• Title/Summary/Keyword: HR

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Investigation of the Ethanol Fermentation Characteristics of K. fragilis by Semicontinuous Culture (반 연속식 배양에 의한 효모 K. fragilis의 알콜발효 특성에 관한 연구)

  • 허병기;류장수목영일
    • KSBB Journal
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    • v.4 no.2
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    • pp.185-190
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    • 1989
  • Semicontinuous alcohol fermentation of Jerusalem Artichoke by K. fragilis CBS 1555 was performed to investigate the effect of the effective dilution rate and influent sugar concentration to the ethanol concentration and alcohol productivity at steady state. When the time interval for the replacement of fresh influent with fermentation broth was less than or equal to 1 hr, the effective dilution rate was found out to be equal to the specific growth rate. Wash out was not occurred until the effective dilution rate, 0.425 hr-1, and the maximum alcohol productivity was around 5.5 g/1·hr. In this case, the effective dilution rate was 0.25 hr-1 and the influent sugar concentration was distributed from 85 g/l to 135 g/1.

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Improvement of Drying Schedule for Domestic Red Pine Lumber (국산 소나무재 건조스케줄 개량에 관한 연구)

  • Lee, Hyoung-Woo;Kim, Kyung-Yong
    • Journal of the Korean Wood Science and Technology
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    • v.33 no.6 s.134
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    • pp.25-30
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    • 2005
  • This experiment was carried out for the improvement of drying schedules for 50 mm-thick Japanese red pine (Pinus densiflora Sieb. et Zucc.) lumber. Drying rates were analyzed comparatively after drying to 15% of final moisture content through the applications of conventional kiln drying schedule, time schedule, continuously rising temperature schedule, and drying rate schedule. As results drying rate of 50 mm-thick red pine lumber was 0.53%/hr with conventional kiln drying schedule, 0.9%/hr with time schedule, 2.29%/hr with continuously rising temperature schedule, and 1.52%/hr with drying rate schedule, respectively.

Ramie Leaf Extracts Suppresses Adipogenic Differentiation in 3T3-L1 Cells and Pig Preadipocytes

  • Lee, Joomin;Kim, Ah-Ra;Lee, Jae-Joon
    • Asian-Australasian Journal of Animal Sciences
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    • v.29 no.9
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    • pp.1338-1344
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    • 2016
  • The present study was carried out to evaluate the anti-obesity effect of different concentrations of extracts of hot air-dried ramie leaf (HR) and freeze-dried ramie leaf (FR) in 3T3-L1 cells and pig preadipocytes. To analyze the effect on cell proliferation, cells were treated with $25{\mu}g/mL$ or $100{\mu}g/mL$ HR or FR extract for 2 days. Cell differentiation was evaluated by measuring glycerol-3-phosphate dehydrogenase and lipoprotein lipase (LPL) activities and intracellular triglyceride content. Treatment with either HR or FR extracts inhibited the proliferation of 3T3-L1 cells and pig preadipocytes in a dose-dependent manner. HR extract treatment inhibited the differentiation of both cell types more effectively than FR treatment. The extent of triglyceride accumulation decreased significantly in both cells following either HR or FR treatment. Furthermore, LPL activity significantly decreased after treatment with HR or FR extract. These results indicated that HR and FR extracts may inhibit proliferation and differentiation of 3T3-L1 cells and pig preadipocytes. Further studies are needed to explore the anti-obesity effect of HR and FR extracts.

Kinetic Studies of Lactic Acid Fermentation(Part 4) -Kinetic Stuies on Continuous Cultivation- (유산균발효에 관한 동력학적연구(제4보) -연속배양에 있어서의 동력학적연구-)

  • LEE Keun-Tai;YANG Hyeun-Suk
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.15 no.3
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    • pp.179-184
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    • 1982
  • The behavior of continuous flow culture of Lartobacillus bulgricus was investigated by application of Monod's kinetic model. The parameters obtained from Monod's chemostat theory successfully predicted the behavior of the chemostat. Then, it was found that Monod's kinetics were applicable to the growth rate dependence on glucose concentration. Under steady-state condition, the maximum growth rate, saturation constant, and wash out were found to be 0.62/hr, 7.69 g/1, 0.51/hr of continuous culture. And the optimum condition for the highest cell production was 0.41/hr in dilution rate, and at that point the cell production rate was 0.178g/1 hr.

