• KIEAE Journal
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• 제7권5호
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• pp.59-64
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• 2007

Using air conditioner has been increased in home or office buildings in summer. Also various problems related to air conditioning such as disease induction happened by using air conditioner excessively and operating long. Active operation control is needed for occupant's health when air conditioner operates long. We should think ahead to acquire thermal comfort of occupants which represents psychological and physiological reaction for this operation. Research has been progressed to observe activity of autonomic nervous system by trying to quantitate change of thermal comfort. In this study, questions of the subject and change of body's autonomic nervous system were chosen to evaluate thermal comfort during operation of air conditioner for a long time. Electrocardiogram and questions of the subject which is the progress of changing TSV and CSV by occupants indoor were measured when room air conditioner is operated for a long time, and an air-conditioned adaptability of human body was evaluated by acquiring the change rate of autonomic nervous system through analyzing HRV. As a result of the evaluation, change rate of body's autonomic nervous system corresponded to votes of the subject's question generally, but was distinguished from analysis result of warm-cold sensation in a low temperature area.

• 생물정신의학
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• 제16권2호
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• pp.69-75
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• 2009

Objectives : The detrended fluctuation analysis is one of the nonlinear methods for the investigation of biological time series. It quantifies the fractal scaling properties and is known to be useful in the evaluation of long-range correlations in time series. The heart rate variability(HRV) of obstructive sleep apnea syndrome (OSAS) patients during nighttime was analyzed by detrended fluctuation analysis to assess its relationship with the severity of the symptoms. Methods : Fifty nine untreated male OSAS patients with moderate to severe symptoms(mean age=45.4${\pm}$11.7 years, apnea-hypopnea index, AHI${\geq}$15) underwent nocturnal polysomnography. Moderate(AHI=15-30, N=22) and severe(AHI>30, N=37) OSAS patients were compared for the indices derived from detrended fluctuation analysis and frequency domain analysis of HRV. Results : In the detrended fluctuation analysis, the alpha values were 0.75${\pm}$0.11 and 0.82${\pm}$0.07 for the severe and the moderate OSAS groups respectively. The difference was significant(p<.01). The alpha value had negative correlation with AHI(r=-.425, p=.001). Negative correlation coefficients were also found in the relationships between the alpha values and very low frequency(VLF)(r=-.425, p=.001), low frequency(LF)(r=-.633, p= <.001) and the LF/HF ratio(r=-.305, p=.019) respectively. LF/HF ratio(p=.005) was higher in the severe OSAS group compared to that of the moderate OSAS group. Conclusion : In this study, the detrended fluctuation analysis showed the significant difference between the two OSAS groups classified according to their severity of symptoms. The scaling exponent showed the negative correlation with AHI and indicies of frequency domain analysis. This result suggests that detrended fluctuation analysis can be helpful to estimate the severity of OSAS.

• Journal of Acupuncture Research
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• 제31권2호
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• pp.31-38
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• 2014

Objectives : The purpose of this study is to find the effectiveness of Korean medical treatment on stress caused by traffic accidents. HRV analysis and IES-R K research were used to evaluate it. Methods : We selected patients who entered the KangNam KyungHee Hospital between 28 Sep 2013 and 14 Apr 2014 and met inclusion/exclusion criteria. Before taking treatment, we took HRV and IES-R-K first to know the exact mental conditions of patients. For a week, we had taken acupuncture treatment, herb medicine treatment and physical therapy. After that, we compared patients' changes between before-treatment and after-treatment with the same examination. Results : In a period of one week, Korean medical treatment makes LF(Norm) stay within the normal range and HF(Norm) increase. But, we could not find statistical significance between two. The normal range of LF/HF ratio increased, and there was statistical significance. After treatment, the IES-R-K score tended to decrease. Statistically, korean medical treatment is useful to alleviate subjective stress by traffic accidents. Conclusions : Korean medical treatment makes the sympathetic system relax and parasympathetic system rise so it balances an autonomic nervous system. But, there is not statistical significance. Also, it gives positive effect on car accident patients' treatment in terms of easing their subjective stress. Prospective and Larger study will be necessary.

