• 제목/요약/키워드: HER2-negative

검색결과 247건 처리시간 0.031초

외래이용빈도 분석의 모형과 기법 (A Ppoisson Regression Aanlysis of Physician Visits)

  • 이영조;한달선;배상수
    • 보건행정학회지
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    • 제3권2호
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    • pp.159-176
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    • 1993
  • The utilization of outpatient care services involves two steps of sequential decisions. The first step decision is about whether to initiate the utilization and the second one is about how many more visits to make after the initiation. Presumably, the initiation decision is largely made by the patient and his or her family, while the number of additional visits is decided under a strong influence of the physician. Implication is that the analysis of the outpatient care utilization requires to specify each of the two decisions underlying the utilization as a distinct stochastic process. This paper is concerned with the number of physician visits, which is, by definition, a discrete variable that can take only non-negative integer values. Since the initial visit is considered in the analysis of whether or not having made any physician visit, the focus on the number of visits made in addition to the initial one must be enough. The number of additional visits, being a kind of count data, could be assumed to exhibit a Poisson distribution. However, it is likely that the distribution is over dispersed since the number of physician visits tends to cluster around a few values but still vary widely. A recently reported study of outpatient care utilization employed an analysis based upon the assumption of a negative binomial distribution which is a type of overdispersed Poisson distribution. But there is an indication that the use of Poisson distribution making adjustments for over-dispersion results in less loss of efficiency in parameter estimation compared to the use of a certain type of distribution like a negative binomial distribution. An analysis of the data for outpatient care utilization was performed focusing on an assessment of appropriateness of available techniques. The data used in the analysis were collected by a community survey in Hwachon Gun, Kangwon Do in 1990. It was observed that a Poisson regression with adjustments for over-dispersion is superior to either an ordinary regression or a Poisson regression without adjustments oor over-dispersion. In conclusion, it seems the most approprite to assume that the number of physician visits made in addition to the initial visist exhibits an overdispersed Poisson distribution when outpatient care utilization is studied based upon a model which embodies the two-part character of the decision process uderlying the utilization.

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Perinatal outcome and possible vertical transmission of coronavirus disease 2019: experience from North India

  • Sharma, Ritu;Seth, Shikha;Sharma, Rakhee;Yadav, Sanju;Mishra, Pinky;Mukhopadhyay, Sujaya
    • Clinical and Experimental Pediatrics
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    • 제64권5호
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    • pp.239-246
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    • 2021
  • Background: The consequences of severe acute respiratory syndrome corona virus 2 on mother and fetus remain unknown due to a lack of robust evidence from prospective studies. Purpose: This study evaluated the effect of coronavirus disease 2019 (COVID-19) on neonatal outcomes and the scope of vertical transmission. Methods: This ambispective observational study enrolled pregnant women with COVID-19 in North India from April 1 to August 31, 2020 to evaluate neonatal outcomes and the risk of vertical transmission. Results: A total of 44 neonates born to 41 COVID-19-positive mothers were evaluated. Among them, 28 patients (68.3%) (2 sets of twins) were delivered within 7 days of testing positive for COVID-19, 23 patients (56%) (2 sets of twins) were delivered by cesarean section; 13 newborns (29.5%) had low birth weight; 7 (15.9%) were preterm; and 6 (13.6%) required neonatal intensive care unit admission, reflecting an increased incidence of cesarean delivery and low birth weight but zero neonatal mortality. Samples of cord blood, placental membrane, vaginal fluid, amniotic fluid, peritoneal fluid (in case of cesarean section), and breast milk for COVID-19 reverse transcription-polymerase chain reaction tested negative in 22 prospective delivery cases. Nasopharyngeal swabs of 2 newborns tested positive for COVID-19: one at 24 hours and the other on day 4 of life. In the former case, biological samples were not collected as the mother was asymptomatic and her COVID-19 report was available postdelivery; hence, the source of infection remained inconclusive. In the latter case, all samples tested negative, ruling out the possibility of vertical transmission. All neonates remained asymptomatic on follow-up. Conclusion: COVID-19 does not have direct adverse effects on the fetus per se. The possibility of vertical transmission is almost negligible, although results from larger trials are required to confirm our findings.

