• Journal of Electrical Engineering and Technology
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• 제7권1호
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• pp.109-114
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• 2012

In this paper, we utilize training strategy of hidden Markov model (HMM) to use in versatile issues such as classification of time-series sequential data such as electric transient disturbance problem in power system. For this, an automatic means of optimizing HMMs would be highly desirable, but it raises important issues: model interpretation and complexity control. With this in mind, we explore the possibility of using genetic algorithm (GA) and harmony search (HS) algorithm for optimizing the HMM. GA is flexible to allow incorporating other methods, such as Baum-Welch, within their cycle. Furthermore, operators that alter the structure of HMMs can be designed to simple structures. HS algorithm with parameter-setting free technique is proper for optimizing the parameters of HMM. HS algorithm is flexible so as to allow the elimination of requiring tedious parameter assigning efforts. In this paper, a sequential data analysis simulation is illustrated, and the optimized-HMMs are evaluated. The optimized HMM was capable of classifying a sequential data set for testing compared with the normal HMM.

• Tribology and Lubricants
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• 제39권4호
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• pp.139-147
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• 2023

Cavitation phenomena observed during the operation of a submerged plain journal bearing (PJB) can affect bearing performance parameters such as dynamic coefficients, whirl frequency ratio, and critical mass. This study presents numerical solutions of the Reynolds equation for steadily and dynamically loaded submerged PJBs with half-Sommerfeld (HS), Reynolds, and Jakobsson-Floberg-Olsson (JFO) cavitation models when the supply pressure is larger or equal to the cavitation pressure. The loads at various eccentricity ratios are identical; however, the attitude angle is approximately 6% smaller when the eccentricity ratio is between 0.2 and 0.7 and the JFO model is used, compared to that when the Reynolds model is used. Dynamic coefficients obtained with the HS and Reynolds model show good agreement with each other, except for k_xz, which is sensitive to changes in the force normal to the rotor weight, and is attributed to the difference in the attitude angle obtained with each cavitation model. Stiffness coefficients are determined using the pressure distribution in the film, and therefore, when the JFO model is used, the direct stiffness coefficients are affected and show opposite signs for most eccentricity ratios. The mass-conservative JFO model can predict at least a 30% smaller critical mass compared to that using the HS and Reynolds models. Thus, the instability analysis results can change based on the cavitation model used in a submerged PJB. The results of this research indicate that the JFO model should be used when designing a rotor system supported by submerged PJBs.

• 한국음향학회지
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• 제7권2호
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• pp.20-25
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• 1988

본 연구는 소음전파에 대한 옥외실험과 축적 음향모형실험에 의해서 지표면에 의한 초과감쇠 특징을 밝힌 것으로써, 옥외실험에 의한 소음전파감쇠는 음향출력이 큰 소형엔진을 사용하여, 거리감쇠로부터 산출한 실측의 초과감쇠와 Log(D/(Hs+Hr))의 관계를 확인했다. 그 결과 소음전파감쇠는 풍향, 주파수에 따라 다르며 직선회귀 된다는 것을 알 수 있었다. 그리고, 지표면상의 초과감쇠치는 통기저항을 이용해서 Log(D/Hs+Hr))을 파라미터로써 구할 수 있었고, 가장 적당한 통기저항$\sigma$는 실측의 초과감쇠치와 임의의 $\sigma$에 대한 $L=-20Log\mid1+(r_1/r_2)Qexp(ik, \bigtriangleup r)\mid$ 식의 평균자승 오차가 가장 적어질 때 결정된다. 모형의 지표로써 축척 1/40의 모형실험으로, 큰 무향실내에서 거리감쇠의 측정을 한 결과, 실측치와의 대응이 충분하다는 것을 확인했다.

