• Child Health Nursing Research
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• v.18 no.4
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• pp.201-206
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• 2012

Purpose: In this study changes were observed in body temperature, heart rate and arterial oxygen saturation (SaO2) of newborns after bathing and to determine the effects of covering their heads with cotton hats after bathing. Methods: Participants were 58 newborn infants, 31 in the experimental group had their heads covered with cotton hats after their bath while 27 in the control group did not. Body temperature, arterial oxygen saturation and heart rate were measured at 8 consecutive times after bathing. Data were analyzed using t-test and repeated measures ANOVA. Results: Body temperature declined shortly after bathing. The experimental group showed faster recovery (p<.001). Heart rate increased after bathing in both groups. Heart rate in the experimental group decreased for 120 minutes and gradually increased to baseline (p<.001). In the control group, heart rate decreased for 180 minutes and then increased but did not reach the baseline (p<.001). Arterial oxygen saturation decreased shortly after bathing and recovery to the baseline was more rapid in the experimental group (30 minutes vs. 60 minutes) (p<.001). Conclusion: With significant changes observed in newborns' body temperature, arterial oxygen saturation and heart rate, covering the head right after bathing is effective in stabilizing infants' physiological system.

• Journal of Korean Society of Occupational and Environmental Hygiene
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• v.29 no.3
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• pp.368-374
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• 2019

Objectives: To examine the associations of borg's scale with actual heart rates of workers and energy consumption during their physical work. Methods: A total of 72 workers performing physical activities in postal service, ceramic manufacturing, and metal manufacturing participated in heart rate measurement for 1 work shift using the activity meter(A360) and responded to a borg's scale questionnaire. Results: In consistent with previous findings, we presented high correlation between borg's scale and energy consumption measures among workers performing physical activities(r=0.89) while post-work average heart rate showed nearly no correlation with post-work borg's scale (r=0.09). We proposed a set of adjustments when using borg's scale to estimate physical workload for those workers engaged in physical activities during the majority of their work shift. Conclusions: Our findings suggest that a caution should be paid to when using Borg's scale to estimate heart rates during physical activities as well as energy consumption as the product of heart rate measurements.

• Child Health Nursing Research
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• v.25 no.3
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• pp.262-272
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• 2019

Purpose: We aimed to identify factors influencing physical activity in adolescents with complex congenital heart disease. Methods: We recruited 92 adolescents with complex congenital heart disease from a tertiary medical center in Seoul, measured their levels of physical activity, and identified factors that influenced their physical activity levels using the Global Physical Activity Questionnaire, the New York Heart Association classification, congenital heart disease complexity, the Self-Efficacy Scale, and the Parental Bonding Instrument scale. Stepwise multiple linear regression was used to determine factors influencing physical activity. Results: Total physical activity was higher in males than in females (t=4.46, p<.001). Adolescents who participated in school physical education classes engaged in more physical activity than those who did not (t=6.77, p<.001). Higher self-efficacy (${\beta}=.41$, p<.001), male gender (${\beta}=.37$, p<.001) and participation in school physical education classes (${\beta}=.19$, p=.042) were associated with a higher likelihood of engagement in physical activity. Conclusion: It is necessary to develop nursing interventions that enhance self-efficacy in order to promote physical activity in adolescents with complex congenital heart disease. Physical activity should also be promoted in an individualized manner, taking into account gender, disease severity, and parental attitude.

• Biomedical Science Letters
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• v.30 no.1
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• pp.10-16
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• 2024

Oxidative stress caused by elevated reactive oxygen species (ROS) in the heart causes various heart diseases. Oxidative stress is known as a factor that causes diseases in various organs as well as the heart. Diseases such as heart failure, myocardial infarction, and cardiomyopathy caused by oxidative stress in the heart can be treated with medication or surgery. Recently, blood cells concentrate (BCC) is used in various treatment areas such as orthopedics, gynecology, and urology. BCC therapy is applied to treatment by concentrating platelets and white blood cells necessary for regeneration through simple centrifugation using autologous blood. As the platelets are activated, many growth factors are released from alpha granules of the platelets. Growth factors such as TGF-β1, PDGF, VEGF, and EGF derived from platelets are involved in various cell signaling pathway. Due to these growth factors, BCC can contribute to tissue regeneration and can treat various diseases. CD34+ cells contained in BCC may also play an important role in tissue regeneration. In this study, we investigated whether BCC has a regenerative effect on heart disease, and if so, what mechanism causes the effect. To observe this, cardiomyocyte cells were treated with H₂O₂ to induce oxidative stress. And the effect was confirmed in the presence or absence of BCC. As a result, in the presence of BCC, the oxidative stress of cardiomyocyte cells was reduced and cell damage was also reduced. These results suggest that BCC therapy can be a new treatment alternative for heart disease.