기혼여성의 우울감과 가족가치관과의 관련성 연구: 제4차 여성가족패널조사(2012) 자료분석 (Association of Family Values with Depressive Mood in Korean Married Women: The 4th Korean Longitudinal Survey of Women and Families Panel)

  • 박소진;김노을;임승지;김지만;정우진
    • 보건행정학회지
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    • 제28권2호
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    • pp.151-161
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    • 2018
  • Background: Family values of a married woman may be related to her own depressive mood. Since depressive mood of a married woman is likely to exert a negative influence, in terms of mental health, on her, her family members, and the whole society's, it may be very important to explore the relationship between family values in married women and their depressive mood. Methods: In this study, we analyzed nationally representative 5,818 married women aged 20 years or older from the 4th panel data of 2012 Korean Longitudinal Survey of Women and Families. As for variables of interest, we constructed three family values variables: family-oriented view of marriage, individualistic view of marriage, and traditional view of marital roles. Then we employed multivariate logistic regression analyses to explore the relationship between family values and depressive mood, adjusting for family and socio-demographic factors. Results: In total, 804 married women (18.4%) had experienced depressive mood. All of the three family values variables were significant in their relationships with depressive mood. The women categorized as 'very weak' in family-oriented view of marriage were more likely to experience depressive mood than the women categorized as 'very strong' (odds ratio [OR], 1.98; 95% confidence interval [CI], 1.53-2.55). By contrast, the women categorized as 'very weak' in individualistic view of marriage (OR, 0.43; 95% CI, 0.33-0.55) and in traditional view of marital roles (OR, 0.68; 95% CI, 0.51-0.92) were less likely to experience depressive mood than their respective counterpart women categorized as 'very strong.' Conclusion: In Korea, married women's values towards marriage itself and roles between wives and husbands had significant associations with their depressive mood. This suggests that in order to improve mental health in married women, we need to take social and cultural dimensions into consideration along with public health interventions.

일부 청소년에서 음료섭취, 식행동, 인성과의 관련성 연구 (Interrelations Among Beverage Intake, Food Behavior and Personality in Adolescents)

  • 허은실;이경혜;배은영;류은순
    • 대한지역사회영양학회지
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    • 제13권2호
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    • pp.189-198
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    • 2008
  • This study investigated the influences of the beverage intake on food behavior and personality for 1295 adolescents. The results were as follows. The favorite beverage was 'fruit juice', and preference of 'coffee' was the lowest. 'Milk and dairy product' was highest and 'milkshake' was lowest in intake frequency of beverage. The preference correlated positively(r = 0.391) with the intake frequency of beverage, especially high in 'green tea and black tea'(r = 0.622), 'coffee'(r = 0.581), 'carbonated drink'(r = 0.538), and 'milk and dairy product'(r = 0.501). The explanation power(R2) of beverage preference on beverage intake was 0.153. The explanation power($R^2$) of beverage intake on food behavior was 0.127, and 'carbonated drink' and 'coffee' as well as 'milkshake' had a negative influence on food behavior: however, 'milk and dairy product', 'green tea and black tea', and 'fruit juice' had a positive influence on food behavior. The relationship of beverage intake and sociality was very low($R^2$= 0.013), and 'isotonic drink' and 'green tea and black tea' had a positive influence on sociality. The relationship between beverage intake and anger expression was also very low. 'Coffee' showed a positive relationship with anger-in. 'Carbonated drink' and 'milkshake' showed a positive result with anger-out. 'Milkshake' showed a negative relation with anger-control, but 'green tea and black tea' and 'milk and dairy product' showed a positive relation. From these results, it was necessary to develop the practical nutritioneducation program on proper beverage choice for adolescents leading to better metal and physical status.

사용자 감정 예측을 통한 상황인지 추천시스템의 개선 (Improvement of a Context-aware Recommender System through User's Emotional State Prediction)

  • 안현철
    • Journal of Information Technology Applications and Management
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    • 제21권4호
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    • pp.203-223
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    • 2014
  • This study proposes a novel context-aware recommender system, which is designed to recommend the items according to the customer's responses to the previously recommended item. In specific, our proposed system predicts the user's emotional state from his or her responses (such as facial expressions and movements) to the previous recommended item, and then it recommends the items that are similar to the previous one when his or her emotional state is estimated as positive. If the customer's emotional state on the previously recommended item is regarded as negative, the system recommends the items that have characteristics opposite to the previous item. Our proposed system consists of two sub modules-(1) emotion prediction module, and (2) responsive recommendation module. Emotion prediction module contains the emotion prediction model that predicts a customer's arousal level-a physiological and psychological state of being awake or reactive to stimuli-using the customer's reaction data including facial expressions and body movements, which can be measured using Microsoft's Kinect Sensor. Responsive recommendation module generates a recommendation list by using the results from the first module-emotion prediction module. If a customer shows a high level of arousal on the previously recommended item, the module recommends the items that are most similar to the previous item. Otherwise, it recommends the items that are most dissimilar to the previous one. In order to validate the performance and usefulness of the proposed recommender system, we conducted empirical validation. In total, 30 undergraduate students participated in the experiment. We used 100 trailers of Korean movies that had been released from 2009 to 2012 as the items for recommendation. For the experiment, we manually constructed Korean movie trailer DB which contains the fields such as release date, genre, director, writer, and actors. In order to check if the recommendation using customers' responses outperforms the recommendation using their demographic information, we compared them. The performance of the recommendation was measured using two metrics-satisfaction and arousal levels. Experimental results showed that the recommendation using customers' responses (i.e. our proposed system) outperformed the recommendation using their demographic information with statistical significance.

