• Title/Summary/Keyword: HEV-3

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The Correlation between ALT (Alanine Aminotransferase) Value and Prevalence of Anti-HEV (ALT (Alanine Aminotransferase) 검사성적과 E형 간염항체 양성률간의 관련성)

  • 곽준석;옥치상
    • Environmental Analysis Health and Toxicology
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    • v.13 no.3_4
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    • pp.63-70
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    • 1998
  • In order to elucidate the prevalence of anti-HEV, anti-HCV and HBsAg in ALT (Alanine Aminotransferase)-elevated patient group and healthy person control group, we examined anti-HEV, anti-HCV and HBsAg in 92 persons, respectively. The prevalence of anti-HEV in ALT-elevated patient group (4.3%) was not significantly higher than that (2.2%) of healthy person control group(P>0.05). While in healthy person control group the prevalence of anti-HEV in female (2.4%) was higher than that (2.0%) in male, and in ALT-elevated group male (4.8%) was higher than female (3.3%), there were no significances. The positive rate of anti-HEV was not significantly increased with age between healthy person control and ALT-elevated patient group. The odds ratio's of HEV, HCV and HBV with ALT-elevated patient group were 2.05 (95% CI: 0.31-16.54), 8.67 (95% CI: 1.06-188.63) and 7.23 (95% CI: 2.47-22.71), respectively, but had no significance. It was turned out that HCV and HBV were significantly correlated with ALT-elevated patient group, but HEV had no significance with it in this paper.

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First report of cross-species transmission of deer hepatitis E virus to a guanaco in Korea

  • Park, Byung-Joo;Yi, Ji-Hyung;Ahn, Hee-Seop;Han, Sang-Hoon;Kim, Yong-Hyun;Go, Hyeon-Jeong;Kim, Dong-Hwi;Lee, Joong-Bok;Park, Seung-Yong;Song, Chang-Seon;Lee, Sang-Won;Choi, In-Soo
    • Journal of Preventive Veterinary Medicine
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    • v.41 no.3
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    • pp.121-123
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    • 2017
  • The hepatitis E virus (HEV) is a leading causative agent of acute hepatitis in humans. Zoonotic HEV strains have been isolated from several animal species, including pigs. New HEV variants have been recently isolated from camels in the Middle East. In the present study, fecal samples from fallow deer, formosan deer, alpaca, and guanaco were analyzed for the detection of HEV. One HEV strain was detected from guanaco, a species of camelids. The nucleotide sequence of guanaco HEV was identical to those of deer HEV-3 strains, which implied the cross-species transmission of HEV-3 from deer to guanaco.

Identification of Hepatitis E Virus in Bovine and Porcine Raw Livers

  • Go, Hyeon-Jeong;Park, Byung-Joo;Ahn, Hee-Seop;Lyoo, Eu-Lim;Kim, Dong-Hwi;Lee, Joong-Bok;Park, Seung-Yong;Song, Chang-Seon;Lee, Sang-Won;Choi, In-Soo
    • Journal of Microbiology and Biotechnology
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    • v.29 no.12
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    • pp.2022-2025
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    • 2019
  • Several animal species including pigs are directly involved in the zoonotic transmission of the hepatitis E virus (HEV) to humans. This study was conducted to detect HEV in bovine and porcine raw livers by nested reverse transcription-polymerase chain reaction. Zoonotic HEV strains were identified in 1.0 and 3.0% of the tested bovine and porcine livers, respectively. HEV-4 was detected in the bovine livers, but both HEV-3 and HEV-4 were identified in the porcine livers. These results indicate that zoonotic transmission of HEV may occur via consumption of raw or undercooked livers of pigs and cattle.

