• 동의신경정신과학회지
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• 제23권3호
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• pp.11-22
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• 2012

Objectives : The purpose of this study is to show the differences of mental stress measured with heart rate variability (HRV) and to evaluate the effects of Aromatherapy under mental stress, according to the depression index. Methods : The volunteers were allocated into 2 groups by BDI scores. Each group is divided into 2 subgroups again. After instrumentation and 10-minutes rest period, mental stress by operation was provided for 15-minutes. HRV was recorded before and after the mental stress. Then the control groups rested for 15-minutes. The experimental groups were treated with Aromatherapy. And then HRV was recorded. Results : 1. There were no significant differences in the mean HRT and SDNN between each group. 2. LF, HF, and LF norm showed different changes in each group. 3. LF/HF ratio showed significant changes. Conclusions : These results suggest that psychic factor makes an important rule under the mental stress and the effect of Aromatherapy, and Aromatherapy is effective to recover mental stress.

• 대한한의진단학회지
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• 제11권2호
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• pp.84-95
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• 2007

Background and Purpose: We have studied the trends of EEG signals in the voluntary breathing condition by applying the fractal analysis. According to chaos theory, irregularity of EEG signals can result from low dimensional deterministic chaos. A principal parameter to quantify the degree of Chaotic nonlinear dynamics is correlation dimension. The aim of this study was to analyze correlation between the correlation dimension of EEG and HRV(heart rate variability). We have studied the trends of EEG signals in the voluntary breathing condition by applying the fractal analysis. Methods: EEG raw data were measured by moving windows during 15 minutes. Then, the correlation dimension(D2) was calculated by each 40-seconds-segment in 15 minutes data, totally 36 segments. 8 channels EEG study on the Fp, F, T, P was carried out in 30 subjects. Results and Conclusion: Correlation analysis of HRV was calculated with deterministic non-linear data and stochastic non-linear data. 1. Ch1(Fp1), Ch4(F3), Ch4(F4) is positive correlated with In LF. 2. Ch1(Fp1), Ch3(F3) is positive correlated with In TF.

• 대한전기학회:학술대회논문집
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• 대한전기학회 2008년도 제39회 하계학술대회
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• pp.2007-2009
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• 2008

본 논문에서는 인체에 열을 가했을 때 심전도(ECG) 신호에서 얻어진 Heart Rate Variability(HRV)와 광전용적맥파(PPG)에서 얻어진 Photoplethymograph Variability(PV)의 상관관계를 보기 위하여 피실험자가 상온에서 누워 있을때와 65$^{\circ}C$의 온도로 누워있을때의 심전도와 PPG를 측정하여 두 파라메터의 상관관계를 분석하여 그 효용성을 평가하였다. 이를 위하여 우선 신체 건강한 26세에서 32세까지 총 3명의 남성을 대상으로 하여 ECG와 PPG를 위와 같은 조건에서 측정한 다음, 두 신호로부터 피크를 검출하고, 피크 간격을 시계열 신호로 변환하여 HRV와 PV신호를 얻어 내었다. 또한 얻어진 HRV신호와 PV신호의 주파수 분석을 통하여 HF 및 LF성분을 비교하여 HRV와 PV의 상관관계를 비교하였다.

• 대한임상검사과학회지
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• 제51권3호
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• pp.329-335
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• 2019

매년 호흡기 바이러스 감염으로 인해 수 백만명의 소아들이 사망한다. 호흡기 바이러스 감염의 원인 병원체 중 Human rhinovirus (HRV)는 코감기의 주요 원인 균으로 면역력이 약한 영, 유아, 노인 그리고 천식 환자에게 심각한 호흡기 감염의 원인으로 작용하는 병원체이다. 2012년 1월부터 2018년 12월까지 천안 단국대학교 병원 진단검사의학과에 호흡기 바이러스 검사가 의뢰된 호흡기 검체 9,010개의 검체를 real time reverse transcription PCR (real time RT-PCR) 방법으로 검사했다. 총 12종의 호흡기 바이러스를 real-time RT-PCR로 검출했다. 연구기간 중 평균 검출률은 21.3%이었고, HRV 양성 환자의 평균 연령은 6.5세였다. 7월의 검출률이 32.4%로 가장 높게 나타났고 2월이 8.3%로 가장 낮았다. 연령대별로 검출률을 분석해봤을 때 10세 미만의 검출률이 가장 높았다. HRV의 중복 감염률은 35.3%이고, 가장 흔한 조합은 Adenovirus와의 조합이었다. 호흡기 바이러스 감염증은 비슷한 임상 증상을 가지고 있어 빠른 진단이 이루어 져야 적절한 시기에 적절한 치료를 할 수 있다. 호흡기 바이러스 감염은 보통 면역력이 약한 어린아이와 노인에서 주로 발생하는 것으로 알려져 있다. 하지만 본 연구에서는 10세 미만에 이어 10대 환자들의 검출률이 높았다. 그리고 1,2월을 제외하고 15% 이상의 detection rate를 보였다. HRV의 감염 양상에 대한 꾸준한 연구가 필요할 것으로 사료된다.

