• Clean Technology
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• v.9 no.3
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• pp.125-132
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• 2003

Activity improvement of Ni metal catalysts for carbon dioxide reforming was studied using HY-zeolite as the main supporter. As the reaction temperature increased, $CH_4$ and $CO_2$ conversions increased, and conversions higher than 80% was obtained above $700^{\circ}C$. As the Ni loading increased, the catalyst activity increased, and the highest activity was shown for the Ni loading of 13wt%. The HY-zeolite support showed the highest intial conversions of $CH_4$ and $CO_2$, but it showed faster deactivation than a ${\gamma}-Al_2O_3$ support. Nevertheless, it maintained the $CH_4$conversion higher than 80% after 24 hr reaction. The effect of promoters such as Mg, Mn, K, and Ca was also studied. It was observed that the Mg promotor exhibited the highest catalyst activity and less deactivation compared with Mn, K and Ca. After 24hr reaction, The optimum Mg content was found to be 5wt%.

• Journal of Microbiology and Biotechnology
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• v.27 no.12
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• pp.2237-2240
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• 2017

In the present study, we investigated the effect of tyndallized HY7712 (tHY7712) on the expression of Th cell specific transcription factors and cytokines in whole-body ${\gamma}$-irradiated mice. Oral administration of tHY7712 strongly recovered the ${\gamma}$-irradiation-suppressed expression of helper T (Th) cell- and regulatory T cell-related transcription factors and cytokines, such as T-bet, Foxp3, IFN-${\gamma}$, TNF-${\alpha}$, and IL-10, and suppressed Th2 cell-associated transcription factor and cytokine GATA3 and IL-5, respectively. Furthermore, compared with the control, tHY7712 treatment also restored ${\gamma}$-irradiation-impaired natural killer and cytotoxic T cell activities against YAC-1 tumor cells to 97.8% and 98.6%, respectively.

• Journal of Microbiology and Biotechnology
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• v.10 no.5
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• pp.643-650
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• 2000

A new aniline-utilizing microorganism, strain HY1 obtained from an orchard soil, was characterized by using the BIOLOG system, an analysis of the total cellular fatty acids, and a 16S rDNA sequence. Strain HY1 was identified as a Burkholderia species, and was designated Burkholderia sp. HY1. GC and HPLC analyses revealed that Burkholderia sp. HY1 was able to degrade aniline to produce catechol, which was subsequently converted to cis,cis-muconic acid through an ortho-ring fission pathway under aerobic conditions. Strain HY1 exhibited a drastic reduction in the rate of aniline degradation when glucose was added to the aniline media. However, the addition of peptone or nitrate to the aniline media dramatically accelerated the rate of aniline degradation. A fatty acid analysis showed that strain HY1 was able to produce lipids 16:0 2OH, and 11 methyl 18:1 ${\omega}7c$ approximately 3.7-, 2.2-, and 6-fold more, respectively, when grown on aniline media than when grown on TSA. An analysison the alignment of a 1,435 bp fragment. A phylogenetic analysis of the 16S rDNA sequence based on a 1,420 bp multi-alignment sowed of the 16s rDNA sequence revealed that strain HY1 was very closely related to Burkholderia graminis with 95% similarity based that strain HY1 was placed among three major clonal types of $\beta$-Proteobacteria, including Burkholderia graminis, Burkholderia phenazinium, and Burkholderia glathei. The sequence GAT(C or G)${\b{G}}$, which is highly conserved in several locations in the 16S rDNA gene among the major clonal type strains of $\beta$-Proteobacteria, was frequently replaced with GAT(C or G)${\b{A}}$ in the 16S rDNA sequence from strain HY1.

