• Asian-Australasian Journal of Animal Sciences
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• 제3권4호
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• pp.323-330
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• 1990

Two experiments were conducted to evaluate the effect of processing and method of ensiling on the digestion and utilization of high moisture barley (HMB) in cattle. In experiment 1, four Holstein heifers were assigned in a Latin square design to diets containing 70% barley, 25% alfalfa hay and 5% supplement on a dry matter (DM) basis. Diets differed only in the type of barley fed: rolled dry barley (R-DB), rolled HBM (R-HMB), ground HMB (G-HMB) or unprocessed HMB (U-HMB). In experiment 2, three Holstein steers were fed 85.2% barley, 10.2% whole plant barley silage and 4.6% supplement on a DM basis. Again, diets differed only in the type of barley fed: R-DB, rolled HMB from a pit silo (Pit-HMB) or rolled HMB from a Harvestore silo (HAV-HMB). In experiment 1, digestibility coefficients for animals fed R-HMB were significantly higher than observed for U-HMB. While not significant, a similar trend for decreased digestibility was observed for R-DB and G-HMB. Animals fed HMB had significantly lower ruminal propionate concentrations. In addition, the rate of degradation of the degradable DM and crude protein (CP) fractions was slower for HMB than for dry barley. In experiment 2, a trend to lower digestibility coefficients was observed for animal fed R-DB compared to those fed Pit-HMB or HAV-HMB. Ruminal propionate concentrations for animals fed R-DB also tended to be higher than for those fed the HMB diets. Dry matter and CP disappearances from nylon bags was substantially lower for Pit-HMB than for R-DB or HAV-HMB. The results suggest that replacement of dry barley by rolled or unprocessed HMB in the diet of animals fed high grain diets may contribute to a more stable rumen environment.

• Perinatology
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• 제28권2호
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• pp.47-58
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• 2017

Objective: We evaluated the Korean mothers' level of awareness of human milk bank (HMB) in order to find out the issues in establishing HMB in Korea. These mothers had infants younger than 18 months old to find out the issues that would help establishment of HMB in Korea. Methods: The survey questionnaire was developed by a team composed by nurses, neonatologists, obstetricians, nutritionists, health care specialists and faculty members. The internet survey was performed by sending emails to mothers who are registered to M family members and have children younger than 18 months. In total, 864 questionnaire were gathered from 114,469 answers and the results were analyzed. Results: Fifty two point eight percent of the respondents had awareness of HMB. 79.4% of subjects agreed with the necessity of HMB. On the basis of multivariate logistic regression analysis, we found that the numbers of children, awareness of HMB, the concern on the HMB in Korea, and the expected problems in establishing HMB in Korea were significant factors when evaluating the necessity of HMB in Korea. The common factors associated with positive thinking of potential users, donors and recipients were the awareness of HMB, and the experience of feeding own breast milk to other's babies. Conclusion: More than half of Korean women were found to agree with the necessity of HMB in Korea, even though they had concern on infection controls and management of HMB and the purpose and function of HMB was not widely educated. The establishment of HMB in Korea would be effective with public education and considering their demands.

• Asian-Australasian Journal of Animal Sciences
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• 제27권9호
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• pp.1285-1292
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• 2014

An in vitro experiment was conducted to evaluate the effects of Aspergillus oryzae culture (AOC) and 2-hydroxy-4-(methylthio)-butanoic acid (HMB) on rumen fermentation and microbial populations between different roughage sources. Two roughage sources (Chinese wild rye [CWR] vs corn silage [CS]) were assigned in a $2{\times}3$ factorial arrangement with HMB (0 or 15 mg) and AOC (0, 3, or 6 mg). Gas production (GP), microbial protein (MCP) and total volatile fatty acid (VFA) were increased in response to addition of HMB and AOC (p<0.01) for the two roughages. The HMB and AOC showed inconsistent effects on ammonia-N with different substrates. For CWR, neither HMB nor AOC had significant effect on molar proportion of individual VFA. For CS, acetate was increased (p = 0.02) and butyrate was decreased (p<0.01) by adding HMB and AOC. Increase of propionate was only occurred with AOC (p<0.01). Populations of protozoa ($p{\leq}0.03$) and fungi ($p{\leq}0.02$) of CWR were differently influenced by HMB and AOC. Percentages of F. succinogenes, R. albus, and R. flavefaciens (p<0.01) increased when AOC was added to CWR. For CS, HMB decreased the protozoa population (p = 0.01) and increased the populations of F. succinogenes and R. albus ($p{\leq}0.03$). Populations of fungi, F. succinogenes (p = 0.02) and R. flavefacien (p = 0.03) were increased by adding AOC. The HMB${\times}$AOC interactions were noted in MCP, fungi and R. flavefacien for CWR and GP, ammonia-N, MCP, total VFA, propionate, acetate/propionate (A/P) and R. albus for CS. It is inferred that addition of HMB and AOC could influence rumen fermentation of forages by increasing the number of rumen microbes.

