• RED RIBBON
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• s.68
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• pp.8-9
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• 2006

우리는 흔히 에이즈와 HIV를, 감염인과 환자를 혼용해서 사용하고 있다. 엄밀히 얘기하면 에이즈와 HIV, 감염인과 환자는 전혀 다른 개념이다. 2006년 신년호부터는 에이즈에 대한 기본적 지식을 원하는 독자들의 요구에 부응하여 6회에 걸쳐 에이즈에 대한 상식을 게재할 예정이다.

• RED RIBBON
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• s.43
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• pp.6-7
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• 2001

결론부터 말하자면 현재의 기술로서 HIV감염여부를 확인하는 가장 좋은 방법은 기존의 항체 검사방법이며, 언론에서 '유전자검사'로 소개된 HIV 바이러스의 핵산을 검출하는 검사법이 HIV 감염여부를 묻는 문제에 정답을 맞추는 가장 정확한 검사법은 아니라는 것이다.

• 보건세계
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• v.47 no.1 s.521
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• pp.12-15
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• 2000

HIV 감염자가 병원에 입원하며 의사가 가장 먼저 생각하는 일은 어떤 기회감염으로 이런 증상을 갖게 되었을까 하는 것이다. 생각할 수 있는 병도 많고 생각해야 할 병도 많지만 그 중에서도 가장 먼저 떠올리게 되는 것이 결핵이 아닌가 한다. 우선 빈도면에서 비교적 흔하고, 임상증상도 정상인과 같지 않은 점이 많아서 혼돈을 일으키는 경우가 많다. 림프종을 생각할 만큼 크고 빠르게 자란 목의 덩어리도 조직검사를 하면 결핵성 림프절염인 경우가 있고 복강내 림프절이 커지거나 뇌막염을 일으키기도 한다. 결핵약으로 치료를 하는 경우에도 해열되는데 기간이 많이 필요하고 치료 도중에 약화되는 경험을 하기도 하였다. 우리나라에서 발표된 보고에서도 서울대학교에서 발표한 173명의 환자들에서 가장 흔한 기회감염은 결핵이었다. 25$\%$의 환자에서 결핵이 발생하였으며, 환자 100명당 1년 동안의 결핵 발생률은 9.6이었다. 면역부전이 진행할수록 이 빈도는 증가한다고 보고한 바 있다. 따라서 HIV감염자를 관리, 치료하는 경우에는 결핵에 대한 충분한 이해가 필요한데 얼마전 New England Journal of Medicine에 HIV감염자에서의 결핵이라는 제목으로 발표된 자료가 있어 이를 정리하였다. 여러모로 도움이 되는 내용이지만 우리나라에서 사용할 수 있는 약제에 한계가 있고 BCG예방접종을 하기 때문에 피부반응 검사로 결핵발생을 예측하기도 어렵다는 점을 고려하면 모든 내용이 우리나라의 현실에 적용되는 것은 아니다.

• Tuberculosis and Respiratory Diseases
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• v.61 no.6
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• pp.554-561
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• 2006

Background: In AIDS patients, the respiratory tract is one of the most frequently involved site of by an opportunistic infection, and an even common, casual pulmonary infection manifests in a peculiar ways in AIDS patients. In Korea, because of the low prevalence of AIDS, there is insufficient data compared with other Southeast Asian counties. However, considering the sexual behavior of the younger generation, it is expected that it will not be long before AIDS becomes a major public health issue in Korea. This study examined the clinical manifestation of HIV positive people and AIDS patients. The pulmonary manifestion of HIV-positive was evaluated. This study focused on the differences in the clinical manifestation between AIDS patients with pulmonary disease and simple HIV positive people. The characteristics of common pulmonary infections in AIDS patients were also analyzed. Method: The medical records of 28 HIV positive patients who visited the hospital of ChungAng University Hospital from January, 2001 to February, 2006 were analyzed retrospectively. Result: Twenty-seven patients out of 28 HIV positive patients were male and the average age was 40.6(23-65). Patients in their thirties were most commonly affected. Elven patients had pulmonary diseases. Pulmonary tuberculosis (4 cases) and pneumocystis pneumonia (4 cases) were the most common respiratory infection. One patient showed a peculiar type of systemic cryptococcus. which was accompanied by lung and pleural dissemination. The CD4+lymphocyte count of patients with a pulmonary infection was significantly lower in patients with a pulmonary manifestation than those with only a HIV infection ($79.5/mm^3$ vs $400/mm^3$, respectively)(p<.05). Patients with pulmonary disease were in a more severe immunosuppressive state. There were 4 patients with pulmonary tuberculosis, 4 with pneumocystis pneumonia, 4 with secondary syphilis, 2 with primary syphilis, and 2 with HZV infection. The average CD4 lymphocyte counts was $56/mm^3$ in those with pulmonary tuberculosis, $42/mm^3$ in those with pneumocystis pneumonia, and $455/mm^3$ in those with secondary syphilis. Conclusion: This study examined the clinical manifestation of HIV positive patients, particularly AIDS patients with pulmonary disease, A more severe immunosuppressive status was observed in HIV-related pulmonary compared with those with HIV-related extrapulmonary disease, and the frequency of pulmonary tuberculosis in pulmonary disease was higher than expected. Respiratory infection in AIDS manifest in uncommon ways e.g. disseminated cryptococcosis involving the lung and pleura. Evidently, AIDS patients with a respiratory infection have a more severe form of immunosuppression than those with a simple HIV infection. As expected, patients with a pulmonary infection were in a more severe immunosuppressed state than those with a simple HIV infection. Opportunistic infections can show peculiar clinical presentations in AIDS patients.

