• Title/Summary/Keyword: HPS

Search Result 153, Processing Time 0.026 seconds

Developments in Radiation Health Science and Their Impact on Radiation Protection (방사선 보건과학의 발전과 방사선방호에 미치는 영향)

  • Chang, Si-Young;Kim, In-Gyoo
    • Journal of Radiation Protection and Research
    • /
    • v.23 no.3
    • /
    • pp.185-196
    • /
    • 1998
  • 현재의 방사선방호 원칙과 체계는 국제방사선방호위원회 (ICRP)의 권고에 기반을 두고 있 다. ICRP 의 권고는 대부분 히로시마/나카사키 원폭피해 생존자들에 대한 역학조사 및 수명 연구결과 그리고 관련 방사선생물학 연구결과를 바탕으로 전세계 5개 인구집단(일본, 미국, 푸에리토리코, 영국과 중국)에 대한 방사선위험계수의 예측 및 평가결과에 근거를 두고 있다. 이 저선량 방사선의 (확률적 영향) 위험계수는 인체피폭 방사선량과 그 영향간에는 선형 비례관계가 있으며 영향유발의 문턱값이 존재하지 않는다는 가정인 '선형 무문턱값 선량-영향 모델 (Linear No-Threshold Dose-Effect Model, 이른바 LNT 모텔)' 을 도입하여 유도된 것이다(譯者 밑줄). 그러나 이 LNT 가정의 과학적 근거와 정당성에 대한 비난이 원자력산업계나 일부 과학자들에 의해 제기된 이래, 최근에는 미국 보건물리학회 (HPS)에서 'LNT 가정이 선량과 영향의 관계를 단순화하며 낮은 선량의 위험음 과대평가한다'는 성명서를 발표하기도 했다. 이후 이에 대한 논쟁이 다시 시작되어, 1997 년에 스페인의 Sevill에서는 IAEA와 WHO의 공동주최와 UNSCEAR의 협조로 '저준위 방사선 영향에 대한 국제회의'가 개최되기도 하였으나 아직 어느 쪽에도 유리한 결론이 단정적으로 나지 않았으며, 실질적인 대안이 없는 현실에서 이 LNT 가정은 여전히 방사선방호의 철학적 기초로 남아 있다(譯者 밑줄). 한편, 저선량 방사선의 영향에 대해서는 우리나라에서도 '방사선방어학회, ‘98 년 춘계 심포지움' 및 '원자력학회, '98 년 춘계 학술발표회 워크??????'에서 한양대학교의 이재기 교수에 의하여 소개, 논의된 바 있다.이 논문은 이러한 논의의 후속으로 역자중 일인이 위원으로 있는 OECD/NEA 방사선방호위원회 (CRPPH)가 최근에 ('98.7.) 발간한 보고서를 번역, 주해한 것으로, 과학지식의 진보에 따라 방사선방호분야에서 관심이 되는 주제들에 대한 위원회의 검토의견을 소개하고 있다. 따라서 이 논문이 국내의 방사선방호분야 관계자들에게 최신정보 습득과 지식함양에 좋은 도움이 되기를 기대한다.

  • PDF

Optical, Mechanical and Tribological Properties of Boronnitride Dispersed Silicon Nitride Ceramics