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Pharmacokinetics of Caffeine in Caffeine Sensitive and Non-Sensitive Volunteers, and in the Obses Rat and the Lean Rat (카페인 약리작용에 민감한 지원자와 둔감한 지원자 및 뚱뚱한 쥐와 마른 쥐에 대한 카페인 약물동태 비교)

  • 윤정옥;권광일
    • YAKHAK HOEJI
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    • v.37 no.4
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    • pp.341-349
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    • 1993
  • To determine the reason of individual variation of the effect of caffeine, the absorption and the disposition of caffeine were studied in caffeine sensitive and caffeine nonsensitive volunteers. And also to study the effect of obesity on caffeine pharmacokinetics, the caffeine disposition in the obese rat and in the lean rat were investigated respectively. In result the caffeine sensitive group showed a longer terminal half-life of caffeine(7.35$\pm$0.71 hr : 5.49$\pm$0.73 hr) and a larger AUC (55.42$\pm$9.09 $\mu\textrm{g}$.$ml^{-1}$.hr:44.0$\pm$7.81$\mu\textrm{g}$.$ml^{-1}$.hr) than that of caffeine non-sensitive group without statistical significance. The obese rat showed a longer terminal half-life (3.47 hr : 2.31 hr) and a larger AUC(35.3 $\mu\textrm{g}$.$ml^{-1}$.hr:26.97$\mu\textrm{g}$.$ml^{-1}$.hr) than that of the lean rat. But there was no correlation in the amount of daily caffeine consumption and obesity. In conclusion, we suggest that the individual variation of the effect of caffeine are being caused from the individual differences of caffeine susceptibility or tolerance rather than the differences of the genetic metabolic capacity or metabolic tolerance.

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Clinical Evaluation of Fuji HR-series (Fuji HR series의 임상평가)

  • Kang, Dae-Hyun;Shin, Dong-Sik;Kim, Young-Hwan;Kang, Hong-Seok;Lee, In-Ja;Huh, Joon
    • Journal of radiological science and technology
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    • v.11 no.2
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    • pp.21-26
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    • 1988
  • Newly developed orthochromatic film HR series have many different types according to high speed, high resolution and special latitude. And now authors have practiced various screen-film combinations, those were usual regular type Fuji new RX film-LT screen and orthochromatic type HR films-rare earth G3, G4 screens. As a result of the experiment, we obtained high speed with high resolution and expansion of diagnostic range on the following combinations compared with usual new RX/LT series. Those combinations were RXO-G and HR-L films to skull, HR-G films to knee joint and hand part, HR-L film to abdomen. Therefore it may be desirable to select adquate kinds of HR series films according to investigated parts.

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Effects of HR-AC Techniques and Kinesio Taping on Pain Changes in Delayed Onset Muscle Soreness (지연성근육통에 적용한 HR-AC기법과 키네시오 테이핑이 통증 변화에 미치는 영향)

  • Bae, Sea-hyun;Kim, Kyung-yoon
    • The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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    • v.26 no.2
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    • pp.1-10
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    • 2020
  • Background: This study aimed to investigate the effect of hold-relax and antagonist contraction (HR-AC) technique and Kinesio taping on pain changes in delayed-onset muscle soreness (DOMS) of 20's adults. Methods: Based on voluntary participation, 14 participants with induced-DOMS were randomly divided into control (non-treatment, n=7) and experiment group (HR-AC technique and kinesio taping, n=7). Measurement were used visual analogue scale (VAS), heart rate variability (HRV), and brain wave (alpha). There were 5 sets of the HR-AC technique application on the 5th day from the day of DOMS induction (rest for 30s between sets). Kinesio taping was applied to the same area after HR-AC. Results: The VAS showed significant changes according to the period and in the interaction between the period and the group (p<.01). HRV and alpha wave (Fp1) showed significant changes according to the period (p<.001). The analgesic effect was more rapid and continuous in the experimental group than in the control group. Conclusion: This study showed that the HR-AC technique and Kinesio taping are effective interventions for the management of pain and stress caused by DOMS.

Binary Classification of Hypertensive Retinopathy Using Deep Dense CNN Learning

  • Mostafa E.A., Ibrahim;Qaisar, Abbas
    • International Journal of Computer Science & Network Security
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    • v.22 no.12
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    • pp.98-106
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    • 2022
  • A condition of the retina known as hypertensive retinopathy (HR) is connected to high blood pressure. The severity and persistence of hypertension are directly correlated with the incidence of HR. To avoid blindness, it is essential to recognize and assess HR as soon as possible. Few computer-aided systems are currently available that can diagnose HR issues. On the other hand, those systems focused on gathering characteristics from a variety of retinopathy-related HR lesions and categorizing them using conventional machine-learning algorithms. Consequently, for limited applications, significant and complicated image processing methods are necessary. As seen in recent similar systems, the preciseness of classification is likewise lacking. To address these issues, a new CAD HR-diagnosis system employing the advanced Deep Dense CNN Learning (DD-CNN) technology is being developed to early identify HR. The HR-diagnosis system utilized a convolutional neural network that was previously trained as a feature extractor. The statistical investigation of more than 1400 retinography images is undertaken to assess the accuracy of the implemented system using several performance metrics such as specificity (SP), sensitivity (SE), area under the receiver operating curve (AUC), and accuracy (ACC). On average, we achieved a SE of 97%, ACC of 98%, SP of 99%, and AUC of 0.98. These results indicate that the proposed DD-CNN classifier is used to diagnose hypertensive retinopathy.

