• 제목/요약/키워드: HRM analysis

검색결과 126건 처리시간 0.029초

Value of PAX1 Methylation Analysis by MS-HRM in the Triage of Atypical Squamous Cells of Undetermined Significance

  • Li, Shi-Rong;Wang, Zhen-Ming;Wang, Yu-Hui;Wang, Xi-Bo;Zhao, Jian-Qiang;Xue, Hai-Bin;Jiang, Fu-Guo
    • Asian Pacific Journal of Cancer Prevention
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    • 제16권14호
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    • pp.5843-5846
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    • 2015
  • Background: Detection of cervical high grade lesions in patients with atypical squamous cells of undetermined significance (ASCUS) is still a challenge. Our study tested the efficacy of the paired boxed gene 1 (PAX1) methylation analysis by methylation-sensitive high-resolution melting (MS-HRM) in the detection of high grade lesions in ASCUS and compared performance with the hybrid capture 2 (HC2) human papillomavirus (HPV) test. Materials and Methods: A total of 463 consecutive ASCUS women from primary screening were selected. Their cervical scrapings were collected and assessed by PAX1 methylation analysis (MS-HRM) and high-risk HPV-DNA test (HC2). All patients with ASCUS were admitted to colposcopy and cervical biopsies. The Chisquare test was used to test the differences of PAX1 methylation or HPV infection between groups. Results: The specificity, sensitivity, and accuracy for detecting CIN2 + lesions were: 95.6%, 82.4%, and 94.6%, respectively, for the PAX1 MS-HRM test; and 59.7%, 64.7%, and 60.0% for the HC2 HPV test. Conclusions: The PAX1 methylation analysis by MS-HRM demonstrated a better performance than the high-risk HPV-DNA test for the detection of high grade lesions (CIN2 +) in ASCUS cases. This approach could screen out the majority of low grade cases of ASCUS, and thus reduce the referral rate to colposcopy.

DNA 바코딩과 고해상 융해곡선분석에 기반한 인삼속 식물의 종 판별 (Internal Transcribed Spacer Barcoding DNA Region Coupled with High Resolution Melting Analysis for Authentication of Panax Species)

  • 방경환;김영창;임지영;김장욱;이정우;김동휘;김기홍;조익현
    • 한국약용작물학회지
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    • 제23권6호
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    • pp.439-445
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    • 2015
  • Background : Correct identification of Panax species is important to ensure food quality, safety, authenticity and health for consumers. This paper describes a high resolution melting (HRM) analysis based method using internal transcribed spacer (ITS) and 5.8S ribosomal DNA barcoding regions as target (Bar-HRM) to obtain barcoding information for the major Panax species and to identify the origin of ginseng plant. Methods and Results : A PCR-based approach, Bar-HRM was developed to discriminate among Panax species. In this study, the ITS1, ITS2, and 5.8S rDNA genes were targeted for testing, since these have been identified as suitable genes for use in the identification of Panax species. The HRM analysis generated cluster patterns that were specific and sensitive enough to detect small sequence differences among the tested Panax species. Conclusion : The results of this study show that the HRM curve analysis of the ITS regions and 5.8S rDNA sequences is a simple, quick, and reproducible method. It can simultaneously identify three Panax species and screen for variants. Thus, ITS1HRM and 5.8SHRM primer sets can be used to distinguish among Panax species.

중소기업의 경영혁신인프라와 인적자원관리 개별활동이 경영성과에 미치는 영향 (A Study on the Effect for the Management Innovation Infra and HRM Practices to Performance of Small and Medium-sized Businesses)

  • 전순영
    • 한국산학기술학회논문지
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    • 제12권11호
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    • pp.4888-4894
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    • 2011
  • 본 연구에서는 인적자원관리의 개별활동 들을 중심으로 기업의 경영혁신인프라요소들과 인적자원관리 개별 활동이 경영성과에 영향을 미치는가를 살펴보고자 한다. 각 변수들의 효과행태는 구조방정식에 의하여 분석되었으며, 경영혁신인프라요소는 모든 인적자원관리 개별활동에 정의 영향을, 인적자원관리 개별활동은 충원, 교육훈련, 보상 및 유지, 경력개발 활동이 이직률에 부의 영향을 미치는 것으로 분석되었다.