• 대한임상검사과학회지
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• 제53권4호
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• pp.342-352
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• 2021

제7기 국민건강영양조사 자료(2016~2018)를 이용해서 고감도 C반응성 단백(hsCRP)과 요산의 비만에 대한 위험도와 상호 작용이 있는지 알아보고자 하였다. 비만은 체질량지수(BMI)가 25 kg/m² 이상으로, 중증 비만은 BMI가 30 kg/m² 이상으로, 병적 비만은 BMI가 35 kg/m² 이상으로 정의하였다. 복합표본 다중 로지스틱 회귀분석에서 주요한 위험인자를 추가하여 보정하였음에도 불구하고 고농도의 hsCRP와 고농도의 요산이 동시에 존재하는 그룹은 기준 그룹보다 비만의 오즈비(odds ratio, OR)가 모든 단계에서 높았다(비만, OR 1.89, P<0.001 vs. 심한 비만, OR 5.04, P<0.001 vs. 병적인 비만, OR 8.20, P<0.001). 비만의 단계가 높아질수록 비만에 대한 hsCRP와 요산의 오즈비가 1.89에서 8.20으로 높아졌다, 이는 BMI가 증가된 참가자일수록 hsCRP와 요산의 관련성이 크다는 것을 암시한다. 더욱이, 복합표본 일반선형분석에서 주요한 교란 요인을 보정한 후 비만에 대한 hsCRP와 요산 사이의 상호 작용이 분석되었다(P for interaction=0.009).

• 정보처리학회논문지A
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• 제13A권1호
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• pp.19-26
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• 2006

진단도는 상호연결망의 신뢰도를 측정하는 중요한 요소 중 하나이다. 고장 노드를 진단하기 위한 대표적인 모델로 PMC 모델과 비교진단 모델이 있다. 본 논문에서는 두 모델을 이용하여 정규연결망 하이퍼-스타 HS(2n,n)의 진단도(Diagnosability)가 n임을 보인다.

• IMMUNE NETWORK
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• 제12권6호
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• pp.291-295
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• 2012

We previously reported that Hydnocarpi Semen (HS) has a wound healing effect on diabetic foot ulcer lesion in mice. In this study, ethylacetate (EtOAc) fraction from HS extract were evaluated for their wound healing activity by using in vitro acute inflammation model. GC and GC/MS analysis shows that the main constituents in EtOAc fraction are chaulmoogric acid, hydnocarpic acid, and gorlic acid. EtOAc fraction activated macrophages to increase the production of TNF-${\alpha}$. The fraction also increased the production of TGF-${\beta}$ and VEGF, which induced fibroblast activation and angiogenesis. These results suggest that the mechanism that the fraction helps to enhance healing of skin wound is possibly associated with the production of TNF-${\alpha}$, as well as secretion of VEGF, TGF-${\beta}$ and HS may have a new bioactive material for the treatment of skin wound.

• Journal of Ginseng Research
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• 제47권5호
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• pp.654-661
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• 2023

Background: Ginseng has been used as a traditional medicine and functional cosmetic ingredients for many years. Recent studies have focused on the potential biological effects of the ginseng berry and its ingredients. (+)-Syringaresinol (SYR) is enriched in ginseng berry and its beneficial effects on the skin have been recently reported. However, little is known about the its effects on the wound healing process of skin. Methods: Here, we evaluated the skin wound healing effect of (+)-SYR using the human fibroblast Hs68 cell and ex vivo pig and human skin tissue model. Scratch wound test and hydrogen peroxide (HPO) induce chemical wound model were employed. Results: (+)-SYR promoted the migration and proliferation of Hs68 cells without significant cytotoxicity at the tested concentrations. Especially, in ex vivo pig and human skin tissue, HPO-induced chemical wound was recovered almost completely by (+)-SYR. In line with the finding in Hs68, the protein expression levels of TGF-β and PCNA, a proliferation marker were increased, demonstrating the beneficial effects of (+)-SYR on skin wound repair. Conclusion: Collectively, we demonstrated that (+)-SYR from ginseng berry, can enhance the wound healing effect by accelerating cell proliferation and skin regeneration, suggesting the potential utility of (+)-SYR for skin wound repair.