• Proceedings of the Korea Water Resources Association Conference
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• 2009.05a
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• pp.1327-1331
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• 2009

SWAT(Soil and Water Assessment Tool)은 대규모의 복잡한 유역에서 장기간에 걸친 다양한 종류의 토양과 토지이용 및 토지관리 상태에 따른 물과 유사 및 농업화학물질의 거동이 토지관리방법에 미치는 영향을 예측하기 위해 미국 농무성 농업연구소(USDA Agricultural Research Service, ARS)의 Jeff Arnold에 의해 1990년대 초에 개발된 유역모델이며, 최근에는 SWAT2005 모형이 개발되었다. SWAT 모형은 SWAT2000 모형을 구동하기 위한 ArcView 3.2a 기반의 인터페이스 시스템이 널리 이용되어 왔으나, 최근에는 SWAT2005 모형과 ArcGIS를 연계 운영하기 위한 ArcSWAT(Winchell et al, 2008)이 개발된 바 있다. 국내에서는 GIS와 데이터베이스를 기반으로 SWAT2000 모형의 구동 및 입출력 자료의 관리 등을 효과적으로 수행할 수 있는 SWAT2000 모형과 HyGIS(Hydro Geographic Information System)를 연계시스템인 HyGIS-SWAT(김경탁과 최윤석, 2006)이 개발된 바 있다. 본 연구에서는 최근 들어 SWAT2005 모형의 활용성이 높아짐에 따라 HyGIS와 SWAT2005 모형의 연계시스템을 개발하고자 하며, 이를 통해서 SWAT2005 모형 구동의 효율성과 편의성을 증대시킬 뿐만 아니라, 개선된 SWAT2005 모형으로 기존의 HyGIS-SWAT을 개선하고자 한다.

• Proceedings of the Materials Research Society of Korea Conference
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• 2011.10a
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• pp.35.2-35.2
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• 2011

In this study, hyaluronic acid (HyA) - Gelatin (Gel) hydrogels were prepared at ratio of 15:85 with the goal of obtaining a high uniform porosity and porous biocompatibility scaffold for bone tissue engineering applications. In order to develop a proper scaffold for bone implant application, a HyA-Gel hydrogel loaded in sponge Biphasic Calcium Phosphate (BCP) was prepared. To assay the cytocompatibility and cell behavior on the HyA-Gel hydrogel and HyA-Gel/BCP scaffold, cell attachment and spreading of MSCs seeded on the scaffolds were studied. An invivo study was performed for HyA-Gel/BCP scaffolds after 1 and 3 months implantation. Our results provide a novel and simple method to obtain an adequate scaffold for osteoblast cells and indicate that HyA-Gel hydrogel and HyA-Gel/BCP scaffold could be a good candidate for bone tissue engineering scaffolds.

• Journal of Environmental Impact Assessment
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• v.19 no.3
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• pp.223-230
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• 2010

Trajectory dispersion models are used for the dispersion calculations in air quality assessments, Yellow-sand modeling, environmental planning and the emergency response. Meso-scale forcing and coastal circulations are calculated by trajectory model in the East Asia region. In this study the meteorological fields (GDAS and MM5) coupled to the trajectory model (HY-SPLIT) are applied to simulate the transport and the dispersion. Seoul is selected as a starting point of the HY-SPLIT. The sensitivity studies are performed by conducting an ensemble of simulations using the GDAS and the MM5 model for the same dispersion cases. The results in this study show a significant difference depending on the resolution of meteorological models. Additionally, in most cases of the compared tionally,results from MM5 and GDAS, the absolute and relative distance, shows significant difference and the difference increased with the increasing distance of HY-SPLIT. Therefore, for the case of small domai for twi d field distefbution over complex terrai, should be used only high model temporal or spatial resolution to improve the HY-SPLIT model results.