  • Joshi, Bhupendra;Fu, Zhengyi;Niihara, Koichi;Lee, Soo-Wohn
    • Korean Journal of Materials Research
    • /
    • v.20 no.8
    • /
    • pp.444-449
    • /
    • 2010
  • Transparent ceramics are used in new technology because of their excellent mechanical properties over glasses. Transparent ceramics are nowadays widely used in armor, laser windows, and in high temperature applications. Silicon nitride ceramics have excellent mechanical properties and if transparent silicon nitride is fabricated, it can be widely used. h-BN has a lubricating property and is ductile. Therefore, adding h-BN to silicon nitride ceramics gives a lubricating property and is also machinable. Translucent silicon nitride was fabricated by hot-press sintering (HPS) and 57% transmittance was observed in the near infrared region. A higher wt. % of h-BN in silicon nitride ceramics does not favor transparency. The optical, mechanical, and tribological properties of BN dispersed polycrystalline $Si_3N_4$ ceramics were affected by the density, ${\alpha}:{\beta}$-phase ratio, and content of h-BN in sintered ceramics. The hot pressed samples were prepared from the mixture of $\alpha-Si_3N_4$, AlN, MgO, and h-BN at $1850^{\circ}C$. The composite contained from 0.25 to 2 wt. % BN powder with sintering aids (9% AlN + 3% MgO). A maximum transmittance of 57% was achieved for the 0.25 wt. % BN doped $Si_3N_4$ ceramics. Fracture toughness increased and wear volume and the friction coefficient decreased with an increase in BN content. The properties such as transmittance, density, hardness, and flexural strength decreased with an increase in content of h-BN in silicon nitride ceramics.

Implementation and Evaluation of a Health Promoting School Program (건강증진학교 수행 및 효과평가)

  • Lee, Eun-Young;Choi, Bo-Youl;Shin, Young-Jeon;Kim, Seok-Hyeon;Sohn, Ae-Ree;Ahn, Dong-Hyun
    • Korean Journal of Health Education and Promotion
    • /
    • v.26 no.2
    • /
    • pp.87-101
    • /
    • 2009
  • Objectives: The purpose of this study was to develop strategies for creating health promoting school and to evaluate the implementation and its effect on the school. Methods: Based on WHO's Health Promoting School, we developed 5 strategies and implementing process for creating health promoting school and undertook The implementation process included workshops to raise awareness of the health promoting school, establishment of a school health team, review of the health needs of its community, development of an action plan, and practice of activities and reflect on program. Seventeen teachers (male 35.3%, female 64.7%) and 248 students (male 51.2%, female 47,6%) had completed pretest and posttest. Results: It was increasing in school's social environment, community relationship, personal skill and health service among components of HPS. However, there were no significant differences in self-reported health status and health behaviors among teachers. Although there were no significant changes in self-esteem, self-efficacy and BMI, there were significantly increasing in health knowledge, physical activities and fruit and vegetable intakes among students of a pilot school. Conclusion: Strategies for a creating health promoting school were appropriate to implement in school and they would also make a contribution to improve health knowledge and health behaviors in elementary school students.

A Study on Design and Performance Evaluation of the Frequency Snthesizer Using the DDS in the Transmitter of the FFH/BFSK System (FFH/BFSK 시스템 송신부에서 DDS를 이용한 주파수합성기 설계 및 성능평가에 관한 연구)

  • 이두석;유형렬;정지원;조형래;김기문
    • Proceedings of the Korean Institute of Information and Commucation Sciences Conference
    • /
    • 1999.11a
    • /
    • pp.161-166
    • /
    • 1999
  • The global trends of mobile communication system is moving toward digitizing, high-speed and large-capacity. Also, to utilize the limited frequency-resource efficiently, spread spectrum system is a mainstream. In this study we are concerning with the fast frequency-hopping system. Instead of the PLL with many problems such as phase-noise, we used the DDS is popular in these days minimizes the disadvantage of PLL. In the case the FFH system is designed using the PLL, it is difficult to be satisfied of the design conditions such as RF badwidth and the settling time of PLL, and it has limitation because of complex circuit by using the balanced modulator. In this study, we evaluated the performance in order to design the FFH system using the DDS. The system that has the improvement of error rate, 1Mhps hopping rate and 5MHz RF bandwidth is designed and evaluated.