• International Journal of Internet, Broadcasting and Communication
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• v.16 no.3
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• pp.290-297
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• 2024

We investigate the efficacy of ensemble learning methods, specifically the soft voting technique, for enhancing heart disease prediction accuracy. Our study uniquely combines Logistic Regression, SVM with RBF Kernel, and Random Forest models in a soft voting ensemble to improve predictive performance. We demonstrate that this approach outperforms individual models in diagnosing heart disease. Our research contributes to the field by applying a well-curated dataset with normalization and optimization techniques, conducting a comprehensive comparative analysis of different machine learning models, and showcasing the superior performance of the soft voting ensemble in medical diagnosis. This multifaceted approach allows us to provide a thorough evaluation of the soft voting ensemble's effectiveness in the context of heart disease prediction. We evaluate our models based on accuracy, precision, recall, F1 score, and Area Under the ROC Curve (AUC). Our results indicate that the soft voting ensemble technique achieves higher accuracy and robustness in heart disease prediction compared to individual classifiers. This study advances the application of machine learning in medical diagnostics, offering a novel approach to improve heart disease prediction. Our findings have significant implications for early detection and management of heart disease, potentially contributing to better patient outcomes and more efficient healthcare resource allocation.

• Journal of Chest Surgery
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• v.13 no.4
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• pp.338-345
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• 1980

We have modified an isolated perfusion rat heart model of cardiopulmonary bypass, with which we are able to screen the effects of various cardioplegic solutions and hypothermia upon the ability of the heart to survivie during and recover from period of ischemic arrest. The modified experimental model was differed from the original as follow : a heat coil chamber of atrial and aortic reservoir provided temperature control, and the perfusate was gassed with each pure oxygen and pure carbon dioxide in 95:5 ratio. The Langendorff perfusion was initiated for a 10 minute period by introducing perfusate at $37^{\circ}C.$ into the aorta from the aortic reservoir located 100 cm above the heart. The isolated perfused working rat heart model was a left heart preparation in which oxygenated perfusion medium (at $37^{\circ}C.$) entered the cannulated left atrium at a pressure of 20 cm $H_{2}O$ and was passed to the ventricle, from which it was sponeously elected(no electrical pacing) via an aortic cannula, against a hydrostatic pressure of 100cm $H_{2}O$. during this working period various indices of cardiac functin were measured. The cardiac functions were stable for over 3 hour with perfusion of Krebs-Henseleit bicarbonate buffer solution containing only glucose (11.1 mM/L). The percentage of cardiac functins were maintained about 94% on heart rate, 80.6% on peak aortic pressure, 87.7% on coronary flow and 76.3% on aortic flow rate after 3 hour of working heart perfusion at a pressure of 20 cm $H_{2}O$. We believe this preparation to be a good biochemical model for the human heart which offers many advantages including economic, speed of preparation, reproducibility, and the ability to handle large numbers.

• Journal of Physiology & Pathology in Korean Medicine
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• v.16 no.5
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• pp.881-887
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• 2002

This treatise is written in order to solve the important contradiction between the two theories; in oriental medicine psychological function is responsible for heart, but in western one it is responsible for brain. So we take the methods of studying in the aspects of morphological characteristics(MC) and visceral manifestation theory(VMT, 藏象論) and others about two organs-heart and brain. Brain(頭腦) is preferred to understand as a structure which is manifesting mental activity of heart. So the brain can be named with external heart(外心) corresponding to the relation of kidney(外 and external kidney. Saying conversely, the nutritional foundation of the mental function is the blood of heart, but the enlightening and insightful features of mentality make it's own residence move to the organ in the uppermost and positive site, that is head. And the close relationships on mental functions between heart and brain were discussed in various aspects, like investigation on east and west etymological literature, or Jiu gong and Taoist theory as well as Me and VMT, These understandings can make us know about the pathology of brain by itself. It has deep relations with heart fire and heart blood and kidney essence, and gastrointestinal function and liver with lung additionally. In another point, it makes the highly complicated psychological functions to be explained free from body relatively, and so can do a role in the complement of the strict 5 viscera theory.