• 동의신경정신과학회지
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• 제20권3호
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• pp.133-147
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• 2009

Objectives : This study has the object to evaluate the effect of meditation at the clinical field and to classify the profer meditation by the emotional states of patients. Methods : Thirty volunteers have been recruited using local advertisement. They devided into two groups(patient group, normal group). Emotional states and stressors (STAI, STAXI, BDI, SCL-90-R, Stress Response inventory, Life event stress) have been evaluated. After that test HRV(Heart Rate Variability) has been tested and subjects took a 5-minute rest. After that, one of meditation has been chosed and has been demonstrated for 10 minutes by practiced trainer(Autogenic Training, Fruit Imaginary Meditation, Random assignment). After 5 minutes resting time, HRV has been measured again with meditation that had been administered. Results : 1. The higher the scale of emotional index, the more sensitively react has been occured according to the meditation. 2. The rate of HRV index that means stable state is higher in Fruit Imaginary Meditation group who thought to be administered meditation well. 3. The Fruit Imaginary Meditation is more effective immediately than Autogenic Training assessed by HRV scale and VAS scale of well-administered meditation especially in patients group. 4. Subjects of Highly suffered emotional problem have more effect in Fruit Imaginary Meditation Group compared to Autogenic Training Group. Conclusions : Suitable beginner meditation course considered patient's emotional problem needs to be programmed.

• 한국지리정보학회지
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• 제2권1호
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• pp.32-44
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• 1999

본 연구의 목적은 질감을 분광정보와 함께 사용했을 때의 분류정확도의 향상을 평가하는데 있다. 먼저 부산지역의 SPOT HRV 영상에 최대우도분류를 적용하여 토지피복도를 작성하였다. 그리고 3번 파장에서 다양한 질감을 추출한 다음, 이 질감을 신파장의 형태로 분광정보에 통합하여 분류하여 질감의 사용이 분류의 정확도에 미치는 영향을 질감별로 평가하였다. 정확도 평가는 전체적인 정확도와 토지피복별 정확도로 구분하였다. 연구결과 전체적인 정확도 향상을 관측할 수 있었는데, 특히 엔트로피의 개선 효과가 우수하였다. 그리고 창의 크기는 $5{\times}5$와 $7{\times}7$이 적절한 것으로 나타났다. 그리고 질감에 따라서는 전체적인 정확도는 향상되지 않더라도 일부 토지피복의 정확도는 개선되는 것으로 나타났다. 토지피복별로는 저층건물지역, 아파트 단지. 고층건물지역, 공업지역 등 도시지역의 개선효과가 높은 것으로 나타났다.

• 한국방사선학회논문지
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• 제16권5호
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• pp.545-551
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• 2022

본 연구는 심박변이도(HRV) 신호를 통해 산출된 스트레스 측정치와 갑상선 기능 검사(TFT) 항목 간의 상관관계를 분석하였다. K 의원에 내원한 질병이 없는 건강한 성인 181명을 연구대상으로 하였다. 획득한 심박변이도(HRV) 신호를 이용하여 스트레스 저항도(SR)와 스트레스 지수(SI)를 산출하였으며 갑상선 기능검사(TFT) 항목으로는 TSH, Free T4, T3를 이용하였다. 측정된 값은 pearson 상관분석을 통해 각 항목 간의 관계를 통계 분석 하였다. 결과에서 Free T4와 스트레스 저항도(SR)는 양의 상관관계(r=0.18)를, 스트레스지수(SI)와는 음의 상관관계(r=-0.16)를 가졌음을 확인하였다. 이를 통해 갑상선 기능과 HRV 신호 간에 유의한 관계가 있음을 확인하였다.