  • PDF

Molecular Characterization of Hantavirus Isolates from Bandicota indica Captured in Indonesia and Thailand (인도네시아와 태국의 Bandicota indica 폐장조직에서 분리된 한타바이러스의 분자생물학적 특징)

  • Chu, Yong-Kyu;Cui, Longzhu;Song, Dae-Yong;Woo, Young-Dae;Praseno, Praseno;Leitmeyer, Katrin;Lee, Ho-Wang
    • The Journal of Korean Society of Virology
    • /
    • v.30 no.3
    • /
    • pp.203-210
    • /
    • 2000
  • Hantaviruses are etiologic agents of hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS) in the world. Various hantaviruses were isolated from HFRS patients and several different rodent species in the world. Four hantavirus isolates from Indonesia and three isolates from Thailand among 89 Bandicotas captured in Yogyakarta, east region of Sumatra island, Indonesia and at Chiang Mai in Thailand during 1996 were made through several passages in Vero E6 cells. Viral genome M segment from two Indonesian isolates and three Thailand isolates were amplified using hantavirus generic primers of the M segment and cloned into pCRII vector. The genetic differences were analyzed by comparison of partial sequence of the M segment and antigenic differences were made by IFA. Nucleotide sequence homology of two isolates BC 8, BC 34 from Indonesia and two isolates thai 1322, thai 1330 to Seoul virus was 99% and 96%, respectively, but Thai 1164 was 80%Thai 1164 strain has shown 95% homology to Thai 749 virus. In conclusion it is indicated that two different serotype hantaviruses, Seoul and Thailand, are cocirculating among Bandicota in Thailand, in contrast Seoul serotype virus is circulating in Indonesia.

  • PDF

Economic Crisis and the Lowest-Low Fertility (경제위기와 저출산)

  • Lee, Sung-Yong
    • Korea journal of population studies
    • /
    • v.29 no.3
    • /
    • pp.111-137
    • /
    • 2006
  • The purpose of this study is to analyze how to change the fertility behavior at each parity after/before the economic crisis, and to find its significant determinants. The study assumes that because the socioeconomic changes have significant effects on the individual's fertility behavior, the individual's fertility behaviors and the determinants affecting fertility at each parity may change with economic crisis. Such assumption has been proven in this study. After the economic crisis, Korean fertility behavior at each parity has changed. The proportion of women having no child has increased. However, women who want to have a second child or a third one are more likely to do so within shorter period after marriage. The rectangularization of fertility has appeared after the economic crisis, because women married at later ages tends to finish their child bearing within the short period, especially before age 35. Based on the multiple variable analysis, the determinants affecting the fertility behavior have changed after the economic crisis. Interestingly, the men's safety job have the positive effects on the first childbearing while the women's safety careers have the negative effects on it, after the economic crisis. Before the economic crisis, both do not have significant effects on the first childbearing. This findings point out the limitation of women career favor policy, which purpose to raise the fertility rates by making good environments for women having children to work comfortably without the anxiety of child care.

A Comparative Study on the Chemical Characteristics and Antioxidant Effects of Sea Mustards Sourced from Different Areas in Taejongdae (태종대산 5종 돌미역의 화학성분 및 항산화활성 비교)

  • Kim, Hojun;Jayapala, HPS;Jo, Won Hee;Nam, Hyung Sik;Lim, Sun Young
    • Journal of Life Science
    • /
    • v.31 no.6
    • /
    • pp.559-567
    • /
    • 2021
  • This study compared the nutritional characteristics and antioxidant effects of sea mustards sourced from five different areas (Barammaegi, Gultongmeori, Chanmulgae, Johongtaek, and Goraedeung) in Taejongdae, Youngdo, Busan. The contents of total flavonoids and phenols and fatty acid composition were measured. To evaluate their antioxidant effects, 1,1-diphenyl-2-picrylhydrazyl (DPPH) and 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) assays were used. Acetone/methylene chloride (A+M) extracts from all the sea mustards contained higher amounts of total flavonoids and phenols than methanol (MeOH) extracts. Among the sea mustards obtained from the different areas, the total flavonoid and total phenolic content of the A+M extract of the sea mustard from Gultongmeori was 1.44±0.04 mg/g and 1.72±0.06 mg/g, respectively. In terms of the fatty acid composition, the Gultongmeori sea mustard had higher percentages of total n-6, total n-3, eicosapentaenoic acid (EPA, 20:5n-3), and docosahexaenoic acid (DHA, 22:6n-3) than the sea mustards from the other areas. The A+M extract of the sea mustard from Gultongmeori was more effective in terms of scavenging free radicals as compared with that of the other sea mustards, as assessed by the DPPH and ABTS assays (p<0.05). In a 120-minute reactive oxygen species (ROS) production assay, all the extracts tested decreased cellular ROS production induced by H2O2 compared to that produced by exposure to an extract-free control (p<0.05). The extracts from Barammaegi and Gultongmeori had a greater inhibitory effect on cellular ROS production. These results indicated that the antioxidant effects of sea mustards might be associated with a higher amount of flavonoids and phenols. This study suggests that food-processed products from sea mustard can be developed as functional foods for promoting health in the local population.

