• Korean Journal of Applied Biomechanics
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• v.29 no.3
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• pp.197-204
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• 2019

Objective: The purpose of this study was to identify the effect of high-heels (HH) modification on metatarsal stress in female workers. Method: Seven females who work in clothing stores ($heights=160.4{\pm}3.9cm$; $weights=47.4{\pm}4.1kg$; $age=31.3{\pm}11.1yrs$; $HH\;wear\;career=8{\pm}6.5yrs$) wore two types of HH (original and modified). The modified HH had been grooved with 1.5 cm radius and 0.2 cm depth around the first metatarsal area inside of the shoes using the modified shoe-last. Participants were asked to walk for 15 minutes on a treadmill and to stand for 10 minutes with original and modified HH, respectively. Kinetics data were collected by the F-scan in-shoe system. After each test, participants were asked to rate their perceived exertion using the Borg's 15-grade RPE scale and interviewed about their feeling of HH. Nonparametric Wilcoxon signed-rank test and effect size (Cohen's d) were used to determine the difference of the variables of interest between the original and modified HH. Results: In the present study, modified HH of the peak contact pressure of 1st metatarsal (PCP) left, PCP right, pressure time integral (PTI) left, peak pressure gradient (PPG) left during standing and PPG right during walking are greater than original HH. And even it didn't show statistically significant, the average in all pressure values of modified HH showed bigger than original HH. It surmised to be related to awkward with modified HH. Even though they said to feel the comfortable cause of big space inside of HH in the interview, they seemed to be not enough time to adapt with new HH. So their walking and standing postures were unstable. Conclusion: Modified the fore-medial part of HH can reduce the stress in the first metatarsal head and big toe area during standing and walking.

• The Journal of the Korean bone and joint tumor society
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• v.13 no.2
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• pp.67-74
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• 2007

Purpose: To evaluate association of giant cell tumors recurrence between markers of proliferation cells (MCM3, Ki-67 and HH3) Materials and Methods: Ten case of giant cell tumor of bone were reviewed. The patients were six males and four females (mean age: 33 yrs). All patients were done operation after biopsy. The radiologic grading was determined according to Enneking grading system. The immunohistochemical stains of MCM3, HH3, and Ki-67 were done with Microarray block. Results: The three cases of 10 cases (30%) were recurred at same sites. Two case of recurrence was grade II according to radiologic features. The remaining case was grade I. The expression rate of immunohistochemical markers in radiologic grade 2 and 3 were more increased than grade 1. But there was not association between radiologic grading and proliferation of tumor cells because result data was not coherence. Mean MCM3 labeling index of non-recurred case was 11.2%, recurred case was 7.2%. Ki-67 was 12% vs. 8.9%, respectively and HH3 was 66.9 % vs. 75.4%, respectively. Thus there was no association between local recurrence and immunohistochemical Ki-67, MCM3 expression rate. But HH3 marker expression rate was increased in recurred cases compared to non-recurred cases. Conclusion: Our study suggests that HH3 immunohistochemical marker can be a useful prognostic factor.

• The Bulletin of The Korean Astronomical Society
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• v.40 no.1
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• pp.69.1-69.1
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• 2015

Classical T Tauri star DG Tau is suggested as the driving source of parsec-scale jet which expands up to 650" (0.4 pc). To investigate the kinematics and physical properties of the jet, we have obtained the optical emission lines of $H{\alpha}$, [O I] ${\lambda}{\lambda}$6300, 6363, [N II] ${\lambda}{\lambda}$6548,6584, and [S II] ${\lambda}{\lambda}$6716, 6731 from HH 158 ad HH 702. The radial velocity of HH 158 is in the range of -50 to $-250km\;s^{-1}$. For HH 702, located at 650" from the source, it shows ~ $-80km\;s^{-1}$. In HH 158, the electron density ($n_e$) close to the star is ${\sim}10^4cm^{-3}$ and it decreases to ${\sim}10^2cm^{-3}$ at 14" away from the star. Electron temperature ($T_e$) is decreasing from >15,000 K to ~5,000 K with distance. Ionization fraction ($x_e$) is increasing from almost zero to > 0.4 along the distance. In HH 702, the values of $n_e$, $T_e$, and $x_e$ are similar to those estimated at 14" from source, where knot C of HH 158 is located. This may imply that the physical properties of the knot could persist through such a long distance in the space, and the gas could be re-excited by the shock during propagation of the jet. On the other hand, we cannot avoid the possibility that HH 702 is driven by another source rather than DG Tau because HH 158 and HH 702 show somewhat large difference in their inclination angles (${\Delta}i=21-35^{\circ}$).