• The Journal of Internal Korean Medicine
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• v.38 no.6
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• pp.877-890
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• 2017

Objectives: Lonicerae flos (LF), a dried flower part of Lonicera japonica Thunb., has been widely used in Korean medicine as anti-inflammatory and antioxidative agent. The purpose of this study was to determine the cardioprotective effects of LF, through potential antioxidant effects, on the pressure overload (PO)-induced heart failure (HF) in C57BL/6 mice after transverse aortic constriction (TAC) surgery. Methods: Resveratrol (10 mg/kg body weight) or LF (125, 250 or 500 mg/kg body weight) was orally administered, once daily for 14 days, starting 14 days after TAC surgery. Changes in the mortality, body weights, heart weights, histopathology of the heart, and antioxidant defense systems of the heart were analyzed. Results: Marked and noticeable increases of heart weights, mortalities, and hypertrophic, focal, and lytic fibrotic histological changes in the LVs were observed, with destruction of heart antioxidant defense systems after surgery. However, HF signs, induced by TAC surgery through PO, and destruction of heart antioxidant defense systems were significantly and dose-dependently inhibited by 14 days of maintained oral treatment with LF 500, 250 or 125 mg/kg. Treatment with 250 mg/kg LF was comparable to treatment with 10 mg/kg resveratrol. Conclusions: The results in this study suggest that oral administration of LF favorably relieves PO-induced HF following TAC, through increase of heart antioxidant defense systems. The overall effects of 250 mg/kg LF were similar to those of 10 mg/kg resveratrol. More detailed mechanistic studies should be conducted in the future, with screening of the biologically active compounds in LF.

• Korean Journal of Psychosomatic Medicine
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• v.12 no.1
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• pp.3-14
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• 2004

In this article, the effects of stress on central nerve system and heart function and the concept of heart rate variability were reviewed. HRV(Heart Rate Variability), the periodical change of the heart rate, is indicated larger in the healthier because they respond flexibly to various sorts of facts influencing on HR. HRV analysis is largely composed of the time domain analysis and the frequency analysis. In the former the flexibility of heart function is analysed, while in the latter autonomic nerve function is examined, which is the degree of sympathetic and parasympathetic nerve activity and the state of balance. Furthermore, existence or nonexistence of disease and/or level of stress can be estimated by measuring the variability and normality of heart rate, and balance of autonomic nerve system, and through HRV biofeedback the symptoms of anxiety disorder or asthma can be reduced.

• Journal of Biomedical Engineering Research
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• v.3 no.1
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• pp.23-30
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• 1982

The regimen of physical activity of the patient with coronary artery disease requires that he should not overshoot the prescribed heart rate based on his age, health and fuctional status of the heart during his exercise. The step input of work load, however, involves a great danger of overshooting. The purpose of this study was to desigil a system that makes it passible for a subject to check the overshooting. This system shows on tile H.R-meter, the amplified and filtered heart-rate signal of the subject received by the photosensor on his earlobe, puts it in the lead coinpensational circuit where it is conpared with the reference input signal(=the presfribed heart rate). The output of the lead compensational circuit works the aull meter. By means of this null meter, the subject knows whether he is overshooting the prescribed heart rate or not. He can continue the natl meter needle at the'Zero'position through the control of the speed of pedaling of the bicycle ergometer, An experimental test, made on eight men and four women in healthy condition, showed that 91. 7% of them vlaintained the stable heart rate and that the overshooting of the desired heart rate did not exceed $\pm$2BPM. According to the result of this experiment, since the heart rate feedback controller makes it possible for the subject to take the prescribed exercise based not on the work load but on the heart rate which incidentally is inexpensive, it can be made use of as the instrument for the regimen of pflysical activity by the patient with coronary artery disease.