olymerization behavior and thermal characteristics of two new composites at five temperatures: refrigeration to preheating

  • Jafarzadeh-Kashi, Tahereh Sadat;Mirzaii, Marzieh;Erfan, Mohmmad;Fazel, Akbar;Eskandarion, Solmaz;Rakhshan, Vahid
    • The Journal of Advanced Prosthodontics
    • /
    • v.3 no.4
    • /
    • pp.216-220
    • /
    • 2011
  • PURPOSE. Heat of composite polymerization (HP) indicates setting efficacy and temperature increase of composite in clinical procedures. The purpose of this in vitro experimental study was to evaluate the effects of 5 temperatures on HP of two new composites. MATERIALS AND METHODS. From each material (Core Max II [CM] and King Dental [KD]), 5 groups of 5 specimens each were prepared and their total HPs (J/gr) were measured and recorded, at one of the constant temperatures $0^{\circ}C$, $15^{\circ}C$, $23^{\circ}C$, $37^{\circ}C$ and $60^{\circ}C$ ($2{\times}5{\times}5$ specimens) using a differential scanning calorimetry (DSC) analyzer. The data were analyzed using a two-way ANOVA, a Tukey's test, an independent-samples ttest, and a linear regression analysis (${\alpha}=0.05$). RESULTS. No polymerization reactions occurred at $0^{\circ}C$; then this temperature was excluded from statistical analyses. The mean HP of the remaining 20 KD specimens was $20.5{\pm}14.9$ J/gr, while it was $40.7{\pm}12.9$ J/gr for CM. The independent-samples t-test showed that there were significant differences between the HP of the two materials at the temperatures $15^{\circ}C$ (P=.0001), $23^{\circ}C$ (P=.0163), $37^{\circ}C$ (P=.0039), and $60^{\circ}C$ (P=.0106). Linear regression analysis showed statistically significant correlations between environment temperatures and HP of CM ($R^2=0.777$). CONCLUSION. Using CM is advantageous over conventional composite because of its better polymerization capacity. However due to its high HP, further studies should assess its temperature increase in vivo. Preheating KD is recommended. Refrigerating composites can negatively affect their polymerization potential.

Feasibility as a Laundry Detergent Additive of an Alkaline Protease from Bacillus clausii C5 Transformed by Chromosomal Integration (Chromosomal Integration에 의해 제조한 Bacillus clausii C5 유래의 alkaline protease의 세제 첨가제 응용성)