• The Korean Journal of Physiology and Pharmacology
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• 제28권3호
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• pp.253-264
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• 2024

Chronic neuropathic pain (CNP) is a complex condition often arising from neural maladaptation after nerve injury. Understanding CNP complications involves the intricate interplay between brain-heart dynamics, assessed through quantitative electroencephalogram (qEEG) and heart rate variability (HRV). However, insights into their interaction in chronic pain are limited. Resting EEG and simultaneous electrocardiogram (lead II) of the participants were recorded for qEEG and HRV analysis. Correlations between HRV and qEEG parameters were calculated and compared with age, sex, and body mass index (BMI)-matched controls. CNP patients showed reduced HRV and significant increases in qEEG power spectral densities within delta, theta, and beta frequency ranges. A positive correlation was found between low frequency/high frequency (LF/HF) ratio in HRV analysis and theta, alpha, and beta frequency bands in qEEG among CNP patients. However, no significant correlation was observed between parasympathetic indices and theta, beta bands in qEEG within CNP group, unlike age, sex, and BMI-matched healthy controls. CNP patients display significant HRV reductions and distinctive qEEG patterns. While healthy controls exhibit significant correlations between parasympathetic HRV parameters and qEEG spectral densities, these relationships are diminished or absent in CNP individuals. LF/HF ratio, reflecting sympathovagal balance, correlates significantly with qEEG frequency bands (theta, alpha, beta), illuminating autonomic dysregulation in CNP. These findings emphasize the intricate brain-heart interplay in chronic pain, warranting further exploration.

• Journal of Acupuncture Research
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• 제23권3호
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• pp.143-153
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• 2006

Introduction : This study was designed to evaluate the effect of acupuncture on Unified Parkinson's Disease Rating Scale (UPDRS) and Heart Rate Variability (HRV) of patients with Parkinson's disease Methods: Subjects were voluntarily recruited through newspaper and internet advertisement. All the subjects were confirmed as idiopathic parkinson's disease by a neurologist. Acupuncture was applied 2 times a week for four weeks by oriental medical doctor at Kyung-hee University hospital. Acupuncture points used were GB34 and LR3. The patient's symptoms were assessed before and after 4 weeks of treatment by UPDRS and HRV. HRV was measured for 5 minutes before and after 4 weeks of treatment. Results : The results were as follows; 1. In both groups, UPDRS scores were significantly improved after 4 weeks compared to the pre-treatment 2. After 4 weeks of treatment UPDRS score differences between the two groups were insignificant 3. After 4 weeks of treatment HRV parameter scores showed statistically insignificant differences between the two groups. SDNN parameters of the Experimental group were significantly increased. Conclusion : This study suggests that acupuncture treatments can be applicable to improve symptoms in the patients with idiopathic Parkinson's disease. Further study on the acupuncture and HRV in the patients with Parkinson's disease is recommended.

• 동의신경정신과학회지
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• 제21권2호
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• pp.75-85
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• 2010

Objectives : This study was designed to evaluate the correlation between patterns of dyspepsia(acute dyspepsia, functional dyspepsia, dyspepsia with the organic disease) and autonomic nerve system dysfunction using HRV analysis. Methods : The patient group consisted of 88 patients diagnosed as a dyspepsia (Acute dyspepsia group-35 patients, Functional dyspepsia group-28 patients, Dyspepsia with the organic disease group-28 patients) who visited in the Oriental Medical Hospital of Dong-eui University from 2005.3.OO to 2008.8.OO. And the control group consisted of 33 patients diagnosed as a normal state of stomach during the same period. We checked HRV of the 4 groups over 5 minutes and compared the HRV index between groups. Results : 1. HF, LF, VLF and TP were significantly lower in the acute dyspepsia, functional dyspepsia and organic dyspepsia patient group than in the control group. 2. HF, LF, VLF and TP were higher in the acute dyspepsia patient group than in the organic dyspepsia patient group, but the differences were not statistically significant. 3. HF, LF, VLF and TP were higher in the acute dyspepsia patient group than in the functional dyspepsia patient group, but the differences were not statistically significant. 4. HF, LF, VLF and TP were lower in the functional dyspepsia patient group than in the organic dyspepsia patient group, but the differences were not statistically significant. Conclusions : Compared to the control group, all of the dyspepsia patient groups showed the tendency that the overall activity of the autonomic nervous system and the activity of sympathetic nerves decreased. Although there was no significant difference in the suppression of the autonomic nervous system, chronic dyspepsia patient group was lower than acute dyspepsia patient group, functional dyspepsia patient group was lower than the organic dyspepsia patient group in HRV.