• Research in Community and Public Health Nursing
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• v.30 no.1
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• pp.99-107
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• 2019

Purpose: This study aimed to assess hand hygiene (HH) compliance among visitors at a long-term care hospital in South Korea. Methods: The study was conducted at a 502-bed long-term care hospital located in Gyeonggi-do Province. From July 1 to August 15, 2017, including more than 6 weekends and one holiday, a trained observer covertly assessed visitors' HH at all five units (360 beds in total) of the study hospital building until the completion of 1,000 HH opportunities (i.e., 200 opportunities per unit). The modified World Health Organization (WHO) HH observation form was used. Instead of professional categories and the "before clean/aseptic procedure" moment, the estimated age range for each visitor were recorded in four categories: children (<14 years old), adolescents (14~18), adults (19~64), and the elderly (${\geq}65$). The collected data were analyzed using SPSS 22.0. Results: A total of 1,000 HH opportunities were observed from 766 visitors (an average of 1.31 per visitor) and the overall HH compliance rate was 20.3%. Overall, 53.7% of the HH cases were performed with soap and water. Among the 4 HH moments, the "after body fluid exposure risk" moment showed the highest compliance rate (83.5%); 93.9% used soap and water. The most commonly exposed potential body fluid among visitors was saliva (48.1%). Conclusion: For hospital visitors in long-term care hospitals, HH education programs including HH moments need to be developed and implemented. Further studies are necessary to evaluate visitors' HH compliance in various hospital settings and find the related variables influencing visitors' HH.

• Journal of Preventive Medicine and Public Health
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• v.51 no.3
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• pp.121-129
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• 2018

Objectives: To assess the nurses' hand hygiene (HH) knowledge, perception, attitude, and self-reported performance in small- and medium-sized hospitals after Middle East Respiratory Syndrome outbreak. Methods: The structured questionnaire was adapted from the World Health Organization's survey. Data were collected between June 26 and July 14, 2017. Results: Nurses showed scores on knowledge ($17.6{\pm}2.5$), perception ($69.3{\pm}0.8$), self-reported HH performance of non-self ($86.0{\pm}11.0$), self-reported performance of self ($88.2{\pm}11.0$), and attitude ($50.5{\pm}5.5$). HH performance rate of non-self was $Y_1=36.678+0.555X_1$ (HH performance rate of self) (adjusted $R^2=0.280$, p<0.001). The regression model for performance was $Y_4=18.302+0.247X_{41}(peception)+0.232X_{42}(attitude)+0.875X_{42}(role model)$; coefficients were significant statistically except attitude, and this model significant statistically (adjusted $R^2=0.191$, p<0.001). Conclusions: Advanced HH education program would be developed and operated continuously. Perception, attitude, role model was found to be a significant predictors of HH performance of self. So these findings could be used in future HH promotion strategies for nurses.

• Perspectives in Nursing Science
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• v.12 no.1
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• pp.7-13
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• 2015

Purpose: This observational study was aimed to determine the influence of the Hawthorne effect on the adherence to hand hygiene (HH) among healthcare workers (HCWs) in South Korea. Methods: HCWs were monitored in 2 periods regarding adherence to HH when there were indications for HH. In first period, HCWs recognized that their behavior of hand hygiene being observed (overt observation), and did not recognize in second period (covert observation). Results: The overall difference in HH rate between two periods was 45.0% point (77.8% vs 32.8%). There were significant differences between profession but in nurse aids. The differences in HH rate between two periods were 46.1% point in nurses, 29.9% point in physicians, 64.0% in radiologists, 62.5% point in laboratory technicians, 36.4% point in physio-therapist, and 1.0% point in nurse aids. The Hawthorne effect on the adherence to HH lasted more than 3 months. Conclusion: The Hawthorne effect markedly influence on the adherence to HH regardless of profession except nurse aids. Therefore, Hawthorne effect can be useful tool to improve and sustain the adherence to HH among HCWs in South Korea.

• Korean Journal of Poultry Science
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• v.41 no.1
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• pp.53-59
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• 2014

To evaluate the meat quality differences of Korean Native Chickens (KNC) available in Korean market, the physicochemical and sensory characteristics of a broiler and two KNC (HH and WD breed) were analyzed. The fat content of KNC WD breast meat was higher than that of KNC HH. The breast and thigh meats of KNC HH had higher $L^*$ and $a^*$ values than the broiler or the KNC WD. WD meats showed greater DPPH radical scavenging activity and higher pH values than the HH. For the fatty acid composition, there was no significant difference in total content of the saturated fatty acids among chicken breeds (p>0.05). KNC had greater content of polyunsaturated fatty acids, especially arachidonic acid (20:4) and DHA (22:6), compared with the broiler. KNC WD meats had higher composition of linolenic acid (18:3) than the KNC HH. For sensory evaluation, the WD breast meat showed higher taste and tenderness scores than the HH. On the other hand, the soup made by broiler had higher taste scores than the KNC. The breast and thigh meat from two KNC breeds showed different quality parameters that may come from the differences of genetic attributes, feed, and production strategy between two breeds.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.37 no.3
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• pp.199-210
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• 2011