  • Joo, Han-Seung;Choi, Jang Won
    • KSBB Journal
    • /
    • v.27 no.6
    • /
    • pp.352-360
    • /
    • 2012
  • Bacillus clausii I-52 which produced SDS- and $H_2O_2$-tolerant extracellular alkaline protease (BCAP) was isolated from heavily polluted tidal mud flat of West Sea in Incheon, Korea and stable strain (transformant C5) of B. clausii I-52 harboring another copy of BCAP gene in the chromosome was developed using the chromosome integration vector, pHPS9-fuBCAP. When investigated the production of BCAP using B. clausii transformant C5 through pilot-scale submerged fermentation (500 L) at $37^{\circ}C$ for 30 h with an aeration rate of 1 vvm and agitation rate of 250 rpm, protease yield of approximately 105,700 U/mL was achieved using an optimized medium (soybean meal 2%, wheat flour 1%, sodium citrate 0.5%, $K_2HPO_4$ 0.4%, $Na_2HPO_4$ 0.1%, NaCl 0.4%, $MgSO_4{\cdot}7H_2O$ 0.01%, $FeSO_4{\cdot}7H_2O$ 0.05%, liquid maltose 2.5%, $Na_2CO_3$ 0.6%). The enzyme stability of BCAP was increased by addition of polyols (10%, v/v) and also, the stabilities of BCAP towards not only the thermal-induced inactivation at $50^{\circ}C$ but also the SDS and $H_2O_2$-induced inactivation at $50^{\circ}C$ were enhanced. Among the polyols examined, the best result was obtained with propylene glycol (10%, v/v). The BCAP supplemented with propylene glycol exhibited extreme stability against not only the detergent components such as ${\alpha}$-orephin sulfonate (AOS) and zeolite but also the commercial detergent preparations. The granulized enzyme of BCAP was prepared with approximately 1,310,000 U/g of granule. Wash performance analysis using EMPA test fabrics revealed that BCAP granule exhibited high efficiency for removal of protein stains in the presence of anionic surfactants as well as bleaching agents. When compared to Savinase 6T$^{(R)}$ and Everlase 6T$^{(R)}$ manufactured by Novozymes, BCAP under this study probably showed similar or higher efficiency for the removal of protein stains. These results suggest that the alkaline protease produced from B. clausii transformant C5 showing high stability against detergents and high wash performance has significant potential and a promising candidate for use as a detergent additive.

Immune Reaction of the Vaccinated Hamsters with Combined Hantaan-Puumala Vaccine (신증후출혈열의 혼합백신을 접종한 햄스터에서의 면역성 조사)

  • Lee, Ho-Wang;Chu, Yong-Kyu;Cui, Long-Zhu;Woo, Young-Dae;Ahn, Chang-Nam;Kim, Hoon;Jang, Yang-Seok
    • The Journal of Korean Society of Virology
    • /
    • v.27 no.1
    • /
    • pp.39-47
    • /
    • 1997
  • A large number of viruses belonging to Genus Hantavirus in Family Bunyaviridae are etiologic agents for hemorrhagic fever with renal syndrome (HFRS), or hantavirus pulmonary syndrome (HPS). Hantaan (HTN), Seoul (SED), Belgrade (BEL), Puumala (PUU) serotype viruses are well known causative agents for HFRS in Eurasian continent. Among those viruses Hantaan and Seoul serotypes are well known to cause HFRS in Korea, but there are some sporadic incidence by other than Hantaan or Seoul viruses. Recently we have developed the combined Hantaan-Puumala virus vaccine to prevent world-wide occuring HFRS. This combined vaccine is formalin inactivated, suckling mouse and suckling hamster brain extracts for Hantaan and Puumala viruses, respectively. Protein contents of this purified candidate vaccine is $27\;{\mu}g/ml$, which contains 1,024 ELISA antigen units to each virus, but content of myelin basic protein which is causing experimental allergic encephalomyelitis is less than 0.1 ng/ml. Thirty hamsters were given twice at one month interval intra-muscularly and bled on 30 days after each vaccination from retro-orbital sinus vein. Antibody titers were tested against 5 major serotype viruses, Hantaan, Seoul, Belgrade, Puumala and Sin Nombre viruses by IFA and PRNT. The mean IF antibody titers on 30 days after primary shot were 78.4, 68.8, 68.8, 37.9, and 15.6; mean neutralizing antibody titers were 65.4, 12, 6.1, 65.6 and 0.5 against Hantaan, Seoul, Belgrade, Puumala and Sin Nombre viruses, respectively. The mean IF antibody titers on 30 days after booster shot were 686.9, 567.5, 550.4, 516.3, and 430.9; and neutralizing antibody titers were 710.8, 41.9, 24.3, 409.9, and 1.6 against Hantaan, Seoul, Belgrade, Puumala and Sin Nombre viruses, respectively.

  • PDF