• 동의신경정신과학회지
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• 제19권3호
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• pp.35-44
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• 2008

Objective: There are many meditation methods used in clinical field. But the effect of meditation may be different to people's mind, and meditation itself. Now we investigate this subject with two different meditation methods which has been analyzed by heart rate variability. Method: We tried to check people's heart rate who educated meditation, before educated and during the meditation. The meditation was educated differently for each group. One is the auto genes traning, and the other is the imaginary meditation by thinking about eating and smelling favorite fruits. All of them are used to oriental psychiatry clinic patients. And we simultaneously conduct people's emotional state by SCL-90-R. Result: The result in Autogene traning group has significant difference in total power and HRV-index score between before and during the training but in imaginary meditation group has no significance: Autogene traning group has a significance in low frequency score and has increased tendency with increasing tendency of Heart rate index and Total power. Through the SCL-90-R score, the higher depression t-score, the anxiety t-score, and the hostility score is, the HRV scores such as total power, low frequency, and HRV-index much increase. and so on. Conclusion: We can guess that the Autogenes training has more significant effect than the imaginary meditation. And we can also guess that as the emotional problem is getting more severe, the effect of meditation would be much better. And we finally suggest that we should make a standard guideline of imaginary meditation, cause the imaginary meditation has so many variation.

• 대한한방부인과학회지
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• 제24권3호
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• pp.109-115
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• 2011

Objectives: To characterize autonomic dysfunction in patients with Cold hypersensitivity, their heart rate variability(HRV) were measured and analyzed with cold hypersensitivity patients, compared with those of normal population. Methods: We studied 56 patients visiting Gangnam Kyung-hee korean hospital from 1st January 2010 to 31th December 2010. Heart rate variability were obtained from 28 female patients who suffer from cold hypersensitivity and 28 healthy female controls in resting state. We studied the difference of Heart rate variability between two groups by Independent T-test using SPSS for windows(version 17.0). Results: Standard deviation of NN interval(SDNN), total power(TP), Very low frequency(VLF) in patients with cold hypersensitivity were significantly different with those of controls. While no significant differences were observed in square root of mean squared differences of successive NN intervals (RMSSD), low frequency (LF) and high frequency(HF). Conclusions: The decreased values of heart rate variability(HRV) study means that they may have some kinds of imbalance in autonomic nervous system in cold hypersensitivity patients. heart rate variabiliry(HRV) study might be a tool of diagnosis and predictors in cold hypersensitivity patients.

• 동의생리병리학회지
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• 제20권2호
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• pp.482-487
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• 2006

The identification of the exterior-interior pattern and the cold-heat pattern is one of the most frequently used diagnostic methods in Oriental medicine. No systematic studies, however, have yet been conducted to determine the emotional and autonomic factors involved in the exterior-interior and cold-heat. In this study, the relationships between depression, anxiety, and the exterior-interior and cold-heat patterns in 100 healthy female volunteers with a mean age of 42.77 were also investigated. The autonomic nervous system's control of human temperature is a well known fact. Thus, this paper also aimed to investigate the correlationof the autonomic nervous system and patterns of the exterior-interior and cold-heat. The analysis of heart rate variability (HRV), which has become a popular non-invasive tool for assessing the activities of the autonomic nervous system, was conducted in this study. No relationship was found between the exterior-interior and cold-heat pattern scores and the degree-of-depression scores. But there was a significant difference between the exterior-interior and cold-heat pattern scores of the different anxiety types, and between those of the different anxiety levels. The depression and anxiety levels also had an effect on the HRV indices.

• 성인간호학회지
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• 제24권2호
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• pp.139-148
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• 2012

Purpose: A study was designed to compare heart rate variability (HVR) of older adults with postprandial hypotension (PPH) with older adults with no PPH. Methods: The samples were community-dwelling older adults (${\geq}$ 60 years old) with PPH (n=35) and without PPH (n=35). HRV was measured by 10 minutes of electrocardiography using Physiolab 400 and analyzed in time domain (SDNN) and with power spectral analysis in frequency domain (TP, LF, HF, LF/HF). Blood pressure was measured every 15 minutes before and until 120 minutes after the meal. Results: All HRV parameters were lower in the PPH group compared to those with no PPH. Specifically the measures of SDNN, TP, LF, and LF/HF of the PPH group were significantly lower (U=385.0, $p$=.008; U=361.0, $p$=.003; U=375.0, $p$=.005; U=368.0, $p$=.004, respectively). Further, the LF and LF/HF of SBP (${\geq}140$ mmHg) group and the LF/HF of DBP (${\geq}$ 90 mmHg) group were significantly lower ($x^2$=6.33, $p$=.042; $x^2$=33.10, $p$ <.001; $x^2$=11.03, $p$=.004, respectively). Conclusion: These findings indicate that the autonomic nervous functions in persons with PPH are less activated than those persons with no PPH. The findings contribute to an understanding of HRV and the association of autonomic nervous function with the mechanism of PPH.