• Proceedings of the Korea Water Resources Association Conference
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• 2006.05a
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• pp.840-845
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• 2006

본 연구는 수리.수문 모형화에서의 시공간 자료 분석기술 개발에 관한 연구로서, 국내 GIS엔진인 GeoMania를 기반으로 하여 개발된 HyGIS와 수리.수문 연계모형을 확립하였으며, 주요 연구 결과로, 현재 국내에서 가장 보편적이고 광범위하게 적용되고 있는 HEC-HMS 모형과 HEC-RAS 모형을 선정하여 사용자의 편의성을 도모하고, 모형의 입 출력 구조, GIS와의 연계방안 등을 분석하여 제시하였다. 또한 HyGIS-HMS 모형과 HEC-RAS 모형의 개발은 국내 GIS엔진인 GeoMania-Pro와 Add-ON 방식으로 연계되어 구동되며, 입력자료는 GeoMania-Pro 프로그램 상에서 GUI에 의한 대화식으로 구성되었다. 하나의 시스템 상에서 DEM의 구축과 종합적인 유역분석 및 체계적인 하천에 대한 지형학적 자료구축과정을 제시하였고, 국내 하천유역 및 하도망의 Geo DB와 연계되는 시스템으로 구성하였다. Thiessen 계수 계산 결과에 신뢰성을 제고하였고, CN값 구성과정은 국내 유역상황과 자료구축과정에 적합하도록 개발하였다. 또한, GRID를 이용한 하천에 대한 지형학적 자료구축 과정에 있어 보다 정확한 계산이 가능하도록 구성되었고, HyGIS-HMS 모형 및 HyGIS-RAS 모형에 대한 입력자료의 구성이 편리하도록 GUI를 이용한 입력자료 구성 모듈이 적용되었고, 이러한 입력자료가 파일로 구성이 되어 각 모형에 적용될 수 있는 형태로 구성되었다. 본 연구는 HEC-HMS 및 HEC-RAS를 이용한 HyGIS-HMS 모형과 HyGIS-RAS 모형을 개발함로써 국내유역에 대한 수리 수문 모델링시 사용자들이 하나의 GIS 엔진상에서 필요한 제반사항을 모두 구현할 수 있도록 구성되어, 엔지니어링 회사, 수자원기술자, 수자원관련 연구자들에 의해서 활용될 수 있을 것이다.이 보다 향상될 것이다.>에서 $0.0190m^3/s$로, 갈수량$(Q_{355})$은 $0.0176m^3/s$에서 $0.0189m^3/s$로 약 7%가 증가하는 것으로 분석되었다. 결과로부터 침투 트렌치는 저수량 및 갈수량을 증가시키는 보조수단이 될 수 있다.해 보았다. 뿐만 아니라 이와 관련된 수문요소기술을 확보할 수 있을 것이다.역의 물순환 과정을 보다 명확히 규명하고자 노력하였다.으로 추정되었다.면으로의 월류량을 산정하고 유입된 지표유량에 대해서 배수시스템에서의 흐름해석을 수행하였다. 그리고, 침수해석을 위해서는 2차원 침수해석을 위한 DEM기반 침수해석모형을 개발하였고, 건물의 영향을 고려할 수 있도록 구성하였다. 본 연구결과 지표류 유출 해석의 물리적 특성을 잘 반영하며, 도시지역의 복잡한 배수시스템 해석모형과 지표범람 모형을 통합한 모형 개발로 인해 더욱 정교한 도시지역에서의 홍수 범람 해석을 실시할 수 있을 것으로 판단된다. 본 모형의 개발로 침수상황의 시간별 진행과정을 분석함으로써 도시홍수에 대한 침수위험 지점 파악 및 주민대피지도 구축 등에 활용될 수 있을 것으로 판단된다. 있을 것으로 판단되었다.4일간의 기상변화가 자발성 기흉 발생에 영향을 미친다고 추론할 수 있었다. 향후 본 연구에서 추론된 기상변화와 기흉 발생과의 인과관계를 확인하고 좀 더 구체화하기 위한 연구가 필요할 것이다.게 이루어질 수 있을 것으로 기대된다.는 초과수익률이 상승하지만, 이후로는 감소하므로, 반전거래전략을 활용하는 경우 주식투자기간은 24개월이하의 중단기가 적합함을 발견하였다. 이상의 행태적 측면과 투자성과측면의 실증결과를 통하여 한국주식시장에 있어서 시장수익률을 평균적으로 초과할 수 있는 거래전략은 존재하므로 이러한 전략을