Genetic Characterization for Human Enterovirus Isolated from Busan Region in Korea (부산지역에서 분리된 엔테로바이러스의 유행양상 분석 및 유전자형 연구)

  • Kim, Nam-Ho;Min, Sang-Kee;Park, Eun-Hee;Park, Yon-Koung;Kwan, Sun-Mok;Jin, Seong-Hyeon
    • Journal of Life Science
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    • v.20 no.6
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    • pp.907-913
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    • 2010
  • Human enteroviruses (HEV) are considered one of the major infectious causes of central nervous system infections such as aseptic encephalomeningitis in pediatrics. This study was focused on providing information related to genetic characteristics and diversities of HEV which prevailed between 2007 and 2009 in Busan, Korea. A total of 2,743 specimens were collected from children and screened for isolation of HEV by cell culture and RT-PCR. Among the specimins, 240 isolates were grouped into 21 different HEV serotypes using VP1 RT-PCR. The major etiological agents were CV-A6 and CV-B2 in 2007, E-6 and E-30 in 2008 and CV-B1 in 2009. The occurrence of HEV infections was the most frequent in the summer (May to August, 188 cases, 78.3%). Most of the isolates were identified from specimens from children under 10 years old, with the highest occurrence in the 2 to 4 year old range (15.2%). However, there were no significant differences between male and female children for the isolates. For analyzing genetic characterization, VP1 gene was amplified by RT-PCR and sequenced. The phylogenetic tree was established by Clustal W method using DNASTAR software. Using the sequence analysis of the VP1 region, it was classified into 2 groups; HEV-A and HEV-B. The HEV-A group contained 6 serotypes and sequences of 31 isolates were compared within each serotype. The HEV-B group contained 10 serotypes and the sequences of 41 isolates were compared within each serotype. Homology analysis of the VP1 region showed that the identity scores of HEV-A and B isolates were different. In conclusion, genetic divergences were observed among the isolates from children between 2007 and 2009 in Busan.

Design of HEV-Relay to Improve Impact and Bounce Characteristics (충격 및 바운스 특성 향상을 위한 HEV-Relay의 설계)

  • Ko, Youn-Ki;Cho, Sang-Soon;Huh, Hoon;Lee, Sang-Yoeb;Park, Hong-Tae;Oh, Il-Sung
    • Proceedings of the KSME Conference
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    • 2008.11a
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    • pp.491-496
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    • 2008
  • A HEV-relay plays a significant role as a mechanical switch which determines the operation of a gasoline engine or an electric motor in a hybrid electric vehicle (HEV). The HEV-relay has critical two problems in the operating process. First, the unstable current can occur in the operating process of the HEV-relay due to the severe bounce between moving and fixed electrode. Second, noises occur due to impact between electrodes in HEV-relay. In this research, spring properties such as stiffness and initial compression force, and electrode shape are designed to reduce the bounce time and noises caused by impact between moving and fixed electrode. The operating process of HEV-relay is simulated using LS-DYNA3D as explicit finite element code. The optimum spring properties are determined using the response surface method (RSM) as the design methodology, and the electrode shape is newly designed through the modifying the stiffness of moving and fixed electrode.

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A driving scheme with a constant engine power and variable battery power in series HEV (일정 엔진출력/가변 전지 출력으로 구동되는 질렬형 HEV의 연계운전 방안)

  • 박영수;허민호;안재영;강신영;김광헌
    • The Transactions of the Korean Institute of Power Electronics
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    • v.5 no.3
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    • pp.285-290
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    • 2000
  • 본 논문에서는 기존 HEV의 단점을 보완한 일정 엔진-발전기 출력/가변 전지 출력의 직렬형 HEV를 제안하고 직렬형 HEV 등가실험장치를 구성하였다. 제안된 연계운전방식은 엔진/발전기 출력을 일정하게 유지해서 전동기에서 요구하는 출력이 발전기를 출력보다 크면 전지에서 방전을 하고 전동기에서 요구하는 출력이 발전기 출력보다 작으면 전지에 충전을 하게된다. 내연기관 시뮬레이션과 로드 프로파일을 통한 실험결과로부터 적은 배기가스 방출량과 높은 에너지 효율을 갖는 직렬형 HEV 최적운전방식으로 이용될 수 있음을 증명하였다.