빅데이터 기반의 인사 데이터 분석을 통한 맞춤형 HRM 시스템 설계 (Design of Personalized HRM System by HR Data Analysis Based on BigData)

  • 강민영;박석천;홍석우;김태엽
    • 한국정보처리학회:학술대회논문집
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    • 한국정보처리학회 2013년도 추계학술발표대회
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    • pp.1218-1221
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    • 2013
  • 최근 기업들은 빅데이터 활용을 통해 얻은 분석결과를 고객 마케팅 및 영업 전략 수립에 적극 활용함으로써 수익성 증대 및 비용 절감이라는 기대 효익를 달성하고 있다. 이러한 흐름에 따라 기업 내 시스템 사용자를 고객으로 두고 있는 HRM시스템 역시 인사데이터 분석을 기반으로 사용자의 기호와 요구사항을 반영한 가치 있는 정보를 제공해줌으로써 기존 기업 고객 이외에 잠재적인 고객층을 확보할 수 있는 맞춤형 HRM 시스템으로 진화해야 할 것이다. 본 연구에서는 빅데이터 기반의 인사데이터 분석의 필요성과 국외 인사데이터 분석 활용사례를 살펴보고 이를 기반으로 빅데이터 분석기술을 활용하여 사용자에게 가치 있는 정보를 제공해주는 개인화된 맞춤형 HRM시스템을 제안 및 설계하고자 한다.

Strategic Bundling of HRM for Organizational Performance: an Empirical Study of Publicly Listed Companies

  • Gautam, Dhruba Kumar
    • 아태비즈니스연구
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    • 제5권2호
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    • pp.51-64
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    • 2014
  • Strategic bundling of Human Resource Management (HRM) practices among themselves works together as an entire HRM system rather than individual HRM practices to achieve organizational objectives. The bundles of HR practices support the effectiveness of one another assuming the effectiveness of any practice depends on other practices in place. It is said that the greater the total degree of bundling among the various components of HRM policies and practices, the more will be the organizational outcomes. Realizing these facts, this study aimed to explore the level of strategic bundling and examined the impact of such bundling on organizational performance to the publicly listed companies of Nepal. This empirical study is based on description and exploratory design for which data collected through the questionnaire based on 5-point liker scale. Total population of the study at the time of data collection are 234 organizations publicly listed in Stock Exchange of Nepal. Questionnaire is distributed to all organizations listed, response received from 105 organizations, as a unit of analysis, which is fairly good response. The study of strategic bundling of HRM practices perhaps the first study in Nepal, found that only 32 percent organizations have followed high bundling HR practices and these high bundling organizations are significantly different with low bundling organizations. Business organizations are trying to practice being close association of HRM policies and practices within them except labor relation with employee participation and business strategies. Supporting to the international literature, strategic bundling of HRM practices among themselves shows statistically significant effects on quality of product or services, labor productivity, financial performance, employee satisfaction, rate of innovation, employee commitment and market share.

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Hyper Redundant Manipulator Using Compound Three-Bar Linkages

  • Koganezawa Koichi
    • Journal of Mechanical Science and Technology
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    • 제19권spc1호
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    • pp.320-327
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    • 2005
  • A new mechanism for hyper redundant manipulator (HRM) is presented, which comprises of serially assembled compound three-bar linkages (CTL). The CTL mechanism has some unique properties. This paper presents the forward and inverse kinematics of this mechanism and shows the simulation of the HRM havig 9 CTL units. The recursive algorithm of the inverse kinematics that the author originally developed is employed. It is fast and stable ; moreover, it enables us to obtain a solution in which the end-point of the HRM is controlled by a portion of joints. It also presents the method of the dynamical analysis. There exist kinematical constraints in the proposed closed linkage mechanism. In the dynamic analysis constraints are sufficiently sustained by the constraint stabilization method that the author developed. The mechanical structure of the HRM having some CTL units that is under construction is shown.

Outcome and Antecedent of Organizational Effectiveness: Moderation Effect of Strategy

  • KIM, Boine
    • 동아시아경상학회지
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    • 제10권2호
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    • pp.1-17
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    • 2022
  • Purpose - This exploratory study analyzes the performance of the business from the HRM point of view. Analyzed the influence of HRM and organization effectiveness on business performance. Also moderating effect of the strategy is analyzed. Research design, data, and methodology - Two outcome variables are measured, non-financial performance and financial performance. Two organizational effectiveness variables are measured, job satisfaction and organizational commitment. And two HRM areas are measured, HRM practice and organizational culture. Finally, two strategies are measured as moderators, market strategy and product/service strategy. This study analyzed employees of 554 from the 7th HCCP. This study used SEM and MCFA. Result - The results of turnover intention, growth rate, and profit rate verified the influence of HRM and organizational effectiveness. Overall results showed a contrary effect of education & training system implement and participation on job satisfaction and organizational commitment. Among organizational culture, innovation and relation positively affect job satisfaction and organizational commitment. However, antecedents influencing turnover intention, growth rate, and profit rate bear no resemblance. And the MCFA result shows that strategy's group differentiation analysis is meaningful in turnover intention not in financial performance. Conclusion - Based on this study result, management suggestions for turnover intention, growth rate, profit rate, and organizational effectiveness are made. Especially, due to the company's strategy.