• Perinatology
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• 제28권1호
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• pp.11-19
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• 2017

Objective: Human milk bank is known as best alternative option for sick infants. However, only two human milk banks (HMBs) are working in Korea. In the present study, we evaluated the awareness on the HMB in female health care provider to find out the issues that would help facilitating HMB establishment in Korea. Methods: The survey questionnaire was developed by a team composed with neonatologists, obstetricians, nurses, nutritionists, and health care specialists. The survey was performed for female health care workers in Soon Chun Hyang Cheonan Hospital between March and June in 2016. Eighty-eight of 110 questionnaires were collected and the results were analyzed. Results: Most of subjects were found to have correct knowledge on the breast milk feeding. However, only 49% of subjects had awareness of the presence of HMB. Unfortunately, less than half of them could get information about HMB by official way including mass media. In addition, 76% of subjects were found not to want to use HMB. Most important reason was found as a concern on the safety of donor milk including life style of donors, infection controls, and possible nutritional loss of banked milk. Conclusion: The purpose and function of HMB was not widely educated and it seems to be one of most important reasons why women have negative concept about HMB in Korea. Thus, further study is warranted with more numbers of subjects after active public education about the HMB.

• 한국통신학회논문지
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• 제37A권12호
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• pp.1133-1139
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• 2012

본 논문에서는 연계 빔형성과 비연계 빔형성 방법이 동시에 가능한 하이브리드 모드 빔형성 (HMB) 방법을 제안한다. HMB는 점근적으로 합 전송 증가율에 있어서 최적의 빔형성 방법임을 증명한다. 다양한 모의 실험을 통해서 HMB는 대칭 간섭 채널 환경에서 연계 빔형성 방법과 거의 동일한 성능을 달성함을 보인다. 또한, 보다 현실적인 비대칭적 간섭 채널 환경에서는 비대칭 채널 환경에서 연계 빔형성의 전력 비효율성으로 인한 성능의 저하를 갖지만, 연계 빔형성 방법보다는 우수한 성능을 갖는다는 것을 보인다.

• 정보처리학회논문지:컴퓨터 및 통신 시스템
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• 제8권7호
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• pp.159-166
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• 2019

상용화된 많은 SSD와 달리 DRAM-less SSD는 원가절감, 전력소모량 감소 등의 이유로 DRAM을 가지고 있지 않다. 따라서 DRAM의 부재로 인해 입출력 성능이 저하될 가능성이 존재하며, 이는 호스트의 메모리 일부를 SSD 컨트롤러가 사용할 수 있는 NVMe 인터페이스의 HMB 기능을 통해 개선할 여지가 있다. 본 논문에서는 현재 상용화된 여러 DRAM-less SSD가 DRAM을 가지고 있는 동급 SSD에 비해 실제로 입출력 성능이 떨어지지만 HMB 기능을 사용해 일부 개선하고 있으며, 이는 SSD 컨트롤러가 호스트의 메모리를 매핑테이블 캐시로 주로 사용하고 있기 때문이라는 점을 다양한 실험을 통해 증명한다.

• 환경생물
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• 제37권1호
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• pp.60-67
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• 2019

본 연구에서는, 한약재 부산물을 흰점박이꽃무지 유충의 먹이원으로 활용하기 위해서, 영양성분 함량, 중금속 함량, 유충의 생육효과에 미치는 영향을 분석했다. 먹이원의 영양성분을 비교한 결과, 조섬유를 제외한 조단백, 조지방, 조회분 함량이 미발효, 발효조건 한약재 부산물 모두에서 높게 나타났으며, 특히 조단백질의 함량이 매우 높게 나타났다. 먹이원의 안정성을 확인하기 위하여 한약재 부산물의 카드뮴, 납, 수은 등의 중금속 분석 결과, 모두 불검출로 먹이원으로써의 안정성을 확인할 수 있었다. 먹이원에 따른 생육 비교에서는 참나무 발효톱밥을 급이한 대조구와 한약재 부산물을 급이한 실험구는 1~3주차까지 큰 차이가 없다가 4주차 유충의 중량이 대조구는 0.137 g, 실험구는 0.671 g으로 유의한 수준에서 차이를 보이기 시작했다. 한약재 부산물 첨가별 급이에 따른 흰점박이꽃무지 유충의 중량을 비교한 결과 7주차에서 HMB40이 가장 높은 중량을 보였다. 통계분석 결과 5주차의 HMB40, HMB80의 각각의 중량과 유의적으로 차이를 보이지 않았다. 이러한 결과는 식용곤충의 출하시기를 3령 유충으로 보았을 때 5주차에 이미 출하시점에 도달했음을 의미하며, 이는 HMB40, HMB80 조건의 급이가 가장 효율적이라는 것을 나타낸다.