변화하는 한국사회에 있어서 고부 갈등에 관한 연구 (A Study of Conflict between Monther-in-law and daughter-in-law in the Changing Korean society with Special reference to Pusan Area)

  • 고정자
    • 대한가정학회지
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    • 제26권4호
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    • pp.129-160
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    • 1988
  • The purpose of the present study is to understand the change in the relation between mother-in-law and daughter-in-law according to the social change in comparison with the survey effects in 1974 (ko Jung-Ja) and 1985 to find out the cause of conflict in both side of power structure and affection structure, indicating behavior, the influences on the relationships among family, possible meditators. this thesis was made by an experimental research. Data were collected from 146 mothers-in-law and 141 daughters-in-law in Pusan. The collected data were analysed by statistical methods such is as follows, 1. cause of conflict In power structure the cause of conflict is, in the case of mother-in-law opinion opposion and shaughty attitude by daughter in-low and, in the case of daughter-in-law, domestic dominance. It is thought that there is a difference of viw\ew between mother-in-law and daughter-in-law about the possesion of economic dominance and many conflicts rises because of economic dominance. but the study in 1985 than 1974 suggests the possibility of conflict meditator because mother-in-law and daughter-in-law do homework dependently in the practice of power. In affection structure, the chief dissatisfaction toward daughter-in-law showes the change in time. In 1974, there was no affection and respect. In 1985, the rate of doing without consultation was high. Also, the lack of communication of mother-in-law and daughter-in-law is the cause of conflict. 2. Indicating behavior the rate of thinking alone if high in both sides. But in the survey of 1985, the covert verbal aggressive action with which mother-in-law appeals to her daughter and daughter-in-law to husband is rising. 3. Influence on the relationship among family by the conflict between mother-in-law and daughter-in-law. the conflict between mother-in-law and daughter-in-law play negative effects on the intimacy and relation between husband and wife. 4. Conflict mediation behavior As compremiser, it is suggested that in the case of daughter-in-law the position and role of husband is important and, in the case of mother-in-law respects mother-in-law, daughter-in-law and gives her the role.

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영상에 의해 유발된 부정적 감정 상태에 따른 전두엽 감마대역 신경동기화 (Frontal Gamma-band Hypersynchronization in Response to Negative Emotion Elicited by Films)

  • 김현;최종두;최정우;여동훈;서부경;허성진;김경환
    • 대한의용생체공학회:의공학회지
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    • 제39권3호
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    • pp.124-133
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    • 2018
  • We tried to investigate the changes in cortical activities according to emotional valence states during watching video clips. We examined the neural basis of two emotional states (positive and negative) using spectral power analysis and brain functional connectivity analysis of cortical current density time-series reconstructed from high-density electroencephalograms (EEGs). Fifteen healthy participants viewed a series of thirty-two 2 min emotional video clips. Sixty-four channel EEGs were recorded. Distributed cortical sources were reconstructed using weighted minimum norm estimation. The temporal and spatial characteristics of spectral source powers showing significant differences between positive and negative emotion were examined. Also, correlations between gamma-band activities and affective valence ratings were determined. We observed the changes of cortical current density time-series according to emotional states modulated by video clip. Gamma-band activities showed significant difference between emotional states for thirty seconds at the middle and the latter half of the video clip, mainly in prefrontal area. It was also significantly anti-correlated with the self-ratings of emotional valence. In addition, the gamma-band activities in frontal and temporal areas were strongly phase-synchronized, more strongly for negative emotional states. Cortical activities in frontal and temporal areas showed high spectral power and inter-regional phase synchronization in gamma-band during negative emotional states. It is inferred that the higher amygdala activation induced by negative stimuli resulted in strong emotional effects and caused strong local and global synchronization of neural activities in gamma-band in frontal and temporal areas.