Improvement of Hybrid Vision Correction Algorithm for Water Resources Engineering Problem (수자원공학 문제 적용을 위한 Hybrid Vision Correction Algorithm의 개량)

  • Ryu, Yong Min;Lee, Eui Hoon
    • Proceedings of the Korea Water Resources Association Conference
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    • 2021.06a
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    • pp.196-196
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    • 2021
  • 상수관망은 많은 관을 통해 물의 수요가 있는 곳으로 물을 공급해주는 역할을 하는 사회기반 시설물이다. 상수관망 설계의 요점은 두 가지로 구분할 수 있다. 첫 번째 요점은 다양한 종류의 관배치로 인한 상수관망 설계안의 많은 경우의 수이다. 두 번째 요점은 상수관망 내 절점의 최저 요구수압 등의 제약조건이다. 두 가지 요점이 있는 상황에서 상수관망 설계비용의 최소화를 위한 상수관망 최적설계는 많은 계산이 요구된다. 많은 계산이 요구되기 때문에 상수관망 최적설계에 최적화 기법을 적용할 수 있다. 본 연구에서 상수관망 최적설계를 위해 적용된 최적화 기법은 Hybrid Rate(HR)를 개선한 Hybrid Vision Correction Algorithm(HVCA)이다. HVCA는 Vision Correction Algorithm(VCA)을 기반으로 추가적인 전역탐색을 실행하는 Centralized Global Search(CGS)의 적용 및 자가적응형 매개변수인 Hybrid Rate(HR)를 적용하여 사용성과 성능을 개량한 알고리즘이다. HVCA의 기존 HR은 선형적으로 증가하는 형태이다. 선형적으로 증가하는 HR로 인해 HVCA는 최적해 탐색과정에서 지역해에 빠지는 문제가 발생하였다. HVCA의 문제를 해결하기 위해 HR을 비선형적으로 증가하는 형태로 개량하였다. HR이 개량된 HVCA를 수자원공학 문제인 상수관망 최적설계 문제에 적용하여 결과를 비교하였다. 적용결과 HR이 개량된 HVCA가 기존의 HVCA보다 낮은 설계 비용을 나타내었다. 상수관망 최적설계 적용결과를 바탕으로 HR이 개량된 HVCA는 상수관망 최적설계 이외의 수자원공학 문제에도 적용가능할 것이다.

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Colony Counts by Different Disinfecting Processes and Operating Time for Humidifiers in an Intensive Care Unit (중환자실 내 가습기의 소독방법과 시간적 경과에 따른 균집락 수)

  • Park, Soon-Mi;Jeong, Ihn-Sook;Chang, Chul-Hun L.;Lee, Young-Soon
    • Journal of Korean Biological Nursing Science
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    • v.11 no.1
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    • pp.92-98
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    • 2009
  • Purpose: This study was aimed to investigate the colony counts by different disinfecting processes and duration of the operation for humidifiers in an intensive care unit (ICU) in Busan. Method: The four steps of disinfecting process were taken with four different humidifiers according to the use of disinfectant (1:100 $Deconex^{(R)}$ 50FF/nothing) and refilling water (tap water/distilled water). First, the colony counts using water sample from wick was conducted at 0 hr, 24 hr, and 48 hr respectively after turning on the humidifiers. Next, the colony counts using waterdrop from the outlet was done at 0 hr, 24 hr, 48 hr, and 72 hr respectively after turning on the humidifiers. Result: No colony was counted after disinfecting with 1:100 $Deconex^{(R)}$ 50FF until 72 hr after turning on the humidifiers. However, without disinfecting with $Deconex^{(R)}$ 50FF, the colony count was increased in the humidifiers from 24 hr after turning on the humidifiers. The result was the same regardless of the refilling water. Conclusion: According to the results, the study found that disinfection of humidifiers in the ICUs with 1:100 $Deconex^{(R)}$ 50FF every 72 hr is effective to remove general bacteria.

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