solitary brain metastases. Methods: Imaging was performed on 21 patients, PS values being calculated from the central, border and peripheral parts of tumours. VEGF expression was determined by immunohistochemical staining. Results: Rim enhancement was found in 16 cases, the border of the tumour featuring PS elevation with high VEGF expression in 13 cases. In the 5 cases with nodular enhancement, the border and the central part had high permeability and VEGF expression was high in all cases, the correlation being significant (P<0.01). Conclusion: VEGF expression in brain metastases positively correlates with PS values from CT perfusion imaging, so that the latter can be used in the surveillance of angiogenic activity in brain metastases.

Porcine growth hormone induces the nuclear localization of porcine growth hormone receptor in vivo

  • Lan, Hainan;Liu, Huilin;Hong, Pan;Li, Ruonan;Zheng, Xin
    • Asian-Australasian Journal of Animal Sciences
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    • v.31 no.4
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    • pp.499-504
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    • 2018
  • Objective: Recent studies have challenged the traditional paradigm that growth hormone receptor (GHR) displays physiological functions only in the cell membrane. It has been demonstrated that GHR localizes to the cell nucleus and still exhibits important physiological roles. The phenomenon of nuclear localization of growth hormone (GH)-induced GHR has previously been described in vitro. However, until recently, whether GH could induce nuclear localization of GHR in vivo was unclear. Methods: In the present study, we used pig as an animal model, and porcine growth hormone (pGH) or saline was injected into the inferior vena cava. We subsequently observed the localization of porcine growth hormone receptor (pGHR) using multiple techniques, including, immunoprecipitation and Western-blotting, indirect immunofluorescence assay and electronmicroscopy. Results: The results showed that pGH could induce nuclear localization of pGHR. Taken together, the results of the present study provided the first demonstration that pGHR was translocated to cell nuclei under pGH stimulation in vivo. Conclusion: Nuclear localization of pGHR induced by the in vivo pGH treatment suggests new functions and/or novel roles of nuclear pGHR, which deserve further study.

Dynamics of shearing force and its correlations with chemical compositions and in vitro dry matter digestibility of stylo (Stylosanthes guianensis) stem

  • Zi, Xuejuan;Li, Mao;Zhou, Hanlin;Tang, Jun;Cai, Yimin
    • Asian-Australasian Journal of Animal Sciences
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    • v.30 no.12
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    • pp.1718-1723
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    • 2017
  • Objective: The study explored the dynamics of shearing force and its correlation with chemical compositions and in vitro dry matter digestibility (IVDMD) of stylo. Methods: The shearing force, diameter, linear density, chemical composition, and IVDMD of different height stylo stem were investigated. Linear regression analysis was done to determine the relationships between the shearing force and cut height, diameter, chemical composition, or IVDMD. Results: The results showed that shearing force of stylo stem increased with plant height increasing and the crude protein (CP) content and IVDMD decreased but fiber content increased over time, resulting in decreased forage value. In addition, tall stem had greater shearing force than short stem. Moreover, shearing force is positively correlated with stem diameter, linear density and fiber fraction, but negatively correlated with CP content and IVDMD. Conclusion: Overall, shearing force is an indicator more direct, easier and faster to measure than chemical composition and digestibility for evaluation of forage nutritive value related to animal performance. Therefore, it can be used to evaluate the nutritive value of stylo.

Tubeimoside-1 suppresses breast cancer metastasis through downregulation of CXCR4 chemokine receptor expression

  • Peng, Yaojin;Zhong, Yan;Li, Gao
    • BMB Reports
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    • v.49 no.9
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    • pp.502-507
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    • 2016
  • To examine the effect of TBMS1on breast cancer metastasis, and investigate the potential mechanism by which Tubeimoside-1 (TBMS1) inhibits the CXCR4 expression in breast cancer cells. The expression of CXCR4 in breast cancer cell lines was determined by immunoblotting and real-time PCR. The effect of TBMS1 on NF-κB binding activity was evaluated by EMSA assay and ChIP analysis. Cell proliferation and invasion were analyzed by MTT assay and transwell invasion assay, respectively. The effect of TBMS1 on breast cancer metastasis was further evaluated in a metastasis model of nude mice. TBMS1 suppressed the expression of CXCR4 through inhibition of NF-κB binding activity. TBMS1 inhibited CXCL12-induced invasion in breast cancer cells, while ectopic expression of CXCR4 abolished the inhibitive activity of TBMS1. TBMS1 suppressed breast cancer metastasis in the metastatic model of nude mice. TBMS1 suppressed the CXCR4-mediated metastasis of breast cancer by inhibiting NF-κB binding activity.