HRM 분석법을 이용한 패류 내 Megalocytiviruses의 검출과 유전적 분석 (Detection and Genetic Differentiation of Megalocytiviruses in Shellfish, via High-Resolution Melting (HRM) Analysis)

  • 김광일;진지웅;김영철;정현도
    • 한국수산과학회지
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    • 제47권3호
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    • pp.241-246
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    • 2014
  • Viruses in the genus Megalocytivirus have been subdivided into four subgroups. Among these subgroups 2 and 4, represented by the red sea bream iridovirus (RBIV) and the olive flounder iridovirus (FLIV), respectively, are non-exotic. subgroups 1 and 3, represented by the red sea bream iridovirus (RSIV) and the infectious spleen and kidney necrosis virus (ISKNV), respectively, have not been detected in Korea and are known as exotic. Shellfish are filter-feeders, and can thus filter and accumulate Megalocytivirus in their digestive glands, allowing us to track viral contamination in surrounding aquatic environment. In this study, we developed a high-resolution melting (HRM) analysis to differentiate among subgroups of Megalocytivirus accumulated in shellfish, and confirmed the convenience and efficiency of this method. More than two subgroups of Megalocytivirus were found in the digestive gland of a single shellfish. We classified all Megalocytivirus viruses from shellfish in Korea into subgroups 2 and 4, although proportions of subgroups were different among regions. Compared to nucleotide sequencing analysis, HRM analysis is a simple and rapid method for differentiating of Megalocytivirus subgroups.

The Impact of Human Resource Management Activities on the Compatibility and Work Results

  • NGUYEN, Duc Trung;HA, Van Dung;DANG, Truong Thanh Nhan
    • The Journal of Asian Finance, Economics and Business
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    • 제7권9호
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    • pp.621-629
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    • 2020
  • This research focuses on determining the impact of human resource management activities on the compatibility and work results of employees of Ho Chi Minh Stock Exchange (HOSE) listed companies. The paper includes five parts: introduction, literature review, research methodology, research results, and conclusion and policy implications. The data are collected from the survey of 350 listed companies in HOSE, in which 315 survey notes filled with sufficient information are used for analysis. The paper employs both qualitative method and quantitative method. Group discussion of 10 experts is for qualitative research. Quantitative method performs analysis of Statistics, Cronbach's Alpha, EFA analysis, CFA analysis and SEM model. The results of the research clearly indicate that human resource management (HRM) activities are measured through improving the ability, improving the motivation and improving the opportunity. While compatibility is measured through suitability, connection and sacrifice; whereby HRM activities of ability improvement have a positive effect on the job suitability and connection; HRM activities of motivation improvement have a positive effect on the job suitability, connection and sacrifice; and HRM activities of opportunity improvement have a positive effect on the job suitability, sacrifice and connection; Finally, the job suitability, sacrifice and connection positively affect the work results of employees.

큐브위성용 포고핀 기반 열선절단 분리장치의 열적 거동 분석 및 검증 (Numerical and Experimental Thermal Validation on Pogo-pin based Wire Cutting Mechanism for CubeSat Applications)

  • 손민영;채봉건;오현웅
    • 항공우주시스템공학회지
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    • 제17권2호
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    • pp.94-102
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    • 2023
  • 큐브위성용 태양전지판 분리장치는 열선 또는 저항소자의 발열로 나일론선을 절단하여 구조물의 구속을 해제하는 나일론선 절단방식 구속분리장치가 주로 적용되고 있다. 일반적으로 태양전지판 조립체의 발사하중을 고려한 구조해석을 수행하여 구속분리장치의 설계가 이루어지고 있으나, 발사 이후 궤도 열환경에 대한 구속분리장치의 열적 검토 및 분석사례는 전무한 실정이다. 따라서, 본 논문에서는 현재 개발중인 큐브위성 STEP Cube Lab-II에 적용되는 나일론선 절단 기반 구속분리장치의 열적 안정성 평가를 수행하고자 한다. 위성이 POD (Picosatellite Orbital Deployer)에서 사출되고 태양전지판이 전개되기까지의 분리장치 온도 분포를 검토하여 분리장치의 허용온도 범위 내에서 안정적인 구속 분리가 될 수 있도록 분리장치에 대한 궤도 열해석을 수행하였다. 또한, 열해석 결과를 기반으로 열진공시험을 수행하여 분리장치의 설계를 검증하였다.