산화물계 NTC 서미스터의 특성 (Properties of Oxide Systems for NTC Thermistors)

  • 이승관;이해연;이선학;허정섭;김현식;오영우
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 1999년도 하계학술대회 논문집 D
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    • pp.1855-1857
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    • 1999
  • $Mn_{1-x}Fe_{2+x}O_4$, $Mg_{1-x}Fe_{2+x}O_4$ (x=0.0, 0.025, 0.1, 0.2) for negative temperature coefficient (NTC) thermistor were prepared by calcining at $800^{\circ}C$ and sintering from 1100 to $1250^{\circ}C$ with $50^{\circ}C$ intervals. The best linear property was obtained in the Mn-based sample sintered at $1200^{\circ}C$ with x=0.0 composition. Temperature coefficient of resistance, $\alpha$, was -3.0 %/$^{\circ}C$ in the Mg-based sample at $25^{\circ}C$. Thermistor parameter, B, was in the range of 2500 [K] $\sim$7400 [K]. The results show the possibility that Mn-Ni-Co based thermistor could be substituted by the composition used in this study.

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인터넷 쇼핑몰 고객의 신뢰 및 결속에 미치는 고객불만의 부정적 영향: 불평처리 공정성 지각의 조절효과 (Dissatisfaction, Trust, Commitment, and Repurchasing Intention of Internet Shopping Mall: The Moderating Effect of Perceived Equity to Complaint Handling)

  • 박경도;박진용;서지연
    • 한국유통학회지:유통연구
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    • 제11권2호
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    • pp.59-79
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    • 2006
  • 고객불만에 대한 대응은 고객과의 관계를 형성하고자 하는 기업목표 달성에 매우 중요한 요소가 된다. 인터넷 상거래 상장에서, 다양한 대안 그리고 낮은 전환 비용 등의 특성 때문에 고객불만에 대한 효과적인 대처는 오프라인 시장에 비해서 그 중요성이 더욱 강조되고 있다. 본 연구에서는 인터넷 쇼핑몰의 불평처리를 경험한 고객들을 대상으로 1) 불만 (상품관련, 쇼핑몰관련)이 쇼핑몰과 고객간의 관계형성에 미치는 부정적인 영향에 대해 확인하고, 2) 불평처리의 세 가지 공정성(분배적, 절차적, 상호적) 지각이 불만과 신뢰 및 결속몰입간의 관계에 어떠한 조절효과를 갖는지 검증하였다. 상품관련 불만과 결속과의 관계를 제외하고, 대체적으로 불만은 신뢰와 결속에 부정적인 영향을 미치는 것으로 나타났다. 조절효과에서는 분배적 공정성이 확보된 경우 불만과 신뢰 및 결속의 부정적 관계가 대체적으로 완화되었으며, 절차적 공정성의 확보는 상품관련 불만이 신뢰와 결속에 미치는 부정적 관계를 상호적 공정성의 확보는 불만과 신뢰의 부정적 관계를 완화하는 것으로 나타났다.

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산후우울 사정을 위한 도구 개발 연구 (A Study on the Development of a Postpartum Depression Scale)

  • 배정이
    • 대한간호학회지
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    • 제27권3호
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    • pp.588-600
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    • 1997
  • Postpartum depression is one of the most serious problems in maternal health because it affects not only the mother but also her family. Postpartum depression disturbs the maternal-infant interaction and attachment. However, most postpartum depression patients ignore this problem and do not seek treatment. Many clinicians and researchers realiza there is a need to develop a postpartum depression scale. Thus, this study has been designed to development of a postpartum depression scale. Data were collected through a survey over a period of three months. Subjects who participated in the study were 167 Korean mothers in their postpartum period. The author used a convenience sampling method. The analysis of the data was done with SPSS PC/sup +/ for descriptive statistics, item analysis and factor analysis. Initially 62 items were generated from the interview data of eight postpartum depression patients and from a literature review. This preliminary scale was analyzed for reliability and validity. The results of this analysis are as follows. 1. Initially 62 items were analyzed through the Index of Content Validity(CVI) and 48 items were selected. 2. Seven factors were extracted through the principal component analysis, and these contributed 61% of the variance in the total score. Finally 46 items in the scale loaded .41∼ .84 on one of seven factors. 3. Each factor was labeled. Factor 1 was labeled 'emotional phenomena-emotional upset' and included 13 items, factor 2 was labeled' cognitive phenomena-self concept disturbance' and included seven items, factor 3 was labeled 'relationship to baby-negative feeling' and included six items, factor 4 was labeled 'relationship to baby- overload' and included eight items, factor 5 was labeled 'negative maternal identity' and included five items, factor 6 was labeled 'biophysiological phenomena-disturbance of physical functioning' and included four items, and factor 7 was labeled' interpersonal relationship phenomena-blamed others' and included three items. 4. Cronbach Coefficient Alpha for internal consistency was .95 for the total 46 items. Finally, the author suggests that this scale could be adequately applied in assessing the postpartum depression of mothers during the postpartum period. The results of this study can contribute to designing an appropriate postpartum depression prevention strategy.

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