• 미생물학회지
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• 제35권3호
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• pp.226-230
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• 1999

무지개송어 등의 연어과 어류에서 발생하는 전염성 조혈기괴사증 바이러스의 국내분리주인 IHNV-PRT 의 특성을 규명하기 위하여 IHNV-PRT 의 당단백질인 G를 암호화하고 있는 유전자의 일부를 PCR로 증폭한 후 cDNA를 클로닝하여 이들의 염기서열을 분석하였다. 이 PCR product 는 442 bp의 크기이었다. IHNV-PRT 의 G의 염기서열을 IHNV 의 다른 strain 과 비교 분석한 결과 IHNV-RB-76, IHNV-RB, IHNV-LR-73, IHNV-K, IHNV-WRAC, IHNV-SRCV, IHNV-CoI-85들의 G와 각각 95,94,94,94,93,93%의 상동성을 보였다. 그러나 넙치로부터 분리된 fish rhabdovirus 인 hirame rhabdovirus 의 G와는 81%의 사동성을 보였다. 이 결과로부터 IHNV 의 G 유전자는 비록 HRV 의 G 유전자와 유사성은 높지 않지만, IHNV 의 strain 에 관계없이 유사하다는 것을 알 수 있다.

• 전기전자학회논문지
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• 제21권4호
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• pp.381-387
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• 2017

직장에서의 스트레스는 많은 직업, 생활환경 및 연령대의 사람들에게 영향을 끼치는 심각한 문제가 되었다. 스트레스 관리는 스트레스가 질병을 일으키기 시작하기 훨씬 전에 시작해야 한다. 본 연구에서는 영상 및 소음 자극 시 발생하는 전기피부반응도, 심전도 및 뇌파를 측정하여 스트레스를 평가하는 연구를 수행하였다. GRS 진폭은 스트레스 상황이 안정 상태(baseline)보다 27.9% 높게 나타났다. 그리고 자극 후 baseline의 응답시간은 스트레스 상황보다 71.6% 이상 시간이 더 길었다. 심박변이도에서 스트레스 응답 특성은 RMSSD의 변화율이 16.4% 차이가 났으며, HF power의 변화율은 29.7% 차이를 보였다. 뇌파는 스트레스 자극 시 주파수 대역이 ${\theta}$파 대역으로 점점 변함을 알 수 있었다. 우리는 영상자극 및 소음자극이 스트레스와 상관관계를 파악함으로써 객관적지표로 활용 가능할 것이다.

• 대한한방부인과학회지
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• 제30권3호
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• pp.54-64
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• 2017

Objectives: The purpose of this study is to demonstrate Heart Rate Variability characteristics of menopausal patients with insomnia. Methods: From March 1, 2014 to June 20, 2017, Heart Rate Variability was measured in 102 menopausal patients who visited Cheonan Korean Medicine Hospital of Daejeon University. We compared accompanying symptoms and Heart Rate Variability values depending on sleep quality in menopausal women. Results: The accompanying symptoms of menopausal patients were as follows: hot flushes (45.1%), tiredness (25.49%), chest discomfort and palpitations (23.53%), headache (17.65%), arthralgia and muscular pain (17.65%), cold sensitivity of hands and feet (15.69%), urinary frequency (14.71%) and anxiety (10.78%). The frequency of chest discomfort and palpitation was significantly higher in the menopausal insomnia group than in normal sleep group. Comparing Heart Rate Variability between two groups, Standard deviation of the NN interval (SDNN), Total Power (TP), and Low Frequency (LF) values were significantly lower in insomnia group. Conclusions: Chest discomfort and palpitations were more frequent in insomnia patients in menopausal women than normal sleep group, and Standard deviation of the NN interval (SDNN), Total Power (TP), Low Frequency (LF) were significantly lower in HRV values.