• 대한두경부종양학회지
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• 제25권2호
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• pp.150-152
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• 2009

혈관근육지방종은 지방, 평활근, 두꺼운 벽의 혈관이 다양한 비율로 구성된 흔하지 않은 과오종이며, 이는 결정 경화증을 동반하거나 산발적으로 발생한다. 저자들은 혈관근육지방종이 드물게 발생하는 두경부에서 발생한 귓바퀴 1예, 구개점막 2예의 혈관근육지방종을 보고하고자 한다. 병리소견상, 3예 모두에서 성숙지방조직, 불규칙한 혈관, 그리고 HMB-45와 Melan-A에 음성을 보이는 평활근육세포로 이루어진 조직소견을 보였으며, 여러군데에서 림프구 침윤이 3예 모두에서 관찰되었다. 점막피부 혈관근육지방종으로 진단하였다. 세증례 모두 결절경화증은 동반되지 않았다. 점막피부 혈관근육지방종에서는 혈관주변세포가 HMB-45와 Melan-A에서 음성을 보였으며, 이는 간이나 신장의 혈관근육지방종에서의 특징적인 양성반응과는 다른 점이었다. 간이나 신장에서 생긴 혈관근육지방종과 다른 임상병리적 특징을 비교 기술하고자 두경부에서 발생한 점막피부 혈관근육지방종 3예를 보고한다.

• 대한병리학회지
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• 제52권6호
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• pp.363-368
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• 2018

Background: Vitiligo is a chronic autoimmune disease in which the destruction of melanocytes causes white spots on the affected skin. Janus kinase (JAK) is a family of intracellular, non-receptor tyrosine kinases that transduce cytokine-mediated signals via the JAK-signal transducer and activator of transcription pathway. The aim of the present study is to explore the possible role of JAK1 in the pathogenesis of vitiligo using immunohistochemical methods. Methods: The current study was conducted in a sample of 39 patients who presented with vitiligo and 22 healthy individuals who were age and sex matched as a control group. We used immunohistochemistry to evaluate JAK1 status (intensity and distribution) and assess the percentage of residual melanocytes using human melanoma black 45 (HMB45). Results: Intense and diffuse JAK1 expression was significantly more likely to indicate vitiliginous skin compared to normal skin (p<.001). Strong and diffuse JAK1 expression was associated with short disease duration, female sex, and lower percentage of melanocytes (detected by HMB45) (p<.05). Conclusions: JAK1 may be involved in the pathogenesis of vitiligo, as indicated by intense and diffuse expression compared to control and association with lower percentage of melanocytes detected by HMB45 immunostaining.

• 한국도로학회논문집
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• 제7권3호
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• pp.1-10
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• 2005

본 연구에서는 일반 아스팔트 포장에 비해 설계수명을 2배 이상 증대시켜 보수주기를 증진하고 보수비용 및 사용자 비용을 절감할 수 있는 장수명 아스팔트 포장에 대한 포장가속시험 (APT)을 수행하였다 먼저 본 연구에서 개발된 장수명 포장용 고강성기층 혼합물에 대한 기초적인 물성시험을 수행하였다. 포장의 지지력을 비교하고 피로 및 소성변형에 대한 저항성을 평가하기 위하여 일반 및 고강성 기층으로 구성된 총 4개의 시험단면을 건설하였다. 또한 일반 및 고강성 단면은 각각 얇은 단면과 두꺼운 단면으로 구성되었다. 다양한 교통하중에 대한 아스팔트 기층하단의 인장변형률을 측정하였으며 시험결과 고강성 단면의 인장변형이 일반단면에 비해 적게 발생되는 것을 확인하였다. 기층 단면이 얇은 포장단면에 대한 APT 시험결과 윤하중이 180,000회 재하될 때까지 균열은 발생하지 않았다. 기층단면이 두꺼운 포장에 대해 윤하중 90,000회 재하시 일반단면은 5.3mm, 고강성 단면은 3m의 소성변형이 발생하였다. 본 연구에서 개발된 고강성 혼합물은 소성변형 및 피로균열에 대한 저항성이 우수하기 때문에 장수명 포장용 기층재로서 적합한 것으로 판단된다. 또한 다양한 구조해석 결과 일반 혼합물 대신 고강성 혼합물을 사용할 경우 포장의 하중지지력이 증가하기 때문에 아스팔트층의 단면두께를 최소 5cm 이상 줄일 수 있을 것으로 판단된다.