• Pediatric Infection and Vaccine
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• v.26 no.1
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• pp.66-70
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• 2019

Trans-placental neonatal human immunodeficiency virus (HIV) infection is common in Africa; however, it is not yet reported in the Republic of Korea. With the increasing incidence of HIV infection, especially in the reproductive age group, the risk of the vertical transmission of HIV is also increasing. We report the first case of HIV infection acquired in-utero in a newborn in Korea. The baby is growing well with normal development.

• Journal of Hospice and Palliative Care
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• v.17 no.3
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• pp.142-150
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• 2014

Purpose: This study was to identify the attitude of Korean HIV (Human Immunodeficiency Virus)-positive men toward death. Methods: A Q-methodology was performed with 20 HIV-positive male individuals. Participants were asked to select and answer questions among a set of 40 Q-statements using a 9-point scale. The collected data were analyzed using the PC QUANL program. Results: Participants' attitudes toward death were categorized into four types. Type I was characterized by respect for life, type II by reality orientation, type III by pain evasion and type IV religious beliefs. Conclusion: It is necessary to develop an assessment tool and an intervention program for HIV-positive individuals.

• Journal of Life Science
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• v.32 no.9
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• pp.734-741
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• 2022

Currently, around 40 million people worldwide are living with human immunodeficiency virus (HIV) infection making HIV a critical global health risk. Present therapies for HIV infection consist of drug cocktails that target different steps of the HIV life cycle to prevent infection, replication, and release of the virus. Due to its mutating nature, drug resistance coupled with side-effects of long-term drug use, novel strategies, and pharmaceuticals to treat and manage HIV infection are constant needs and continuously being studied. Plants allocate a major repertoire of chemical diversity and are therefore regarded as an important source of new bioactive agents that can be utilized against HIV. Since the early 1990s, upon recommendations of the World Health Organization, numerous studies reported phytochemicals from different structural classes such as flavonoids, coumarins, tannins and terpenes with strong inhibitory effects against HIV infection. The present review gathered and presented recent research (2021-present) on plant extracts and phytochemicals that exhibit anti-HIV properties with the aim of providing insights into future studies where ethnomedical and underutilized plant sources may yield important natural products against HIV. Considering the relation and importance of HIV treatment with current viral infection risks such as SARS-CoV-2, screening plants for anti-HIV agents is an important step towards the discovery of novel antivirals.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.9
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• pp.216-225
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• 2017

The purpose of this study is to examine the effect of spirituality on the quality of life in people living with HIV/AIDS. The survey was conducted with 260 people living with HIV/AIDS to analyze the effect of sociodemographic factors, spiritual experience in ordinary life, value and belief, forgiveness, personal religious life, religious/spiritual response skills and the spiritual factor of religious support. As a result of the OLS regression analysis, the income level, seriousness of illness, forgiveness and religious/spiritual response skill were found to have an effect on the quality of life of people living with HIV/AIDS. This study proved that spiritual factors as well as demographic factors strongly influence the quality of life in people with HIV/AIDS. In summary, the effect of spirituality on the quality of life was discussed and on the basis of the results, it is deemed necessary to emphasize spirituality factors to improve the mental health of people living with HIV/AIDS. The limitations of this study are discussed and future investigations envisaged.

• RED RIBBON
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• s.51
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• pp.36-37
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• 2003

지난해 국내 HIV감염자수 2,000명을 돌파 국립보건원은 감염경로가 대부분 성접촉에 의한 것으로 확인되어 에이즈예방을 위해 콘돔사용에 대한 홍보와 콘돔보급에 힘쓸 계획

• RED RIBBON
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• s.66
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• pp.42-43
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• 2005

질병관리본부는 올 1월부터 6월까지 신규로 HIV에 감염된 내국인은 총 317명이라고 밝혔다. 이 수치는 작년 상반기 302명에 비해 $5\%$ 소폭 증가한 것이다. 정부 발표에 따르면 2005년 6월말 현재 국내 누적감염인수는 총 3,468명이며 이중 680명은 이미 사망하여 2,788명이 생존하고 있는 것으로 나타났다.