Species Diversity and Seasonal Distribution of Culicoides spp. (Diptera: Ceratopogonidae) in Jeju-do, Republic of Korea

  • Kim, Heung Chul;Bellis, Glenn A.;Kim, Myung-Soon;Klein, Terry A.;Gopurenko, David;Cai, Du-Cheng;Seo, Hyun-Ji;Cho, In-Soo;Park, Jee-Yong
    • Parasites, Hosts and Diseases
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    • v.53 no.4
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    • pp.501-506
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    • 2015
  • Biting midges belonging to the genus Culicoides (Diptera: Ceratopogonidae) were collected by Mosquito $Magnet^{(R)}$ and black light traps at 5 sites on Jeju-do, Republic of Korea (Korea), from May-November 2013 to determine species diversity and seasonal distribution. A total of 4,267 specimens were collected, of which 99.9% were female. The most common species was Culicoides tainanus (91.8%), followed by C. lungchiensis (7.2%) and C. punctatus (0.6%), while the remaining 4 species accounted for <0.5% of all Culicoides spp. that were collected. High numbers of C. tainanus were collected in May, followed by decreasing numbers through August, and then increasing numbers through November when surveillance was terminated. Peak numbers of C. lungchiensis were collected during September, with low numbers collected from May-August and October-November. The presence of C. lungchiensis in Korea was confirmed by morphological and molecular analyses.

The Robust Derivative Code for Object Recognition

  • Wang, Hainan;Zhang, Baochang;Zheng, Hong;Cao, Yao;Guo, Zhenhua;Qian, Chengshan
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • v.11 no.1
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    • pp.272-287
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    • 2017
  • This paper proposes new methods, named Derivative Code (DerivativeCode) and Derivative Code Pattern (DCP), for object recognition. The discriminative derivative code is used to capture the local relationship in the input image by concatenating binary results of the mathematical derivative value. Gabor based DerivativeCode is directly used to solve the palmprint recognition problem, which achieves a much better performance than the state-of-art results on the PolyU palmprint database. A new local pattern method, named Derivative Code Pattern (DCP), is further introduced to calculate the local pattern feature based on Dervativecode for object recognition. Similar to local binary pattern (LBP), DCP can be further combined with Gabor features and modeled by spatial histogram. To evaluate the performance of DCP and Gabor-DCP, we test them on the FERET and PolyU infrared face databases, and experimental results show that the proposed method achieves a better result than LBP and some state-of-the-arts.

Atmospheric Corrosion of 7B04 Aluminum Alloy in Marine Environments

  • Zhang, Xiaoyun;Liu, Ming;Lu, Feng;Liu, Minghui;Sun, Zhihua;Tang, Zhihui
    • Corrosion Science and Technology
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    • v.17 no.1
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    • pp.6-11
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    • 2018
  • Outdoor exposure tests using of 7B04 aluminium alloy samples including plate, tensile and various SCC samples were carried out in Tuandao station, Shandong province (East of China) and Wanning station, Hainan province (South of China). Corrosion characteristics including weight loss, microstructure, tensile strength and SCC susceptibility were investigated. The corrosion rates in Tuandao and Wanning showed high to low and the corrosion rates changed to the following equation of $w=at^b$ (b<1). The corrosion of 7B04 aluminium alloy in Wanning was more serious than that in Tuandao. Pitting appeared at early stage of expose test, and it can be changed to general corrosion with test time extension. The 7B04 aluminium alloy of which specimen shapes are forging and thick plate also showed SCC (Stress corrosion cracking) in the marine atmosphere. The higher SCC sensitivity was observed in Wanning station than in Tuandao station. The 7B04 aluminium alloy with a high stress level was more sensitive to SCC. Intergranular and transgranular or a mixed mode of cracking can be observed in different marine exposure.