• Journal of Life Science
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• v.17 no.8 s.88
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• pp.1034-1038
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• 2007

Hypericin (HyH) is a substance which is isolated a medicinal herb, Hypericum perforatum L., commonly known as St. John's Wort. Hypericum erectum is a long-lived herb that is distributed in Korea. Cloned HyH genes H. erectum of were conformed by sequencing. The cDNA Hyp-1 sequence has 732 bp with an open reading frame of 567. Thus coding for a protein of 152 amino acid residues. A BLAST re-search using the deduced nucleotide sequences in HyH gene produced significant alignments with the H. perforatum. Sequences in HyH gene showed significant homology with Rubus idaeus putative allergen Rub-i-1 mRNA, Protein sequence comparisons revealed significant homology between Hyp-1 and the phenolic oxidative coupling protein hyp-1 of H. perforatum (98%). Additionally, Hyp-1 showed sig-nificant homology with various other classes of allergens, including Pru-av-1 (62%) from Prunus avium and allergen Bet-vl-Sc3 from Betula pendula (60%). Thus, the result of this study may offer an important information to establish an assay system for chemicals of the herbal medicines for H. erectum as well as H. perforatum.

• Microbiology and Biotechnology Letters
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• v.22 no.5
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• pp.467-476
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• 1994

Lactobacillus casei HY 2782, prophage cured strain was characterized to be stable as much as L casei YIT 9018, parent strain. By southern hybridization, it was confirmed that the temperate phage was incorporated in chromosomal DNA of L. casei YIT 9018 as a prophage. It was also proved that the prophage was cured from chromosomal DNA of L casei HY 2782. The growth rate, lactic acid producing ability, carbohydrates fermentation, and enzymatic activity of L. casei HY 2782 were found to be similar to those of L. casei YIT 9018. When L casei HY 2782 was used as a host, the multiplicity of infection (M.O.I.) of the temperate phage for L. casei HY 2782 was 1.0~5.0. Restriction enzyme analysis of pLC90 plasmid from L. casei HY 2782 was shown that the size was an approximately 68.22 kb. The plasmid profiles, genomic DNA patterns, and cellular fatty acids composition of L. casei HY 2782 were similar to those of L casei YIT 9018. And the major fatty acids composition of these strains were C$_{14;0}$,C$_{16;1}$, C$_{16;0}$, C$_{18;1}$ and C$_{19;cyclo-}$ 10 sets of arbitrary primer in the PCR were screened to find differentiation against two strains of L. casei. Among them, b$_{5}-1/17-1 primer was produced an approximately 1.3 kb DNA band of only L casei YIT 9018. And b$_{5}-2/17-2 primer was produced an approximately 1.0 kb DNA band of only L casei HY 2782.

• Microbiology and Biotechnology Letters
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• v.21 no.3
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• pp.288-292
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• 1993

An agar medium(HY) was developed to detect the urease-producing lactic acid bacteria. HY medium was prepared with the addition of tryptone, glucose and tween 80 to the supernatant of autoclaved skim milk and yeast extract mixture. There was no difference in eumeration of lactic acid bacteria between the HY and commercial media, such as M17, MRS and BCP agar. The urease activity of Streptococcus salivarius subsp. thermophilus was detected on the HY agar medium contained urea by the color change of bromocresol purple as the pH indicator, but not on the commerical agar media. Furthermore, it was succeeded to screen the urease activity of bacteria in skim milk used as a raw material in dairy product manufacture. Therefore, HY medium was proved to be suitable for the screening of urease-producing lactic acid bacteria.