This study was conducted to develop functional sources of herbal cosmetics for treatment of skin aging and inflammatory disorders using volatile flavor extracts of four different herbal medicinal prescriptions including Cnidium officinale Makino (COM), Angelica gigas Nakai (AGN), Mentha arvense L. (MAL), Artemisiae argyi Folium (AAF), Paeonia lactiflora Pall (PLP), Rehmanniae Radix Preparata (RRP), Scutellaria baicalensis Georgi (SBG), Panax ginseng C.A. Meyer (PGM), Glycyrrhiza uralensis Fisch (GUF). The volatile flavor extracts of four different herbal medicinal prescriptions (HH-1: COM, AGN, PLP, RRP, HH-2: COM, AGN, PLP, RRP, SBG, PGM, GUF, HH-3: COM, AGN, MAL, AAF, HH-4: COM, AGN, MAL, AAF, SBG, PGM, GUF) were extracted using SDE and their antioxidant and anti-inflammatory effects were measured by using DPPH radical and SLO, respectively. As a result, HH-2 showed moderate DPPH radical scavenging activity (68.24 %) and the strongest SLO inhibitory activity (83.96 %) at 100 ${\mu}g$/mL. Moreover, HH-2 of four different prescriptions significantly inhibited NO production on LPS-stimulated RAW 264.7 cells in a dose-dependent manner without considerable cell cytotoxicity at range of 2.0 ~ 50 ${\mu}g$/mL. Additionally, HH-2 also effectively suppressed the production of $PGE_2$ and IL-6, which are responsible for promoting the inflammatory process. Major volatile components of HH-2 were identified as eugenol, paeonol, butyl phthalide, ${\beta}$-eudesmol and butylidene dihydrophthalide by GC-MS analysis. Thus, these results suggest that HH-2 may be useful as a potential source of anti-inflammatory agents in herbal medicinal cosmetics.

• Journal of Microbiology
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• v.38 no.3
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• pp.160-168
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• 2000

A-factor I a microbial hormone that can positively control cell differentiation leading to spore formation and secondary metabolite formation in Streptomyces griseus. to identify a protease that is deeply involved in the morphological and physiological differentiation of Streptomyces, the proteases produced by Streptomyces griseus IFO 13350 and its A-factor deficient mutant strain, Streptomyces griseus HH1, as well as Streptomyces griseus HH1 transformed with the afsA gene were sturdied. In general Streptomyces griseus showed a higher degree of cell growth and protease activity in proportion to its ability to produce a higher amount of A-factor. In particular, the specific activity of the trypsin of Streptomyces griseus IFO 13350 was greatly enhanced more than twice compared with that of Streptomyces griseus HH1 in the later stage of growth. The specific activity of the metalloprotease of Streptomyces griseus HH1 was greatly enhanced more than twice compared with that of Streptomyces griseus IFO 13350, and this observation was reversed in the presence of thiostreptione, However, Streptomyces griseus HH1 transformed with the afsA gene showed a significantly decreased level of trypsin and metalloprotease activity compared with that of the HH1 strain. There was no significant difference between Streptomyces griseus IFO 13350 and HH1 strain in their chymotrypsin and thiol protease activity, yet the level of leu-amionpeptidase activity was 2 times higher in Streptomyces griseus HH1 than in strain IFO 13350 . Streptomyces griseus HH1 harboring afsA showed a similar level of enzyme activity , however, all the three protease activities sharply increased and the thiol protease activity was critically increased at the end of the fermentation. When a serine protease inhibitor, pefabloc SC, and metalloprotease inhibitor, EDTA, were applied to strain IFO 13350 to examine the in vivo effects of the protease inhibitors on the morpholofical differentiation, the formation of aerial meycelium and spores was delayed by two or three days.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.16 no.9
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• pp.6160-6168
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• 2015

Hand hygiene(HH)of the health care personnels(HCPs) was the most effective method to prevent the transmission of healthcare associated infections. This study was conducted to measure and analysis the status of the HH compliance of HCPs. Data were collected by the direct observation methods of the World Health Organizations(WHO) using WHO's HH monitoring tool kits from 25th October to 31th December, 2010. Data were analyzed by descriptive statistics, cross analysis, multiple logistic analysis using the SPSS/PC 21 program. A total of 8,644 opportunities for HH were observed, and the overall HH compliance rate was 94.1%. HH rates of physicians was lowest(83.4%; OR: 0.209, 95%CI:0.174-0.252). HH rates were statistically different by the job titles(p<0.001), WHO's 5 moments(p<0.001). HH rates in registered nurses(p=0.003), and medical technicians(p<0.001) were statistically different by the WHO 5Moments. Jobs specific HH strategies and WHO 5Moments should be developed to increase the HH compliances of the HCPs.