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Use of IMS-RT-PCR for the Rapid Isolation and Detection of Hepatitis A Virus from the Swine Feces (IMS-RT-PCR을 활용한 육성돈 분변으로부터 간염 A형 바이러스의 신속순수분리 및 검출법 연구)

  • Lee, Hee-Min;Kim, Duwoon
    • Korean Journal of Food Science and Technology
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    • v.44 no.5
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    • pp.638-642
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    • 2012
  • Human pathogenic viruses such as hepatitis A and E virus (HAV and HEV), which lead to acute liver failure and death, are foodborne pathogens associated with the consumption of virus-contaminated meats, filter-feeding bivalves, fruits, and salads. Two of the three swine farms examined in this study had HAV and HEV positive stool samples in a nested RT-PCR assay. The use of the immunomagnetic separation (IMS) facilitated the separation of HAV through interactions between the ligand on the virion surface and the antibody from the swine feces containing both HAV and HEV. The nested RT-PCR analysis was performed for the detection of HAV obtained from hepatocarcinoma cell line (PLC/PRF/5) contaminated with eluent fraction of IMS. This indicated that IMS has the potential to simultaneously isolate and concentrate target viruses by changing antibodies linked on the magnetic beads.

Evaluation of Fuel Economy for a Parallel Hybrid Electric Vehicle

  • Park, Dookhwan;Kim, Hyunsoo
    • Journal of Mechanical Science and Technology
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    • v.16 no.10
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    • pp.1287-1295
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    • 2002
  • In this work, the fuel economy of a parallel hybrid electric vehicle is investigated. A vehicle control algorithm which yields operating points where operational cost of HEV is minimal is suggested. The operational cost of HEV is decided considering both the cost of fossil fuel consumed by an engine and the cost of electricity consumed by an electric motor. A procedure for obtaining the operating points of minimal fuel consumption is introduced. Simulations are carried out for 3 variations of HEV and the results are compared to the fuel economy of a conventional vehicle in order to investigate the effect of hybridization. Simulation results show that HEV with the vehicle control algorithm suggested in this work has a fuel economy 45% better than the conventional vehicle if braking energy is recuperated fully by regeneration and idling of the engine is eliminated. The vehicle modification is also investigated to obtain the target fuel economy set in PNGV program.

Study on the Strip Layout Design of HEV UV Terminal (HEV UV단자의 스트립 레이아웃설계에 관한 연구)

  • Choi, Kye-Kwang;Jo, Yun-Ho
    • Proceedings of the KAIS Fall Conference
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    • 2010.05b
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    • pp.1166-1168
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    • 2010
  • 본 논문에서는 HEV UV단자를 자동화 모듈인 씨마트론 다이 디자인을 활용하여 스트립 레이아웃설계를 3D로 하였다. 제품의 스탬핑을 원활하게 하기 위하여 스트립 레이아웃을 33.5도 경사지게 수정하여 광폭 1열 1개 뽑기의 내측캐리어를 단 배열로 블랭크 레이아웃을 최적화하였다. 1개의 금형에서 두개의 단자를 공용으로 양산하기 29개 공정으로 3D 스트립 레이아웃설계를 완성하였다.

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A Study on the Temperature Characteristics of High Voltage Power Cable for Hybrid Electric Vehicle (하이브리드 자동차용 고압 케이블의 온도 특성에 관한 연구)

  • Lee, Ki-Yeon;Kim, Dong-Woo;Kim, Dong-Ook;Gil, Hyoung-Jun;Kim, Hyang-Kon;Choi, Chung-Seog
    • The Transactions of the Korean Institute of Electrical Engineers P
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    • v.57 no.3
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    • pp.338-342
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    • 2008
  • Hybrid Electric Vehicle(HEV) is driven by an internal-combustion engine and an electric motor. It is a combination of an internal-combustion engine and several electrical equipments which use a high voltage battery, an electric motors, an inverter and others. But there is not any separate detailed enforcement regulations for high voltage electric appliances in the existing vehicle-related safety standards. So, test standards suggestion as well as test technique development need to be done for ensuring electrical safety, for an electric motor, a high voltage battery, a(n) inverter/converter and an electric power transmission units and other equipments to ensure the safety of high voltage electric appliances which is the HEV key electrical component. In this paper, We are to provide helpful data to support test technique development and test standard establishment for HEV design and electrical safety security by the following methods; by measuring the voltage, the electric current, and the frequency of HEV, by analyzing electrical characteristics of high voltage electric appliances, and by analyzing temperature characteristics of the electrical current among the analyzed electrical characteristics by thermal imagining cameras.