• Journal of Oriental Neuropsychiatry
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• v.21 no.2
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• pp.87-101
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• 2010

Objectives : The aim of this experiment was to investigate the influences of Autonomic Nervous System and EEG by conducting Reinforcement-Reduction(補瀉) acupuncture stimulation to compare the changes in acupoints on the body before and after treatment of acupuncture at Xingjian(LR2) being referred as Fire-point(火穴) and Ququan(LR8) being referred as Water-point(水穴) of Yin Liver Meridian(足厥陰肝經). Methods : This study was carried out on 30 healthy female volunteers in their 20's. There were four tests conducted throughout and the period for each test was between 2 to 5days. HRV and EEG were measured for 5 minutes before acupuncture stimulation was conducted on LR2-Reinforcement, LR2-Reduction, LR8-Reinforcement and LR8-Reduction at random. During the 20 minutes of acupuncture treatment, same subjects were measured simultaneously to observe any significant changes in acupoints. Again, the same subjects were measured for 5 minutes after removing the acupuncture in order to perform a comparative analysis. Results : The measurement of HRV showed that LF, LFnorm and LF/HF ratio increased significantly(p<0.05) while HF, HF norm decreased significantly in case of LR2-Reinforcement & LR8-Reduction. Both LR2-Reduction and LR8-Reinforcement induced a significant increase in HFnorm. EEG measurement indicated low $\alpha$ wave decreased and high $\beta$ wave increased significantly at LR2-Reinforcement during post-acupuncture period compared with acupuncture stimulation period. Both LR2-Reduction and LR8-Reinforcement developed significantly low $\alpha$ wave and high $\alpha$ wave. High $\beta$ wave increased significantly at LR8-Reduction during the acupuncture stimulation in comparison with pre-acupuncture period. Conclusions : The manipulation of acupuncture stimulation at LR2-Reinforcement and LR8-Reduction enhanced the activity of sympathetic nerves and the state of arousal while that of para sympathetic nerves declined. On the other hand, LR2-Reduction and LR8-Reinforcement developed the levels of para sympathetic nerves and relaxation.

• Journal of the Korea Safety Management & Science
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• v.11 no.4
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• pp.111-118
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• 2009

In this study the real situation of apartment house in seoul is reproduced with multi-zone modeling program CONTAM2.4. This model include disinfection system which is consist of dilution, filtration, UVGI(ultra violet germicidal irradiation). It's energy consumption was also analyzed through the linked model of CONTAM and TRNSYS according to the combination of components. The comparison of total energy consumption through energy analysis revealed that adjusting the air change rate of the UVGI air sterilizer to maintain the same indoor microbe removal capability was more advantageous in terms of energy consumption.

• The Journal of Korean Obstetrics and Gynecology
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• v.23 no.4
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• pp.155-163
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• 2010

Purpose: The aim of the study was to compare the characteristics of the autonomic innervation of the heart in polycystic ovary syndrome(PCOS) patients with regulary cycling controls. Methods: We studied 21 patients visiting $\bigcirc\bigcirc$hospital from 25th June 2009 to 25th June 2010. The subjects were categorized in two groups, 11 PCOS patients and 10 healthy regularly cycling controls. We studied the difference of Heart rate variability (HRV) between two groups by Independent samples T-test using SPSS for windows(version 17.0). Results: The Standard deviation of all normal R-R intervals (SDNN), The spuare root of the sum of the spuare of difference between adjacent normal R-R intervals (RMS-SD) of PCOS group was non-significantly lower than non-PCOS group. High frequency power (HF) and Normalized high frequency power (HF norm) of PCOS group was significantly higher than non-PCOS group. Normalized low frequency power (LF norm) of PCOS was signficantly lower than non-PCOS group. The results means increased sympathetic and decreased vagal modulation. Total power (TP), Very low frequency power (VLF) of PCOS group was non-significantly lower than non-PCOS group. Low frequency power (LF), LF/HF ratio of PCOS group was non-significantly higher than non-PCOS group. Conclusion: The results suggest that PCOS can be related to decreased activity of parasympathetic nervous system.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.14 no.11
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• pp.2435-2441
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• 2010

A global healthcare system based on M2M technology is proposed to support a good mobility, flexibility and scalability to the patients in 6LoWPAN. Sensor nodes integrated with wearable sensors are linked to gateway with IEEE 802.15.4 protocol and 6LoWPAN protocol for data acquisition and transmission purpose via external network. In the server, heart rate variability signals are obtained by signal processing and used for time and frequency domain performance analysis to evaluate the patient's health status. Our approach for global healthcare system with non-invasive and continuous IP-based communication is managed to process large amount of biomedical signals in the large scale of service range accurately.