• Structural Engineering and Mechanics
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• 제50권3호
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• pp.323-347
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• 2014

This paper proposes a Particle Swarm Optimization (PSO) algorithm, which is improved by making use of the Harmony Search (HS) approach and called HS-PSO algorithm. A computer code is developed for optimal sizing design of non-linear steel frames with various semi-rigid and rigid beam-to-column connections based on the HS-PSO algorithm. The developed code selects suitable sections for beams and columns, from a standard set of steel sections such as American Institute of Steel Construction (AISC) wide-flange W-shapes, such that the minimum total cost, which comprises total member plus connection costs, is obtained. Stress and displacement constraints of AISC-LRFD code together with the size constraints are imposed on the frame in the optimal design procedure. The nonlinear moment-rotation behavior of connections is modeled using the Frye-Morris polynomial model. Moreover, the P-${\Delta}$ effects of beam-column members are taken into account in the non-linear structural analysis. Three benchmark design examples with several types of connections are presented and the results are compared with those of standard PSO and of other researches as well. The comparison shows that the proposed HS-PSO algorithm performs better both than the PSO and the Big Bang-Big Crunch (BB-BC) methods.

• The Korean Journal of Physiology and Pharmacology
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• 제23권4호
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• pp.263-270
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• 2019

Hydrogen sulfide is well-known to exhibit anti-inflammatory and cytoprotective activities, and also has protective effects in the liver. This study aimed to examine the protective effect of hydrogen sulfide in rats with hepatic encephalopathy, which was induced by mild bile duct ligation. In this rat model, bile ducts were mildly ligated for 26 days. Rats were treated for the final 5 days with sodium hydrosulfide (NaHS). NaHS ($25{\mu}mol/kg$), 0.5% sodium carboxymethyl cellulose, or silymarin (100 mg/kg) was administered intraperitoneally once per day for 5 consecutive days. Mild bile duct ligation caused hepatotoxicity and inflammation in rats. Intraperitoneal NaHS administration reduced levels of aspartate aminotransferase and alanine aminotransferase, which are indicators of liver disease, compared to levels in the control mild bile duct ligation group. Levels of ammonia, a major causative factor of hepatic encephalopathy, were also significantly decreased. Malondialdehyde, myeloperoxidase, catalase, and tumor necrosis factor-${\alpha}$ levels were measured to confirm antioxidative and anti-inflammatory effects. N-Methyl-D-aspartic acid (NMDA) receptors with neurotoxic activity were assessed for subunit NMDA receptor subtype 2B. Based on these data, NaHS is suggested to exhibit hepatoprotective effects and guard against neurotoxicity through antioxidant and anti-inflammatory actions.

• 한국수자원학회:학술대회논문집
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• 한국수자원학회 2019년도 학술발표회
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• pp.388-388
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• 2019

하도 홍수추적의 방법은 크게 수리학적 방법과 수문학적 방법으로 구분할 수 있다. 수리학적 홍수추적 방법은 정확하지만 대량의 자료가 필요하고 시간이 오래 걸린다. 이와 반대로 수문학적 홍수추적 방법은 정확성은 떨어지지만 소량의 자료만 있으면 되고 시간이 적게 걸린다. 여러 수문학적 홍수추적에 관한 연구들이 있으며 대표적으로 Muskingum 방법이 있다. Muskingum 방법 중 Linear Muskingum Model(LMM)은 방정식의 구조적 한계 때문에 정확한 홍수추적이 어려웠고, 이를 개선하기위하여 Nonlinear Muskingum Model(NLMM), Nonlinear Muskingum Model Incorporation Lateral Flow(NLMM-L) 및 Advanced Nonlinear Muskingum Model Incorporating Lateral Flow(ANLMM-L)이 제안되었다. 본 연구는 수문학적 홍수추적 중 Muskingum 방법의 결과 차이가 어떤 요인으로 인해 발생하는지 검토하였다. 최적화 알고리즘으로 화음탐색법(Harmony Search, HS)을 사용하였으며 LMM, NLMM, NLMM-L 및 ANLMM-L의 매개변수를 산정하였다. 각 방법에 적용 시 HS의 매개변수에 변화를 주어 민감도 분석을 실시하였으며, 분석을 위한 홍수자료는 The Willson Flood data (1947)를 선택하였다. 오차비교방법은 Sum of Squares(SSQ), Root Mean Square Errors(RMSE), Nash-Sutcliffe Efficiency(NSE)를 비교하였다. 비교 결과 알고리즘의 성능에 의한 차이보다 홍수추적 방법의 차이가 더 영향이 큰 것으로 나타났다.