• Journal of Oriental Neuropsychiatry
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• v.24 no.1
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• pp.45-62
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• 2013

Objectives : The purpose of this study was to compare the efficacy of Needle-Embedding Therapy with Acupuncture for Chronic Tension-type Headache (CTTH) patients. Methods : The study recruited Chronic Tension-type Headache patients. A total of twenty-six patients were divided into 2 groups. 13 subjects were placed into a needle-embedding therapy group and 13 subjects into an acupuncture therapy group by a randomization table. The needle-embedding therapy group was treated with needle-embedding at Fengchi (GB20), while the acupuncture therapy was acupunctured at Fengchi (GB20). Then, a comparative analysis was conducted by comparing the results with those measured by a Blood pressor, Heart rate variability (HRV), Henry Ford Headache Disablity Inventory (HDI) Internet Headache Impact Test (HIT), and Visual Analogue Scale (VAS). Results & Conclusions : As a result of evaluation by using the self-rating headache index (VAS, HDI, HIT), pain score declined in both groups. But they were not difference between the two groups.

• Journal of Acupuncture Research
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• v.25 no.5
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• pp.127-137
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• 2008

Objectives : These days, herbal acupuncture therapy is widely applied to many diseases and symptoms by Korean medical doctors in Korea. The aim of this study was to demonstrate the effect of Carthami-Semen herbal acupuncture(CSHA) on chronic constipation. Methods : This single-blind placebo-controlled randomized parellel study enrolled 24 adults with chronic constipation. After one week's run-in period, they were randomly assigned to receive CSHA therapy, or placebo therapy for 4 weeks by 2 times per week. After completing 4 week's therapy, 2 week's follow-up period was continued. During study, defecation frequency, consistency and ease of evacuation were checked before study, every week and follow-up periods. Also, the VAS of constipation, quality of life(QoL) and heart rate variability(HRV : low frequency, high frequency) were checked 3 times totally. Finally, 21 subjects completed the protocol and 20 subjects were analyzed.(1 subject is excluded for analysis because of not following the protocol.) Results : In CSHA group, defecation frequency(continued after 1 week), consistency and ease of evacuation(at 1 week after and follow-up) were increased significantly. The VAS of constipation in CSHA group was significantly decreased. There was no significant change at QoL and HRV. Conclusions : CSHA therapy was effective in treating adults with chronic constipation. Study that have larger case number and longer follow up will be needed in the future.

• Journal of The Korean Society of Integrative Medicine
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• v.11 no.4
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• pp.27-39
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• 2023

Purpose : The aim of this study was to identify the influence of transient isokinetic exercise on cardiac autonomic modulation and muscle properties in healthy male subjects. Methods : Twenty-eight healthy males underwent isokinetic exercise of both knee joints using a Biodex systems 3 isokinetic dynamometer with an angular velocity of 60 °/sec. The changes in activity of the autonomic nervous system, as determined by heart rate variability (HRV), and in muscle properties were evaluated at three times: pre-exercise, immediately post-exercise, and 10 min post-exercise. Results : The time domain analysis of HRV revealed significant changes in the beat count and mean and minimal heart rate (HR) measured at pre-exercise, immediately post-exercise, and 10 min post-exercise (p<.001). The beat count and mean HR were markedly increased immediately post-exercise compared to pre-exercise, but then significantly decreased at 10 min post-exercise (p<.001). All parameters of the frequency domain were significantly altered by isokinetic exercise (p<.01). The low frequency/high frequency (LF/HF) ratio, as an index for the sympathovagal balance, was elevated by exercise and remained at a similarly high level at 10 min post-exercise (p<.01). The muscle properties of rectus femoris were changed as follows: Muscle tone and stiffness were significantly increased between pre-exercise and immediately post-exercise (p<.001), and between pre-exercise and at 10 min post-exercise (p<.001). Whereas, the elasticity showed no significant change. Conclusion : These results demonstrated that transient isokinetic exercise could induce changes in cardiac autonomic control and muscle properties. In particular, up-regulation of LF/HF ratio after exercise signifies thus enhanced sympathetic modulation by isokinetic exercise. Therefore, it is needed to understand the cardiovascular risks that may arise during isokinetic exercise for providing the basic evidence to establish appropriate isokinetic exercise protocols as effective rehabilitation exercises.

• Journal of the Korean Institute of Electrical and Electronic Material Engineers
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• v.24 no.7
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• pp.605-608
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• 2011

In this study, OSA (the obstructive sleep apnea) periods were detected in patients with OSA during sleep because of the treatment was different according to the frequency and symptoms of obstructive sleep apnea. ANS (autonomic nervous activity) was changed by obstructive sleep apnea periods so we intended to detect the periods to care the obstructive sleep apnea patients. RR intervals, SDNN (standard deviation of normal to normal) and RMSSD (root mean square standard deviation) were calculated in time domain analysis and LF (low frequency), HF (high frequency), NHF (normalized high frequency), NLF (normalized low frequency) were calculated in frequency domain analysis of HRV (heart rate variability) with obstructive sleep apnea patients. In this paper, SDNN (standard deviation of normal to normal) of time domain analysis were decreased in the obstructive sleep apnea periods. And NLF and LF/HF ratio were increased and NHF (normalized high frequency) was decreased in the frequency domain analysis. The parameters can be used to treat obstructive sleep apnea patients by detecting the obstructive sleep apnea periods such as CPAP (continuous positive airway pressure).

• Korean Journal of Biological Psychiatry
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• v.28 no.1
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• pp.13-22
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• 2021

Objectives Despite growing attention to anxiety in bipolar disorder (BD), little research has assessed anxiety symptoms in the course of BD. The current prospective follow-up study examines the influence of subjectively and objectively measured anxiety symptoms on the course of BD. Methods A total of 49 patients with BD were followed-up prospectively for average of one year at an average of four months interval. The Korean version of the Beck Anxiety Inventory (K-BAI), the Hamilton Anxiety Rating Scale, heart rate variability (HRV) were used to measure anxiety subjectively, objectively and physiologically. Participants were divided into high and low anxiety groups based on their K-BAI scores. Kaplan-Meier survival analysis was performed to compare the recurrence of mood episode, suicide attempt, emergency room visit, and psychiatric hospitalization between two groups. Mediators were investigated with Cox proportional hazards models. Results Compared to the low anxiety group, the high anxiety group reported significantly higher impulsiveness (p = 0.016) and lower high frequency component on HRV (p = 0.007) after controlling for severity of BD. Regarding survival analysis, the high anxiety group showed hastened depressive episode recurrence (p = 0.048) and suicidal ideation was the mediator of the hazard ratio (HR) 1.089 (p = 0.029) in the Cox model. Moreover, the high anxiety group showed a tendency of accelerated suicide attempt (p = 0.12) and impulsivity was the risk factor of suicide attempt (HR = 1.089, p = 0.036). Conclusions This interim analysis of prospective study suggests that high anxiety level in BD may anticipate unfavorable course. Further studies are needed to understand the multifactorial mechanism of anxious bipolar patients.

• Proceedings of the KSRS Conference
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• 2004.10a
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• pp.306-309
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• 2004

The susceptibility of landslides and the effect of landslide-related factors at Penang in Malaysia using the Geographic Information System (GIS) and remote sensing data have been evaluated. Landslide locations were identified in the study area from interpretation of aerial photographs and from field surveys. Topographical and geological data and satellite images were collected, processed, and constructed into a spatial database using GIS and image processing. The factors chosen that influence landslide occurrence were: topographic slope, topographic aspect, topographic curvature and distance from drainage, all from the topographic database; lithology and distance from lineament, taken from the geologic database; land use from Landsat TM (Thermatic Mapper) satellite images; and the vegetation index value from SPOT HRV (High Resolution Visible) satellite images. Landslide hazardous areas were analysed and mapped using the landslide-occurrence factors employing the probability-frequency ratio method. To assess the effect of these factors, each factor was excluded from the analysis, and its effect verified using the landslide location data. As a result, land 'cover had relatively positive effects, and lithology had relatively negative effects on the landslide susceptibility maps in the study area. In addition, the landslide susceptibility maps using the all factors showed the relatively good results.